Elevated serum concentrations of inflammatory cytokines and chemokines in patients with haemorrhagic fever with renal syndrome

Journal of International Medical Research

Volumn 40, Issue 2, 2012, Pages 648-656

  Wang, P Z ^a   Li, Z D ^b   Yu, H T ^a   Zhang, Y ^a   Wang, W ^a   Jiang, W ^a   Bai, X F ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Disease Phase; Disease Severity; Haemorrhagic fever with renal syndrome (HFRS); Hantavirus; Inflammatory Chemokines; Inflammatory Cytokines

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FEVER; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; HYPOTENSION; MALE; OLIGURIA; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL;

EID: 84860435268     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001204000227     Document Type: Article

References (45)

1. Plyusnin A, Morzunov SP: Virus evolution and genetic diversity of hantaviruses and their rodent hosts. Curr Top Microbiol Immunol 2001; 256: 47-75.
2. Schmaljohn C, Hjelle B: Hantaviruses: a global disease problem. Emerg Infect Dis 1997; 3: 95-104.
3. Krüger DH, Schönrich G, Klempa B: Human pathogenic hantaviruses and prevention of infection. Hum Vaccine 2011; 7: 685-693
4. Peters CJ, Simpson GL, Levy H: Spectrum of hantavirus infection: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Annu Rev Med 1999; 50: 531-545.
5. Zhang YZ, Zou Y, Fu ZF, et al: Hantavirus infection in humans and animals, China. Emerg Infect Dis 2010; 16: 1195-1203.
6. World Health Organization: Haemorrhagic fever with renal syndrome: memorandum from a WHO meeting. Bull World Health Organ 1983; 61: 269-275.
7. Faulde M, Sobe D, Kimmig P, et al: Renal failure and hantavirus infection in Europe. Nephrol Dial Transplant 2000; 15: 751-753.
8. Cosgriff TM: Mechanisms of disease in Hantavirus infection: pathophysiology of hemorrhagic fever with renal syndrome. Rev Infect Dis 1991; 13: 97-107.
9. Maes P, Clement J, Gavrilovskaya I, et al: Hantaviruses: immunology, treatment and prevention. Viral Immunol 2004; 17: 481-497.
10. + T lymphocytes in PBMC from the patients with hemorrhagic fever with renal syndrome. Intern Emerg Med 2011; epub ahead of print.
11. Wang M, Wang J, Zhu Y, et al: Cellular immune response to Hantaan virus nucleocapsid protein in the acute phase of hemorrhagic fever with renal syndrome: correlation with disease severity. J Infect Dis 2009; 199: 188-195.
12. + T cells in patients with hemorrhagic fever with renal syndrome. Viral Immunol 2009; 22: 253-260.
13. Saksida A, Wraber B, Avšič-Županc T: Serum levels of inflammatory and regulatory cytokines in patients with hemorrhagic fever with renal syndrome. BMC Infect Dis 2011; 11: 142-150.
14. Krakauer T, Leduc JW, Krakauer H: Serum levels of tumor necrosis factor-alpha, interleukin-1, and interleukin-6 in hemorrhagic fever with renal syndrome. Viral Immunol 1995; 8: 75-79.
15. Krakauer T, Leduc JW, Morrill JC, et al: Serum levels of alpha and gamma interferons in hemorrhagic fever with renal syndrome. Viral Immunol 1994; 7: 97-101.
16. Linderholm M, Ahlm C, Settergren B, et al: Elevated plasma levels of tumor necrosis factor (TNF)-α, soluble TNF receptors, interleukin (IL)-6, and IL-10 in patients with hemorrhagic fever with renal syndrome. J Infect Dis 1996; 173: 38-43.
17. MacNeil A, Nichol ST, Spiropoulou CF: Hantavirus pulmonary syndrome. Virus Res 2011; 162: 138-147.
18. Cheung CY, Poon LL, Lau AS, et al: Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 2002; 360: 1831-1837.
19. Chakravarti A, Kumaria R: Circulating levels of tumour necrosis factor-α & interferon-γ in patients with dengue & dengue haemorrhagic fever during an outbreak. Indian J Med Res 2006; 123: 25-30.
20. Sundstrom JB, McMullan LK, Spiropoulou CF, et al: Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. J Virol 2001; 75: 6070-6085.
21. Jiang H, Wang PZ, Zhang Y, et al: Hantaan virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon, interleukin-6 and tumor necrosis factor-alpha. Virology 2008; 380: 52-59.
22. Ministry of Health, People's Republic of China: Prevention and Treatment Program of Epidemic Hemorrhagic Fever. Categorization number 2360028701. China: Laws and Regulations of State Council, 1987.
23. Yanagihara R, Silverman DJ: Experimental infection of human vascular endothelial cells by pathogenic and non-pathogenic hanta -viruses. Arch Virol 1990; 111: 281-286.
24. Pensiero MN, Sharefkin JB, Dieffenbach CW, et al: Hantaan virus infection of human endothelial cells. J Virol 1992; 66: 5929-5936.
25. Peters CJ, Zaki SR: Role of the endothelium in viral hemorrhagic fevers. Crit Care Med 2002; 30: 5268-5273.
26. Khaiboullina SF, Morzunov SP, St Jeor SC: Hantaviruses: molecular biology, evolution and pathogenesis. Curr Mol Med 2005; 5: 773-790.
27. Mackow ER, Gavrilovskaya IN: Hantavirus regulation of endothelial cell functions. Thromb Haemost 2009; 102: 1030-1041.
28. Song JS, Min CH, Kang E, et al: Expression of ICAM-1 on the Hantaan virus-infected human umbilical vein endothelial cells. Korean J Intern Med 1999; 14: 47-54.
29. Schönrich G, Rang A, Lütteke N, et al; Hantavirus-induced immunity in rodent reservoirs and humans. Immunol Rev 2008; 225: 163-189.
30. Outinen TK, Mäkelä SM, Ala-Houhala IO, et al: The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations. BMC Infect Dis 2010; 10: 132-139.
31. Klingström J, Plyusnin A, Vaheri A, et al: Wild-type Puumala hantavirus infection induces cytokines, C-reactive protein, creatinine and nitric oxide in cynomolgus macaques. J Virol 2002; 76: 444-449.
32. Green S, Vaughn DW, Kalayanarooj S, et al: Early immune activation in acute dengue illness is related to development of plasma leakage and disease severity. J Infect Dis 1999; 179: 755-762.
33. Green S, Vaughn DW, Kalayanarooj S, et al: Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity. J Med Virol 1999; 59: 329-334.
34. Marta RF, Montero VS, Hack CE, et al: Proinflammatory cytokines and elastase-α-1-antitrypsin in Argentine hemorrhagic fever. Am J Trop Med Hyg 1999; 60: 85-89.
35. Jablons DM, Mulé JJ, Mclntosh JK, et al: IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans. J Immunol 1989; 142: 1542-1547.
36. Sprague AH, Khalil RA: Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol 2009; 78: 539-552.
37. Liu JM, Zhu Y, Xu ZW, et al: Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome. Clin Immunol 2006; 119: 245-251.
38. Geimonen E, Neff S, Raymond T, et al: Pathogenic and non-pathogenic hantaviruses differentially regulate endothelial cell responses. Proc Natl Acad Sci USA 2002; 99: 13837-13842.
39. Liu MT, Chen BP, Oertel P, et al: The T cell chemoattractant IFN-inducible protein 10 is essential in host defense against viral-induced neurologic disease. J Immunol 2000; 165: 2327-2330.
40. Hooper JW, Larsen T, Custer DM, et al: A lethal disease model for hantavirus pulmonary syndrome. Virology 2001; 289: 6-14.
41. Mukaida N: Interleukin-8: an expanding universe beyond neutrophil chemotaxis and activation. Int J Hematol 2000; 72: 391-398.
42. Chertov O, Michiel DF, Xu L, et al: Identification of defensin-1, defensin-2 and CAP37/ azurocidin as T cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem 1996; 271: 2935-2940.
43. Chen J, Subbarao K: The immunobiology of SARS. Annu Rev Immunol 2007; 25: 443-472.
44. Mahanty S, Bausch DG, Thomas RL, et al: Low levels of interleukin-8 and interferon-inducible protein-10 in serum are associated with fatal infections in acute Lassa fever. J Infect Dis 2001; 183: 1713-1721.
45. Borges AA, Campos GM, Moreli ML, et al: Role of mixed Th1 and Th2 serum cytokines on pathogenesis and prognosis of hantavirus pulmonary syndrome. Microbes Infect 2008; 10: 1150-1157.