메뉴 건너뛰기




Volumn 25, Issue 5, 2012, Pages 731-739

KRAS genotyping in rectal adenocarcinoma specimens with low tumor cellularity after neoadjuvant treatment

Author keywords

KRAS; mutation; neoadjuvant treatment; rectal cancer

Indexed keywords

CAPECITABINE; OXALIPLATIN;

EID: 84860463235     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2011.210     Document Type: Article
Times cited : (31)

References (48)
  • 1
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-1634.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 4
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008;359:1757-1765.
    • (2008) N Engl J Med , vol.359 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 6
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • Lievre A, Bachet JB, Le Corre D, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 2006;66:3992-3995.
    • (2006) Cancer Res , vol.66 , pp. 3992-3995
    • Lievre, A.1    Bachet, J.B.2    Le Corre, D.3
  • 8
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 2009;27:2091-2096.
    • (2009) J Clin Oncol , vol.27 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3
  • 9
    • 79952698311 scopus 로고    scopus 로고
    • External quality assessment for KRAS testing is needed: Setup of a European program and report of the first joined regional quality assessment rounds
    • Bellon E, Ligtenberg MJ, Tejpar S, et al. External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds. Oncologist 2011;16:467-478.
    • (2011) Oncologist , vol.16 , pp. 467-478
    • Bellon, E.1    Ligtenberg, M.J.2    Tejpar, S.3
  • 10
    • 68849120567 scopus 로고    scopus 로고
    • KRAS mutation testing in colorectal cancer
    • Plesec TP, Hunt JL. KRAS mutation testing in colorectal cancer. Adv Anat Pathol 2009;16:196-203.
    • (2009) Adv Anat Pathol , vol.16 , pp. 196-203
    • Plesec, T.P.1    Hunt, J.L.2
  • 11
    • 54249098184 scopus 로고    scopus 로고
    • KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: Proposal for an European quality assurance program
    • van Krieken JH, Jung A, Kirchner T, et al. KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. Virchows Arch 2008;453:417-431.
    • (2008) Virchows Arch , vol.453 , pp. 417-431
    • Van Krieken, J.H.1    Jung, A.2    Kirchner, T.3
  • 12
    • 61449154484 scopus 로고    scopus 로고
    • KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: Practical application of patient selection
    • Jimeno A, Messersmith WA, Hirsch FR, et al. KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection. J Clin Oncol 2009; 27:1130-1136.
    • (2009) J Clin Oncol , vol.27 , pp. 1130-1136
    • Jimeno, A.1    Messersmith, W.A.2    Hirsch, F.R.3
  • 13
    • 77951892843 scopus 로고    scopus 로고
    • The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: A comparison between direct sequencing and real-time PCR
    • Kobunai T, Watanabe T, Yamamoto Y, Eshima K. The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: a comparison between direct sequencing and real-time PCR. Biochem Biophys Res Commun 2010;395:158-162.
    • (2010) Biochem Biophys Res Commun , vol.395 , pp. 158-162
    • Kobunai, T.1    Watanabe, T.2    Yamamoto, Y.3    Eshima, K.4
  • 14
    • 77950846704 scopus 로고    scopus 로고
    • A comparability study of 5 commercial KRAS tests
    • Oliner K, Juan T, Suggs S, et al. A comparability study of 5 commercial KRAS tests. Diagn Pathol 2010;16:5-23.
    • (2010) Diagn Pathol , vol.16 , pp. 5-23
    • Oliner, K.1    Juan, T.2    Suggs, S.3
  • 15
    • 77349084430 scopus 로고    scopus 로고
    • Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues
    • van Eijk R, van Puijenbroek M, Chhatta AR, et al. Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues. J Mol Diagn 2010;12:27-34.
    • (2010) J Mol Diagn , vol.12 , pp. 27-34
    • Van Eijk, R.1    Van Puijenbroek, M.2    Chhatta, A.R.3
  • 16
    • 77951725120 scopus 로고    scopus 로고
    • A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: A morphology-based approach in colorectal carcinoma
    • Angulo B, Garcia-Garcia E, Martinez R, et al. A commercial real-time PCR kit provides greater sensitivity than direct sequencing to detect KRAS mutations: a morphology-based approach in colorectal carcinoma. J Mol Diagn 2010;12:292-299.
    • (2010) J Mol Diagn , vol.12 , pp. 292-299
    • Angulo, B.1    Garcia-Garcia, E.2    Martinez, R.3
  • 18
    • 77957129235 scopus 로고    scopus 로고
    • High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue
    • Tol J, Dijkstra JR, Vink-Borger ME, et al. High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue. J Cell Mol Med 2009;14:2122-2131.
    • (2009) J Cell Mol Med , vol.14 , pp. 2122-2131
    • Tol, J.1    Dijkstra, J.R.2    Vink-Borger, M.E.3
  • 19
    • 79952741808 scopus 로고    scopus 로고
    • KRAS mutation testing in patients with metastatic colorectal carcinoma: An 18-month experience emphasizing the risk of false-negative results
    • SUPPL. abstr 3572
    • Bibeau F, Frugier H, Crapez E, et al. KRAS mutation testing in patients with metastatic colorectal carcinoma: an 18-month experience emphasizing the risk of false-negative results. J Clin Oncol 2010;28:15s (Suppl; abstr 3572).
    • (2010) J Clin Oncol , vol.28
    • Bibeau, F.1    Frugier, H.2    Crapez, E.3
  • 20
    • 84860473076 scopus 로고    scopus 로고
    • Impact of the amount of tumor cells in tissue samples for detection of KRAS mutations in colorectal cancer
    • abstr 3571
    • Selves J, Grand D, Guimbaud R, et al. Impact of the amount of tumor cells in tissue samples for detection of KRAS mutations in colorectal cancer. J Clin Oncol 2010;28:15s (Suppl; abstr 3571).
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Selves, J.1    Grand, D.2    Guimbaud, R.3
  • 22
    • 81755163491 scopus 로고    scopus 로고
    • A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer
    • Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, et al. A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. Pharmacogenomics J 2011;11:437-443.
    • (2011) Pharmacogenomics J , vol.11 , pp. 437-443
    • Ho-Pun-Cheung, A.1    Assenat, E.2    Bascoul-Mollevi, C.3
  • 23
    • 79955373880 scopus 로고    scopus 로고
    • EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer
    • Ho-Pun-Cheung A, Assenat E, Bascoul-Mollevi C, et al. EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer. Int J Cancer 2011;128:2938-2946.
    • (2011) Int J Cancer , vol.128 , pp. 2938-2946
    • Ho-Pun-Cheung, A.1    Assenat, E.2    Bascoul-Mollevi, C.3
  • 24
    • 0030990974 scopus 로고    scopus 로고
    • Pathological features of rectal cancer after preoperative radiochemotherapy
    • DOI 10.1007/s003840050072
    • Dworak O, Keilholz L, Hoffmann A. Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis 1997;12:19-23. (Pubitemid 27138353)
    • (1997) International Journal of Colorectal Disease , vol.12 , Issue.1 , pp. 19-23
    • Dworak, O.1    Keilholz, L.2    Hoffmann, A.3
  • 26
    • 77949542415 scopus 로고    scopus 로고
    • KRAS status analysis and anti-EGFR therapies:is comprehensiveness a biologist's fancy or a clinical necessity?
    • Lopez-Crapez E, Mineur L, Emptas H, Lamy PJ. KRAS status analysis and anti-EGFR therapies: is comprehensiveness a biologist's fancy or a clinical necessity? Br J Cancer 2010;102:1074-1075.
    • (2010) Br J Cancer , vol.102 , pp. 1074-1075
    • Lopez-Crapez, E.1    Mineur, L.2    Emptas, H.3    Lamy, P.J.4
  • 27
    • 77349127129 scopus 로고    scopus 로고
    • KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: Comparison of methods and impact of histology
    • Weichert W, Schewe C, Lehmann A, et al. KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: comparison of methods and impact of histology. J Mol Diagn 2010;12: 35-42.
    • (2010) J Mol Diagn , vol.12 , pp. 35-42
    • Weichert, W.1    Schewe, C.2    Lehmann, A.3
  • 28
    • 75449084810 scopus 로고    scopus 로고
    • Perspectives on Emerging Technology (POET) College of American Pathologists: Northfield IL
    • Perspectives on Emerging Technology (POET). Report: KRAS Mutation Testing in Colorectal Cancer (CRCs). College of American Pathologists: Northfield, IL, 2009.
    • (2009) Report: KRAS Mutation Testing in Colorectal Cancer (CRCs)
  • 29
    • 77349103908 scopus 로고    scopus 로고
    • KRAS mutation: Comparison of testing methods and tissue sampling techniques in colon cancer
    • Franklin WA, Haney J, Sugita M, et al. KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer. J Mol Diagn 2010;12: 43-50.
    • (2010) J Mol Diagn , vol.12 , pp. 43-50
    • Franklin, W.A.1    Haney, J.2    Sugita, M.3
  • 31
    • 0031568919 scopus 로고    scopus 로고
    • Product differentiation by analysis of DNA melting curves during the polymerase chain reaction
    • DOI 10.1006/abio.1996.9916
    • Ririe KM, Rasmussen RP, Wittwer CT. Product differentiation by analysis of DNA melting curves during the polymerase chain reaction. Anal Biochem 1997;245: 154-160. (Pubitemid 27082244)
    • (1997) Analytical Biochemistry , vol.245 , Issue.2 , pp. 154-160
    • Ririe, K.M.1    Rasmussen, R.P.2    Wittwer, C.T.3
  • 32
    • 78649522401 scopus 로고    scopus 로고
    • KRAS analysis in colorectal carcinoma: Analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice
    • Sundstrom M, Edlund K, Lindell M, et al. KRAS analysis in colorectal carcinoma: analytical aspects of Pyrosequencing and allele-specific PCR in clinical practice. BMC Cancer 2010;10:660.
    • (2010) BMC Cancer , vol.10 , pp. 660
    • Sundstrom, M.1    Edlund, K.2    Lindell, M.3
  • 33
    • 44649156362 scopus 로고    scopus 로고
    • High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies
    • Do H, Krypuy M, Mitchell PL, et al. High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies. BMC Cancer 2008;8:142.
    • (2008) BMC Cancer , vol.8 , pp. 142
    • Do, H.1    Krypuy, M.2    Mitchell, P.L.3
  • 35
    • 70350462904 scopus 로고    scopus 로고
    • A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting
    • Whitehall V, Tran K, Umapathy A, et al. A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting. J Mol Diagn 2009;11:543-552.
    • (2009) J Mol Diagn , vol.11 , pp. 543-552
    • Whitehall, V.1    Tran, K.2    Umapathy, A.3
  • 36
    • 65549143792 scopus 로고    scopus 로고
    • The importance of KRAS mutations and EGF61A4G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer
    • Garm Spindler KL, Pallisgaard N, Rasmussen AA, et al. The importance of KRAS mutations and EGF61A4G polymorphism to the effect of cetuximab and irinotecan in metastatic colorectal cancer. Ann Oncol 2009;20:879-884.
    • (2009) Ann Oncol , vol.20 , pp. 879-884
    • Garm Spindler, K.L.1    Pallisgaard, N.2    Rasmussen, A.A.3
  • 37
    • 33746467644 scopus 로고    scopus 로고
    • Assessment of microsatellite instability in very small microdissected samples and in tumor samples that are contaminated with normal DNA
    • DOI 10.1097/00019606-200606000-00001, PII 0001960620060600000001
    • Trusky CL, Sepulveda AR, Hunt JL. Assessment of microsatellite instability in very small microdissected samples and in tumor samples that are contaminated with normal DNA. Diagn Mol Pathol 2006;15:63-69. (Pubitemid 44350481)
    • (2006) Diagnostic Molecular Pathology , vol.15 , Issue.2 , pp. 63-69
    • Trusky, C.L.1    Sepulveda, A.R.2    Hunt, J.L.3
  • 38
  • 39
    • 32844474337 scopus 로고    scopus 로고
    • Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA-protein crosslinks and DNA breaks
    • Liu Y, Li CM, Lu Z, et al. Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA-protein crosslinks and DNA breaks. Front Biosci 2006;1:991-997. (Pubitemid 43253454)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.1 , pp. 991-997
    • Liu, Y.1    Li, C.M.2    Lu, Z.3    Ding, S.4    Yang, X.5    Mo, J.6
  • 40
    • 0036898005 scopus 로고    scopus 로고
    • Effect of fixatives and tissue processing on the content and integrity of nucleic acids
    • Srinivasan M, Sedmak D, Jewell S. Effect of fixatives and tissue processing on the content and integrity of nucleic acids. Am J Pathol 2002;161:1961-1971. (Pubitemid 35434840)
    • (2002) American Journal of Pathology , vol.161 , Issue.6 , pp. 1961-1971
    • Srinivasan, M.1    Sedmak, D.2    Jewell, S.3
  • 41
    • 0032755991 scopus 로고    scopus 로고
    • A high frequency of sequence alterations is due to formalin fixation of archival specimens
    • Williams C, Ponten F, Moberg C, et al. A high frequency of sequence alterations is due to formalin fixation of archival specimens. Am J Pathol 1999;155:1467-1471.
    • (1999) Am J Pathol , vol.155 , pp. 1467-1471
    • Williams, C.1    Ponten, F.2    Moberg, C.3
  • 42
    • 79961025560 scopus 로고    scopus 로고
    • Metastatic colorectal cancer KRAS genotyping in routine practice: Results and pitfalls
    • Lamy A, Blanchard F, Le Pessot F, et al. Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls. Mod Pathol 2011;24:1090-1100.
    • (2011) Mod Pathol , vol.24 , pp. 1090-1100
    • Lamy, A.1    Blanchard, F.2    Le Pessot, F.3
  • 43
    • 81155159839 scopus 로고    scopus 로고
    • Does neoadjuvant therapy alter KRAS and/or MSI results in rectal adenocarcinoma testing?
    • Ondrejka SL, Schaeffer DE, Jakubowski MA, et al. Does neoadjuvant therapy alter KRAS and/or MSI results in rectal adenocarcinoma testing? Am J Surg Pathol 2011; 35:1327-1330.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1327-1330
    • Ondrejka, S.L.1    Schaeffer, D.E.2    Jakubowski, M.A.3
  • 44
    • 9244263625 scopus 로고    scopus 로고
    • The use of whole genome amplification in the study of human disease
    • DOI 10.1016/j.pbiomolbio.2004.01.007, PII S0079610704000185
    • Hughes S, Arneson N, Done S, Squire J. The use of whole genome amplification in the study of human disease. Prog Biophys Mol Biol 2005;88: 173-189. (Pubitemid 39547777)
    • (2005) Progress in Biophysics and Molecular Biology , vol.88 , Issue.1 , pp. 173-189
    • Hughes, S.1    Arneson, N.2    Done, S.3    Squire, J.4
  • 45
    • 79952771911 scopus 로고    scopus 로고
    • Should oncologists be aware in their clinical practice of KRAS molecular analysis?
    • Santini D, Galluzzo S, Gaeta L, et al. Should oncologists be aware in their clinical practice of KRAS molecular analysis? J Clin Oncol 2011;29: e206-e207.
    • (2011) J Clin Oncol , vol.29
    • Santini, D.1    Galluzzo, S.2    Gaeta, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.