Molecular characterization of immunoglobulin genes

Basic Methods in Antibody Production and Characterization

Volumn , Issue , 2000, Pages 169-192

  Ladiges, Warren ^a   Osman, Gamal E ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Antigenics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84860443906     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (61)

1. Akolkar, P. N., Sikder, S. K., Bhattacharya, S. B., Liao, J., Gruezo, F., Morrison, S. L., and Kabat, E. A., Different V-L and V-H germ-line genes are used to produce similar combining sites with specificity for alpha (1, 6) dextrans, J. Immunol., 138, 4472-4479, 1987.
2. Alt, F. W., Blackwell, T. K., and Yancopoulos, G. D., Development of the primary antibody repertoire, Science, 238, 1079-1087, 1987.
3. b family of antibodies: somatic mutation evident in a gamma-2a variable region, Cell, 24, 625-637, 1981.
4. Bernard, O. D., Hozumi, N., and Tonegawa, S., Sequences of mouse immunoglobulin light chain genes before and after somatic changes, Cell, 15, 1133-1144, 1978.
5. Brodeur, P. H. and Riblet, R., The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes, Eur. J. Immunol., 14, 922-930, 1984.
6. H gene family clusters, J. Exp. Med., 168, 2261-2278, 1988.
7. Chaudhary, V. K., Batra, J. K., Gallo, M. G., Willingham, M. C., Fitzgerald, D. J., and Pastan, I., A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunoglobulin, Proc. Natl. Acad. Sci. U.S.A., 87, 1066-1070, 1990.
8. Chiang, Y. L., Sheng-Dong, R., Brow, M. A., and Larrick, J. W., Direct cDNA cloning of the rearranged immunoglobulin variable region, BioTechniques, 7, 360-366, 1989.
9. Coloma, M. J., Larrick, J. W., Ayala, M., and Gavilondo-Cowley, J. V., Primer design for the cloning of immunoglobulin heavy-chain leader-variable regions from mouse hybridoma cells using the PCR, BioTechniques, 11, 152-154, 1991.
10. K sequences: implications for the number of germline V kappa genes, J. Mol. Appl. Genet, 1, 103-116, 1981.
11. Dattamajumdar, A. K., Jacobson, D. P., Ladiges, W., Hood, L. E., and Osman, G. E., Characterization of the mouse Tcra-V22 gene subfamily, Immunogenetics, 43, 141-151, 1996a.
12. Dattamajumdar, A. K., Li, S. W., Jacobson, D. P., Hood, L. E., and Osman, G. E., Rapid cloning of any rearranged mouse immunoglobulin variable genes, Immunoge-netics, 44, 432-440, 1996b.
13. D’Hoostelaere, L. A. and Klinman, D., Characterization of new mouse V kappa groups, J. Immunol., 145, 2706-2712, 1990.
14. H sequences, Immunol. Today, 5, 85-86, 1984.
15. Eisen, H. N. and Reilly, E. B., Lambda chains and genes in inbred mice, Ann. Rev. Immunol., 3, 337-365, 1985.
16. Embleton, M. J., Gorochov, G., Jones, P.T., and Winter, G., In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells, Nucl. Acids Res., 20(25), 3831-3837, 1992.
17. Ferguson, S. E., Cancro, M. P., and Osborne, B. A., Analysis of a novel V(H)S107 haplotype in CLA-1 and WSA mice. Evidence for gene conversion among IgV(H) genes in outbred populations, J. Exp. Med., 170, 1811-1823, 1989.
18. Gavilondo-Cowley, J. V., Coloma, M. J., Vazquez, J., Ayala, M., Macias, A., Fry, K. E., and Larrick, J. W., Specific amplification of rearranged immunoglobulin variable region genes from mouse hybridoma cells, Hybridoma, 9(5), 407-417, 1990.
19. Gefter, M. L., Margolies, M. N., Near, R. I., and Wysocki, L. J., Analysis of the anti-azobenzenearsonate response at the molecular level, Ann. Inst. Pasteur Immunol., 135, 17-30, 1984.
20. Goodnow, C. C., Crossbie, J., Aldelstein, S., Lavoie, T. B., Smith-Gill, S., Brink, R. A., Pritchard-Briscoe, H., Wotherspoon, J. S., Loblay, R. H., Raphael, K., Trent, R. J., and Basten, A., Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice, Nature, 334, 676-682, 1988.
21. Grosschedl, R., Weaver, D., Baltimore, D., and Costantini, F., Introduction of a ^ immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody, Cell, 38, 647-658, 1984.
22. Hartman, A. B. and Rudikoff, S., VH genes encoding the immune response to beta-(1, 6)-galactan: somatic mutation in IgM molecules, EMBO J, 3(12), 3023-3030, 1984.
23. Hayashi, K., Manipulation of DNA by PCR, in PCR: The Polymerase Chain Reaction, K. B. Mullis, F. Ferre, and R. A. Gibbs, Eds., Birkhauser Boston, Cambridge, MA, 3-13, 1994.
24. Heinrichs, A., Milstein, C., and Gherardi, E. A., Universal cloning and direct sequencing of rearranged antibody V genes using C region primers, biotin-captured cDNA and one-sided PCR, J. Immunol. Methods, 178, 241-251, 1995.
25. Jones, S. T. and Bendig, M. M., Rapid PCR-cloning of full-length mouse immunoglobulin variable regions, Bio/Technology, 9, 88-89, 1991.
26. Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C., Sequences of Proteins of Immunological Interest, U.S. Department of Health and Human Services, MD, 1991.
27. Kettleborough, C. A., Saldhana, J., Ansell, K. H., and Bendig, M. M., Optimization of primers for cloning libraries of mouse immunoglobulin genes using the polymerase chain reaction, Eur. J. Immunol, 23, 206-211, 1993.
28. Kofler, R., Geley, S., Hofler, H., and Helmberg, A., Mouse variable-regions gene families: complexity, polymorphism and use in non-autoimmune responses, Immunol. Rev., 128, 5-21, 1992.
29. Kutemeier, G., Harloff, C., and Mocikat, R., Rapid isolation of immunoglobulin genes from cell lysates of rat hybridomas by polymerase chain reaction, Hybridoma, 11(1), 23-32, 1992.
30. Larrick, J. M., Danielsson, L., Brenner, C., Abrahamson, M., Fry, K., and Borrebaeck, C.A.K., Rapid cloning of rearranged immunoglobulin genes from human hybdridoma cells using mixed primers and the polymerase chain reaction, Biochem. Biophys. Res. Commun, 160, 1250-1256, 1989.
31. Larrick, J. W., Coloma, M. J., Del Valle, J., Fernandez, M. E., Fry, K. E., and Gavilondo-Cowley, J. V., Immunoglobulin V regions of a bactericidal anti-Neisseria meningitidis outer membrane protein monoclonal antibody, Scand. J. Immunol., 32, 121-128, 1990.
32. Livant, D., Blatt, C., and Hood, L., One heavy chain variable region gene segment subfamily in BALB/c mouse contains 500-1000 or more members, Cell, 47, 461-470, 1986.
33. Loh, E. Y., Elliott, J. F., Cwirla, S., Lanier, L.L., and Davis, M. M., Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain, Science, 243, 217-210, 1989.
34. Lundberg, K. S., Shoemaker, D. D., Adams, M. W. W., Short, J. M., Sorge, J. A., and Mathur, E. J., High fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus Furiossus, Gene, 108, 1-6, 1991.
35. Matsuda, T. and Kabat, E. A., Variable region cDNA sequences and antigen binding specificity of mouse monoclonal antibodies to isomaltosyl oligosaccharides coupled to proteins: T-dependent analogues of alpha-(1-6)-dextran, J. Immunol, 142, 863-870, 1989.
36. Max, E. E., Maizel, J. V., and Leder, P., The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes, J. Biol. Chem., 256, 5116-5120, 1981.
37. Meek, K., Rathbun, G., Reininger, L., Jaton, J. C., Kofler, R., Tucker, P., and Capra, J. D., Organization of the murine immunoglobulin VH complex: placement of two new VH families (VH10 and VH11) and analysis of VH family clustering and interdigitation, Mol. Immunol., 27, 1073-1081, 1990.
38. Orlandi, R., Gussow, D. H., Jones, P. T., and Winter, G., Cloning immunoglobulin variable domains for expression by the polymerase chain reaction, Proc. Natl. Acad. Sci. U.S.A., 86, 3833-3837, 1989.
39. H repertoire of fetal liver-derived pre-B cells is influenced by the expression of a gene liked to X-linked immune deficiency, J. Immunol., 148, 1928-1933, 1992.
40. Pennell, C. A., Mercolino, T. J., Grdina, T. A., Arnold, L. W., Houghton, G., and Clarke, S., Biased immunoglobulin variable region gene expression by Ly-1 B cells due to clonal selection, Eur. J. Immunol, 19, 1289-1295, 1989.
41. κ groups based on the partial amino acid sequence to the first invariant tryptophan: impact of 14 new sequences from IgG myeloma proteins, Mol. Immunol., 12, 1619-1630, 1982.
42. Ratech, H., Rapid cloning of rearranged immunoglobulin heavy chian genes from human B-cell lines using anchored polymerase chain reaction, Biochem. Biophys. Res. Commun., 182, 1260-1263, 1992.
43. H gene family encodes anti-bromelinized mouse red blood cell autoantibodies, Eur. J. Immunol., 18, 1521-1526, 1988.
44. Rusconi, S. and Kohler, G., Transmission and expression of a specific pair of rearranged immunoglobulin μ and κ genes in a transgenic mouse line, Nature, 314, 330-334, 1985.
45. Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., and Erlich, H. A., Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase, Science, 239, 487-491, 1988.
46. Sakano, H., Maki, R., Kurosawa, Y., Roeder, W., and Tonegawa, S., Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes, Nature, 286, 676-683, 1980.
47. Sanchez, P., Marche, P. N., Rueff-Juy, D., and Cazenave, P. A., Mouse V-lambda-X gene sequence generates no junctonal diversity and is conserved in mammalian species, J. Immunol., 144, 2816-2820, 1990.
48. Shapiro, M. A. and Weigert, M., How immunoglobulin V kappa genes rearrange, J. Immunol, 139, 3834-3839, 1987.
49. Shefner, R., Mayer, R., Kaushik, A., D’Eustachio, P., Bona, C., and Diamond, B., Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain, J. Immunol, 145, 1609-1614, 1990.
50. Siedman, J. G., Max, E. E., and Leder, P. A., A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation, Nature, 280, 370-375, 1979.
51. Songsivilai, S., Bye, J. M., Marks, J. D., and Hughes-Jones, N. C., Cloning and sequencing of human lambda immunoglobulin genes by polymerase chain reaction, Eur. J. Immunol., 20, 2661-2666, 1990.
52. Storb, U., Pinkert, C., Arb, B., Engler, P., Gollahon, K., Manz, J., Brady, W., and Brinster, R., Transgenic mice with m and k genes encoding antiphosphorylcholine antibodies, J. Exp. Med., 164, 627-641, 1986.
53. Strohal, R., Helmberg, A., Kroemer, G., and Kofler, R., Mouse V kappa gene classification by nucleic acid sequence similarity, Immunogenetics, 30, 475-493, 1989.
54. Tonegawa, S., Maxam, A. M., Tizard, R., Bernard, O. D., and Gilbert, W., Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain, Proc. Natl. Acad. Sci. U.S.A., 75, 1485-1489, 1978.
55. H gene families, J. Immunol., 147, 3215-3223, 1991.
56. Valiante, N. M. and Caton, A. J., A new Igk-V kappa gene family in the mouse, Immunogenetics, 32, 345-350, 1990.
57. Weiss, S. and Wu, G. E., Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains, EMBO J., 6, 927-932, 1987.
58. Williams, J. F., Optimization strategies for the polymerase chain reaction, Bio Techniques, 7, 762-769, 1989.
59. H gene families are found in VDJ regions of polyclonally activated B-lymphocytes, EMBO J., 4, 2861-2867, 1985.
60. Zhou, H., Fisher, R. J., and Papas, T. S., Optimization of primer sequences for mouse scFv repertoire display library construction, Nucl. Acids Res, 22, 888-889, 1994.
61. Zwickl, M., Zaninetta, D., McMaster, G. K., and Hardman, N., Selective cloning of B cell hybridoma-specific rearranged immunoglobulin gene loci using the polymerase chain reaction, J. Immunol. Methods, 130, 49-55, 1990.