Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility

Experimental Physiology

Volumn 97, Issue 5, 2012, Pages 583-602

  Amobi, Nnaemeka I B ^a,b   Guillebaud, John ^b   Smith, I Christopher H ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 BENZYLBENZOYL) 2,5 DIMETHYL 1H PYRROLE 3 CARBOXYLIC ACID METHYL ESTER; 4 AMINOPYRIDINE; APAMIN; CALCIUM CHANNEL; IBERIOTOXIN; NORADRENALIN; POTASSIUM CHANNEL; PURINERGIC P2X RECEPTOR; RHO KINASE;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LONGITUDINAL MUSCLE; LONGITUDINAL MUSCLE CONTRACTION; MALE; MUSCLE CONTRACTION; MUSCLE FIBER MEMBRANE CONDUCTANCE; MUSCLE FUNCTION; MUSCLE TYPE ACCORDING TO FUNCTION; NORMAL HUMAN; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE CONTRACTION; VAS DEFERENS;

EID: 84860343595     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2011.063206     Document Type: Article

References (87)

1. Allcorn RJ, Cunnane TC & Kirkpatrick K (1986). Actions of α, β-methylene ATP and 6-hydroxydopamine on sympathetic neurotransmission in the vas deferens of the guinea-pig, rat and mouse: support for cotransmission. Br J Pharmacol 89, 647-659.
2. Alm P (1982). On the autonomic innervation of the human vas deferens. Brain Res Bull 9, 673-677.
3. 1-purinoceptor agonists in human vas deferens. Proc Physiol Soc 25, PC41.
4. Amobi NIB, Chung I-P & Smith ICH (2006). Attenuation of contractility in rat epididymal vas deferens by Rho kinase inhibitors. Auton Autacoid Pharmacol 26, 169-181.
5. Amobi NIB & Smith ICH (1998). Electromechanical coupling in human vas deferens: effects of agents that modulate intracellular release of calcium. J Auton Pharmacol 18, 157-165.
6. Anton PG & McGrath JC (1977). Further evidence for adrenergic transmission in the human vas deferens. J Physiol 273, 45-55.
7. Banks FC, Knight GE, Calvert RC, Thompson CS, Morgan RJ & Burnstock G (2006). The purinergic component of human vas deferens contraction. Fertil Steril 85, 932-939.
8. Bao JX, Eriksson IE & Stjaèrne L (1990). Neurotransmitters and pre- and postjunctional receptors involved in the vasoconstrictor response to sympathetic nerve stimulation in rat tail artery. Acta Physiol Scand 140, 467-479.
9. Bao JX & Stjaèrne L (1993). Dual contractile effects of ATP released by field stimulation revealed by effects of α, β-methylene ATP and suramin in rat tail artery. Br J Pharmacol 110, 1421-1428.
10. Benham CD (1990). ATP-gated channels in vascular smooth muscle cells. Ann N Y Acad Sci 603, 275-286.
11. Birmingham AT (1968). The human isolated vas deferens: its response to electrical stimulation and to drugs. Br J Pharmacol 34, 692P.
12. 2+ transients in the mouse vas deferens. J Physiol 553, 627-635.
13. Brozovich FV (2003). Rho signaling: agonist stimulation and depolarization come together. Circ Res 93, 481-483.
14. 1A-adrenoceptor-mediated contraction to noradrenaline of rat isolated epididymal vas deferens. Br J Pharmacol 117, 224-230.
15. 2+ influx stimulated by diacylglycerol and PKC. Br J Pharmacol 123, 317-325.
16. Büyükafşar K, Levent A & Ark M (2003). Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens. Br J Pharmacol 140, 743-749.
17. Chin PF & Pennefather JN (1988). Evidence that ATP does not act as a cotransmitter with noradrenaline in field-stimulated preparations of rat seminal vesicles. Eur J Pharmacol 155, 309-312.
18. Crack BE, Pollard CE, Beukers MW, Roberts SM, Hunt SF, Ingall AH, McKechnie KC, Ijzerman AP & Leff P (1995). Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase. Br J Pharmacol 114, 475-481.
19. + channel blockers in rat vas deferens. Eur J Pharmacol 287, 287-293.
20. Durlu-Kandilci T & Brading AF (2006). Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in β-escin skinned rat and guinea-pig bladders. Br J Pharmacol 148, 376-384.
21. Eglen RM, Hegde SS & Watson N (1996). Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev 48, 531-565.
22. Faber ES & Sah P (2003). Calcium-activated potassium channels: multiple contributions to neuronal function. Neuroscientist 9, 181-194.
23. Fedan JS, Hogaboom KG, Westfall DP & O'Donnell JP (1982). Comparison of contractions of the smooth muscle of the guinea-pig vas deferens induced by ATP and related nucleotides. Eur J Pharmacol 81, 193-204.
24. Fedan JS & Lamport SJ (1990). Two dissociable phases in the contractile response of the guinea pig isolated vas deferens to adenosine triphosphate. J Pharmacol Exp Ther 253, 993-1001.
25. Felder CC (1995). Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 9, 619-625.
26. 2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction. Circ Res 108, 1348-1357.
27. Friel DD (1988). An ATP-sensitive conductance in single smooth muscle cells from the rat vas deferens. J Physiol 401, 361-380.
28. 2+ sensitization of skinned muscle of guinea pig vas deferens. J Pharmacol Exp Ther 274, 555-561.
29. Hedlund H, Andersson K-E & Larsson B (1985). Effect of drugs interacting with adrenoreceptors and muscarinic receptors in the epididymal and prostatic parts of the human isolated vas deferens. J Auton Pharmacol 5, 261-270.
30. + channels regulate action potential repolarization in urinary bladder smooth muscle. Am J Physiol Cell Physiol 273, C110-C117.
31. 2+ transients evoked by nerve stimulation in rat urinary bladder smooth muscle. J Physiol 564, 201-212.
32. 2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle. J Physiol 587, 5275-5288.
33. Ca channels in urinary bladder smooth muscle. Am J Physiol Cell Physiol 280, C481-C490.
34. 2+ channels and ryanodine receptors in guinea-pig urinary bladder myocytes. J Physiol 541, 483-492.
35. 2+ signaling networks. J Gen Physiol 136, 149-154.
36. Holmquist F, Hedlund H & Andersson KE (1990). Effects of the α1-adrenoceptor antagonist R-(-)-YM12617 on isolated human penile erectile tissue and vas deferens. Eur J Pharmacol 186, 87-93.
37. Hoyle CHV, Knight GE & Burnstock G (1990). Suramin antagonizes responses to P2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli. Br J Pharmacol 99, 617-621.
38. + channel and its functional roles in smooth muscle cells of guinea pig taenia coli. J Gen Physiol 94, 833-847.
39. 2- and 4-aminopyridine-evoked phasic contractions in the rat vas deferens. Br J Pharmacol 115, 845-851.
40. Iqbal J, Vollmayer P, Braun N, Zimmermann H & Müller CE (2005). A capillary electrophoresis method for the characterization of ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) and the analysis of inhibitors by in-capillary enzymatic microreaction. Purinergic Signal 1, 349-358.
41. Jaggar JH, Porter VA, Lederer WJ & Nelson MT (2000). Calcium sparks in smooth muscle. Am J Physiol Cell Physiol 278, C235-C256.
42. + channels: a functional unit for regulating arterial tone. Acta Physiol Scand 164, 577-587.
43. Johns A, Golko DS, Lauzon PA & Paton DM (1976). The potentiating effects of 4-aminopyridine on adrenergic transmission in the rabbit vas deferens. Eur J Pharmacol 38, 71-78.
44. Kazic T & Milosavljevic D (1980). Interaction between adenosine triphosphate and noradrenaline in the isolated vas deferens of the guinea-pig. Br J Pharmacol 71, 93-98.
45. Klöckner U & Isenberg G (1985). Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig). Pflugers Arch 405, 329-339.
46. 2+ and voltage. Biol Res 39, 385-401.
47. Ledoux J, Werner ME, Brayden JE & Nelson MT (2006). Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) 21, 69-78.
48. Lee HY, Bardini M & Burnstock G (2000). P2X receptor immunoreactivity in the male genital organs of the rat. Cell Tissue Res 300, 321-330.
49. Lévesque SA, Lavoie EG, Lecka J, Bigonnesse F & Sévigny J (2007). Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases. Br J Pharmacol 152, 141-150.
50. 2+ microdomains in smooth muscle. Cell Calcium 40, 461-493.
51. 2x-purinoceptors to neurotransmission in several rabbit isolated blood vessels: role of neuronal uptake and autofeedback. Br J Pharmacol 105, 347-354.
52. Medina P, Segarra G, Chuan P, Domenech C, Vila JM, Aldasoro M & Lluch S (1998). Vasopressin receptors involved in adrenergic neurotransmission in the circular muscle of the human vas deferens. Eur J Pharmacol 355, 41-49.
53. 2-induced inhibition of the adrenergic response in human vas deferens. Biochem Pharmacol 82, 65-71.
54. + channel inhibitors. Urology 76, 1518.e7-1518.e12.
55. Medina P, Segarra G, Torondel B, Chuan P, Domenech C, Vila JM & Lluch S (2000). Inhibition of neuroeffector transmission in human vas deferens by sildenafil. Br J Pharmacol 131, 871-874.
56. Meldrum LA & Burnstock G (1983). Evidence that ATP acts as a co-transmitter with noradrenaline in sympathetic nerves supplying the guinea-pig vas deferens. Eur J Pharmacol 92, 161-163.
57. Müller CE, Iqbal J, Baqi Y, Zimmermann H, Röllich A & Stephan H (2006). Polyoxometalates-a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett 16, 5943-5947.
58. 1 receptors. Nature 403, 86-89.
59. 2+ transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder. J Physiol 534, 313-326.
60. + channels in rabbit aorta and vas deferens smooth muscle. Pflugers Arch 441, 611-620.
61. Park SY, Lee MY, Keum EM, Myung SC & Kim SC (2004). Ionic currents in single smooth muscle cells of the human vas deferens. J Urol 172, 628-633.
62. 2-purinoceptor agonists by a purified ectonucleotidase from the bovine aorta, the ATP-diphosphohydrolase. Biochem Pharmacol 51, 1453-1460.
63. 2+ signaling in smooth muscle: why two membranes are better than one. Trends Pharmacol Sci 25, 8-15.
64. Ren LM, Hoyle CH & Burnstock G (1996). Developmental changes in sympathetic contraction of the circular muscle layer in the guinea-pig vas deferens. Eur J Pharmacol 318, 411-417.
65. 2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction. Circ Res 93, 548-556.
66. Sanger GJ, Ellis ES, Harries MH, Tilford NS, Wardle KA & Benham CD (2000). Rank-order inhibition by ω-conotoxins in human and animal autonomic nerve preparations. Eur J Pharmacol. 388, 89-95.
67. 2+-dependent and ####independent mechanisms. J Physiol 560, 839-855.
68. Sneddon P & Burnstock G (1984). Inhibition of excitatory junction potentials in guinea-pig vas deferens by α, β-methylene-ATP: further evidence for ATP and noradrenaline as cotransmitters. Eur J Pharmacol 100, 85-90.
69. Sneddon P, Westfall TD, Todorov LD, Todorova SM, Westfall DP, Nickel P & Kennedy C (2000). The effect of P2 receptor antagonists and ATPase inhibition on sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens. Br J Pharmacol 129, 1089-1094.
70. Stjärne L (2001). Novel dual 'small' vesicle model of ATP- and noradrenaline-mediated sympathetic neuromuscular transmission. Auton Neurosci 87, 16-36.
71. Stjärne L & Åstrand P (1984). Relative pre- and postjunctional roles of noradrenaline and adenosine 5′-triphosphate as neurotransmitters of the sympathetic nerves of guinea-pig and mouse vas deferens. Neuroscience 14, 929-946.
72. Stjärne L & Stjärne E (1997). Electrophysiological evidence that the twitch contraction of guinea-pig vas deferens is triggered by phasic activation of P2x-purinoceptors. Acta Physiol Scand 160, 295-296.
73. 3H-adenosine triphosphate release during stimulation of enteric nerves. Science 173, 336-339.
74. Summers RJ. & McMartin LR (1993). Adrenoceptors and their second messenger systems. J Neurochem 60, 10-23.
75. Todorov LD, Bjur RA & Westfall DP (1994). Temporal dissociation of the release of the sympathetic cotransmitters ATP and noradrenaline. Clin Exp Pharmacol Physiol 21, 931-932.
76. Todorov LD, Mihaylova-Todorova ST, Bjur RA & Westfall DP (1999). Differential cotransmission in sympathetic nerves: role of frequency of stimulation and prejunctional autoreceptors. J Pharmacol Exp Ther 290, 241-246.
77. Todorov LD, Mihaylova-Todorova S, Craviso GL, Bjur RA & Westfall DP (1996). Evidence for the differential release of the cotransmitters ATP and noradrenaline from sympathetic nerves of the guinea-pig vas deferens. J Physiol 496, 731-748.
78. 2+ sensitization of arterial muscle. Am J Physiol Cell Physiol 285, C1377-C1385.
79. Vial C & Evans RJ (2001). Smooth muscle does not have a common P2x receptor phenotype: expression, ontogeny and function of P2x1 receptors in mouse ileum, bladder and reproductive systems. Auton Neurosci 92, 56-64.
80. 2+-sensitive ion channels. Cell Calcium 34, 211-229.
81. Werner ME, Knorn AM, Meredith AL, Aldrich RW & Nelson MT (2007). Frequency encoding of cholinergic- and purinergic-mediated signaling to mouse urinary bladder smooth muscle: modulation by BK channels. Am J Physiol Regul Integr Comp Physiol 292, R616-R624.
82. Westfall TD, Kennedy C & Sneddon P (1996a). Enhancement of sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens by the novel ecto-ATPase inhibitor ARL 67156. Br J Pharmacol 117, 867-872.
83. Westfall DP, Todorov LD, Mihaylova-Todorova ST & Bjur RA (1996b). Differences between the regulation of noradrenaline and ATP release. J Auton Pharmacol 16, 393-395.
84. Wibberley A, Chen Z, Hu E, Hieble JP & Westfall TD (2003). Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol 138, 757-766.
85. Yeoh M & Brock JA (2005). Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro. Br J Pharmacol 146, 854-861.
86. 2+ channel activator, in cardiac and vascular preparations. Mol Pharmacol 40, 734-741.
87. 2+ spark. J Gen Physiol 120, 15-27.