Nanofibrous collagen nerve conduits for spinal cord repair

Tissue Engineering - Part A

Volumn 18, Issue 9-10, 2012, Pages 1057-1066

  Liu, Ting ^a   Houle, John D ^b   Xu, Jinye ^c   Chan, Barbara P ^c   Chew, Sing Yian ^a  

^a Nanyang Technological University   (Singapore)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ENZYME INHIBITION; FIBERS; HYDROGELS; NANOFIBERS; NEURONS; RATS; REPAIR;

COLLAGEN NERVE CONDUITS; ELECTROSPUN NANOFIBERS; EXTRACELLULAR MATRICES; GLIAL FIBRILLARY ACIDIC PROTEINS; IMMUNOFLUORESCENT STAINING; SPINAL CORD INJURIES (SCI); TISSUE-ENGINEERED SCAFFOLDS; TOPOGRAPHICAL EFFECTS;

SCAFFOLDS (BIOLOGY);

RATTUS;

COLLAGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; TISSUE SCAFFOLD;

ANIMAL; ARTICLE; ASTROCYTE; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; METABOLISM; METHODOLOGY; NERVE REGENERATION; PHYSIOLOGY; RAT; SPINAL CORD INJURY; SPINAL GANGLION; TISSUE ENGINEERING;

ANIMALS; ASTROCYTES; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; GANGLIA, SPINAL; GLIAL FIBRILLARY ACIDIC PROTEIN; NERVE REGENERATION; RATS; SPINAL CORD INJURIES; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84860517621     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0430     Document Type: Article

References (54)

1. Willerth, S.M., and Sakiyama-Elbert, S.E. Approaches to neural tissue engineering using scaffolds for drug delivery. Adv Drug Deliver Rev 59, 325, 2007.
2. Fitch, M.T., Doller, C., Combs, C.K., Landreth, G.E., and Silver, J. Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma. J Neurosci 19, 8182, 1999.
3. Sliver J., and Miller, J.H. Regeneration beyond the glial scar. Nat Rev Neurosci 5, 146, 2004.
4. Grandpre, T., and Strittmatter, S.M. Nogo: A molecular determinant of axonal growth and regeneration. Neuroscientist 7, 377, 2001.
5. Busch, S.A., and Silver, J. The role of extracellular matrix in CNS regeneration. Curr Opin Neurobiol 17, 120, 2007.
6. Taylor, S.J., McDonald, J.W., and Sakiyama-Elbert, S.E. Controlled release of neurotrophin-3 from fibrin gels for spinal cord injury. J Control Release 98, 281, 2004.
7. Taylor, S.J., and Sakiyama-Elbert, S.E. Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model. J Control Release 116, 204, 2006.
8. Yoshii, S., Oka, M., Shima, M., Akagi, M., and Taniguchi, A. Bridging a spinal cord defect using collagen filament. Spine 28, 2346, 2003.
9. Yoshii, S., Ito, S., Shima, M., Taniguchi, A., and Akagi, M. Functional restoration of rabbit spinal cord using collagenfilament scaffold. J Tissue Eng Regen Med 3, 19, 2009.
10. Christopherson, G.T., Song, H., and Mao, H.Q. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials 30, 556, 2009.
11. Noriega, S.E., Hasanova, G.I., Schneider, M.J., Larsen, G.F., and Subramanian, A. Effect of fiber diameter on the spreading, proliferation and differentiation of chondrocytes on electrospun chitosan matrices. Cells Tissues Organs 2011 [Epub ahead of print]; DOI: 10.1159/000325144.
12. Kempf, M., Miyamura, Y., Liu, P.-Y., Chen, A.C.H., Nakamura, H., Shimizu, H., Tabata, Y., Kimble, R.M., and McMillan, J.R. A denatured collagen microfiber scaffold seeded with human fibroblasts and keratinocytes for skin grafting. Biomaterials 32, 4782, 2011.
13. Sell, S.A., Wolfe, P.S., Garg, K., McCool, J.M., Rodriguez, I.A., and Bowlin, G.L. The use of natural polymers in tissue engineering: a focus on electrospun extracellular matrix analogues. Polymers 2, 522, 2010.
14. Chew, S.Y., Wen, J., Yim, E.K.F., and Leong, K.W. Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules 6, 2017, 2005.
15. Chew, S.Y., Mi, R., Hoke, A., and Leong, K.W. Aligned protein-polymer composite fibers enhance nerve regeneration: a potential tissue-engineering platform. Adv Funct Mate 17, 1288, 2007.
16. Cao, H., Jiang, X., Chai, C., and Chew, S.Y. RNA interference by nanofiber-based siRNA delivery system. J Control Release 144, 203, 2011.
17. Rujitanaroj, P.-O., Wang, Y.-C., Wang, J., and Chew, S.Y. Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications. Biomaterials 32, 5915, 2011.
18. Gelain, F., Antonini, S.P., Cunha, C., Donega, M., Lowery, J., Taraballi, F., Cerri, G., Montagna, M., Baldissera, F. and Vescovi, A. Transplantation of nanostructured composite scaffolds results in the regeneration of chronically injured spinal cords. ACS Nano 5, 227, 2011.
19. Meiners, S., Ahmed, I., Ponery, A.S., Amor, N., Harris, S.L., Ayres, V., Fan, Y., Chen, Q., Delgado-Rivera, R., and Babu, A.N. Engineering electrospun nanofibrillar surfaces for spinal cord repair: a discussion. Polym Int 56, 1340, 2007.
20. Hurtado, A., Cregg, J.M., Wang, H.B., Wendell, D.F., Oudega, M., Gilbert, R.M., and McDonald, J.W. Robust CNS regeneration after complete spinal cord transection using aligned poly-l-lactic acid microfibers. Biomaterials 32, 6068, 2011.
21. Turner, D.C., Flier, L.A., and Carbonetto, S. Identification of a cell-surface protein involved in PC12 cell-substratum adhesion and neurite outgrowth on laminin and collagen. J Neurosci 9, 3287, 1989.
22. Condic, M.L. Adult neuronal regeneration induced by transgenic integrin expression. J Neurosci 21, 4782, 2001.
23. Liu, T., Teng, W.K., Chan, B.P., and Chew, S.Y. Photochemical crosslinked electrospun collagen nanofibers: synthesis, characterization and neural stem cell interactions. J Biomed Mater Res A 95A, 276, 2010.
24. Rajan, N., Habermehl, J., Cote, M.-F., Doillon, C.J., and Mantovani, D. Preparation of ready-to-use, storable and reconstituted type I collagen from rat tail tendon for tissue engineering applications. Nat Protoc 1, 2753, 2007.
25. Schwartz, J.P., and Wilson, D.J. Preparation and characterization of type 1 astrocytes cultured from adult rat cortex, cerebellum, and striatum. Glia 5, 75, 1992.
26. Yim, E.K.F., Pang, S.W., and Leong, K.W. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res 313, 1820, 2007.
27. Andersson, A.-S., Bäckhed, F., von Euler, A., Richter-Dahlfors, A., Sutherland, D., and Kasemo, B. Nanoscale features influence epithelial cell morphology and cytokine production. Biomaterials 24, 3427, 2003.
28. Miron-Mendoza, M., Seemann, J., and Grinnell, F. The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices. Biomaterials 31, 6425, 2010.
29. Liu, W., Shafit-Zagardo, B., Aquino, D.A., Zhao, M.-L., Dickson, D.W., Brosnan, C.F., and Lee, S.C. Cytoskeletal alterations in human fetal astrocytes induced by interleukin-1b. J Neurochem 63, 1625, 1994.
30. Dieterich, D.C., Hodas, J.L., Gouzer, G., Shadrin, I.Y., Ngo, J.T., Triller, A., Tirrel, D.A., and Schuman, E.M. In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nat Neurosci 13, 897, 2010.
31. Johnson, P.J., Parker, S.R., and Sakiyama-Elbert, S.E. Fibrinbased tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury. J Biomed Mater Res A 92, 152, 2010.
32. Nomura, H., Katayama, Y.M., Shoichet, M.S., and Tator, C.H. Complete spinal cord transection treated by implantation of a reinforced synthetic hydrogel channel results in syringomyelia and caudal migration of the rostral stump. Neurosurgery 59, 183, 2006.
33. Tsai, E.C., Dalton, P.D., Shoichet, M.S., and Tator, C.H. Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. Biomaterials 27, 519, 2006.
34. Berrier, A.L., and Yamada, K.M. Cell-matrix adhesion. J Cell Physiol 213, 565, 2007.
35. Green, J.A., and Yamada, K.M. Three-dimensional microenvironments modulate fibroblast signaling responses. Adv Drug Deliver Rev 59, 1293, 2007.
36. Delgado-Rivera, R., Harris, S.L., Ahmed, I., Babu, A.N., Patel, R.P., Ayres, V., Flowers, D., and Meiners, S. Increased FGF-2 secretion and ability to support neurite outgrowth by astrocytes cultured on polyamide nanofibrillar matrices. Matrix Biol 28, 137, 2009.
37. Chew, S.Y., Mi, R., Hoke, A., and Leong, K.W. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 29, 653, 2008.
38. Jiang, X., Lim, S.H., Mao, H.-Q., and Chew, S.Y. Current applications and future perspectives of artificial nerve conduits. Exp Neurol 223, 86, 2010.
39. Schnell, E., Klinkhammer, K., Balzer, S., Brook, G., Klee, D., Dalton, P., and Mey, J. Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-[epsilon]-caprolactone and a collagen/poly- [epsilon]-caprolactone blend. Biomaterials 28, 3012, 2007.
40. Cao, H., Liu, T., and Chew, S.Y. The application of nanofibrous scaffolds in neural tissue engineering. Adv Drug Deliver Rev 61, 1055, 2009.
41. McKeon, R.J., Schreiber, R.C., Rudge, J.S., and Silver, J. Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J Neurosci 11, 3398, 1991.
42. Ridet, J.-L., Privat, A., and Sudarshan, K.M. Reactive astrocytes, their roles in CNS injury, and repair mechanisms. Adv Str Bio 6, 147, 2000.
43. Ferraguti, F., Corti, C., Valerio, E., Mion, S., and Xuereb, J. Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5. Exp Brain Res 137, 1, 2001.
44. Gerardo-Nava, J., Fuhrmann, T., Klinkhammer, K., Seiler, N., Mey, J., Klee, D., Moller, M., Dalton, P.D., and Brook, G.A. Human neural cell interactions with orientated electrospun nanofibers in vitro. Nanomedicine 4, 11, 2009.
45. Baiguera, S., Gaudio, C.D., Fioravanzo, L., Bianco, A., Grigioni, M., and Folin, M. In vitro astrocytes and cerebral endothelial cell response to electropun poly(e-caprolactone) mats of different architecture. J Mate Sci Mater 21, 1353, 2010.
46. East, E., de Oliveira, D.B., Golding, J.P., and Phillips, J.B. Alignment of astrocytes increases neuronal growth in threedimensional collagen gels and is maintained following plastic compression to form a spinal cord repair conduit. Tissue Eng A 16, 3173, 2010.
47. Discher, D.E., Janmey, P., and Wang, Y.-L. Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139, 2005.
48. Georges, P.C., Miller, W.J., Meaney, D.F., Sawyer, E.S., and Janmey, P.A. Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures. Biophys J 90, 3012, 2006.
49. Stokols, S., and Tuszynski, M.H. Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury. Biomaterials 27, 443, 2006.
50. Cao, H., McHugh, K., Chew, S.Y., and Anderson, J.M. The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction. J Biomed Mater Res A 93, 1151, 2010.
51. Moses, O., Vitrial, D., Aboodi, G., Sculean, A., Tal, H., Kozlovsky, A., Artzi, Z., Weinreb, M., and Nemcovsky, C.E. Biodegradation of three different collagen membranes in the rat calvarium: a comparative study. J Periodontol 79, 905, 2008.
52. Bölgen, N., Mencelog? lu, Y.Z., Acatay, K., Vargel, I., and Pikin, E. In vitro and in vivo degradation of non-woven materials made of poly(e-caprolactone) nanofibers prepared by electrospinning under different conditions. J Biomate Sci Polymer Ed 16, 1537, 2005.
53. Hsu, J.-Y.C., and Xu, X.-M. Early profiles of axonal growth and astroglial response after spinal cord hemisection and implantation of Schwann cell-seeded guidance channels in adult rats. J Neurosci Res 82, 472, 2005.
54. Wang, H.B., Mullins, M.E., Cregg, J.M., McCarthy, C.W., and Gilbert, R.J. Varying the diameter of aligned electrospun fibers alters neurite outgrowth and Schwann cell migration. Acta Biomater 6, 2970, 2010.