Preproendothelin-1 expression is negatively regulated by IFNγ during hepatic stellate cell activation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 302, Issue 9, 2012, Pages

  Li, Tianxia ^a   Shi, Zengdun ^a   Rockey, Don C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cytokine; Gene expression; Liver; Signal pathway

Indexed keywords

COLLAGEN TYPE 1; GAMMA INTERFERON; MESSENGER RNA; PREPROENDOTHELIN 1; PROTEIN C JUN; SMAD3 PROTEIN; SMOOTH MUSCLE ACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING KINETICS; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROGENESIS; IMMUNOBLOTTING; IMMUNOMODULATION; IN VIVO STUDY; INHIBITION KINETICS; LIVER INJURY; MALE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WOUND HEALING;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIN-1; HEPATIC STELLATE CELLS; INTERFERON-GAMMA; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84860512255     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00359.2011     Document Type: Article

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