-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
PMID:21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
39449096135
-
Genome instability: A mechanistic view of its causes and consequences
-
PMID:18227811
-
Aguilera A, Gómez-González B. Genome instability: a mechanistic view of its causes and consequences. Nat Rev Genet 2008; 9:204-17; PMID:18227811; http://dx.doi.org/10.1038/nrg2268.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 204-217
-
-
Aguilera, A.1
Gómez-González, B.2
-
3
-
-
71149093724
-
How telomeres solve the end-protection problem
-
PMID:19965504
-
de Lange T. How telomeres solve the end-protection problem. Science 2009; 326:948-52; PMID:19965504; http://dx.doi.org/10.1126/science.1170633.
-
(2009)
Science
, vol.326
, pp. 948-952
-
-
De Lange, T.1
-
4
-
-
77649180958
-
Telomeres: Protecting chromosomes against genome instability
-
PMID:20125188
-
O'Sullivan RJ, Karlseder J. Telomeres: protecting chromosomes against genome instability. Nat Rev Mol Cell Biol 2010; 11:171-81; PMID:20125188.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 171-181
-
-
O'Sullivan, R.J.1
Karlseder, J.2
-
5
-
-
80052398381
-
How shelterin solves the telomere end-protection problem
-
PMID:21209389
-
de Lange T. How shelterin solves the telomere end-protection problem. Cold Spring Harb Symp Quant Biol 2010; 75:167-77; PMID:21209389; http://dx.doi.org/10.1101/sqb.2010.75.017.
-
(2010)
Cold Spring Harb Symp Quant Biol
, vol.75
, pp. 167-177
-
-
De Lange, T.1
-
6
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
PMID:2342578
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990; 345:458-60; PMID:2342578; http://dx.doi.org/10. 1038/345458a0.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
7
-
-
80054029091
-
The causes and consequences of polyploidy in normal development and cancer
-
PMID:21801013
-
Davoli T, de Lange T. The causes and consequences of polyploidy in normal development and cancer. Annu Rev Cell Dev Biol 2011; 27:585-610; PMID:21801013; http://dx.doi.org/10.1146/annurev-cellbio-092910-154234.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 585-610
-
-
Davoli, T.1
De Lange, T.2
-
8
-
-
78349270933
-
Role of shelterin in cancer and aging
-
PMID:20569239
-
Martínez P, Blasco MA. Role of shelterin in cancer and aging. Aging Cell 2010; 9:653-66; PMID:20569239; http://dx.doi.org/10.1111/j.1474-9726. 2010.00596.x.
-
(2010)
Aging Cell
, vol.9
, pp. 653-666
-
-
Martínez, P.1
Blasco, M.A.2
-
9
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
PMID:14608368
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003; 426:194-8; PMID:14608368; http://dx.doi.org/10.1038/ nature02118.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
D'Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
-
10
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
PMID:12956959
-
Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003; 13:1549-56; PMID:12956959; http://dx.doi.org/10.1016/ S0960-9822(03)00542-6.
-
(2003)
Curr Biol
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
De Lange, T.3
-
11
-
-
11144268164
-
INK4a in p53-independent telomere-directed senescence
-
PMID:15620660
-
INK4ain p53-independent telomere-directed senescence. Curr Biol 2004; 14:2302-8; PMID:15620660; http://dx.doi.org/10.1016/j.cub.2004.12.025.
-
(2004)
Curr Biol
, vol.14
, pp. 2302-2308
-
-
Jacobs, J.J.1
De Lange, T.2
-
12
-
-
74049111326
-
Telomeres and telomerase in cancer
-
PMID:19887512
-
Artandi SE, DePinho RA. Telomeres and telomerase in cancer. Carcinogenesis 2010; 31:9-18; PMID:19887512; http://dx.doi.org/10.1093/carcin/ bgp268.
-
(2010)
Carcinogenesis
, vol.31
, pp. 9-18
-
-
Artandi, S.E.1
DePinho, R.A.2
-
13
-
-
79952017845
-
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins
-
PMID:21346783
-
Martínez P, Blasco MA. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nat Rev Cancer 2011; 11:161-76; PMID:21346783; http://dx.doi.org/10.1038/nrc3025.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 161-176
-
-
Martínez, P.1
Blasco, M.A.2
-
14
-
-
80053555789
-
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
-
PMID:21968989
-
Lukas J, Lukas C, Bartek J. More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol 2011; 13:1161-9; PMID:21968989; http://dx.doi.org/10.1038/ncb2344.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1161-1169
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
15
-
-
80052491304
-
DNA-damage response and repair activities at uncapped telomeres depend on RNF8
-
PMID:21857671
-
Peuscher MH, Jacobs JJ. DNA-damage response and repair activities at uncapped telomeres depend on RNF8. Nat Cell Biol 2011; 13:1139-45; PMID:21857671; http://dx.doi.org/10.1038/ncb2326.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1139-1145
-
-
Peuscher, M.H.1
Jacobs, J.J.2
-
16
-
-
77955841722
-
Structural identity of telomeric complexes
-
PMID:20696167
-
Giraud-Panis MJ, Pisano S, Poulet A, Le Du MH, Gilson E. Structural identity of telomeric complexes. FEBS Lett 2010; 584:3785-99; PMID:20696167; http://dx.doi.org/10.1016/j.febslet.2010.08.004.
-
(2010)
FEBS Lett
, vol.584
, pp. 3785-3799
-
-
Giraud-Panis, M.J.1
Pisano, S.2
Poulet, A.3
Le Du, M.H.4
Gilson, E.5
-
17
-
-
33947317206
-
The epigenetic regulation of mammalian telomeres
-
PMID:17363977
-
Blasco MA. The epigenetic regulation of mammalian telomeres. Nat Rev Genet 2007; 8:299-309; PMID:17363977; http://dx.doi.org/10.1038/nrg2047.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 299-309
-
-
Blasco, M.A.1
-
18
-
-
80052468708
-
A role for heterochromatin protein 1γ at human telomeres
-
PMID:21865325
-
Canudas S, Houghtaling BR, Bhanot M, Sasa G, Savage SA, Bertuch AA, et al. A role for heterochromatin protein 1γ at human telomeres. Genes Dev 2011; 25:1807-19; PMID:21865325; http://dx.doi.org/10.1101/gad.17325211.
-
(2011)
Genes Dev
, vol.25
, pp. 1807-1819
-
-
Canudas, S.1
Houghtaling, B.R.2
Bhanot, M.3
Sasa, G.4
Savage, S.A.5
Bertuch, A.A.6
-
19
-
-
77952318828
-
The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility
-
PMID:20056655
-
Pisano S, Leoni D, Galati A, Rhodes D, Savino M, Cacchione S. The human telomeric protein hTRF1 induces telomere-specific nucleosome mobility. Nucleic Acids Res 2010; 38:2247-55; PMID:20056655; http://dx.doi.org/10.1093/nar/ gkp1228.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2247-2255
-
-
Pisano, S.1
Leoni, D.2
Galati, A.3
Rhodes, D.4
Savino, M.5
Cacchione, S.6
-
20
-
-
0027212790
-
Nucleosomal organization of telomere-specific chromatin in rat
-
PMID:8500170
-
Makarov VL, Lejnine S, Bedoyan J, Langmore JP. Nucleosomal organization of telomere-specific chromatin in rat. Cell 1993; 73:775-87; PMID:8500170; http://dx.doi.org/10.1016/0092-8674(93)90256-P.
-
(1993)
Cell
, vol.73
, pp. 775-787
-
-
Makarov, V.L.1
Lejnine, S.2
Bedoyan, J.3
Langmore, J.P.4
-
21
-
-
0028928198
-
Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes
-
PMID:7892278
-
Lejnine S, Makarov VL, Langmore JP. Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes. Proc Natl Acad Sci USA 1995; 92:2393-7; PMID:7892278; http://dx.doi.org/10.1073/pnas.92.6.2393.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2393-2397
-
-
Lejnine, S.1
Makarov, V.L.2
Langmore, J.P.3
-
22
-
-
51349167747
-
No overt nucleosome eviction at deprotected telomeres
-
PMID:18625717
-
Wu P, de Lange T. No overt nucleosome eviction at deprotected telomeres. Mol Cell Biol 2008; 28:5724-35; PMID:18625717; http://dx.doi.org/10.1128/MCB. 01764-07.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5724-5735
-
-
Wu, P.1
De Lange, T.2
-
23
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
PMID:3907856
-
Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43:405-13; PMID:3907856; http://dx.doi.org/10.1016/0092-8674(85)90170-9.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
24
-
-
79955774048
-
Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells
-
PMID:21222203
-
Marión RM, Blasco MA. Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells. Adv Exp Med Biol 2010; 695:118-31; PMID:21222203; http://dx.doi.org/10.1007/978-1-4419-7037-4-9.
-
(2010)
Adv Exp Med Biol
, vol.695
, pp. 118-131
-
-
Marión, R.M.1
Blasco, M.A.2
-
25
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
PMID:9454332
-
Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, et al. Extension of life-span by introduction of telomerase into normal human cells. Science 1998; 279:349-52; PMID:9454332; http://dx.doi.org/10.1126/science.279. 5349.349.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
-
26
-
-
39749163359
-
Telomerase and cancer therapeutics
-
PMID:18256617
-
Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008; 8:167-79; PMID:18256617; http://dx.doi.org/10.1038/nrc2275.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 167-179
-
-
Harley, C.B.1
-
27
-
-
77951133257
-
Alternative lengthening of telomeres: Models, mechanisms and implications
-
PMID:20351727
-
Cesare AJ, Reddel RR. Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 2010; 11:319-30; PMID:20351727; http://dx.doi.org/10.1038/nrg2763.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 319-330
-
-
Cesare, A.J.1
Reddel, R.R.2
-
28
-
-
80052069445
-
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
-
PMID:21863050
-
Lipkowitz S, Weissman AM. RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis. Nat Rev Cancer 2011; 11:629-43; PMID:21863050; http://dx.doi.org/10.1038/nrc3120.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 629-643
-
-
Lipkowitz, S.1
Weissman, A.M.2
-
29
-
-
80052697814
-
The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
-
PMID:21664912
-
Bekker-Jensen S, Mailand N. The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks. FEBS Lett 2011; 585:2914-9; PMID:21664912; http://dx.doi.org/10.1016/j.febslet.2011.05.056.
-
(2011)
FEBS Lett
, vol.585
, pp. 2914-2919
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
30
-
-
79960046164
-
Cellular stress response pathways and ageing: Intricate molecular relationships
-
PMID:21587205
-
Kourtis N, Tavernarakis N. Cellular stress response pathways and ageing: intricate molecular relationships. EMBO J 2011; 30:2520-31; PMID:21587205; http://dx.doi.org/10.1038/emboj.2011.162.
-
(2011)
EMBO J
, vol.30
, pp. 2520-2531
-
-
Kourtis, N.1
Tavernarakis, N.2
-
31
-
-
80053445278
-
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae
-
PMID:21931558
-
Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, et al. Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet 2011; 7:1002253; PMID:21931558; http://dx.doi.org/10. 1371/journal.pgen.1002253.
-
(2011)
PLoS Genet
, vol.7
, pp. 1002253
-
-
Kruegel, U.1
Robison, B.2
Dange, T.3
Kahlert, G.4
Delaney, J.R.5
Kotireddy, S.6
-
32
-
-
80655123583
-
CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination
-
PMID:22032989
-
Latini P, Frontini M, Caputo M, Gregan J, Cipak L, Filippi S, et al. CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination. Cell Cycle 2011; 10:3719-30; PMID:22032989; http://dx.doi.org/ 10.4161/cc.10.21.17905.
-
(2011)
Cell Cycle
, vol.10
, pp. 3719-3730
-
-
Latini, P.1
Frontini, M.2
Caputo, M.3
Gregan, J.4
Cipak, L.5
Filippi, S.6
-
33
-
-
72949123930
-
The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair
-
PMID:19965384
-
Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, et al. The Fanconi anemia pathway promotes replication- dependent DNA interstrand cross-link repair. Science 2009; 326:1698-701; PMID:19965384; http://dx.doi.org/10.1126/science.1182372.
-
(2009)
Science
, vol.326
, pp. 1698-1701
-
-
Knipscheer, P.1
Räschle, M.2
Smogorzewska, A.3
Enoiu, M.4
Ho, T.V.5
Schärer, O.D.6
-
34
-
-
80052434889
-
Human telomerase activity regulation
-
PMID:21086176
-
Wojtyla A, Gladych M, Rubis B. Human telomerase activity regulation. Mol Biol Rep 2011; 38:3339-49; PMID:21086176; http://dx.doi.org/10.1007/s11033-010- 0439-x.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 3339-3349
-
-
Wojtyla, A.1
Gladych, M.2
Rubis, B.3
-
35
-
-
17044367499
-
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT
-
PMID:15805468
-
Kim JH, Park SM, Kang MR, Oh SY, Lee TH, Muller MT, et al. Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev 2005; 19:776-81; PMID:15805468; http://dx.doi.org/10.1101/gad. 1289405.
-
(2005)
Genes Dev
, vol.19
, pp. 776-781
-
-
Kim, J.H.1
Park, S.M.2
Kang, M.R.3
Oh, S.Y.4
Lee, T.H.5
Muller, M.T.6
-
36
-
-
77954759082
-
Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT
-
PMID:20453884
-
Oh W, Lee EW, Lee D, Yang MR, Ko A, Yoon CH, et al. Hdm2 negatively regulates telomerase activity by functioning as an E3 ligase of hTERT. Oncogene 2010; 29:4101-12; PMID:20453884; http://dx.doi.org/10.1038/onc.2010.160.
-
(2010)
Oncogene
, vol.29
, pp. 4101-4112
-
-
Oh, W.1
Lee, E.W.2
Lee, D.3
Yang, M.R.4
Ko, A.5
Yoon, C.H.6
-
37
-
-
78650632231
-
CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity
-
PMID:20959453
-
Lee JH, Khadka P, Baek SH, Chung IK. CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity. J Biol Chem 2010; 285:42033-45; PMID:20959453; http://dx.doi.org/10.1074/jbc. M110.149831.
-
(2010)
J Biol Chem
, vol.285
, pp. 42033-42045
-
-
Lee, J.H.1
Khadka, P.2
Baek, S.H.3
Chung, I.K.4
-
38
-
-
77955871461
-
The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor
-
PMID:20679392
-
Manfredi JJ. The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. Genes Dev 2010; 24:1580-9; PMID:20679392; http://dx.doi.org/10.1101/gad.1941710.
-
(2010)
Genes Dev
, vol.24
, pp. 1580-1589
-
-
Manfredi, J.J.1
-
39
-
-
79954930813
-
Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis
-
PMID:21272160
-
Xu T, Zhou Q, Zhou J, Huang Y, Yan Y, Li W, et al. Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis. Cancer Sci 2011; 102:959-66; PMID:21272160; http://dx.doi.org/10.1111/j.1349-7006. 2011.01888.x.
-
(2011)
Cancer Sci
, vol.102
, pp. 959-966
-
-
Xu, T.1
Zhou, Q.2
Zhou, J.3
Huang, Y.4
Yan, Y.5
Li, W.6
-
40
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
PMID:9034193
-
van Steensel B, de Lange T. Control of telomere length by the human telomeric protein TRF1. Nature 1997; 385:740-3; PMID:9034193; http://dx.doi.org/10.1038/385740a0.
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
Van Steensel, B.1
De Lange, T.2
-
41
-
-
0037610123
-
TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres
-
PMID:12782650
-
Chang W, Dynek JN, Smith S. TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres. Genes Dev 2003; 17:1328-33; PMID:12782650; http://dx.doi.org/10.1101/gad.1077103.
-
(2003)
Genes Dev
, vol.17
, pp. 1328-1333
-
-
Chang, W.1
Dynek, J.N.2
Smith, S.3
-
42
-
-
33644855565
-
The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance
-
PMID:16275645
-
Lee TH, Perrem K, Harper JW, Lu KP, Zhou XZ. The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance. J Biol Chem 2006; 281:759-68; PMID:16275645; http://dx.doi.org/10. 1074/jbc.M509855200.
-
(2006)
J Biol Chem
, vol.281
, pp. 759-768
-
-
Lee, T.H.1
Perrem, K.2
Harper, J.W.3
Lu, K.P.4
Zhou, X.Z.5
-
43
-
-
76249092490
-
Structural basis of selective ubiquitination of TRF1 by SCFFbx4
-
PMID:20159592
-
Zeng Z, Wang W, Yang Y, Chen Y, Yang X, Diehl JA, et al. Structural basis of selective ubiquitination of TRF1 by SCFFbx4. Dev Cell 2010; 18:214-25; PMID:20159592; http://dx.doi.org/10.1016/j.devcel.2010.01.007.
-
(2010)
Dev Cell
, vol.18
, pp. 214-225
-
-
Zeng, Z.1
Wang, W.2
Yang, Y.3
Chen, Y.4
Yang, X.5
Diehl, J.A.6
-
44
-
-
67649763465
-
Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1
-
PMID:19164295
-
Her YR, Chung IK. Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1. J Biol Chem 2009; 284:8557-66; PMID:19164295; http://dx.doi.org/10.1074/jbc.M806702200.
-
(2009)
J Biol Chem
, vol.284
, pp. 8557-8566
-
-
Her, Y.R.1
Chung, I.K.2
-
45
-
-
84870730784
-
Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation
-
PMID:21643006
-
Zhang B, Qian D, Ma HH, Jin R, Yang PX, Cai MY, et al. Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation. Oncogene 2011; PMID:21643006.
-
(2011)
Oncogene
-
-
Zhang, B.1
Qian, D.2
Ma, H.H.3
Jin, R.4
Yang, P.X.5
Cai, M.Y.6
-
46
-
-
68349133311
-
Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance
-
PMID:19683498
-
Atanassov BS, Evrard YA, Multani AS, Zhang Z, Tora L, Devys D, et al. Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol Cell 2009; 35:352-64; PMID:19683498; http://dx.doi.org/10.1016/j.molcel.2009.06. 015.
-
(2009)
Mol Cell
, vol.35
, pp. 352-364
-
-
Atanassov, B.S.1
Evrard, Y.A.2
Multani, A.S.3
Zhang, Z.4
Tora, L.5
Devys, D.6
-
47
-
-
0345826106
-
Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription
-
PMID:14660634
-
Daniel JA, Torok MS, Sun ZW, Schieltz D, Allis CD, Yates JR, 3rd, et al. Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription. J Biol Chem 2004; 279:1867-71; PMID:14660634; http://dx.doi.org/10.1074/jbc.C300494200.
-
(2004)
J Biol Chem
, vol.279
, pp. 1867-1871
-
-
Daniel, J.A.1
Torok, M.S.2
Sun, Z.W.3
Schieltz, D.4
Allis, C.D.5
Yates III, J.R.6
-
48
-
-
2642535870
-
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
-
PMID:15133513
-
Ye JZ, de Lange T. TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex. Nat Genet 2004; 36:618-23; PMID:15133513; http://dx.doi.org/10.1038/ng1360.
-
(2004)
Nat Genet
, vol.36
, pp. 618-623
-
-
Ye, J.Z.1
De Lange, T.2
-
49
-
-
36549030804
-
Protein requirements for sister telomere association in human cells
-
PMID:17962804
-
Canudas S, Houghtaling BR, Kim JY, Dynek JN, Chang WG, Smith S. Protein requirements for sister telomere association in human cells. EMBO J 2007; 26:4867-78; PMID:17962804; http://dx.doi.org/10.1038/sj.emboj.7601903.
-
(2007)
EMBO J
, vol.26
, pp. 4867-4878
-
-
Canudas, S.1
Houghtaling, B.R.2
Kim, J.Y.3
Dynek, J.N.4
Chang, W.G.5
Smith, S.6
-
50
-
-
84863011409
-
TIN2 stability is regulated by the E3 ligase Siah2
-
PMID:22064479
-
Bhanot M, Smith S. TIN2 stability is regulated by the E3 ligase Siah2. Mol Cell Biol 2012; 32:376-84; PMID:22064479; http://dx.doi.org/10.1128/MCB. 06227-11.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 376-384
-
-
Bhanot, M.1
Smith, S.2
-
51
-
-
64549109258
-
A role for monoubiquitinated FANCD2 at telomeres in ALT cells
-
PMID:19129235
-
Fan Q, Zhang F, Barrett B, Ren K, Andreassen PR. A role for monoubiquitinated FANCD2 at telomeres in ALT cells. Nucleic Acids Res 2009; 37:1740-54; PMID:19129235; http://dx.doi.org/10.1093/nar/gkn995.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1740-1754
-
-
Fan, Q.1
Zhang, F.2
Barrett, B.3
Ren, K.4
Andreassen, P.R.5
-
52
-
-
77956536492
-
CST meets shelterin to keep telomeres in check
-
PMID:20832719
-
Giraud-Panis MJ, Teixeira MT, Géli V, Gilson E. CST meets shelterin to keep telomeres in check. Mol Cell 2010; 39:665-76; PMID:20832719; http://dx.doi.org/10.1016/j.molcel.2010.08.024.
-
(2010)
Mol Cell
, vol.39
, pp. 665-676
-
-
Giraud-Panis, M.J.1
Teixeira, M.T.2
Géli, V.3
Gilson, E.4
-
53
-
-
58149094903
-
Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell cycle progression
-
PMID:19135888
-
Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, Blackburn EH. Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell cycle progression. Cell 2009; 136:50-61; PMID:19135888; http://dx.doi.org/10.1016/j.cell.2008.11.027.
-
(2009)
Cell
, vol.136
, pp. 50-61
-
-
Li, S.1
Makovets, S.2
Matsuguchi, T.3
Blethrow, J.D.4
Shokat, K.M.5
Blackburn, E.H.6
-
54
-
-
79961029209
-
SUMOylation regulates telomere length homeostasis by targeting Cdc13
-
PMID:21743457
-
Hang LE, Liu X, Cheung I, Yang Y, Zhao X. SUMOylation regulates telomere length homeostasis by targeting Cdc13. Nat Struct Mol Biol 2011; 18:920-6; PMID:21743457; http://dx.doi.org/10.1038/nsmb.2100.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 920-926
-
-
Hang, L.E.1
Liu, X.2
Cheung, I.3
Yang, Y.4
Zhao, X.5
-
55
-
-
79960004074
-
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast
-
PMID:21666682
-
Ferreira HC, Luke B, Schober H, Kalck V, Lingner J, Gasser SM. The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nat Cell Biol 2011; 13:867-74; PMID:21666682; http://dx.doi.org/10.1038/ncb2263.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 867-874
-
-
Ferreira, H.C.1
Luke, B.2
Schober, H.3
Kalck, V.4
Lingner, J.5
Gasser, S.M.6
-
56
-
-
33846467848
-
Role of SUMO in the dynamics of telomere maintenance in fission yeast
-
PMID:17209013
-
Xhemalce B, Riising EM, Baumann P, Dejean A, Arcangioli B, Seeler JS. Role of SUMO in the dynamics of telomere maintenance in fission yeast. Proc Natl Acad Sci USA 2007; 104:893-8; PMID:17209013; http://dx.doi.org/10.1073/pnas. 0605442104.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 893-898
-
-
Xhemalce, B.1
Riising, E.M.2
Baumann, P.3
Dejean, A.4
Arcangioli, B.5
Seeler, J.S.6
-
57
-
-
77951230659
-
Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution
-
PMID:20159973
-
Chavez A, George V, Agrawal V, Johnson FB. Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution. J Biol Chem 2010; 285:11922-30; PMID:20159973; http://dx.doi.org/10.1074/jbc.M109.041277.
-
(2010)
J Biol Chem
, vol.285
, pp. 11922-11930
-
-
Chavez, A.1
George, V.2
Agrawal, V.3
Johnson, F.B.4
-
58
-
-
34447129654
-
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
-
PMID:17589526
-
Potts PR, Yu H. The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat Struct Mol Biol 2007; 14:581-90; PMID:17589526; http://dx.doi.org/10.1038/nsmb1259.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 581-590
-
-
Potts, P.R.1
Yu, H.2
-
59
-
-
61649085240
-
Sumoylation of RecQ helicase controls the fate of dysfunctional telomeres
-
PMID:19285940
-
Rog O, Miller KM, Ferreira MG, Cooper JP. Sumoylation of RecQ helicase controls the fate of dysfunctional telomeres. Mol Cell 2009; 33:559-69; PMID:19285940; http://dx.doi.org/10.1016/j.molcel.2009.01.027.
-
(2009)
Mol Cell
, vol.33
, pp. 559-569
-
-
Rog, O.1
Miller, K.M.2
Ferreira, M.G.3
Cooper, J.P.4
-
60
-
-
77449147101
-
Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast
-
PMID:19906698
-
Lu CY, Tsai CH, Brill SJ, Teng SC. Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast. Nucleic Acids Res 2010; 38:488-98; PMID:19906698; http://dx.doi.org/10.1093/nar/gkp1008.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 488-498
-
-
Lu, C.Y.1
Tsai, C.H.2
Brill, S.J.3
Teng, S.C.4
-
61
-
-
84864499620
-
RecQ helicases in DNA double strand break repair and telomere maintenance
-
PMID:21689668
-
Singh DK, Ghosh AK, Croteau DL, Bohr VA. RecQ helicases in DNA double strand break repair and telomere maintenance. Mutat Res 2011; PMID:21689668; http://dx.doi.org/10.1016/j.mrfmmm.2011.06.002.
-
(2011)
Mutat Res
-
-
Singh, D.K.1
Ghosh, A.K.2
Croteau, D.L.3
Bohr, V.A.4
-
62
-
-
84855266777
-
RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance
-
PMID:22039056
-
Ghosh AK, Rossi ML, Singh DK, Dunn C, Ramamoorthy M, Croteau DL, et al. RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance. J Biol Chem 2012; 287:196-209; PMID:22039056; http://dx.doi.org/10. 1074/jbc.M111.295063.
-
(2012)
J Biol Chem
, vol.287
, pp. 196-209
-
-
Ghosh, A.K.1
Rossi, M.L.2
Singh, D.K.3
Dunn, C.4
Ramamoorthy, M.5
Croteau, D.L.6
-
63
-
-
10344256183
-
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
-
PMID:15591207
-
Crabbe L, Verdun RE, Haggblom CI, Karlseder J. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 2004; 306:1951-3; PMID:15591207; http://dx.doi.org/10.1126/science.1103619.
-
(2004)
Science
, vol.306
, pp. 1951-1953
-
-
Crabbe, L.1
Verdun, R.E.2
Haggblom, C.I.3
Karlseder, J.4
-
64
-
-
68949149732
-
Multiple roles for MRE11 at uncapped telomeres
-
PMID:19633651
-
Deng Y, Guo X, Ferguson DO, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature 2009; 460:914-8; PMID:19633651; http://dx.doi.org/10.1038/ nature08196.
-
(2009)
Nature
, vol.460
, pp. 914-918
-
-
Deng, Y.1
Guo, X.2
Ferguson, D.O.3
Chang, S.4
-
65
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
PMID:21363960
-
Polo SE, Jackson SP. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev 2011; 25:409-33; PMID:21363960; http://dx.doi.org/10.1101/gad.2021311.
-
(2011)
Genes Dev
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
66
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
PMID:18001824
-
Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007; 131:887-900; PMID:18001824; http://dx.doi.org/10.1016/j.cell.2007.09.040.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
-
67
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
PMID:19203579
-
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009; 136:435-46; PMID:19203579; http://dx.doi.org/10.1016/j.cell.2008.12.041.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
-
68
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
PMID:18006705
-
Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, Sweeney FD, et al. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 2007; 318:1637-40; PMID:18006705; http://dx.doi.org/10.1126/science.1150034.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
-
69
-
-
84862986431
-
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
-
Bekker-Jensen S, Rendtlew Danielsen J, Fugger K, Gromova I, Nerstedt A, Lukas C, et al. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes. Nat Cell Biol 2010; 12:80-6.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 80-86
-
-
Bekker-Jensen, S.1
Rendtlew Danielsen, J.2
Fugger, K.3
Gromova, I.4
Nerstedt, A.5
Lukas, C.6
-
70
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
PMID:20725033
-
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, et al. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 2010; 466:941-6; PMID:20725033; http://dx.doi.org/10.1038/nature09297.
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
-
71
-
-
84859530323
-
Fusing telomeres with RNF8
-
In Press
-
Jacobs JJ. Fusing telomeres with RNF8. Nucleus 2012; 3: In Press.
-
(2012)
Nucleus
, vol.3
-
-
Jacobs, J.J.1
-
72
-
-
82955233817
-
The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection
-
PMID:22101936
-
Rai R, Li JM, Zheng H, Lok GT, Deng Y, Huen MS, et al. The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection. Nat Struct Mol Biol 2011; 18:1400-7; PMID:22101936; http://dx.doi.org/10.1038/nsmb.2172.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1400-1407
-
-
Rai, R.1
Li, J.M.2
Zheng, H.3
Lok, G.T.4
Deng, Y.5
Huen, M.S.6
-
73
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
PMID:17687332
-
Denchi EL, de Lange T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 2007; 448:1068-71; PMID:17687332; http://dx.doi.org/10.1038/nature06065.
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
De Lange, T.2
-
74
-
-
78649819167
-
Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence
-
PMID:21057505
-
Fujita K, Horikawa I, Mondal AM, Jenkins LM, Appella E, Vojtesek B, et al. Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Nat Cell Biol 2010; 12:1205-12; PMID:21057505; http://dx.doi.org/10.1038/ncb2123.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1205-1212
-
-
Fujita, K.1
Horikawa, I.2
Mondal, A.M.3
Jenkins, L.M.4
Appella, E.5
Vojtesek, B.6
-
75
-
-
0036843088
-
A role for the Rb family of proteins in controlling telomere length
-
PMID:12379853
-
García-Cao M, Gonzalo S, Dean D, Blasco MA. A role for the Rb family of proteins in controlling telomere length. Nat Genet 2002; 32:415-9; PMID:12379853; http://dx.doi.org/10.1038/ng1011.
-
(2002)
Nat Genet
, vol.32
, pp. 415-419
-
-
García-Cao, M.1
Gonzalo, S.2
Dean, D.3
Blasco, M.A.4
-
76
-
-
0347988045
-
Epigenetic regulation of telomere length in mammalian cells by the Suv39 h1 and Suv39 h2 histone methyltransferases
-
PMID:14702045
-
García-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA. Epigenetic regulation of telomere length in mammalian cells by the Suv39 h1 and Suv39 h2 histone methyltransferases. Nat Genet 2004; 36:94-9; PMID:14702045; http://dx.doi.org/10.1038/ng1278.
-
(2004)
Nat Genet
, vol.36
, pp. 94-99
-
-
García-Cao, M.1
O'Sullivan, R.2
Peters, A.H.3
Jenuwein, T.4
Blasco, M.A.5
-
77
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
PMID:15750587
-
Gonzalo S, García-Cao M, Fraga MF, Schotta G, Peters AH, Cotter SE, et al. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 2005; 7:420-8; PMID:15750587; http://dx.doi.org/10.1038/ncb1235.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
García-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.5
Cotter, S.E.6
-
78
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
PMID:16565708
-
Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, et al. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 2006; 8:416-24; PMID:16565708; http://dx.doi.org/10.1038/ncb1386.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
-
79
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
PMID:17237781
-
Benetti R, García-Cao M, Blasco MA. Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 2007; 39:243-50; PMID:17237781; http://dx.doi.org/10.1038/ng1952.
-
(2007)
Nat Genet
, vol.39
, pp. 243-250
-
-
Benetti, R.1
García-Cao, M.2
Blasco, M.A.3
-
80
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
PMID:20890289
-
O'Sullivan RJ, Kubicek S, Schreiber SL, Karlseder J. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat Struct Mol Biol 2010; 17:1218-25; PMID:20890289; http://dx.doi.org/10.1038/ nsmb.1897.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
Kubicek, S.2
Schreiber, S.L.3
Karlseder, J.4
-
81
-
-
80054002567
-
Suv4-20 h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells
-
PMID:22022429
-
Marión RM, Schotta G, Ortega S, Blasco MA. Suv4-20 h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells. PLoS One 2011; 6:25680; PMID:22022429; http://dx.doi.org/10.1371/journal.pone.0025680.
-
(2011)
PLoS One
, vol.6
, pp. 25680
-
-
Marión, R.M.1
Schotta, G.2
Ortega, S.3
Blasco, M.A.4
-
82
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NFkappaB-dependent gene expression and organismal lifespan
-
PMID:19135889
-
Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, et al. SIRT6 links histone H3 lysine 9 deacetylation to NFkappaB-dependent gene expression and organismal lifespan. Cell 2009; 136:62-74; PMID:19135889; http://dx.doi.org/10.1016/j.cell.2008.10.052.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
-
83
-
-
33751113602
-
Mammalian sirtuins - Emerging roles in physiology, aging and calorie restriction
-
PMID:17079682
-
Haigis MC, Guarente LP. Mammalian sirtuins - emerging roles in physiology, aging and calorie restriction. Genes Dev 2006; 20:2913-21; PMID:17079682; http://dx.doi.org/10.1101/gad.1467506.
-
(2006)
Genes Dev
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
84
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
PMID:18337721
-
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 2008; 452:492-6; PMID:18337721; http://dx.doi.org/10.1038/ nature06736.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
-
85
-
-
69249221533
-
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
-
PMID:19625767
-
Michishita E, McCord RA, Boxer LD, Barber MF, Hong T, Gozani O, et al. Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle 2009; 8:2664-6; PMID:19625767; http://dx.doi.org/10.4161/cc.8. 16.9367.
-
(2009)
Cell Cycle
, vol.8
, pp. 2664-2666
-
-
Michishita, E.1
McCord, R.A.2
Boxer, L.D.3
Barber, M.F.4
Hong, T.5
Gozani, O.6
-
86
-
-
78650747994
-
SIRT1 contributes to telomere maintenance and augments global homologous recombination
-
PMID:21187328
-
Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M, Blasco MA. SIRT1 contributes to telomere maintenance and augments global homologous recombination. J Cell Biol 2010; 191:1299-313; PMID:21187328; http://dx.doi.org/10.1083/jcb.201005160.
-
(2010)
J Cell Biol
, vol.191
, pp. 1299-1313
-
-
Palacios, J.A.1
Herranz, D.2
De Bonis, M.L.3
Velasco, S.4
Serrano, M.5
Blasco, M.A.6
-
87
-
-
80052399287
-
SIRT6 is required for maintenance of telomere position effect in human cells
-
PMID:21847107
-
Tennen RI, Bua DJ, Wright WE, Chua KF. SIRT6 is required for maintenance of telomere position effect in human cells. Nat Commun 2011; 2:433; PMID:21847107; http://dx.doi.org/10.1038/ncomms1443.
-
(2011)
Nat Commun
, vol.2
, pp. 433
-
-
Tennen, R.I.1
Bua, D.J.2
Wright, W.E.3
Chua, K.F.4
-
88
-
-
0032553473
-
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
-
PMID:9822378
-
Smith S, Giriat I, Schmitt A, de Lange T. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 1998; 282:1484-7; PMID:9822378; http://dx.doi.org/10.1126/science.282.5393.1484.
-
(1998)
Science
, vol.282
, pp. 1484-1487
-
-
Smith, S.1
Giriat, I.2
Schmitt, A.3
De Lange, T.4
-
89
-
-
0034687248
-
Tankyrase promotes telomere elongation in human cells
-
PMID:11069113
-
Smith S, de Lange T. Tankyrase promotes telomere elongation in human cells. Curr Biol 2000; 10:1299-302; PMID:11069113; http://dx.doi.org/10.1016/ S0960-9822(00)00752-1.
-
(2000)
Curr Biol
, vol.10
, pp. 1299-1302
-
-
Smith, S.1
De Lange, T.2
-
90
-
-
1842424729
-
Resolution of sister telomere association is required for progression through mitosis
-
PMID:15064417
-
Dynek JN, Smith S. Resolution of sister telomere association is required for progression through mitosis. Science 2004; 304:97-100; PMID:15064417; http://dx.doi.org/10.1126/science.1094754.
-
(2004)
Science
, vol.304
, pp. 97-100
-
-
Dynek, J.N.1
Smith, S.2
-
91
-
-
79953322962
-
Regulatory roles of tankyrase 1 at telomeres and in DNA repair: Suppression of T-SCE and stabilization of DNA-PKcs
-
(Albany NY) PMID:21037379
-
Dregalla RC, Zhou J, Idate RR, Battaglia CL, Liber HL, Bailey SM. Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs. Aging (Albany NY) 2010; 2:691-708; PMID:21037379.
-
(2010)
Aging
, vol.2
, pp. 691-708
-
-
Dregalla, R.C.1
Zhou, J.2
Idate, R.R.3
Battaglia, C.L.4
Liber, H.L.5
Bailey, S.M.6
-
92
-
-
84855714282
-
Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation
-
PMID:21818122
-
Ha GH, Kim HS, Go H, Lee H, Seimiya H, Chung DH, et al. Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation. Cell Death Differ 2012; 19:321-32; PMID:21818122; http://dx.doi.org/10.1038/cdd.2011.101.
-
(2012)
Cell Death Differ
, vol.19
, pp. 321-332
-
-
Ha, G.H.1
Kim, H.S.2
Go, H.3
Lee, H.4
Seimiya, H.5
Chung, D.H.6
-
93
-
-
54449087207
-
Plk1 phosphorylation of TRF1 is essential for its binding to telomeres
-
PMID:18625707
-
Wu ZQ, Yang X, Weber G, Liu X. Plk1 phosphorylation of TRF1 is essential for its binding to telomeres. J Biol Chem 2008; 283:25503-13; PMID:18625707; http://dx.doi.org/10.1074/jbc.M803304200.
-
(2008)
J Biol Chem
, vol.283
, pp. 25503-25513
-
-
Wu, Z.Q.1
Yang, X.2
Weber, G.3
Liu, X.4
-
94
-
-
80052326060
-
Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
-
PMID:21314979
-
Lyakhovich A, Ramirez MJ, Castellanos A, Castella M, Simons AM, Parvin JD, et al. Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner. Genome Integr 2011; 2:4; PMID:21314979; http://dx.doi.org/10.1186/2041-9414-2-4.
-
(2011)
Genome Integr
, vol.2
, pp. 4
-
-
Lyakhovich, A.1
Ramirez, M.J.2
Castellanos, A.3
Castella, M.4
Simons, A.M.5
Parvin, J.D.6
-
95
-
-
27444434379
-
DNA damage-induced phosphorylation of the human telomere-associated protein TRF2
-
PMID:16223874
-
Tanaka H, Mendonca MS, Bradshaw PS, Hoelz DJ, Malkas LH, Meyn MS, et al. DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. Proc Natl Acad Sci USA 2005; 102:15539-44; PMID:16223874; http://dx.doi.org/10.1073/pnas.0507915102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15539-15544
-
-
Tanaka, H.1
Mendonca, M.S.2
Bradshaw, P.S.3
Hoelz, D.J.4
Malkas, L.H.5
Meyn, M.S.6
-
96
-
-
35848939383
-
The protein kinase Aurora C phosphorylates TRF2
-
PMID:18309533
-
Spengler D. The protein kinase Aurora C phosphorylates TRF2. Cell Cycle 2007; 6:2579-80; PMID:18309533; http://dx.doi.org/10.4161/cc.6.20.4781.
-
(2007)
Cell Cycle
, vol.6
, pp. 2579-2580
-
-
Spengler, D.1
-
97
-
-
67349246601
-
The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage
-
PMID:19375317
-
Buscemi G, Zannini L, Fontanella E, Lecis D, Lisanti S, Delia D. The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage. Curr Biol 2009; 19:874-9; PMID:19375317; http://dx.doi.org/10.1016/j. cub.2009.03.064.
-
(2009)
Curr Biol
, vol.19
, pp. 874-879
-
-
Buscemi, G.1
Zannini, L.2
Fontanella, E.3
Lecis, D.4
Lisanti, S.5
Delia, D.6
-
98
-
-
32544447429
-
Cell cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase
-
PMID:16424898
-
Nishiyama A, Muraki K, Saito M, Ohsumi K, Kishimoto T, Ishikawa F. Cell cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase. EMBO J 2006; 25:575-84; PMID:16424898; http://dx.doi.org/10. 1038/sj.emboj.7600964.
-
(2006)
EMBO J
, vol.25
, pp. 575-584
-
-
Nishiyama, A.1
Muraki, K.2
Saito, M.3
Ohsumi, K.4
Kishimoto, T.5
Ishikawa, F.6
-
99
-
-
34548492016
-
MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
-
PMID:17694070
-
Wu Y, Xiao S, Zhu XD. MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control. Nat Struct Mol Biol 2007; 14:832-40; PMID:17694070; http://dx.doi.org/10.1038/nsmb1286.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 832-840
-
-
Wu, Y.1
Xiao, S.2
Zhu, X.D.3
-
100
-
-
46649111985
-
Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation
-
PMID:18347021
-
Kim MK, Kang MR, Nam HW, Bae YS, Kim YS, Chung IK. Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation. J Biol Chem 2008; 283:14144-52; PMID:18347021; http://dx.doi.org/10.1074/jbc.M710065200.
-
(2008)
J Biol Chem
, vol.283
, pp. 14144-14152
-
-
Kim, M.K.1
Kang, M.R.2
Nam, H.W.3
Bae, Y.S.4
Kim, Y.S.5
Chung, I.K.6
-
101
-
-
84860345945
-
ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance
-
PMID:22266654
-
McKerlie MA, Lin S, Zhu XD. ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance. Nucleic Acids Res 2012; PMID:22266654; http://dx.doi.org/10.1093/nar/gks035.
-
(2012)
Nucleic Acids Res
-
-
McKerlie, M.A.1
Lin, S.2
Zhu, X.D.3
-
102
-
-
84880307126
-
Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres
-
PMID:21712819
-
McKerlie M, Zhu XD. Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres. Nat Commun 2011; 2:371; PMID:21712819; http://dx.doi.org/10.1038/ncomms1372.
-
(2011)
Nat Commun
, vol.2
, pp. 371
-
-
McKerlie, M.1
Zhu, X.D.2
-
103
-
-
60549089999
-
Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening
-
PMID:19160102
-
Chen YC, Teng SC, Wu KJ. Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening. Cancer Invest 2009; 27:24-8; PMID:19160102; http://dx.doi.org/10.1080/07357900802027081.
-
(2009)
Cancer Invest
, vol.27
, pp. 24-28
-
-
Chen, Y.C.1
Teng, S.C.2
Wu, K.J.3
-
104
-
-
77952318450
-
Rnf8 deficiency impairs class switch recombination, spermatogenesis and genomic integrity and predisposes for cancer
-
PMID:20385750
-
Li L, Halaby MJ, Hakem A, Cardoso R, El Ghamrasni S, Harding S, et al. Rnf8 deficiency impairs class switch recombination, spermatogenesis and genomic integrity and predisposes for cancer. J Exp Med 2010; 207:983-97; PMID:20385750; http://dx.doi.org/10.1084/jem.20092437.
-
(2010)
J Exp Med
, vol.207
, pp. 983-997
-
-
Li, L.1
Halaby, M.J.2
Hakem, A.3
Cardoso, R.4
El Ghamrasni, S.5
Harding, S.6
-
105
-
-
80052717417
-
Ubiquitylation and the Fanconi anemia pathway
-
PMID:21605559
-
Garner E, Smogorzewska A. Ubiquitylation and the Fanconi anemia pathway. FEBS Lett 2011; 585:2853-60; PMID:21605559; http://dx.doi.org/10.1016/j.febslet. 2011.04.078.
-
(2011)
FEBS Lett
, vol.585
, pp. 2853-2860
-
-
Garner, E.1
Smogorzewska, A.2
-
106
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
PMID:19203578
-
Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, et al. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009; 136:420-34; PMID:19203578; http://dx.doi.org/10.1016/j.cell.2008.12.042.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
-
107
-
-
79955627875
-
Genomic instability, defective spermatogenesis, immunodeficiency and cancer in a mouse model of the RIDDLE syndrome
-
PMID:21552324
-
Bohgaki T, Bohgaki M, Cardoso R, Panier S, Zeegers D, Li L, et al. Genomic instability, defective spermatogenesis, immunodeficiency and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet 2011; 7:1001381; PMID:21552324; http://dx.doi.org/10.1371/journal.pgen.1001381.
-
(2011)
PLoS Genet
, vol.7
, pp. 1001381
-
-
Bohgaki, T.1
Bohgaki, M.2
Cardoso, R.3
Panier, S.4
Zeegers, D.5
Li, L.6
|