Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase

Journal of Biological Chemistry

Volumn 287, Issue 18, 2012, Pages 14545-14556

  Sen, Doyel ^a   Nandakumar, Divya ^a   Tang, Guo Qing ^a   Patel, Smita S ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGONISTIC ACTIVITY; DNA HELICASE; DNA REPLICATION FORKS; DNA UNWINDING; ENZYMATIC ACTIVITIES; FLUORESCENCE ANISOTROPY; HELICASES; HEXAMERS; HIGH AFFINITY; MAMMALIAN BRAIN; MITOCHONDRIAL DNA; NEUROMUSCULAR DISEASE; POINT MUTATIONS; REPLICATION FORK; REPLICATION INITIATION; SINGLE-STRANDED (SS) DNA; STRAND ANNEALING;

BINDING SITES; BRAIN; DNA; ESCHERICHIA COLI; MAMMALS; MITOCHONDRIA; NEUROPHYSIOLOGY; OLIGOMERS;

ANNEALING;

DOUBLE STRANDED DNA; HELICASE; OLIGOMER; RECOMBINANT ENZYME; SINGLE STRANDED DNA; TWINKLE HELICASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA BINDING; DNA DENATURATION; DNA STRAND; ENZYME PURIFICATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY;

BINDING SITES; DNA HELICASES; DNA REPAIR; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA, SINGLE-STRANDED; HUMANS; MITOCHONDRIAL PROTEINS; PROTEIN BINDING; RECOMBINANT PROTEINS; URIDINE TRIPHOSPHATE;

ESCHERICHIA COLI; MAMMALIA;

EID: 84860379072     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.309468     Document Type: Article

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