Higher vs. lower fluid volume for septic shock: Clinical characteristics and outcome in unselected patients in a prospective, multicenter cohort

Critical Care

Volumn 16, Issue 3, 2012, Pages

  Smith, Søren H ^a   Perner, Anders ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INFUSION FLUID; BLOOD SUBSTITUTE; CRYSTALLOID; ISOTONIC SOLUTION;

ADULT; AGED; ARTICLE; BLOOD; CHI SQUARE TEST; COHORT ANALYSIS; CONTROLLED STUDY; CRYSTALLOID; FEMALE; FLUID THERAPY; HOSPITAL; HUMAN; INTENSIVE CARE UNIT; LIQUID; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEPTIC SHOCK; CLINICAL TRIAL; COMPARATIVE STUDY; DRUG EFFECTS; ELECTROLYTE BALANCE; MIDDLE AGED; MULTICENTER STUDY; PHYSIOLOGY; PROCEDURES; SHOCK, SEPTIC; TREATMENT OUTCOME;

ADULT; AGED; BLOOD SUBSTITUTES; COHORT STUDIES; FEMALE; FLUID THERAPY; HUMANS; ISOTONIC SOLUTIONS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SHOCK, SEPTIC; TREATMENT OUTCOME; WATER-ELECTROLYTE BALANCE;

EID: 84860633744     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11333     Document Type: Article

References (18)

1. Varpula M, Tallgren M, Saukkonen K, Voipio-Pulkki LM, Pettila V. Hemodynamic variables related to outcome in septic shock. Intensive Care Med 2005, 31:1066-1071. 10.1007/s00134-005-2688-z, 15973520.
2. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med 2008, 34:17-60. 10.1007/s00134-007-0934-2, 2249616, 18058085.
3. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001, 345:1368-1377. 10.1056/NEJMoa010307, 11794169.
4. Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, Moreno R, Carlet J, Le Gall JR, Payen D, . Sepsis Occurrence in Acutely Ill Patients Investigators Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006, 34:344-353. 10.1097/01.CCM.0000194725.48928.3A, 16424713, Sepsis Occurrence in Acutely Ill Patients Investigators.
5. Boyd JH, Forbes J, Nakada TA, Walley KR, Russell JA. Fluid resuscitation in septic shock: a positive fluid balance and elevated central venous pressure are associated with increased mortality. Crit Care Med 2011, 39:259-265. 10.1097/CCM.0b013e3181feeb15, 20975548.
6. Murphy CV, Schramm GE, Doherty JA, Reichley RM, Gajic O, Afessa B, Micek ST, Kollef MH. The importance of fluid management in acute lung injury secondary to septic shock. Chest 2009, 136:102-109. 10.1378/chest.08-2706, 19318675.
7. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20:864-874. 10.1097/00003246-199206000-00025, 1597042.
8. Carlsen S, Perner A. Initial fluid resuscitation of patients with septic shock in the intensive care unit. Acta Anaesthesiol Scand 2011, 55:394-400. 10.1111/j.1399-6576.2011.02399.x, 21342150.
9. Oldner A, Rossi P, Karason S, Aneman A. A practice survey on vasopressor and inotropic drug therapy in Scandinavian intensive care units. Acta Anaesthesiol Scand 2003, 47:693-701. 10.1034/j.1399-6576.2003.00129.x, 12803586.
10. FLUIDS study investigators for the Scandinavian Critical Care Trials Group Preference for colloid use in Scandinavian intensive care units. Acta Anaesthesiol Scand 2008, 52:750-758. FLUIDS study investigators for the Scandinavian Critical Care Trials Group.
11. De Backer D, Biston P, Devriendt J, Madl C, Chochrad D, Aldecoa C, Brasseur A, Defrance P, Gottignies P, Vincent JL. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010, 362:779-789. 10.1056/NEJMoa0907118, 20200382.
12. McIntyre LA, Fergusson D, Cook DJ, Nair RC, Bell D, Dhingra V, Hutton B, Magder S, Hebert PC. Resuscitating patients with early severe sepsis: a Canadian multicentre observational study. Can J Anaesth 2007, 54:790-798. 10.1007/BF03021706, 17934160.
13. Bayer O, Reinhart K, Sakr Y, Kabisch B, Kohl M, Riedemann NC, Bauer M, Settmacher U, Hekmat K, Hartog CS. Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: a prospective sequential comparison. Crit Care Med 2011, 39:1335-1342. 10.1097/CCM.0b013e318212096a, 21358396.
14. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004, 350:2247-2256.
15. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K, . German Competence Network Sepsis (SepNet) Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008, 358:125-139. 10.1056/NEJMoa070716, 18184958, German Competence Network Sepsis (SepNet).
16. Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee The Crystalloid versus Hydroxyethyl Starch Trial: protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality. Intensive Care Med 2011, 37:816-823. Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee.
17. Perner A, Haase N, Wetterslev J, Aneman A, Tenhunen J, Guttormsen AB, Klemenzson G, Pott F, Bødker KD, Bådstøløkken PM, Bendtsen A, Søe-Jensen P, Tousi H, Bestle M, Pawlowicz M, Winding R, Bülow HH, Kancir C, Steensen M, Nielsen J, Fogh B, Madsen KR, Larsen NH, Carlsson M, Wiis J, Petersen JA, Iversen S, Schøidt O, Leivdal S, Berezowicz P, et al. Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S - Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial. Trials 2011, 12:24. 10.1186/1745-6215-12-24, 3040153, 21269526.
18. Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999, 340:409-417. 10.1056/NEJM199902113400601, 9971864.