Changes on degranulation of mast cells and neurogenic inflammation-related factors in the dura mater of the rat model of migraine

Chinese Journal of Neurology

Volumn 44, Issue 8, 2011, Pages 563-567

  Xu, Wu ^a   Shi, Zhao Chun ^a   Wei, Jun Chao ^a   Cao, Yue Zhou ^a   Wu, Ting ^a   Wan, Qi ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Calcitonin gene related peptide; Cyclooxygenase 2; Dinoprostone; Mast cells; Migraine disorders

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CYCLOOXYGENASE 2; HISTAMINE; PROSTAGLANDIN E2; TOLUIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DURA MATER; ELECTROSTIMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTAMINE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; JUGULAR VEIN; MAST CELL DEGRANULATION; MIGRAINE; NERVE STIMULATION; NEUROGENIC INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; SHAM PROCEDURE; TRIGEMINUS GANGLION; WESTERN BLOTTING;

EID: 84860620945     PISSN: 10067876     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.1006-7876.2011.08.014     Document Type: Article

References (21)

1. 2006, 45: 694-696.
2. 1996, 2: 109-113.
3. Knyihár-Csillik E, Tajti J, Chadaide Z, et al. Functional immunohistoehemistry of neuropeptides and nitric oxide synthase in the nerve fibers of the supratentorial dura mater in an experimental migraine model. Microsc Res Tech, 2001, 53: 193-211.
4. Pietrobon D, Striessnig J. Neurobiology of migraine. Nat Rev Neurosci, 2003, 4: 386-398.
5. Goadsby P J. Recent advances in understanding migraine mechanisms, molecules and therapeutics. Trends Mol Med, 2007, 13: 39-44.
6. Moskowitz M A. Pathophysiology of Headache-past and present. Headache, 2007, 47 Suppl 1: S58-63.
7. Limmroth V, Katsarava Z, Liedert B, et al. An in vivo rat model to study calcitonin generelated peptide release following activation of the trigeminal vascular system. Pain, 2001, 92: 101-106.
8. Lennerz J K, Ruhle V, Ceppa E P, et al. Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1(RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distribution. J Comp Neurol, 2008, 507: 1277-1299.
9. Dan L. Meningeal mast cells, inflammation and migraine pain. Drug Development Research, 2007, 68: 412-418.
10. Ottosson A, Edvinsson L. Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide. Cephalalgia, 1997, 17: 166-174.
11. Schwenger N, Dux M, de Col R, et al. Interaction of calcitonin gene-related peptide, nitric oxide and histamine release in neurogenic blood flow and afferent activation in the rat cranial dura mater. Cephalalgia, 2007, 27: 481-491.
12. Theoharides T C, Donelan J, Kandere-Grzybowska K, et al. The role of mast cells in migraine pathophysiology. Brain Res Brain Res Rev, 2005, 49: 65-76.
13. Zhang X C, Strassman A M, Burstein R, et al. Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators. J Pharmacol Exp Ther, 2007, 322: 806-812.
14. Zhang X C, Levy D. Modulation of meningeal nociceptors mechanosensitivity by peripheral proteinase-activated receptor-2: the role of mast cells. Cephalalgia, 2008, 28: 276-284.
15. Levy D, Burstein R, Kainz V, et al. Mast cell degranulation activates a pain pathway underlyingmigraine headache. Pain, 2007, 130: 166-176.
16. Dimitriadou V, Buzzi M G, Moskowitz M A, et al. Trigeminal sensory fiber stimulation induces morphological changes reflecting secretion in rat dura mater mast cells. Neuroscience, 1991, 44: 97-112.
17. 2001, 22: 100-101.
18. Levy D, Burstein R, Strassman A M. Mast cell involvement in the pathophysiology of migraine headache: a hypothesis. Headache, 2006, 46 Suppl 1: S13-18.
19. 2009, 6: 47-51.
20. 2004, 20: 11-15.
21. Zhang X C, Kainz V, Jakubowski M, et al. Localization of COX-1 and COX-2 in the intracranial dura mater of the rat. Neurosci Lett, 2009, 452: 33-36.