Practical access to four stereoisomers of naftidrofuryl and their binding affinity towards 5-hydroxytryptamine 2A receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 10, 2012, Pages 3441-3444

  Hao, Jia ^a,b   Chen, Bo ^a   Yao, Yiwu ^a   Hossain, Murad ^c   Nagatomo, Takafumi ^c   Yao, Hequan ^a   Kong, Lingyi ^a   Sun, Hongbin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

Author keywords

5 HT 2A receptor; Configuration; Inhibitors; Naftidrofuryl stereoisomers; Resolution

Indexed keywords

NAFTIDROFURYL; NAFTIDROFURYL OXALATE; SEROTONIN 2A RECEPTOR;

ARTICLE; BINDING COMPETITION; BIOASSAY; DIASTEREOISOMER; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; LIGAND BINDING; QUANTUM YIELD; RECEPTOR AFFINITY; STEREOCHEMISTRY; STEREOISOMERISM;

BIOLOGICAL ASSAY; NAFRONYL; RECEPTOR, SEROTONIN, 5-HT2A; STEREOISOMERISM;

EID: 84860489551     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.03.093     Document Type: Article

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