The value of early second trimester PAPP-A and ADAM12 in screening for pre-eclampsia

Journal of Medical Screening

Volumn 19, Issue 1, 2012, Pages 51-54

  Bestwick, Jonathan P ^a   George, Lynne M ^a   Wu, Tiesheng ^a   Morris, Joan K ^a   Wald, Nicholas J ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM 12 PROTEIN; ADAM PROTEIN; BIOLOGICAL MARKER; MEMBRANE PROTEIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A;

ADULT; ARTICLE; BLOOD; CASE CONTROL STUDY; ETHNOLOGY; EVALUATION; FEMALE; GESTATIONAL AGE; HUMAN; MASS SCREENING; METHODOLOGY; PREDICTIVE VALUE; PREECLAMPSIA; PREGNANCY; PRENATAL DIAGNOSIS; SECOND TRIMESTER PREGNANCY; STANDARD;

ADAM PROTEINS; ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; GESTATIONAL AGE; HUMANS; MASS SCREENING; MEMBRANE PROTEINS; PRE-ECLAMPSIA; PREDICTIVE VALUE OF TESTS; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PRENATAL DIAGNOSIS;

EID: 84860638044     PISSN: 09691413     EISSN: 14755793     Source Type: Journal    
DOI: 10.1258/jms.2012.011085     Document Type: Article

References (16)

1. Kang JH, Farina A, Park JH, et al. Down syndrome biochemical markers and screening for pre-eclampsia at first and second trimester: correlation with the week of onset and the severity. Prenat Diagn 2008;28:704-9
2. Poon LCY, Chelemen T, Granvillano O, Pandeva I, Nicolaides KH. First-trimester maternal serum A Disintegrin and Metalloprotease 12 (ADAM12) and adverse pregnancy outcome. Obstet Gynecol 2008;112:1082-90
3. Spencer K, Cowans NJ, Nicolaides KH. Low levels of maternal serum PAPP-A in the first trimester and the risk of pre-eclamspia. Prenat Diagn 2008;28:7-10 (Pubitemid 351251982)
4. Poon LCY, Maiz N, Valencia C, PlasenciaW, Nicolaides KH. First-trimester maternal serum pregnancy-associated plasma protein-A and pre-eclamspia. Ultrasound Obstet Gynecol 2009;33:23-33
5. Audibert F, Boucoiran I, An N, et al. Screening for pre-eclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women. Am J Obstet Gynecol 2010;203:383.e1-8
6. Wortelboer EJ, Koster MPH, Cuckle HS, Stoutenbeek PH, Schielen PCJI, Visser GHA. First-trimester placental protein 13 and placental growth factor: markers for identification of women destined to develop early-onset pre-eclampsia. BJOG 2010;117:1384-9
7. Akolekar R, Syngelaki A, Sarquis R, Zvanca M, Nicolaides KH. Prediction of early, intermediate and late pre-eclampsia from maternal factors, biophysical and biochemical markers at 11-13 weeks. Prenat Diagn 2011;31:66-74
8. Sifakis S, Akolekar R, Mantas N, Kappou D, Nicolaides KH. Maternal serum human placental growth hormone (hPGH) at 11 to 13 weeks of gestation in pre-eclampsia. Hypertens Pregnancy 2011;30:74-82
9. Bersinger NA, Odegard A. Second- and third-trimester serum levels of placental proteins in pre-eclampsia and small-for-gestational age pregnancies. Acta Obstet Gynecol Scand 2004;83:37-45 (Pubitemid 38121729)
10. D'Anna R, Giordano D, Russo S, Santamaria A, Granese R, Corrado F. ADAM12 and PAPP-A at 14-17 weeks' gestation as biomarkers of pre-eclampsia. Prenat Diag 2011;31:602-4
11. Spencer K, Yu CKH, Savvidou M, Papageorghiou AT, Nicolaides KH. Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free b-human chorionic gonadotropin, activin A and inhibin A at 22+0 to 24+6 weeks' gestation. Ultrasound Obstet Gynecol 2006;27:658-63 (Pubitemid 43967369)
12. Laigaard J, Sørensen T, Placing S, et al. Reduction of the Disintegrin and Metalloprotease ADAM12 in pre-eclampsia. Obstet Gynecol 2005;106:144-9 (Pubitemid 40898447)
13. Spencer K, Cowas NJ, Stamatopoulou A. ADAM12s in maternal serum as a potential marker of pre-eclampsia. Prenat Diagn 2008;28:212-6 (Pubitemid 351427940)
14. Wald NJ, Morris JK, Ibison J, Wu T, George LM. Screening in early pregnancy for pre-eclampsia using Down syndrome Quadruple test markers. Prenat Diag 2006;26:559-64 (Pubitemid 43989192)
15. Cowans NJ, Stamatopoulou A, Hellström J, Mäkelä M-M, Spencer K. PAPP-A and free b-hCG stability in first trimester serum using PerkinElmer AutoDELFIAw and DELFIAw Xpress systems. Prenat Diagn 2010;30:127-32
16. Cowans NJ, Stamatopoulou A, Jaakohuhta S, Spencer K. ADAM-12 stability in first trimester maternal serum. Prenat Diagn 2010;30:555-60