Progress in modelling acute lung injury in a pre-clinical mouse model

European Respiratory Journal

Volumn 39, Issue 5, 2012, Pages 1062-1063

  Matthay, Michael A ^a   Howard, James P ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR;

ACUTE LUNG INJURY; DISEASE MODEL; EDITORIAL; LUNG ALVEOLUS EPITHELIUM; LUNG CLEARANCE; LUNG COMPLIANCE; LUNG EDEMA; LUNG ENDOTHELIUM; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXYGENATION; PRIORITY JOURNAL;

ACUTE LUNG INJURY; ANIMALS; DISEASE MODELS, ANIMAL; HYDROCHLORIC ACID; MALE; PNEUMONIA; TRANSLATIONAL MEDICAL RESEARCH;

EID: 84860458094     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00204211     Document Type: Editorial

References (10)

1. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-1349. (Pubitemid 30408719)
2. Matute-Bello G, Frevert CW, Martin TR. Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2008; 295: L379-L399.
3. Ware LB. Modeling human lung disease in animals. Am J Physiol Lung Cell Mol Physiol 2008; 294: L149-L150. (Pubitemid 351253349)
4. Bastarache JA, Blackwell TS. Development of animal models for the acute respiratory distress syndrome. Dis Model Mech 2009; 2: 218-223.
5. Matute-Bello G, Downey G, Moore BB, et al. An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol 2011; 44: 725-738.
6. Patel BV, Wilson MR, Takata M. Resolution of acute lung injury and inflammation: a translational mouse model. Eur Respir J 2012; 39: 1162-1170.
7. Calfee CS, Ware LB, Eisner MD, et al. Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax 2008; 63: 1083-1089.
8. Matthay MA, Wiener-Kronish JP. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 1990; 142: 1250-1257.
9. Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001; 163: 1376-1383. (Pubitemid 32506602)
10. +Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury. J Clin Invest 2009; 119: 2898-2913.