메뉴 건너뛰기




Volumn 129, Issue 5, 2012, Pages

Pharmacologic treatment of repetitive behaviors in autism spectrum disorders: Evidence of publication bias

Author keywords

Antidepressive agents; Autism; Meta analysis; Pervasive child development disorders; Publication bias

Indexed keywords

CITALOPRAM; CLOMIPRAMINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; PAROXETINE; PLACEBO; SERTRALINE;

EID: 84860580549     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2011-3285     Document Type: Article
Times cited : (62)

References (59)
  • 1
    • 67049118065 scopus 로고    scopus 로고
    • Epidemiology of pervasive developmental disorders
    • Fombonne E. Epidemiology of pervasive developmental disorders. Pediatr Res. 2009;65(6):591-598
    • (2009) Pediatr Res , vol.65 , Issue.6 , pp. 591-598
    • Fombonne, E.1
  • 3
    • 79958258583 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorders in a total population sample
    • Kim YS, Leventhal BL, Koh YJ, et al. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry. 2011;168(9):904-912
    • (2011) Am J Psychiatry , vol.168 , Issue.9 , pp. 904-912
    • Kim, Y.S.1    Leventhal, B.L.2    Koh, Y.J.3
  • 4
    • 79958255914 scopus 로고    scopus 로고
    • Epidemiology: How common is autism?
    • Lord C. Epidemiology: How common is autism? Nature. 2011;474(7350):166- 168
    • (2011) Nature , vol.474 , Issue.7350 , pp. 166-168
    • Lord, C.1
  • 5
    • 0036674520 scopus 로고    scopus 로고
    • The autistic-spectrum disorders
    • Rapin I. The autistic-spectrum disorders. N Engl J Med. 2002;347(5):302-303
    • (2002) N Engl J Med , vol.347 , Issue.5 , pp. 302-303
    • Rapin, I.1
  • 6
    • 33846656723 scopus 로고    scopus 로고
    • Restricted and repetitive behaviors in young children with autism spectrum disorders
    • DOI 10.1007/s10803-006-0332-6, Special Issue: Early Autism Phenotype
    • Richler J, Bishop SL, Kleinke JR, Lord C. Restricted and repetitive behaviors in young children with autism spectrum disorders. J Autism Dev Disord. 2007;37(1):73-85 (Pubitemid 46197896)
    • (2007) Journal of Autism and Developmental Disorders , vol.37 , Issue.1 , pp. 73-85
    • Richler, J.1    Bishop, S.L.2    Kleinke, J.R.3    Lord, C.4
  • 7
    • 77950932517 scopus 로고    scopus 로고
    • Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders
    • Richler J, Huerta M, Bishop SL, Lord C. Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders. Dev Psychopathol. 2010;22(1):55-69
    • (2010) Dev Psychopathol , vol.22 , Issue.1 , pp. 55-69
    • Richler, J.1    Huerta, M.2    Bishop, S.L.3    Lord, C.4
  • 10
    • 59649101388 scopus 로고    scopus 로고
    • Similarities and differences between children and adolescents with autism spectrum disorder and those with obsessive compulsive disorder: Executive functioning and repetitive behaviour
    • Zandt F, Prior M, Kyrios M. Similarities and differences between children and adolescents with autism spectrum disorder and those with obsessive compulsive disorder: executive functioning and repetitive behaviour. Autism. 2009;13(1):43-57
    • (2009) Autism , vol.13 , Issue.1 , pp. 43-57
    • Zandt, F.1    Prior, M.2    Kyrios, M.3
  • 11
    • 33847213224 scopus 로고    scopus 로고
    • Repetitive behaviour in children with high functioning autism and obsessive compulsive disorder
    • Zandt F, Prior M, Kyrios M. Repetitive behaviour in children with high functioning autism and obsessive compulsive disorder. J Autism Dev Disord. 2007;37(2):251-259
    • (2007) J Autism Dev Disord , vol.37 , Issue.2 , pp. 251-259
    • Zandt, F.1    Prior, M.2    Kyrios, M.3
  • 12
    • 0033797682 scopus 로고    scopus 로고
    • Varieties of repetitive behavior in autism: Comparisons to mental retardation
    • Bodfish JW, Symons FJ, Parker DE, Lewis MH. Varieties of repetitive behavior in autism: comparisons to mental retardation. J Autism Dev Disord. 2000;30(3):237-243
    • (2000) J Autism Dev Disord , vol.30 , Issue.3 , pp. 237-243
    • Bodfish, J.W.1    Symons, F.J.2    Parker, D.E.3    Lewis, M.H.4
  • 13
    • 0028938464 scopus 로고
    • A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder
    • McDougle CJ, Kresch LE, Goodman WK, et al. A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder. Am J Psychiatry. 1995;152(5):772-777
    • (1995) Am J Psychiatry , vol.152 , Issue.5 , pp. 772-777
    • McDougle, C.J.1    Kresch, L.E.2    Goodman, W.K.3
  • 14
    • 0035497576 scopus 로고    scopus 로고
    • Obsessive compulsive behaviour in autism - Towards an autistic-obsessive compulsive syndrome?
    • Gross-Isseroff R, Hermesh H, Weizman A. Obsessive compulsive behaviour in autism - towards an autistic-obsessive compulsive syndrome? World J Biol Psychiatry. 2001;2(4):193-197
    • (2001) World J Biol Psychiatry , vol.2 , Issue.4 , pp. 193-197
    • Gross-Isseroff, R.1    Hermesh, H.2    Weizman, A.3
  • 15
    • 0037464828 scopus 로고    scopus 로고
    • Obsessive-compulsive behaviors in parents of multiplex autism families
    • DOI 10.1016/S0165-1781(02)00304-9, PII S0165178102003049
    • Hollander E, King A, Delaney K, Smith CJ, Silverman JM. Obsessive-compulsive behaviors in parents of multiplex autism families. Psychiatry Res. 2003;117(1):11-16 (Pubitemid 36173772)
    • (2003) Psychiatry Research , vol.117 , Issue.1 , pp. 11-16
    • Hollander, E.1    King, A.2    Delaney, K.3    Smith, C.J.4    Silverman, J.M.5
  • 16
    • 1242263492 scopus 로고    scopus 로고
    • The broad autism phenotype: Findings from an epidemiological survey
    • DOI 10.1177/1362361304040636
    • Micali N, Chakrabarti S, Fombonne E. The broad autism phenotype: findings from an epidemiological survey. Autism. 2004;8(1):21-37 (Pubitemid 38239620)
    • (2004) Autism , vol.8 , Issue.1 , pp. 21-37
    • Micali, N.1    Chakrabarti, S.2    Fombonne, E.3
  • 17
    • 70350029597 scopus 로고    scopus 로고
    • Cross-cutting issues and future directions for the OCD spectrum
    • Hollander E, Kim S, Braun A, Simeon D, Zohar J. Cross-cutting issues and future directions for the OCD spectrum. Psychiatry Res. 2009;170(1):3-6
    • (2009) Psychiatry Res , vol.170 , Issue.1 , pp. 3-6
    • Hollander, E.1    Kim, S.2    Braun, A.3    Simeon, D.4    Zohar, J.5
  • 18
    • 74249085453 scopus 로고    scopus 로고
    • Autism spectrum and obsessivecompulsive disorders: OC behaviors, phenotypes and genetics
    • Jacob S, Landeros-Weisenberger A, Leckman JF. Autism spectrum and obsessivecompulsive disorders: OC behaviors, phenotypes and genetics. Autism Res. 2009;2(6):293-311
    • (2009) Autism Res , vol.2 , Issue.6 , pp. 293-311
    • Jacob, S.1    Landeros-Weisenberger, A.2    Leckman, J.F.3
  • 19
    • 0029875873 scopus 로고    scopus 로고
    • Brief report: Psychopharmacology of autism spectrum disorders
    • DOI 10.1007/BF02172018
    • Lewis MH. Brief report: psychopharmacology of autism spectrum disorders. J Autism Dev Disord. 1996;26(2):231-235 (Pubitemid 26140734)
    • (1996) Journal of Autism and Developmental Disorders , vol.26 , Issue.2 , pp. 231-235
    • Lewis, M.H.1
  • 20
    • 44949149156 scopus 로고    scopus 로고
    • Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD)
    • CD001765
    • Soomro GM, Altman D, Rajagopal S, Oakley-Browne M. Selective serotonin re-uptake inhibitors (SSRIs) versus placebo for obsessive compulsive disorder (OCD). Cochrane Database Syst Rev. 2008;(1):CD001765
    • (2008) Cochrane Database Syst Rev , Issue.1
    • Soomro, G.M.1    Altman, D.2    Rajagopal, S.3    Oakley-Browne, M.4
  • 21
    • 0023887476 scopus 로고
    • An assessment of clinically useful measures of the consequences of treatment
    • Laupacis A, Sackett DL, Roberts RS. An assessment of clinically useful measures of the consequences of treatment. N Engl J Med. 1988;318(26):1728-1733
    • (1988) N Engl J Med , vol.318 , Issue.26 , pp. 1728-1733
    • Laupacis, A.1    Sackett, D.L.2    Roberts, R.S.3
  • 24
    • 84893391547 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD)
    • CD004677
    • Williams K, Wheeler DM, Silove N, Hazell P. Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). Cochrane Database Syst Rev. 2010;(8):CD004677
    • (2010) Cochrane Database Syst Rev , Issue.8
    • Williams, K.1    Wheeler, D.M.2    Silove, N.3    Hazell, P.4
  • 25
    • 40949152478 scopus 로고    scopus 로고
    • Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders
    • Available at
    • Mandell DS, Morales KH, Marcus SC, Stahmer AC, Doshi J, Polsky DE. Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics. 2008;121(3). Available at: www.pediatrics.org/ cgi/content/full/121/3/e441
    • (2008) Pediatrics , vol.121 , Issue.3
    • Mandell, D.S.1    Morales, K.H.2    Marcus, S.C.3    Stahmer, A.C.4    Doshi, J.5    Polsky, D.E.6
  • 27
    • 77549088002 scopus 로고    scopus 로고
    • Psychotropic medication use among children with autism spectrum disorders enrolled in a national registry, 2007-2008
    • Rosenberg RE, Mandell DS, Farmer JE, Law JK, Marvin AR, Law PA. Psychotropic medication use among children with autism spectrum disorders enrolled in a national registry, 2007-2008. J Autism Dev Disord. 2010;40(3):342-351
    • (2010) J Autism Dev Disord. , vol.40 , Issue.3 , pp. 342-351
    • Rosenberg, R.E.1    Mandell, D.S.2    Farmer, J.E.3    Law, J.K.4    Marvin, A.R.5    Law, P.A.6
  • 31
    • 0022003626 scopus 로고
    • The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects
    • Aman MG, Singh NN, Stewart AW, Field CJ. The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects. Am J Ment Defic. 1985;89(5):485-491 (Pubitemid 15104762)
    • (1985) American Journal of Mental Deficiency , vol.89 , Issue.5 , pp. 485-491
    • Aman, M.G.1    Singh, N.N.2    Stewart, A.W.3    Field, C.J.4
  • 32
    • 0028929172 scopus 로고
    • Assessing the quality of randomized controlled trials: An annotated bibliography of scales and checklists
    • Moher D, Jadad AR, Nichol G, Penman M, Tugwell P, Walsh S. Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists. Control Clin Trials. 1995;16(1):62-73
    • (1995) Control Clin Trials , vol.16 , Issue.1 , pp. 62-73
    • Moher, D.1    Jadad, A.R.2    Nichol, G.3    Penman, M.4    Tugwell, P.5    Walsh, S.6
  • 34
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-634 (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 37
    • 33746929827 scopus 로고    scopus 로고
    • Divalproex versus placebo for the prevention of irritability associated with fluoxetine treatment in autism spectrum disorder [11]
    • DOI 10.1097/01.jcp.0000227703.72117.bc, PII 0000471420060800000026
    • Anagnostou E, Esposito K, Soorya L, Chaplin W, Wasserman S, Hollander E. Divalproex versus placebo for the prevention of irritability associated with fluoxetine treatment in autism spectrum disorder. J Clin Psychopharmacol. 2006;26(4):444-446 (Pubitemid 44187659)
    • (2006) Journal of Clinical Psychopharmacology , vol.26 , Issue.4 , pp. 444-446
    • Anagnostou, E.1    Esposito, K.2    Soorya, L.3    Chaplin, W.4    Wasserman, S.5    Hollander, E.6
  • 38
    • 25844432049 scopus 로고    scopus 로고
    • Systematic review of randomized controlled trials of atypical antipsychotics and selective serotonin reuptake inhibitors for behavioural problems associated with pervasive developmental disorders
    • DOI 10.1177/0269881105056541
    • Dinca O, Paul M, Spencer NJ. Systematic review of randomized controlled trials of atypical antipsychotics and selective serotonin reuptake inhibitors for behavioural problems associated with pervasive developmental disorders. J Psychopharmacol. 2005;19(5):521-532 (Pubitemid 41392307)
    • (2005) Journal of Psychopharmacology , vol.19 , Issue.5 , pp. 521-532
    • Dinca, O.1    Paul, M.2    Spencer, N.J.3
  • 40
    • 21644459782 scopus 로고    scopus 로고
    • Lessons learnt in conducting a clinical drug trial in children with Asperger Syndrome
    • DOI 10.1111/j.1440-1665.2005.02183.x
    • Mathai J, Bourne A, Cranswick N. Lessons learnt in conducting a clinical drug trial in children with Asperger Syndrome. Australas Psychiatry. 2005;13(2):173-175 (Pubitemid 40936478)
    • (2005) Australasian Psychiatry , vol.13 , Issue.2 , pp. 173-175
    • Mathai, J.1    Bourne, A.2    Cranswick, N.3
  • 41
    • 0034931685 scopus 로고    scopus 로고
    • Clinical evaluation of treatment with fluvoxamine, a selective serotonin reuptake inhibitor, in children with autistic disorder
    • Fukuda T, Sugie H, Ito M, Sugie Y. Clinical evaluation of treatment with fluvoxamine, a selective serotonin reuptake inhibitor in children with autistic disorder [article in Japanese]. No To Hattatsu. 2001;33(4):314-318 (Pubitemid 32634472)
    • (2001) No To Hattatsu , vol.33 , Issue.4 , pp. 314-318
    • Fukuda, T.1    Sugie, H.2    Ito, M.3    Sugie, Y.4
  • 42
    • 84860582891 scopus 로고    scopus 로고
    • Neuropharm. Available at: Accessed April 23, 2011
    • Neuropharm. Study of fluoxetine in autism (SOFIA). Available at: http://clinicaltrials.gov/ct2/show/NCT00515320. Accessed April 23, 2011
    • Study of Fluoxetine in Autism (SOFIA)
  • 43
    • 84860582889 scopus 로고    scopus 로고
    • FDA Office of Orphan Products Development. Available from: Accessed April 23, 2011
    • FDA Office of Orphan Products Development. Study of fluoxetine in adults with autistic disorder. Available from: http://clinicaltrials.gov/ct2/show/ NCT00027404. Accessed April 23, 2011
    • Study of Fluoxetine in Adults with Autistic Disorder
  • 46
    • 0027158571 scopus 로고
    • A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder
    • Gordon CT, State RC, Nelson JE, Hamburger SD, Rapoport JL. A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder. Arch Gen Psychiatry. 1993;50(6):441-447 (Pubitemid 23169937)
    • (1993) Archives of General Psychiatry , vol.50 , Issue.6 , pp. 441-447
    • Gordon, C.T.1    State, R.C.2    Nelson, J.E.3    Hamburger, S.D.4    Rapoport, J.L.5
  • 48
    • 0034916963 scopus 로고    scopus 로고
    • Clomipramine versus haloperidol in the treatment of autistic disorder: A double-blind, placebo-controlled, crossover study
    • DOI 10.1097/00004714-200108000-00012
    • Remington G, Sloman L, Konstantareas M, Parker K, Gow R. Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. J Clin Psychopharmacol. 2001;21(4):440-444 (Pubitemid 32673034)
    • (2001) Journal of Clinical Psychopharmacology , vol.21 , Issue.4 , pp. 440-444
    • Remington, G.1    Sloman, L.2    Konstantareas, M.3    Parker, K.4    Gow, R.5
  • 49
    • 13944264748 scopus 로고    scopus 로고
    • A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism
    • DOI 10.1038/sj.npp.1300627
    • Hollander E, Phillips A, Chaplin W, et al. A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology. 2005;30(3):582-589 (Pubitemid 40271160)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.3 , pp. 582-589
    • Hollander, E.1    Phillips, A.2    Chaplin, W.3    Zagursky, K.4    Novotny, S.5    Wasserman, S.6    Iyengar, R.7
  • 50
    • 66449098701 scopus 로고    scopus 로고
    • Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: Citalopram ineffective in children with autism
    • STAART Psychopharmacology Network
    • King BH, Hollander E, Sikich L, et al STAART Psychopharmacology Network. Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism. Arch Gen Psychiatry. 2009;66(6):583-590
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.6 , pp. 583-590
    • King, B.H.1    Hollander, E.2    Sikich, L.3
  • 51
    • 0033934949 scopus 로고    scopus 로고
    • Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis
    • Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56(2):455-463 (Pubitemid 30422636)
    • (2000) Biometrics , vol.56 , Issue.2 , pp. 455-463
    • Duval, S.1    Tweedie, R.2
  • 52
    • 0033746434 scopus 로고    scopus 로고
    • Repetitive thoughts and behavior in pervasive developmental disorders: Treatment with serotonin reuptake inhibitors
    • McDougle CJ, Kresch LE, Posey DJ. Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors. J Autism Dev Disord. 2000;30(5):427-435
    • (2000) J Autism Dev Disord , vol.30 , Issue.5 , pp. 427-435
    • McDougle, C.J.1    Kresch, L.E.2    Posey, D.J.3
  • 53
    • 0033546995 scopus 로고    scopus 로고
    • What is meant by intention to treat analysis? Survey of published randomised controlled trials
    • Hollis S, Campbell F. What is meant by intention to treat analysis? Survey of published randomised controlled trials. BMJ. 1999;319(7211):670-674 (Pubitemid 29423954)
    • (1999) British Medical Journal , vol.319 , Issue.7211 , pp. 670-674
    • Hollis, S.1    Campbell, F.2
  • 54
    • 79959944023 scopus 로고    scopus 로고
    • Restricted and repetitive behaviors in autism spectrum disorders: A review of research in the last decade
    • Leekam SR, Prior MR, Uljarevic M. Restricted and repetitive behaviors in autism spectrum disorders: a review of research in the last decade. Psychol Bull. 2011;137(4):562-593
    • (2011) Psychol Bull , vol.137 , Issue.4 , pp. 562-593
    • Leekam, S.R.1    Prior, M.R.2    Uljarevic, M.3
  • 55
    • 38349049478 scopus 로고    scopus 로고
    • Selective publication of antidepressant trials and its influence on apparent efficacy
    • Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med. 2008;358(3):252-260
    • (2008) N Engl J Med , vol.358 , Issue.3 , pp. 252-260
    • Turner, E.H.1    Matthews, A.M.2    Linardatos, E.3    Tell, R.A.4    Rosenthal, R.5
  • 56
    • 1942468862 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors in childhood depression: Systematic review of published versus unpublished data
    • Whittington CJ, Kendall T, Fonagy P, Cottrell D, Cotgrove A, Boddington E. Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet. 2004;363(9418):1341-1345
    • (2004) Lancet , vol.363 , Issue.9418 , pp. 1341-1345
    • Whittington, C.J.1    Kendall, T.2    Fonagy, P.3    Cottrell, D.4    Cotgrove, A.5    Boddington, E.6
  • 57
    • 78650169395 scopus 로고    scopus 로고
    • Time-lag bias in trials of pediatric antidepressants: A systematic review and meta-analysis
    • Reyes MM, Panza KE, Martin A, Bloch MH. Time-lag bias in trials of pediatric antidepressants: a systematic review and meta-analysis. J Am Acad Child Adolesc Psychiatry. 2011;50(1):63-72
    • (2011) J Am Acad Child Adolesc Psychiatry , vol.50 , Issue.1 , pp. 63-72
    • Reyes, M.M.1    Panza, K.E.2    Martin, A.3    Bloch, M.H.4
  • 58
    • 33645754287 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors in autism: A review of efficacy and tolerability
    • Kolevzon A, Mathewson KA, Hollander E. Selective serotonin reuptake inhibitors in autism: a review of efficacy and tolerability. J Clin Psychiatry. 2006;67(3):407-414
    • (2006) J Clin Psychiatry , vol.67 , Issue.3 , pp. 407-414
    • Kolevzon, A.1    Mathewson, K.A.2    Hollander, E.3
  • 59
    • 84855661185 scopus 로고    scopus 로고
    • Despite law, fewer than one in eight completed studies of drugs and biologics are reported on time on ClinicalTrials.gov
    • Law MR, Kawasumi Y, Morgan SG. Despite law, fewer than one in eight completed studies of drugs and biologics are reported on time on ClinicalTrials.gov. Health Aff (Millwood). 2011;30(12):2338-2345
    • (2011) Health Aff (Millwood). , vol.30 , Issue.12 , pp. 2338-2345
    • Law, M.R.1    Kawasumi, Y.2    Morgan, S.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.