Phytochemical screening and evaluation of cytotoxic, antimicrobial and cardiovascular effects of Gomphrena globosa L. (Amaranthaceae)

Journal of Medicinal Plants Research

Volumn 5, Issue 10, 2011, Pages 2006-2010

  Arcanjo, Daniel Dias Rufino ^a   de Albuquerque, Adonai Carvalho Medeiros ^a   Neto, Bernardo Melo ^a   Santana, Lorena Citó Lopes Resende ^a   Silva, Náiguel Castelo Branco ^a   Moita, Maria Marilza ^a   de Medeiros, Maria das Graças Freire ^a   Soares, Maria José dos Santos ^a   Citó, Antônia Maria das Graças Lopes ^a  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

Author keywords

Amaranthaceae; Antihypertensive; Artemia salina; Cytotoxicity; Gomphrena

Indexed keywords

ALKALOID; COUMARIN DERIVATIVE; GOMPHRENA GLOBOSA EXTRACT; PLANT EXTRACT; SAPONIN; SUGAR; UNCLASSIFIED DRUG;

AMARANTHACEAE; ANIMAL EXPERIMENT; ANTIHYPERTENSIVE ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTEMIA; ARTERIAL PRESSURE; ARTICLE; BIOASSAY; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; GOMPHRENA GLOBOSA; HEART RATE; MALE; NONHUMAN; PHYTOCHEMISTRY; PLANT LEAF; TOXICITY TESTING;

AMARANTHACEAE; ARTEMIA; ARTEMIA SALINA; GOMPHRENA; GOMPHRENA GLOBOSA;

EID: 84860415066     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Agra MF, Freitas PF, Barbosa FJM (2007). Synopsis of the plants known as medicinal and poisonous in Northeast of Brazil. Rev. Bras. Farmacogn., 17: 114-140.
2. Alves TMA, Silva AF, Brandão M, Grandi TSM, Smânia EFA, Smânia JA, Zani CL (2000). Biological screening of Brazilian medicinal plants. Mem. Inst. Oswaldo Cruz., 95: 367-373.
3. Bouillant ML, Redolfi P, Cantisani A, Chopin J (1978). Gomphrenol, a new methylenedioxyflavonol from the leaves of Gomphrena globosa (Amaranthaceae). Phytochem., 17: 2138-2140.
4. Buschi CA, Pomilio AB, Gros EG (1980). New methylated flavones from Gomphrena martiana. Phytochem., 19: 903-904.
5. Camejo RJ, Ascensão L, Bonet MA, Vallès J (2003). An ethnobotanical study of medicinal and aromatic plants in the Natural Park of "Serra de São Mamede" (Portugal). J. Ethnopharmacol., 89: 199-209.
6. Chiou WF, Huang YL, Chen CF, Chen CC (2001). Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum. Planta Med., 67: 282-284.
7. Chung MI, Gan KH, Lin CN, KO FN, Teng CM (1993). Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants. J. Nat. Prod., 56: 929-934.
8. Citó AMGL, Souza AA, Lopes JAD, Chaves MH, Costa FB, Sousa SAA, Amaral MPM (2003). Resina de Protium heptaphyllum March (Burceraceae): Composição Química do Óleo Essencial e Avaliação Citotóxica Frente a Artemia salina Leach. Anais Assoc. Bras. Quím., 52: 74-76.
9. Cordell GA, Quinn BML, Farnsworth NR (2001). The potential of alkaloids in drug discovery. Phytoter. Res., 15: 183-205.
10. Dadang D, Ohsawa K (2001). Efficacy of plant extracts for reducing larval populations of the diamondback moth, Plutella xylostella L. (Lepidoptera: Yponomeutidae) and cabbage webworm, Crocidolomia binotalis Zeller (Lepidoptera: Pyralidae), and evaluation of cabbage damage Appl. Entomol. Zool., 36: 143-149.
11. Farnsworth NR (1966). Biological and phytochemical screening of plants. J. Pharm. Sci., 55: 225-276.
12. França ISX, Souza JA, Baptista, RS, Britto VRS (2008). Medicina popular: benefícios e malefícios das plantas medicinais. Rev. Bras. Enferm., 61: 201-208.
13. Heuer S, Wray V, Metzger JW, Strack D (1992). Betacyanins from flowers of Gomphrena globosa. Phytochem., 31: 1801-1807.
14. Kawaguchi LYA, Nascimento ACP, Lima MS, Frigo L, Paula JAR, Tierra CCJ, Lopes MRAB (2007). Characterization of heart rate variability and baroreflex sensitivity in sedentary individuals and male athletes. Rev. Bras. Med. Esporte., 13:.207-212.
15. Lanfranchi PA, Somers VK (2002). Arterial baroreflex function and cardiovascular variability: interactions and implications. Am. J. Physiol. Regul. Integr. Comp. Physiol., 283: 815-826.
16. Lans CA (2006). Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. J. Ethnobiol. Ethnomed., 2: 45.
17. Lans CA (2007). Ethnomedicines used in Trinidad and Tobago for reproductive problems. J. Ethnobiol. Ethnomed., 3: 13.
18. Lieberman M (1999). A brine shrimp bioassay for measuring toxicity and remediation of chemicals. J. Chem. Educ., 76: 1689-1690.
19. López CAA (2006). Considerações gerais sobre plantas medicinais. Ambiente: Gestão e Desenvolvimento., 1: 19-27.
20. MacBae WD, Hudson JB, Towers GHN (1988). Studies on the pharmacological activity of amazonian euphorbiaceae. J. Ethnopharmacol., 22: 143-172.
21. Martin TJ, Cabanne F, Perdrizet E, Martin C (1978). The distribution of hydroxycinnamic acid amides in flowering plants. Phytochem., 17: 1927-1928.
22. McLaughlin JL, Rogers LL (1988). The use of biological assays to evaluate botanicals. Drug. Inf. J., 32: 513-524.
23. Meyer BN, Ferrigni NR, Putnam JE, Jacobsen LB, Nichols DE, McLaughlin JL (1982). Brine shrimp: A convenient general bioassay for active plant constituents. Planta Med., 45: 31-34.
24. Minale L, Piattelli M, De SS (1967). Pigments of centrospermae-VII: Betacyanins from Gomphrena globosa L. Phytochem., 6: 703-709.
25. N'guessan K, Tiébré MS, Aké AE, Zirihi GN (2009). Ethnobotanical study of plants used to treat arterial hypertension, in traditional medicine, by Abbey and Krobou Populations of Agboville (Côted'Ivoire). Eur. J. Sci. Res., 35: 85-98.
26. National Committee for Clinical Laboratory Standards; Performance standards for antimicrobial susceptibility testing: 15th Informational supplement 2005, NCCLS/CLSI document, M100-S15.
27. Nunes LCC, Galindo AB, Deus ASO, Arcanjo DDR, Randau KP, Xavier HS, Citó AMGL, Rolim NPJ (2009). Variabilidade sazonal dos constituintes da própolis vermelha e bioatividade em Artemia salina. Rev. Bras. Farmacogn., 19: 524-529.
28. Pomilio AB, Buschi CA, Tomes CN, Viale AA (1992). Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana. J. Ethnopharmacol., 36: 155-161.
29. Pomilio AB, Sola GAR, Mayer MAS, Rumi LS (1994). Antitumor and cytotoxic screen of 5,6,7-trisubstituted flavones from Gomphrena martiana. J. Ethnopharmacol., 44: 25-33.
30. Santos MRV, Nascimento NMS, Antoniolli AR, Medeiros IA (2006). Endothelium-derived factors and K+ channels are involved in the vasorelaxation induced by Sida cordifolia L. in the rat superior mesenteric artery. Pharm., 61: 466-469.
31. Sahpaz S, Bories C, Loiseau PM, Cortès D, Hocquemiller R, Laurens A, Cavé A (1994). Cytotoxic and Antiparasitic Activity from Annona senegalensis Seeds. Planta Med., 60: 538-540.
32. Soares MJS, Carvalho MCS, Carvalho BTF, Figueiredo AMS (2000). Spread of meticillin-resistant Staphylococcus aureus belonging to the Brazilian epidemic clone in a general hospital and emergence of heterogenous resistance to glycopeptide antibiotics among these isolates. J. Hosp. Infect., 44: 301-308.
33. Zani CL, Chaves PPG, Queiroz R, Oliveira AB, Cardoso JE, Anjos AMG, Grandi TSM (1995). Brine shrimp lethality assay as a prescreening system for anti- Trypanossoma cruzi activity. Phytomed., 2: 47.