Unusual D:B-friedobaccharane and oxygenated friedelane-type triterpenoids from Salvadorean Celastraceae species

Phytochemistry Letters

Volumn 5, Issue 2, 2012, Pages 244-248

  Núñez, Marvin J ^a,b   Ardiles, Alejandro E ^a   Martínez, Morena L ^b   Torres Romero, David ^b   Jiménez, Ignacio A ^a   Bazzocchi, Isabel L ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b University of El Salvador   (El Salvador)

Author keywords

Cassine xylocarpa; Celastraceae; Celastrus vulcanicola; D:A friedooleanane; D:B friedobaccharane

Indexed keywords

CASSINOLIDE; FRIEDELANE; FRIEDOBACCHARANE; LEONATRIOL; LEONATRIOLONE; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; BARK; BIOGENESIS; CASSINE XYLOCARPA; CELASTRACEAE; CELASTRUS VULCANICOLA; DEUTERON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; EL SALVADOR; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY;

CASSINE XYLOCARPA; CELASTRACEAE; CELASTRUS;

EID: 84860512305     PISSN: 18743900     EISSN: 18767486     Source Type: Journal    
DOI: 10.1016/j.phytol.2012.01.004     Document Type: Article

References (14)

1. N. Alvarenga, and E.A. Ferro Bioactive triterpenes and related compounds from Celastraceae Atta-ur-Rahman Studies in Natural Products Chemistry. Part M vol. 33 2006 Elsevier BV Amsterdam 239 307
2. H. Duan, K. Kawazoe, M. Bando, M. Kido, and Y. Takaishi Di- and triterpenoids from Tripterygium hypoglaucum Phytochemistry 46 1997 535 543
3. A.G. González, I.L. Bazzocchi, L.M. Moujir, and I.A. Jiménez Ethobotanical uses of Celastraceae bioactive metabolites Atta-ur-Rahman Studies in Natural Products Chemistry. Part D vol. 23 2000 Elsevier BV Amsterdam 649 738
4. S. Lodeiro, Q. Xiong, W.K. Wilson, M.D. Kolesnikova, C.S. Onak, and S.P.T. Matsuda An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis J. Am. Chem. Soc. 129 2007 11213 11222
5. R. Niero, S.D.A. Faloni, and V.F. Cechinel A review of the ethnopharmacology, phytochemistry and pharmacology of plants of the Maytenus genus Curr. Pharm. Des. 17 2011 1851 1871
6. M.J. Núñez, M.R. López, I.A. Jiménez, L.M. Moujir, A.G. Ravelo, and I.L. Bazzocchi First examples of tetrachyclic triterpenoids with a D:B-friedobacchrane skeleton. A tentative biosynthetic route Tetrahedr. Lett. 45 2004 7367 7370
7. B.M. Reyes, M.T. Ramírez-Apan, R.A. Toscano, and G. Delgado Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes J. Nat. Prod. 73 2010 1839 1845
8. J.M. Seco, E. Quiñoa, and R. Riguera The assignment of absolute configuration by NMR Chem. Rev. 104 2004 17 117
9. D. Torres-Romero, B. King-Díaz, I.A. Jiménez, B. Lotina-Hennsen, and I.L. Bazzocchi Sesquiterpenes from Celastrus vulcanicola as photosynthetic inhibitors J. Nat. Prod. 71 2008 1331 1335
10. D. Torres-Romero, F. Muñoz-Martínez, I.A. Jiménez, S. Castanys, F. Gamarro, and I.L. Bazzocchi Novel dihydro-β-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance Org. Biomol. Chem. 7 2009 5166 5172
11. D. Torres-Romero, B. King-Díaz, R.J. Strasser, I.A. Jiménez, B. Lotina-Hennsen, and I.L. Bazzocchi Friedelane triterpenes from Celastrus vulcanicola as photosynthetic inhibitors J. Agric. Food Chem. 58 2010 10847 10854
12. D. Torres-Romero, I.A. Jiménez, R. Rojas, R.H. Gilman, M. López, and I.L. Bazzocchi Dihydro-β-agarofuran sesquiterpenes isolated from Celastrus vulcanicola as potential anti-Mycobacterium tuberculosis multidrug-resistant agents Bioorg. Med. Chem. 19 2011 2182 2189
13. W. Zhang, D. Pan, L. Zhang, and Y. Shao Triterpenoids of Tripterygium wilfordii Hook-F Yaoxue Xuebao 21 1986 592 598
14. Y. Zhang, S. Nakamura, T. Wang, H. Matsuda, and M. Yoshikawa The absolute stereostructures of three rare D:B-friedobaccharane skeleton triterpenes from the leaves of Salacia chinensis Tetrahedron 64 2008 7347 7352