DNA vaccine-generated duck polyclonal antibodies as a postexposure prophylactic to prevent hantavirus pulmonary syndrome (HPS)

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Brocato, Rebecca ^a   Josleyn, Matthew ^a   Ballantyne, John ^b   Vial, Pablo ^c   Hooper, Jay W ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b Aldevron LLC   (United States)

^c UNIVERSIDAD DEL DESARROLLO   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; FRESH FROZEN PLASMA; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN Y; NEUTRALIZING ANTIBODY; POLYCLONAL ANTIBODY; IMMUNOGLOBULIN G; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG PURIFICATION; DRUG SCREENING; DRUG SYNTHESIS; DUCK; FEMALE; HANTAVIRUS PULMONARY SYNDROME; IN VITRO STUDY; IN VIVO STUDY; INFECTION PREVENTION; LOW DRUG DOSE; NONHUMAN; POST EXPOSURE PROPHYLAXIS; PROVOCATION TEST; VIRUS NEUTRALIZATION; ANIMAL; BIOAVAILABILITY; BIOSYNTHESIS; HAMSTER; HANTAVIRUS; HUMAN; IMMUNOLOGY; PASSIVE IMMUNIZATION; PLASMA; SERODIAGNOSIS; SYRIAN HAMSTER; TITRIMETRY; VIROLOGY;

ANAS; ANAS PLATYRHYNCHOS; ANDES VIRUS; CRICETINAE; HANTAVIRUS; MESOCRICETUS AURATUS;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; BIOLOGICAL AVAILABILITY; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DUCKS; FEMALE; HANTAVIRUS; HANTAVIRUS PULMONARY SYNDROME; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; MESOCRICETUS; NEUTRALIZATION TESTS; PLASMA; TITRIMETRY; VACCINES, DNA;

EID: 84860487754     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035996     Document Type: Article

References (39)

1. Padula PJ, Colavecchia SB, Martinez VP, Gonzalez Della Valle MO, Edelstein A, et al. (2000) Genetic diversity, distribution, and serological features of hantavirus infection in five countries in South America. J Clin Microbiol 38: 3029-3035.
2. Martinez VP, Bellomo CM, Cacace ML, Suarez P, Bogni L, et al. (2010) Hantavirus pulmonary syndrome in Argentina, 1995-2008. Emerg Infect Dis 16: 1853-1860.
3. Health CMo (2011) Epidemiologic report of hantaviruses in Chile. Santiago, Chile.
4. Figueiredo LT, Moreli ML, de-Sousa RL, Borges AA, de-Figueiredo GG, et al. (2009) Hantavirus pulmonary syndrome, central plateau, southeastern, and southern Brazil. Emerg Infect Dis 15: 561-567.
5. Martinez VP, Bellomo C, San Juan J, Pinna D, Forlenza R, et al. (2005) Person-to-person transmission of Andes virus. Emerg Infect Dis 11: 1848-1853.
6. Padula PJ, Edelstein A, Miguel SD, Lopez NM, Rossi CM, et al. (1998) Hantavirus pulmonary syndrome outbreak in Argentina: molecular evidence for person-to-person transmission of Andes virus. Virology 241: 323-330.
7. Hammerbeck CD, Hooper JW, (2010) Hantavirus Vaccines. In: Levine MM, editors. New Generation Vaccines New York informa healthcare pp. 905-913.
8. St Jeor SC, (2004) Three-week incubation period for hantavirus infection. Pediatr Infect Dis J 23: 974-975.
9. Vial PA, Valdivieso F, Mertz G, Castillo C, Belmar E, et al. (2006) Incubation period of hantavirus cardiopulmonary syndrome. Emerg Infect Dis 12: 1271-1273.
10. Young JC, Hansen GR, Graves TK, Deasy MP, Humphreys JG, et al. (2000) The incubation period of hantavirus pulmonary syndrome. Am J Trop Med Hyg 62: 714-717.
11. Hooper JW, Custer DM, Thompson E, Schmaljohn CS, (2001) DNA vaccination with the Hantaan virus M gene protects Hamsters against three of four HFRS hantaviruses and elicits a high-titer neutralizing antibody response in Rhesus monkeys. J Virol 75: 8469-8477.
12. Campen MJ, Milazzo ML, Fulhorst CF, Obot Akata CJ, Koster F, (2006) Characterization of shock in a hamster model of hantavirus infection. Virology 356: 45-49.
13. Wahl-Jensen V, Chapman J, Asher L, Fisher R, Zimmerman M, et al. (2007) Temporal analysis of Andes virus and Sin Nombre virus infections of Syrian hamsters. J Virol 81: 7449-7462.
14. Custer DM, Thompson E, Schmaljohn CS, Ksiazek TG, Hooper JW, (2003) Active and passive vaccination against hantavirus pulmonary syndrome with Andes virus M genome segment-based DNA vaccine. J Virol 77: 9894-9905.
15. Safronetz D, Hegde NR, Ebihara H, Denton M, Kobinger GP, et al. (2009) Adenovirus vectors expressing hantavirus proteins protect hamsters against lethal challenge with andes virus. J Virol 83: 7285-7295.
16. Hooper JW, Ferro AM, Wahl-Jensen V, (2008) Immune serum produced by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. J Virol 82: 1332-1338.
17. Enria DA, Briggiler AM, Fernandez NJ, Levis SC, Maiztegui JI, (1984) Importance of dose of neutralising antibodies in treatment of Argentine haemorrhagic fever with immune plasma. Lancet 2: 255-256.
18. Maiztegui JI, Fernandez NJ, de Damilano AJ, (1979) Efficacy of immune plasma in treatment of Argentine haemorrhagic fever and association between treatment and a late neurological syndrome. Lancet 2: 1216-1217.
19. Lundquist AL, Chari RS, Wood JH, Miller GG, Schaefer HM, et al. (2007) Serum sickness following rabbit antithymocyte-globulin induction in a liver transplan recipient: case report and literature review. Liver Transplantation 13: 647-650.
20. Humphrey BD, Calvert CC, Klasing KC, (2004) The ratio of full length IgY to truncated IgY in immune complexes affects macrophage phagocytosis and the acute phase response of mallard ducks (Anas platyrhynchos). Dev Comp Immunol 28: 665-672.
21. Lundqvist ML, Middleton DL, Radford C, Warr GW, Magor KE, (2006) Immunoglobulins of the non-galliform birds: antibody expression and repertoire in the duck. Dev Comp Immunol 30: 93-100.
22. Grey HM, (1967) Duck immunoglobulins. II. Biologic and immunochemical studies. J Immunol 98: 820-826.
23. Chiou VY, (2008) The development of IgY(DeltaFc) antibody based neuro toxin antivenoms and the study on their neutralization efficacies. Clin Toxicol (Phila) 46: 539-544.
24. Cova L, (2005) DNA-designed avian IgY antibodies: novel tools for research, diagnostics and therapy. J Clin Virol 34 (Suppl 1): S70-74.
25. Rollier C, Charollois C, Jamard C, Trepo C, Cova L, (2000) Maternally transferred antibodies from DNA-immunized avians protect offspring against hepadnavirus infection. J Virol 74: 4908-4911.
26. Nguyen HH, Tumpey TM, Park HJ, Byun YH, Tran LD, et al. (2010) Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice. PLoS One 5: e10152.
27. Hooper JW, Larsen T, Custer DM, Schmaljohn CS, (2001) A lethal disease model for hantavirus pulmonary syndrome. Virology 289: 6-14.
28. Hooper JW, Kamrud KI, Elgh F, Custer D, Schmaljohn CS, (1999) DNA vaccination with hantavirus M segment elicits neutralizing antibodies and protects against seoul virus infection. Virology 255: 269-278.
29. FDA (2010) Approved Products: Immune Globulins.
30. Baur X, Chen Z, Rozynek P, Duser M, Raulf-Heimsoth M, (1995) Cross-reacting IgE antibodies recognizing latex allergens, including Hev b 1, as well as papain. Allergy 50: 604-609.
31. Quarre JP, Lecomte J, Lauwers D, Gilbert P, Thiriaux J, (1995) Allergy to latex and papain. J Allergy Clin Immunol 95: 922.
32. Casadevall A, (2002) Antibodies for defense against biological attack. Nat Biotechnol 20: 114.
33. de Almeida CM, da Silva CL, Couto HP, Escocard Rde C, da Rocha DG, et al. (2008) Development of process to produce polyvalent IgY antibodies anti-African snake venom. Toxicon 52: 293-301.
34. Ibrahim el SM, Rahman AK, Isoda R, Umeda K, Van Sa N, et al. (2008) In vitro and in vivo effectiveness of egg yolk antibody against Candida albicans (anti-CA IgY). Vaccine 26: 2073-2080.
35. Meenatchisundaram S, Parameswari G, Michael A, Ramalingam S, (2008) Neutralization of the pharmacological effects of Cobra and Krait venoms by chicken egg yolk antibodies. Toxicon 52: 221-227.
36. Abouzid K, Ndeboko B, Durantel S, Jamard C, Zoulim F, et al. (2006) Genetic vaccination for production of DNA-designed antibodies specific to Hepadnavirus envelope proteins. Vaccine 24: 4615-4617.
37. Warr GW, Magor KE, Higgins DA, (1995) IgY: clues to the origins of modern antibodies. Immunol Today 16: 392-398.
38. Safronetz D, Zivcec M, LaCasse R, Feldmann F, Rosenke R, et al. (2011) Pathogenesis and host response in Syrian hamsters following intranasal infection with Andes virus. PLoS Pathogens 7: e1002426.
39. Rollier C, Charollois C, Jamard C, Trepo C, Cova L, (2000) Early life humoral response of ducks to DNA immunization against hepadnavirus large envelope protein. Vaccine 18: 3091-3096.