Using bedtime (PM) and early morning (AM) urine cortisol/creatinine ratios to evaluate pituitary-adrenal function in an office practice

Endocrine Practice

Volumn 17, Issue 4, 2011, Pages 591-597

  Burch, Warner ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CREATININE; HYDROCORTISONE;

ADULT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; CREATININE URINE LEVEL; CUSHING SYNDROME; DRUG DOSE REDUCTION; FATIGUE; FEMALE; HEALTH SERVICE; HUMAN; HYDROCORTISONE URINE LEVEL; HYPOPHYSIS ADRENAL SYSTEM; HYPOPITUITARISM; LABORATORY TEST; MAJOR CLINICAL STUDY; MALAISE; MALE; METABOLIC DISORDER; OUTPATIENT; PHYSICAL EXAMINATION; URINALYSIS; WEIGHT REDUCTION;

ADULT; AGED; CREATININE; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; PITUITARY-ADRENAL SYSTEM; TIME FACTORS;

EID: 84860415412     PISSN: 1530891X     EISSN: 19342403     Source Type: Journal    
DOI: 10.4158/EP10177.OR     Document Type: Article

References (10)

1. Weitzman ED, Fukushima D, Nogeire C, Roffwarg H, Gallagher TF, Hellman L. Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects. J Clin Endocrinol Metab. 1971;33:14-22.
2. Kong WM, Alaghband-Zadeh J, Jones J, Carter G, O'Shea D. The midnight to morning urinary cortisol increment is an accurate, noninvasive method for assessment of the hypothalamic-pituitary-adrenal axis. J Clin Endocrinol Metab. 1999;84:3093-3098. (Pubitemid 30646928)
3. Chan KC, Lit LC, Law EL, et al. Diminished urinary free cortisol excretion in patients with moderate and severe renal impairment. Clin Chem. 2004;50:757-759. (Pubitemid 38429343)
4. Castro M, Elias PC, Quidute AR, Halah FP, Moreira AC. Out-patient screening for Cushing's syndrome: the sensitivity of the combination of circadian rhythm and overnight dexamethasone suppression salivary cortisol tests. J Clin Endocrinol Metab. 1999;84:878-882. (Pubitemid 29138212)
5. Raff H, Raff JL, Findling JW. Late-night cortisol as a screening test for Cushing's syndrome. J Clin Endocrinol Metab. 1998;83:2681-2686. (Pubitemid 28493760)
6. Papanicolaou DA, Mullen N, Kyrou I, Nieman LK. Nighttime salivary cortisol: a useful test for the diagnosis of Cushing's syndrome. J Clin Endocrinol Metab. 2002; 87:4515-4521. (Pubitemid 35247034)
7. Carroll T, Raff H, Findling JW. Late-night salivary corti-sol for the diagnosis of Cushing syndrome: a meta-analysis. Endocr Pract. 2009;15:335-342.
8. Contreras LN, Hane S, Tyrrell JB. Urinary cortisol in the assessment of pituitary-adrenal function: utility of 24-hour and spot determinations. J Clin Endocrinol Metab. 1986;62:965-969. (Pubitemid 16106726)
9. Fujita H, Hata K, Ogata E, Kojima I. Spot determinations of urinary cortisol for screening of Cushing's syndrome. Endocrinol Jpn. 1991;38:441-444.
10. Masserini B, Morelli V, Bergamaschi S, et al. The limited role of midnight salivary cortisol levels in the diagnosis of subclinical hypercortisolism in patients with adrenal inci-dentaloma. Eur J Endocrinol. 2009;160:87-92.