Effects of six versus three times per week hemodialysis on physical performance, health, and functioning: Frequent hemodialysis network (FHN) randomized trials

Clinical Journal of the American Society of Nephrology

Volumn 7, Issue 5, 2012, Pages 782-794

  Hall, Yoshio N ^a   Larive, Brett ^b   Painter, Patricia ^c   Kaysen, George A ^d   Lindsay, Robert M ^e   Nissenson, Allen R ^f   Unruh, Mark L ^g   Rocco, Michael V ^h   Chertow, Glenn M ⁱ  

^a UNIVERSITY OF WASHINGTON   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF UTAH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e LONDON HEALTH SCIENCES CENTRE   (Canada)

^f DAVITA INC   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h WAKE FOREST SCHOOL OF MEDICINE   (United States)

ⁱ STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; UREA;

ADULT; ARTICLE; CREATININE CLEARANCE; FEMALE; FUNCTIONAL STATUS; HEALTH STATUS; HEMODIALYSIS; HUMAN; INTERMETHOD COMPARISON; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; LIFE EXPECTANCY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PHYSICAL ACTIVITY; PHYSICAL PERFORMANCE; POPULATION; PROSPECTIVE STUDY; QUALITY OF LIFE; SCORING SYSTEM; SELF REPORT;

ADULT; AGED; EXERCISE TEST; FEMALE; HEALTH STATUS; HEMODIALYSIS, HOME; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PHYSICAL FITNESS; QUALITY OF LIFE; QUESTIONNAIRES; RENAL DIALYSIS; SELF REPORT;

EID: 84860714431     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.10601011     Document Type: Article

References (53)

1. Kurella Tamura M, Covinsky KE, Chertow GM, Yaffe K, Landefeld CS, McCulloch CE: Functional status of elderly adults before and after initiation of dialysis. N Engl J Med 361: 1539-1547, 2009
2. Evans RW, Manninen DL, Garrison LP Jr, Hart LG, Blagg CR, Gutman RA, Hull AR, Lowrie EG: The quality of life of patients with end-stage renal disease. N Engl J Med 312: 553-559, 1985
3. CookWL, Jassal SV: Functional dependencies among the elderly on hemodialysis. Kidney Int 73: 1289-1295, 2008
4. Kaysen GA, Larive B, Painter P, Craig A, Lindsay RM, Rocco MV, Daugirdas JT, Schulman G, Chertow GM; FHN Trial Group: Baseline physical performance, health, and functioning of participants in the Frequent Hemodialysis Network (FHN) trial. Am J Kidney Dis 57: 101-112, 2011
5. Unruh M, Benz R, Greene T, Yan G, Beddhu S, DeVita M, Dwyer JT, Kimmel PL, Kusek JW, Martin A, Rehm-McGillicuddy J, Teehan BP, Meyer KB; HEMO Study Group: Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO Study. Kidney Int 66: 355-366, 2004
6. Johansen KL: Physical functioning and exercise capacity in patients on dialysis. Adv Ren Replace Ther 6: 141-148, 1999
7. Johansen KL, Chertow GM, Ng AV, Mulligan K, Carey S, Schoenfeld PY, Kent-Braun JA: Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney Int 57: 2564-2570, 2000
8. Johansen KL, Kaysen GA, Young BS, Hung AM, da Silva M, Chertow GM: Longitudinal study of nutritional status, body composition, and physical function in hemodialysis patients. Am J Clin Nutr 77: 842-846, 2003
9. Lacson E Jr, Xu J, Lin SF, Dean SG, Lazarus JM, Hakim RM: A comparison of SF-36 and SF-12 composite scores and subsequent hospitalization and mortality risks in long-term dialysis patients. Clin J Am Soc Nephrol 5: 252-260, 2010
10. DeOreo PB: Hemodialysis patient-assessed functional health status predicts continued survival, hospitalization, and dialysisattendance compliance. Am J Kidney Dis 30: 204-212, 1997
11. Mapes DL, Bragg-Gresham JL, Bommer J, Fukuhara S, McKevitt P, Wikström B, Lopes AA: Health-related quality of life in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 44[Suppl 2]: 54-60, 2004
12. Knight EL, Ofsthun N, Teng M, Lazarus JM, Curhan GC: The association between mental health, physical function, and hemodialysis mortality. Kidney Int 63: 1843-1851, 2003
13. Hartmann EL, Kitzman D, Rocco M, Leng X, Klepin H, Gordon M, Rejeski J, Berry M, Kritchevsky S: Physical function in older candidates for renal transplantation: An impaired population. Clin J Am Soc Nephrol 4: 588-594, 2009
14. Unruh M, Miskulin D, Yan G, Hays RD, Benz R, Kusek JW, Meyer KB; HEMO Study Group: Racial differences in health-related quality of life among hemodialysis patients. Kidney Int 65: 1482-1491, 2004
15. Chen JL, Godfrey S, Ng TT, Moorthi R, Liangos O, Ruthazer R, Jaber BL, Levey AS, Castaneda-Sceppa C: Effect of intra-dialytic, low-intensity strength training on functional capacity in adult haemodialysis patients: A randomized pilot trial. Nephrol Dial Transplant 25: 1936-1943, 2010
16. Painter P, Carlson L, Carey S, Paul SM, Myll J: Physical functioning and health-related quality-of-life changes with exercise training in hemodialysis patients. Am J Kidney Dis 35: 482-492, 2000
17. Painter PL, Hector L, Ray K, Lynes L, Dibble S, Paul SM, Tomlanovich SL, Ascher NL: A randomized trial of exercise training after renal transplantation. Transplantation 74: 42-48, 2002
18. Painter P, Hanson P, Messer-Rehak D, Zimmerman SW, Glass NR: Exercise tolerance changes following renal transplantation. Am J Kidney Dis 10: 452-456, 1987
19. Johansen KL, Painter PL, Sakkas GK, Gordon P, Doyle J, Shubert T: Effects of resistance exercise training and nandrolone decanoate on body composition and muscle function among patients who receive hemodialysis: A randomized, controlled trial. J AmSoc Nephrol 17: 2307-2314, 2006
20. Storer TW, Casaburi R, Sawelson S, Kopple JD: Endurance exercise training during haemodialysis improves strength, power, fatigability and physical performance in maintenance haemodialysis patients. Nephrol Dial Transplant 20: 1429-1437, 2005
21. Ting GO, Kjellstrand C, Freitas T, Carrie BJ, Zarghamee S: Longterm study of high-comorbidity ESRD patients converted from conventional to short daily hemodialysis. Am J Kidney Dis 42: 1020-1035, 2003
22. Culleton BF, Walsh M, Klarenbach SW, Mortis G, Scott-Douglas N, Quinn RR, Tonelli M, Donnelly S, Friedrich MG, Kumar A, Mahallati H, Hemmelgarn BR, Manns BJ: Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: A randomized controlled trial. JAMA 298: 1291-1299, 2007
23. Kooistra MP, Vos J, Koomans HA, Vos PF: Daily home haemodialysis in The Netherlands: effects on metabolic control, haemodynamics, and quality of life. Nephrol Dial Transplant 13: 2853-2860, 1998
24. Chan CT, Notarius CF, Merlocco AC, Floras JS: Improvement in exercise duration and capacity after conversion to nocturnal home haemodialysis. Nephrol Dial Transplant 22: 3285-3291, 2007
25. Depner TA: Daily hemodialysis efficiency: An analysis of solute kinetics. Adv Ren Replace Ther 8: 227-235, 2001
26. Kaysen GA, Zhu F, Sarkar S, Heymsfield SB, Wong J, Kaitwatcharachai C, Kuhlmann MK, Levin NW: Estimation of total-body and limb muscle mass in hemodialysis patients by using multifrequency bioimpedance spectroscopy. Am J Clin Nutr 82: 988-995, 2005
27. Painter P, Krasnoff JB, Kuskowski M, Frassetto L, Johansen KL: Effects ofmodality change and transplant on peak oxygen uptake in patients with kidney failure. Am J Kidney Dis 57: 113-122, 2011
28. Galland R, Traeger J, Arkouche W, Cleaud C, Delawari E, Fouque D: Short daily hemodialysis rapidly improves nutritional status in hemodialysis patients. Kidney Int 60: 1555-1560, 2001
29. Chertow GM, Levin NW, Beck GJ, Depner TA, Eggers PW, Gassman JJ, Gorodetskaya I, Greene T, James S, Larive B, Lindsay RM, Mehta RL, Miller B, Ornt DB, Rajagopalan S, Rastogi A, Rocco MV, Schiller B, Sergeyeva O, Schulman G, Ting GO, Unruh ML, Star RA, Kliger AS; FHN Trial Group: In-center hemodialysis six times perweek versus three times perweek.NEngl J Med 363: 2287-2300, 2010
30. Suri RS, Garg AX, Chertow GM, Levin NW, Rocco MV, Greene T, Beck GJ, Gassman JJ, Eggers PW, Star RA, Ornt DB, Kliger AS; Frequent Hemodialysis Network Trial Group: Frequent Hemodialysis Network (FHN) randomized trials: study design. Kidney Int 71: 349-359, 2007
31. Rocco MV, Larive B, Eggers PW, Beck GJ, Chertow GM, Levin NW, Kliger AS; FHN Trial Group: Baseline characteristics of participants in the Frequent Hemodialysis Network (FHN) daily and nocturnal trials. Am J Kidney Dis 57: 90-100, 2011
32. Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB: Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N Engl J Med 332: 556-561, 1995
33. Hays RD, Morales LS: The RAND-36 measure of health-related quality of life. Ann Med 33: 350-357, 2001
34. Johansen KL, Painter P, Kent-Braun JA, Ng AV, Carey S, Da Silva M, Chertow GM: Validation of questionnaires to estimate physical activity and functioning in end-stage renal disease. Kidney Int 59: 1121-1127, 2001
35. Painter P: Physical functioning in end-stage renal disease patients: Update 2005. Hemodial Int 9: 218-235, 2005
36. Unruh M, Yan G, Radeva M, Hays RD, Benz R, Athienites NV, Kusek J, Levey AS, Meyer KB; HEMO Study Group: Bias in assessment of health-related quality of life in a hemodialysis population: A comparison of self-administered and intervieweradministered surveys in the HEMO study. J Am Soc Nephrol 14: 2132-2141, 2003
37. Hemmelgarn BR, Manns BJ, Quan H, Ghali WA: Adapting the Charlson Comorbidity Index for use in patients with ESRD. Am J Kidney Dis 42: 125-132, 2003
38. Miskulin DC, Athienites NV, Yan G, Martin AA, Ornt DB, Kusek JW, Meyer KB, Levey AS; Hemodialysis (HEMO) Study Group: Comorbidity assessment using the Index of Coexistent Diseases in a multicenter clinical trial. Kidney Int 60: 1498-1510, 2001
39. Verbeke G, Molenbergh G: Linear Mixed Models for Longitudinal Data (Springer Series in Statistics), New York, Springer, 2000
40. Pahor M, Blair SN, Espeland M, Fielding R, Gill TM, Guralnik JM, Hadley EC, King AC, Kritchevsky SB, Maraldi C, Miller ME, Newman AB, Rejeski WJ, Romashkan S, Studenski S; LIFE Study Investigators: Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci 61: 1157-1165, 2006
41. Rocco MV, Lockridge RS Jr, Beck GJ, Eggers PW, Gassman JJ, Greene T, Larive B, Chan CT, Chertow GM, Copland M, Hoy CD, Lindsay RM, Levin NW, Ornt DB, Pierratos A, Pipkin MF, Rajagopalan S, Stokes JB, Unruh ML, Star RA, Kliger AS, Kliger A, Eggers P, Briggs J, Hostetter T, Narva A, Star R, Augustine B, Mohr P, Beck G, Fu Z, Gassman J, Greene T, Daugirdas J, Hunsicker L, Larive B, Li M, Mackrell J, Wiggins K, Sherer S, Weiss B, Rajagopalan S, Sanz J, Dellagrottaglie S, Kariisa M, Tran T, West J, Unruh M, Keene R, Schlarb J, Chan C, McGrath-Chong M, Frome R, Higgins H, Ke S, Mandaci O, Owens C, Snell C, Eknoyan G, Appel L, Cheung A, Derse A, Kramer C, Geller N, Grimm R, Henderson L, Prichard S, Roecker E, Rocco M, Miller B, Riley J, Schuessler R, Lockridge R, Pipkin M, Peterson C, Hoy C, Fensterer A, Steigerwald D, Stokes J, Somers D, Hilkin A, Lilli K, Wallace W, Franzwa B, Waterman E, Chan C, McGrath-Chong M, Copland M, Levin A, Sioson L, Cabezon E, Kwan S, Roger D, Lindsay R, Suri R, Champagne J, Bullas R, Garg A, Mazzorato A, Spanner E, Rocco M, Burkart J, Moossavi S, Mauck V, Kaufman T, Pierratos A, Chan W, Regozo K, Kwok S; Frequent Hemodialysis Network (FHN) Trial Group: The effects of frequent nocturnal home hemodialysis: The Frequent Hemodialysis Network Nocturnal Trial. Kidney Int 80: 1080-1091, 2011
42. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB: A short physical performance battery assessing lower extremity function: Association with selfreported disability and prediction of mortality and nursing home admission. J Gerontol 49: M85-M94, 1994
43. McDermott MM, Liu K, Ferrucci L, Criqui MH, Greenland P, Guralnik JM, Tian L, Schneider JR, Pearce WH, Tan J, Martin GJ: Physical performance in peripheral arterial disease: A slower rate of decline in patients who walk more. Ann Intern Med 144: 10-20, 2006
44. Johansen KL, Shubert T, Doyle J, Soher B, Sakkas GK, Kent-Braun JA: Muscle atrophy in patients receiving hemodialysis: Effects on muscle strength, muscle quality, and physical function. Kidney Int 63: 291-297, 2003
45. Walsh M, Culleton B, Tonelli M, Manns B: A systematic reviewof the effect of nocturnal hemodialysis on blood pressure, left ventricular hypertrophy, anemia, mineral metabolism, and health-related quality of life. Kidney Int 67: 1500-1508, 2005
46. Headley S, Germain M, Mailloux P, Mulhern J, Ashworth B, Burris J, Brewer B, Nindl BC, Coughlin M, Welles R, Jones M: Resistance training improves strength and functional measures in patients with end-stage renal disease. Am J Kidney Dis 40: 355-364, 2002
47. Kouidi E, Albani M, Natsis K, Megalopoulos A, Gigis P, Guiba-Tziampiri O, Tourkantonis A, Deligiannis A: The effects of exercise training on muscle atrophy in haemodialysis patients. Nephrol Dial Transplant 13: 685-699, 1998
48. Rampal P, Martin C, Marquis P, Ware JE, Bonfils S: A quality of life study in five hundred and eighty-one duodenal ulcer patients. Maintenance versus intermittent treatment with nizatidine. Scand J Gastroenterol Suppl 206: 44-51, 1994
49. Veenstra M, Pettersen KI, Rollag A, Stavem K: Association of changes in health-related quality of life in coronary heart disease with coronary procedures and sociodemographic characteristics. Health Qual Life Outcomes 2: 56, 2004
50. Suri RS, Nesrallah GE, Mainra R, Garg AX, Lindsay RM, Greene T, Daugirdas JT: Daily hemodialysis: a systematic review. Clin J Am Soc Nephrol 1: 33-42, 2006
51. Dwyer JT, Larive B, Leung J, Rocco M, Burrowes JD, Chumlea WC, Frydrych A, Kusek JW, Uhlin L; Hemodialysis Study Group: Nutritional status affects quality of life in Hemodialysis (HEMO) Study patients at baseline. J Ren Nutr 12: 213-223, 2002
52. Kalantar-Zadeh K, Block G, McAllister CJ, Humphreys MH, Kopple JD: Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients. Am J Clin Nutr 80: 299-307, 2004
53. Jaber BL, Lee Y, Collins AJ, Hull AR, Kraus MA, McCarthy J, Miller BW, Spry L, Finkelstein FO; FREEDOM Study Group: Effect of daily hemodialysis on depressive symptoms and postdialysis recovery time: Interim report from the FREEDOM (Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements) Study. Am J Kidney Dis 56: 531-539, 2010