Expression of connexin 57 in the olfactory epithelium and olfactory bulb

Neuroscience Research

Volumn 71, Issue 3, 2011, Pages 226-234

  Zhang, Chunbo ^a  

^a Illinois Institute of Technology   (United States)

Author keywords

Connexin; Gap junction; Gene expression; Murine; Neuron; Olfactory system

Indexed keywords

CONNEXIN 57; GAP JUNCTION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASAL CELL; GRANULE CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; JUXTAGLOMERULAR CELL; MALE; MITRAL CELL; MOUSE; NERVE CELL; NONHUMAN; OLFACTORY BULB; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; SIGNAL TRANSDUCTION;

ANIMALS; CONNEXINS; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; OLFACTORY BULB; OLFACTORY MUCOSA; SENSORY RECEPTOR CELLS; SMELL;

EID: 84860389981     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2011.07.1832     Document Type: Article

References (41)

1. Anderson C., Catoe H., Werner R. MIR-206 regulates connexin43 expression during skeletal muscle development. Nucleic Acids Res. 2006, 34:5863-5871.
2. Baschong W., Suetterlin R., Laeng R.H. Control of autofluorescence of archival formaldehyde-fixed, paraffin-embedded tissue in confocal laser scanning microscopy (CLSM). J. Histochem. Cytochem. 2001, 49:1565-1572.
3. Buntinas L., Zhang C., Restrepo D. Biophysical model of olfactory receptor neuron pairs reveals mechanism for gap junction mediated synchronized firing at threshold odor concentrations. Chem. Senses 2005, 30:A83-A84.
4. Choi P.S., Zakhary L., Choi W.Y., Caron S., Varez-Saavedra E., Miska E.A., McManus M., Harfe B., Giraldez A.J., Horvitz H.R., Schier A.F., Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 2008, 57:41-55.
5. Christie J.M., Bark C., Hormuzdi S.G., Helbig I., Monyer H., Westbrook G.L. Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron 2005, 46:761-772.
6. Christie J.M., Westbrook G.L. Lateral excitation within the olfactory bulb. J. Neurosci. 2006, 26:2269-2277.
7. Ciolofan C., Lynn B.D., Wellershaus K., Willecke K., Nagy J.I. Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina. Neuroscience 2007, 148:473-488.
8. Dbouk H.A., Mroue R.M., El-Sabban M.E., Talhouk R.S. Connexins: a myriad of functions extending beyond assembly of gap junction channels. Cell Commun. Signal. 2009, 7:4.
9. Hayar A., Shipley M.T., Ennis M. Olfactory bulb external tufted cells are synchronized by multiple intraglomerular mechanisms. J. Neurosci. 2005, 25:8197-8208.
10. Hombach S., Janssen-Bienhold U., Sohl G., Schubert T., Bussow H., Ott T., Weiler R., Willecke K. Functional expression of connexin57 in horizontal cells of the mouse retina. Eur. J. Neurosci. 2004, 19:2633-2640.
11. Janssen-Bienhold U., Trumpler J., Hilgen G., Schultz K., Muller L.P., Sonntag S., Dedek K., Dirks P., Willecke K., Weiler R. Connexin57 is expressed in dendro-dendritic and axo-axonal gap junctions of mouse horizontal cells and its distribution is modulated by light. J. Comp. Neurol. 2009, 513:363-374.
12. Kardami E., Dang X., Iacobas D.A., Nickel B.E., Jeyaraman M., Srisakuldee W., Makazan J., Tanguy S., Spray D.C. The role of connexins in controlling cell growth and gene expression. Prog. Biophys. Mol. Biol. 2007, 94:245-264.
13. Kihara A.H., de Castro L.M., Moriscot A.S., Hamassaki D.E. Prolonged dark adaptation changes connexin expression in the mouse retina. J. Neurosci. Res. 2006, 83:1331-1341.
14. Koling A., Sandmark B., Rask-Andersen H., Deuschl H. Gap junctions in the human olfactory mucosa as demonstrated by freeze-fracture electron microscopy. Cell Biol. Int. Rep. 1988, 12:563.
15. Kosaka T., Deans M.R., Paul D.L., Kosaka K. Neuronal gap junctions in the mouse main olfactory bulb: morphological analyses on transgenic mice. Neuroscience 2005, 134:757-769.
16. Kosaka T., Kosaka K. Neuronal gap junctions in the rat main olfactory bulb, with special reference to intraglomerular gap junctions. Neurosci. Res. 2003, 45:189-209.
17. Kosaka T., Kosaka K. Neuronal gap junctions between intraglomerular mitral/tufted cell dendrites in the mouse main olfactory bulb. Neurosci. Res. 2004, 49:373-378.
18. Kosaka T., Kosaka K. Intraglomerular dendritic link connected by gap junctions and chemical synapses in the mouse main olfactory bulb: electron microscopic serial section analyses. Neuroscience 2005, 131:611-625.
19. Kreuzberg M.M., Deuchars J., Weiss E., Schober A., Sonntag S., Wellershaus K., Draguhn A., Willecke K. Expression of connexin30.2 in interneurons of the central nervous system in the mouse. Mol. Cell Neurosci. 2008, 37:119-134.
20. Lauf U., Giepmans B.N., Lopez P., Braconnot S., Chen S.C., Falk M.M. Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cells. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:10446-10451.
21. Miragall F., Hwang T.K., Traub O., Hertzberg E.L., Dermietzel R. Expression of connexins in the developing olfactory system of the mouse. J. Comp. Neurol. 1992, 325:359-378.
22. Miragall F., Simburger E., Dermietzel R. Mitral and tufted cells of the mouse olfactory bulb possess gap junctions and express connexin43 mRNA. Neurosci. Lett. 1996, 216:199-202.
23. Pereda A., O'Brien J., Nagy J.I., Smith M., Bukauskas F., Davidson K.G., Kamasawa N., Yasumura T., Rash J.E. Short-range functional interaction between connexin35 and neighboring chemical synapses. Cell Commun. Adhes. 2003, 10:419-423.
24. Pfeifer I., Anderson C., Werner R., Oltra E. Redefining the structure of the mouse connexin43 gene: selective promoter usage and alternative splicing mechanisms yield transcripts with different translational efficiencies. Nucleic Acids Res. 2004, 32:4550-4562.
25. Rash J.E., Davidson K.G., Kamasawa N., Yasumura T., Kamasawa M., Zhang C., Michaels R., Restrepo D., Ottersen O.P., Olson C.O., Nagy J.I. Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb. J. Neurocytol. 2005, 34:307-341.
26. Rash J.E., Yasumura T., Davidson K.G., Furman C.S., Dudek F.E., Nagy J.I. Identification of cells expressing Cx43, Cx30, Cx26, Cx32 and Cx36 in gap junctions of rat brain and spinal cord. Cell Commun. Adhes. 2001, 8:315-320.
27. Reyher C.K., Lubke J., Larsen W.J., Hendrix G.M., Shipley M.T., Baumgarten H.G. Olfactory bulb granule cell aggregates: morphological evidence for interperikaryal electrotonic coupling via gap junctions. J. Neurosci. 1991, 11:1485-1495.
28. Schoppa N.E., Westbrook G.L. AMPA autoreceptors drive correlated spiking in olfactory bulb glomeruli. Nat. Neurosci. 2002, 5:1194-1202.
29. Shelley J., Dedek K., Schubert T., Feigenspan A., Schultz K., Hombach S., Willecke K., Weiler R. Horizontal cell receptive fields are reduced in connexin57-deficient mice. Eur. J. Neurosci. 2006, 23:3176-3186.
30. Solan J.L., Lampe P.D. Connexin43 phosphorylation: structural changes and biological effects. Biochem. J. 2009, 419:261-272.
31. Trosko J.E. Gap junctional intercellular communication as a biological "Rosetta stone" in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology, chemoprevention and chemotherapy. J. Membr. Biol. 2007, 218:93-100.
32. Viegas M.S., Martins T.C., Seco F., do Carmo A. An improved and cost-effective methodology for the reduction of autofluorescence in direct immunofluorescence studies on formalin-fixed paraffin-embedded tissues. Eur. J. Histochem. 2007, 51:59-66.
33. Vinken M., De R.E., Decrock E., De V.E., Leybaert L., Vanhaecke T., Rogiers V. Epigenetic regulation of gap junctional intercellular communication: more than a way to keep cells quiet?. Biochim. Biophys. Acta 2009, 1795:53-61.
34. Yu W., Dahl G., Werner R. The connexin43 gene is responsive to oestrogen. Proc. Biol. Sci. 1994, 255:125-132.
35. Zappalà A., Parenti R., La Della F., Cicirata V., Cicirata F. Expression of connexin57 in mouse development and in harmaline-tremor model. Neuroscience 2010, 171:1-11.
36. Zhang C. Gap junctions in olfactory neurons modulate olfactory sensitivity. BMC Neurosci. 2010, 11:108.
37. Zhang C., Finger T.E., Restrepo D. Activity-dependent regulation of connexin expression in the olfactory epithelium. Chem. Senses 2007, 32:A70.
38. Zhang C., Finger T.E., Restrepo D. Mature olfactory receptor neurons express connexin 43. J. Comp. Neurol. 2000, 426:1-12.
39. Zhang C., Restrepo D. Understanding the role of gap junctions in olfactory function. Chem. Senses 2005, 30:A1.
40. Zhang C., Restrepo D. Expression of connexin 45 in the olfactory system. Brain Res. 2002, 929:37-47.
41. Zhang C., Restrepo D. Heterogeneous expression of connexin 36 in the olfactory epithelium and glomerular layer of the olfactory bulb. J. Comp. Neurol. 2003, 459:426-439.