Spatiotemporally controlled cardiac conduction block using high-frequency electrical stimulation

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Dura, Burak ^a,b   Kovacs, Gregory T A ^a   Giovangrandi, Laurent ^a  

^a Stanford University   (United States)

^b USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; POTASSIUM CHANNEL; SODIUM CHANNEL;

ALTERNATING CURRENT; ANIMAL CELL; ARTICLE; CELL CULTURE; CHANNEL GATING; COMPUTER SIMULATION; CONTROLLED STUDY; ELECTRODE; ELECTROSTIMULATION; EXPERIMENTAL MODEL; HEART ARRHYTHMIA; HEART BEAT; HEART CONDUCTION; HEART EXCITATION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HIGH FREQUENCY ELECTROSTIMULATION; MICROELECTRODE; MOUSE; NONHUMAN; STIMULUS RESPONSE; TISSUE CULTURE; WAVEFORM; ACTION POTENTIAL; ANIMAL; CELL LINE; CYTOLOGY; EXTRACELLULAR SPACE; HEART MUSCLE CONDUCTION SYSTEM; INSTRUMENTATION; METABOLISM; METHODOLOGY; TIME;

ACTION POTENTIALS; ANIMALS; CELL LINE; ELECTRIC STIMULATION; ELECTRODES; EXTRACELLULAR SPACE; HEART CONDUCTION SYSTEM; MICE; MYOCYTES, CARDIAC; TIME FACTORS;

EID: 84860491261     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036217     Document Type: Article

References (36)

1. Basser PJ, Roth BJ, (2000) New currents in electrical stimulation of excitable tissues. Annu Rev Biomed Eng 2: 377-397.
2. Fromer M, Shenasa M, (1992) Ultrarapid subthreshold stimulation for termination of atrioventricular node reentrant tachycardia. J Am Coll Cardiol 20: 879-883.
3. Paya R, Chorro FJ, Sanchis J, Alberola A, Dalli E, et al. (1991) Changes in canine ventricular refractoriness induced by trains of subthreshold high-frequency stimuli. J Electrocardiol 24: 63-69.
4. Prystowsky EN, Zipes DP, (1983) Inhibition in the human heart. Circulation 68: 707-713.
5. Windle JR, Miles WM, Zipes DP, Prystowsky EN, (1986) Subthreshold conditioning stimuli prolong human ventricular refractoriness. Am J Cardiol 57: 381-386.
6. Swedlow CD, Liem LB, Franz MR, (1987) Summation and inhibition by ultrarapid train pacing in the human ventricle. Circulation 76: 1101-1109.
7. Meunier JM, Trayanova NA, Gray RA, (1999) Sinusoidal stimulation of myocardial tissue: effects on single cells. J Cardiovasc Electrophysiol 10: 1619-1630.
8. Meunier JM, Trayanova NA, Gray RA, (2001) Entrainment by an extracellular AC stimulus in a computational model of cardiac tissue. J Cardiovasc Electrophysiol 12: 1176-1184.
9. Tandri H, Weinberg SH, Chang KC, Zhu R, Trayanova NA, et al. (2011) Reversible Cardiac Conduction Block and Defibrillation with High-Frequency Electric Field. Sci Transl Med 3: 102ra96.
10. Fisher JD, Ostrow E, Kim SG, Matos JA, (1983) Ultrarapid single-capture train stimulation for termination of ventricular tachycardia. Am J Cardiol 51: 1334-1338.
11. Gray RA, Foster E, Jalife J, (1996) Entrainment of the intact ventricles using field stimulation. PACE 19: 666.
12. Antoni H, Toppler J, Krause H, (1970) Polarization effects of sinusoidal 50-cycle alternating current on membrane potential of mammalian cardiac fibres. Pflugers Arch 314: 274-291.
13. Prevost J, Batelli F, (1899) Death by electric currents (alternating current). C R Acad Sci 128: 668.
14. Malkin RA, Hoffmeister BK, (2001) Mechanisms by which AC leakage currents cause complete hemodynamic collapse without inducing fibrillation. J Cardiovasc Electrophysiol 12: 1154-1161.
15. Vigmond EJ, Trayanova NA, Malkin RA, (2001) Excitation of a cardiac muscle fiber by extracellularly applied sinusoidal current. J Cardiovasc Electrophysiol 12: 1145-1153.
16. Malkin RA, Curry AD, (2003) Frequency dependence of the cardiac threshold to alternating current between 10 Hz and 160 Hz. Med Biol Eng Comput 41: 640-645.
17. Nygren A, Fiset C, Firek L, Clark JW, Lindblad DS, Clark RB, et al. (1998) Mathematical model of an adult human atrial cell: the role of K+ currents in repolarization. Circ Res 82: 63-81.
18. Shenasa M, Cardinal R, Kus T, Savard P, Fromer M, et al. (1988) Termination of sustained ventricular tachycardia by ultrarapid subthreshold stimulation in humans. Circulation 78: 1135-1143.
19. Willems S, Weiss C, Shenasa M, Ventura R, Hoffmann M, et al. (2001) Optimized mapping of slow pathway ablation guided by subthreshold stimulation: a randomized prospective study in patients with recurrent atrioventricular nodal re-entrant tachycardia. J Am Coll Cardiol 37: 1645-1650.
20. Dura B, Chen MQ, Inan OT, Kovacs GTA, Giovangrandi L, (2012) High-frequency electrical stimulation of cardiac cells and application to artifact reduction. IEEE Trans Biomed Eng doi:10.1109/TBME.2012.2188136.
21. Schoen I, Fromherz P, (2008) Extracellular stimulation of mammalian neurons through repetitive activation of Na+ channels by weak capacitive currents on a silicon chip. J Neurophysiol 100: 346-357.
22. Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K, (2005) Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 8: 1263-1268.
23. Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, et al. (2007) Multimodal fast optical interrogation of neural circuitry. Nature 446: 633-639.
24. Arrenberg AB, Stainier DY, Baier H, Huisken J, (2010) Optogenetic control of cardiac function. Science 330: 971-974.
25. Katz B, (1939) Nerve excitation by high-frequency alternating current. J Phyiol 96: 202-224.
26. Bromm B, Simon R, (1971) Inward rectification in frog skeletal muscle membrane during alternating current stimulation. Pflügers Arch 329: 155-169.
27. Antoni H, Töppler J, Krause H, (1970) Polarization effects of sinusoidal 50-cycle alternating current on membrane potential of mammalian cardiac fibres. Pflügers Arch 814: 274-291.
28. Thomas SP, Bircher-Lehmann L, Thomas SA, Zhuang J, Saffitz JE, et al. (2000) Synthetic strands of neonatal mouse cardiac myocytes: structural and electrophysiological properties. Circ Res 87: 467-473.
29. González H, Nagai Y, Bub G, Glass L, Shrier A, (2003) Reentrant waves in a ring of embryonic chick ventricular cells imaged with a Ca2+ sensitive dye. Biosystems 71: 71-80.
30. Vinet A, Roberge FA, (1994) The dynamics of sustained reentry in a ring model of cardiac tissue. Ann Biomed Eng 22: 568-591.
31. Chorro FJ, Sanchis J, Lopez-Merino V, Burguera M, Martinez-Mas ML, et al. (1994) The influence of different electrode configurations on the inhibitory effect of subthreshold high-frequency stimuli. Eur Heart J 15: 1681-1688.
32. Whittington RH, (2006) Real-time control of electrical stimulation: a novel tool for compound screening and electrophysiologic analysis PhD thesis, Stanford University, Stanford, CA.
33. Gilchrist KH, Barker VN, Fletcher LE, DeBusschere BD, Ghanouni P, et al. (2001) General purpose, field-portable cell-based biosensor platform. Biosens Bioelectron 16: 557-564.
34. Claycomb WC, Lanson NA Jr, Stallworth BS, Egeland DB, Delcarpio JB, et al. (1998) HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci USA 95: 2979-2984.
35. Sartiani L, Bochet P, Cerbai E, Mugelli A, Fischmeister R, (2002) Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes. J Physiol 545: 81-92.
36. White SM, Constantin PE, Claycomb WC, (2004) Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function. Am J Physiol Heart Circ Physiol 286: H823-829.