Depression in bipolar disorder versus major depressive disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions

Bipolar Disorders

Volumn 14, Issue 3, 2012, Pages 271-282

  Moreno, Carmen ^a   Hasin, Deborah S ^b,c   Arango, Celso ^a   Oquendo, Maria A ^c   Vieta, Eduard ^d   Liu, Shangmin ^c   Grant, Bridget F ^e   Blanco, Carlos ^c  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b Department of Medicine   (United States)

^c NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Bipolar disorder; Clinical classifications; Depression; Epidemiology

Indexed keywords

PSYCHOTROPIC AGENT;

ADULT; ALCOHOLISM; ANXIETY DISORDER; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CLINICAL FEATURE; COMORBIDITY; DEPRESSION; DISEASE COURSE; DISEASE SEVERITY; DRUG USE; ETHNICITY; FAMILY HISTORY; FEMALE; GENDER; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; PERSONALITY DISORDER; PRIORITY JOURNAL; QUALITY OF LIFE; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; ALCOHOLISM; BIPOLAR DISORDER; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; ETHNIC GROUPS; FEMALE; HEALTH SURVEYS; HUMANS; INTERVIEW, PSYCHOLOGICAL; MALE; MIDDLE AGED; PROBABILITY; PSYCHIATRIC STATUS RATING SCALES; SEVERITY OF ILLNESS INDEX; SEX FACTORS; UNITED STATES; YOUNG ADULT;

EID: 84860366658     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2012.01009.x     Document Type: Article

References (51)

1. Judd LL, Akiskal HS, Schettler PJ et al. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry 2003; 60: 261-269.
2. Judd LL, Akiskal HS, Schettler PJ et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry 2002; 59: 530-537.
3. Rosa AR, Reinares M, Franco C et al. Clinical predictors of functional outcome of bipolar patients in remission. Bipolar Disord 2009; 11: 401-409.
4. Marangell LB, Bauer MS, Dennehy EB et al. Prospective predictors of suicide and suicide attempts in 1, 556 patients with bipolar disorders followed for up to 2years. Bipolar Disord 2006; 8: 566-575.
5. Mitchell PB, Goodwin GM, Johnson GF, Hirschfeld RMA. Diagnostic guidelines for bipolar depression: a probabilistic approach. Bipolar Disord 2008; 10: 144-152.
6. Mitchell PB, Malhi GS. Bipolar depression: phenomenological overview and clinical characteristics. Bipolar Disord 2004; 6: 530-539.
7. Bowden CL. A different depression: clinical distinctions between bipolar and unipolar depression. J Affect Disord 2005; 84: 117-125.
8. Muzina DJ, Kemp DE, McIntyre RS. Differentiating bipolar disorders from major depressive disorders: treatment implications. Ann Clin Psychiatry 2007; 19: 305-312.
9. Benazzi F. Clinical differences between bipolar II depression and unipolar major depressive disorder: lack of an effect of age. J Affect Disord 2003; 75: 191-195.
10. Benazzi F. Psychomotor changes in melancholic and atypical depression: unipolar and bipolar-II subtypes. Psychiatry Res 2002; 112: 211-220.
11. Hantouche EG, Akiskal HS. Bipolar II vs. unipolar depression: psychopathologic differentiation by dimensional measures. J Affect Disord 2005; 84: 127-132.
12. Brugue E, Colom F, Sanchez-Moreno J, Cruz N, Vieta E. Depression subtypes in bipolar I and II disorders. Psychopathology 2008; 41: 111-114.
13. Mitchell PB, Wilhelm K, Parker G, Austin MP, Rutgers P, Malhi GS. The clinical features of bipolar depression: a comparison with matched major depressive disorder patients. J Clin Psychiatry 2001; 62: 212-216.
14. Mitchell P, Parker G, Jamieson K et al. Are there any differences between bipolar and unipolar melancholia? J Affect Disord 1992; 25: 97-105.
15. Furukawa TA, Konno W, Morinobu S, Harai H, Kitamura T, Takahashi K. Course and outcome of depressive episodes: comparison between bipolar, unipolar and subthreshold depression. Psychiatry Res 2000; 96: 211-220.
16. Parker G, Roy K, Wilhelm K, Mitchell P, Hadzi-Pavlovic D. The nature of bipolar depression: implications for the definition of melancholia. J Affect Disord 2000; 59: 217-224.
17. Olfson M, Das AK, Gameroff MJ et al. Bipolar depression in a low-income primary care clinic. Am J Psychiatry 2005; 162: 2146-2151.
18. Perlis RH, Brown E, Baker RW, Nierenberg AA. Clinical features of bipolar depression versus major depressive disorder in large multicenter trials. Am J Psychiatry 2006; 163: 225-231.
19. Solomon DA, Leon AC, Maser JD et al. Distinguishing bipolar major depression from unipolar major depression with the screening assessment of depression-polarity (SAD-P). J Clin Psychiatry 2006; 67: 434-442.
20. Serretti A, Mandelli L, Lattuada E, Cusin C, Smeraldi E. Clinical and demographic features of mood disorder subtypes. Psychiatry Res 2002; 112: 195-210.
21. Phillips ML, Vieta E. Identifying functional neuroimaging biomarkers of bipolar disorder: toward DSM-V. Schizophr Bull 2007; 33: 893-904.
22. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association, 1994.
23. Benazzi F. Bipolar versus unipolar psychotic outpatient depression. J Affect Disord 1999; 55: 63-66.
24. Parsey RV, Hastings RS, Oquendo MA et al. Lower serotonin transporter binding potential in the human brain during major depressive episodes. Am J Psychiatry 2006; 163: 52-58.
25. Konarski JZ, McIntyre RS, Kennedy SH, Rafi-Tari S, Soczynska JK, Ketter TA. Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder. Bipolar Disord 2008; 10: 1-37.
26. Grant BF, Dawson DA, Stinson FS, Chou PS, Kay W, Pickering R. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug Alcohol Depend 2003; 71: 7-16.
27. Grant BF, Dawson DA, Hasin DS. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-IV Version. Bethesda: National Institute on Alcohol Abuse and Alcoholism, 2001.
28. Williams JB, Gibbon M, First MB et al. The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability. Arch Gen Psychiatry 1992; 49: 630-636.
29. Canino G, Bravo M, Ramirez R et al. The Spanish Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): reliability and concordance with clinical diagnoses in a Hispanic population. J Stud Alcohol 1999; 60: 790-799.
30. Wittchen HU, Lachner G, Wunderlich U, Pfister H. Test-retest reliability of the computerized DSM-IV version of the Munich-Composite International Diagnostic Interview (M-CIDI). Soc Psychiatry Psychiatr Epidemiol 1998; 33: 568-578.
31. Simpson SG, McMahon FJ, McInnis MG et al. Diagnostic reliability of bipolar II disorder. Arch Gen Psychiatry 2002; 59: 736-740.
32. Ware JE, Kosinski M, Turner-Bowker DM, Gandek B. How to Score Version 2 of the SF-12 Health Survey. Lincoln: Quality Metrics, 2002.
33. Hasin DS, Goodwin RD, Stinson FS, Grant BF. Epidemiology of major depressive disorder: results from the National Epidemiologic Survey on Alcoholism and Related Conditions. Arch Gen Psychiatry 2005; 62: 1097-1106.
34. Grant BF, Stinson FS, Hasin DS et al. Prevalence, correlates, and comorbidity of bipolar I disorder and Axis I and II disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2005; 66: 1205-1215.
35. World Health Organization. International Statistical Classification of Diseases and Related Health Problems 10th Revision Version for 2007. Available from: Last accessed August 11, 2011.
36. Brennan PA, Hammen C, Andersen MJ, Bor W, Najman JM, Williams GM. Chronicity, severity, and timing of maternal depressive symptoms: relationships with child outcomes at age 5. Dev Psychol 2000; 36: 759-766.
37. Research Triangle Institute. Software for Survey Data Analysis (SUDAAN) Version 9.0. Research Triangle Park: Research Triangle Institute, 2004.
38. Benazzi F. Symptoms of depression as possible markers of bipolar II disorder. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30: 471-477.
39. Wilens TE, Biederman J, Adamson J et al. Association of bipolar and substance use disorders in parents of adolescents with bipolar disorder. Biol Psychiatry 2007; 62: 129-134.
40. Coryell W, Solomon DA, Fiedorowicz JG, Endicott J, Schettler PJ, Judd LL. Anxiety and outcome in bipolar disorder. Am J Psychiatry 2009; 166: 1238-1243.
41. Regier DA, Farmer ME, Rae DS et al. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA 1990; 264: 2511-2518.
42. American Psychiatric Association. DSM-V Development. Available from: Last accessed August 11, 2011.
43. Schaffer A, Cairney J, Veldhuizen S, Kurdyak P, Cheung A, Levitt A. A population-based analysis of distinguishers of bipolar disorder from major depressive disorder. J Affect Disord 2010; 125: 103-110.
44. Vieta E, Phillips ML. Deconstructing bipolar disorder: a critical review of its diagnostic validity and a proposal for DSM-V and ICD-11. Schizophr Bull 2007; 33: 886-892.
45. Cassano GB, Rucci P, Frank E et al. The mood spectrum in unipolar and bipolar disorder: arguments for a unitary approach. Am J Psychiatry 2004; 161: 1264-1269.
46. Goldberg JF, Perlis RH, Bowden CL et al. Manic symptoms during depressive episodes in 1, 380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry 2009; 166: 173-181.
47. NIMH Website. Available from Last accessed August 11, 2011.
48. Kessler RC, Berglund P, Demler O et al. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003; 289: 3095-3105.
49. Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005; 62: 593-602.
50. Kessler RC, Akiskal HS, Angst J et al. Validity of the assessment of bipolar spectrum disorders in the WHO CIDI 3.0. J Affect Disord 2006; 96: 259-269.
51. Merikangas KR, Akiskal HS, Angst J et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 2007; 64: 543-552.