메뉴 건너뛰기




Volumn 119, Issue 16, 2012, Pages 3779-3789

Efficacy of vorinostat in a murine model of polycythemia vera

Author keywords

[No Author keywords available]

Indexed keywords

FOG1 PROTEIN; JANUS KINASE 2; KRUPPEL LIKE FACTOR 1 POTEIN; PLACEBO; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG; VORINOSTAT;

EID: 84860316991     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-02-336743     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937-951.
    • (2009) Blood , vol.114 , Issue.5 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 2
    • 55249095625 scopus 로고    scopus 로고
    • Myeloproliferative disorders
    • Levine RL, Gilliland DG. Myeloproliferative disorders. Blood. 2008;112(6):2190-2198.
    • (2008) Blood , vol.112 , Issue.6 , pp. 2190-2198
    • Levine, R.L.1    Gilliland, D.G.2
  • 7
    • 77951759127 scopus 로고    scopus 로고
    • Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease
    • Akada H, Yan D, Zou H, Fiering S, Hutchison RE, Mohi MG. Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera-like disease. Blood. 2010;115(17):3589-3597.
    • (2010) Blood , vol.115 , Issue.17 , pp. 3589-3597
    • Akada, H.1    Yan, D.2    Zou, H.3    Fiering, S.4    Hutchison, R.E.5    Mohi, M.G.6
  • 8
    • 79953247371 scopus 로고    scopus 로고
    • Differential biological activity of disease-associated JAK2 mutants
    • Zou H, Yan D, Mohi G. Differential biological activity of disease-associated JAK2 mutants. FEBS Lett. 2011;585(7):1007-1013.
    • (2011) FEBS Lett. , vol.585 , Issue.7 , pp. 1007-1013
    • Zou, H.1    Yan, D.2    Mohi, G.3
  • 9
    • 77949535491 scopus 로고    scopus 로고
    • Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis
    • Santos FP, Kantarjian HM, Jain N, et al. Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Blood. 2010;115(6):1131-1136.
    • (2010) Blood , vol.115 , Issue.6 , pp. 1131-1136
    • Santos, F.P.1    Kantarjian, H.M.2    Jain, N.3
  • 10
    • 79952333359 scopus 로고    scopus 로고
    • Safety and Efficacy of TG101348, a Selective JAK2 Inhibitor, in Myelofibrosis
    • Pardanani A, Gotlib JR, Jamieson C, et al. Safety and Efficacy of TG101348, a Selective JAK2 Inhibitor, in Myelofibrosis. J Clin Oncol. 2011;29(7): 789-796.
    • (2011) J Clin Oncol. , vol.29 , Issue.7 , pp. 789-796
    • Pardanani, A.1    Gotlib, J.R.2    Jamieson, C.3
  • 12
    • 18244432009 scopus 로고    scopus 로고
    • Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
    • DOI 10.1016/S0092-8674(00)81168-X
    • Neubauer H, Cumano A, Müller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 1998;93(3):397-409. (Pubitemid 28232084)
    • (1998) Cell , vol.93 , Issue.3 , pp. 397-409
    • Neubauer, H.1    Cumano, A.2    Muller, M.3    Wu, H.4    Huffstadt, U.5    Pfeffer, K.6
  • 13
    • 80054028202 scopus 로고    scopus 로고
    • Long-term outcome of treatment with ruxolitinib in myelofibrosis
    • Tefferi A, Litzow MR, Pardanani A. Long-term outcome of treatment with ruxolitinib in myelofibrosis. N Engl J Med. 2011;365(15):1455-1457.
    • (2011) N Engl J Med. , vol.365 , Issue.15 , pp. 1455-1457
    • Tefferi, A.1    Litzow, M.R.2    Pardanani, A.3
  • 14
    • 78651337547 scopus 로고    scopus 로고
    • Seeking the causes and solutions to imatinib-resistance in chronic myeloid leukemia
    • Bixby D, Talpaz M. Seeking the causes and solutions to imatinib-resistance in chronic myeloid leukemia. Leukemia. 2011;25(1):7-22.
    • (2011) Leukemia , vol.25 , Issue.1 , pp. 7-22
    • Bixby, D.1    Talpaz, M.2
  • 15
    • 21244467166 scopus 로고    scopus 로고
    • Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies
    • DOI 10.1200/JCO.2005.16.600
    • Bhalla KN. Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies. J Clin Oncol. 2005;23(17):3971-3993. (Pubitemid 46218700)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.17 , pp. 3971-3993
    • Bhalla, K.N.1
  • 16
    • 2542448184 scopus 로고    scopus 로고
    • Modification of hematopoietic stem cell fate by 5aza 2′ deoxycytidine and trichostatin A
    • DOI 10.1182/blood-2003-07-2431
    • Milhem M, Mahmud N, Lavelle D, et al. Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A. Blood. 2004; 103(11):4102-4110. (Pubitemid 38685350)
    • (2004) Blood , vol.103 , Issue.11 , pp. 4102-4110
    • Milhem, M.1    Mahmud, N.2    Lavelle, D.3    Araki, H.4    DeSimone, J.5    Saunthararajah, Y.6    Hoffman, R.7
  • 19
    • 31844449339 scopus 로고    scopus 로고
    • Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents
    • DOI 10.1016/j.exphem.2005.10.002, PII S0301472X05005011
    • Araki H, Mahmud N, Milhem M, et al. Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents. Exp Hematol. 2006;34(2006):140-149. (Pubitemid 43184319)
    • (2006) Experimental Hematology , vol.34 , Issue.2 , pp. 140-149
    • Araki, H.1    Mahmud, N.2    Milhem, M.3    Nunez, R.4    Xu, M.5    Beam, C.A.6    Hoffman, R.7
  • 20
    • 34147175640 scopus 로고    scopus 로고
    • Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential
    • DOI 10.1182/blood-2006-07-035287
    • Araki H, Yoshinaga K, Boccuni P, Zhao Y, Hoffman R, Mahmud N. Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. Blood. 2007;109(8): 3570-3578. (Pubitemid 46572552)
    • (2007) Blood , vol.109 , Issue.8 , pp. 3570-3578
    • Araki, H.1    Yoshinaga, K.2    Boccuni, P.3    Zhao, Y.4    Hoffman, R.5    Mahmud, N.6
  • 21
    • 33847258674 scopus 로고    scopus 로고
    • Discovery and development of SAHA as an anticancer agent
    • DOI 10.1038/sj.onc.1210204, PII 1210204
    • Marks PA. Discovery and development of SAHA as an anticancer agent. Oncogene. 2007;26(9): 1351-1356. (Pubitemid 46328465)
    • (2007) Oncogene , vol.26 , Issue.9 , pp. 1351-1356
    • Marks, P.A.1
  • 24
    • 73949136283 scopus 로고    scopus 로고
    • Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells
    • Wang Y, Fiskus W, Chong DG, et al. Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells. Blood. 2009; 114(24):5024-5033.
    • (2009) Blood , vol.114 , Issue.24 , pp. 5024-5033
    • Wang, Y.1    Fiskus, W.2    Chong, D.G.3
  • 27
    • 36148950997 scopus 로고    scopus 로고
    • FDA approval summary: Vorinostat for treatment of advanced primary cutaneous T-cell lymphoma
    • DOI 10.1634/theoncologist.12-10-1247
    • Mann BS, Johnson JR, Cohen MH, Justice R, Pazdur R. FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma. Oncologist. 2007;12(10):1247-1252. (Pubitemid 350106355)
    • (2007) Oncologist , vol.12 , Issue.10 , pp. 1247-1252
    • Mann, B.S.1    Johnson, J.R.2    Cohen, M.H.3    Justice, R.4    Pazdur, R.5
  • 30
    • 57449114002 scopus 로고    scopus 로고
    • Enhanced histone deacetylase enzyme activity in primary myelofibrosis
    • Wang JC, Chen C, Dumlao T, et al. Enhanced histone deacetylase enzyme activity in primary myelofibrosis. Leuk Lymphoma. 2008;49(12): 2321-2327.
    • (2008) Leuk Lymphoma , vol.49 , Issue.12 , pp. 2321-2327
    • Wang, J.C.1    Chen, C.2    Dumlao, T.3
  • 31
    • 78650670563 scopus 로고    scopus 로고
    • Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells
    • Wang X, Zhang W, Tripodi J, et al. Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells. Blood. 2010;116(26): 5972-5982.
    • (2010) Blood , vol.116 , Issue.26 , pp. 5972-5982
    • Wang, X.1    Zhang, W.2    Tripodi, J.3
  • 32
    • 67349127967 scopus 로고    scopus 로고
    • Clinical efficacy of vorinostat in a patient with essential thrombocytosis and subsequent myelofibrosis
    • Lee J. Clinical efficacy of vorinostat in a patient with essential thrombocytosis and subsequent myelofibrosis. Ann Hematol. 2009;88(7):699-700.
    • (2009) Ann Hematol. , vol.88 , Issue.7 , pp. 699-700
    • Lee, J.1
  • 34
    • 47149112573 scopus 로고    scopus 로고
    • Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2
    • Grebien F, Kerenyi MA, Kovacic B, et al. Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood. 2008;111(9):4511-4522.
    • (2008) Blood , vol.111 , Issue.9 , pp. 4511-4522
    • Grebien, F.1    Kerenyi, M.A.2    Kovacic, B.3
  • 35
    • 47049098437 scopus 로고    scopus 로고
    • Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders
    • Hexner EO, Serdikoff C, Jan M, et al. Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders. Blood. 2008;111(12): 5663-5671.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5663-5671
    • Hexner, E.O.1    Serdikoff, C.2    Jan, M.3
  • 36
    • 33646546386 scopus 로고    scopus 로고
    • The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
    • Jamieson CH, Gotlib J, Durocher JA, et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A. 2006;103(16):6224-6229.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.16 , pp. 6224-6229
    • Jamieson, C.H.1    Gotlib, J.2    Durocher, J.A.3
  • 37
    • 0016391236 scopus 로고
    • Bone-marrow responses in polycythemia vera
    • Prchal JF, Axelrad AA. Bone-marrow responses in polycythemia vera. N Engl J Med. 1974; 290(24):1382.
    • (1974) N Engl J Med. , vol.290 , Issue.24 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 38
    • 0037108448 scopus 로고    scopus 로고
    • BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90
    • Gorre ME, Ellwood-Yen K, Chiosis G, Rosen N, Sawyers CL. BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90. Blood. 2002;100(8):3041-3044.
    • (2002) Blood , vol.100 , Issue.8 , pp. 3041-3044
    • Gorre, M.E.1    Ellwood-Yen, K.2    Chiosis, G.3    Rosen, N.4    Sawyers, C.L.5
  • 39
    • 20844444898 scopus 로고    scopus 로고
    • Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3
    • DOI 10.1182/blood-2004-09-3413
    • George P, Bali P, Annavarapu S, et al. Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3. Blood. 2005;105(4): 1768-1776. (Pubitemid 40223701)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1768-1776
    • George, P.1    Bali, P.2    Annavarapu, S.3    Scuto, A.4    Fiskus, W.5    Guo, F.6    Sigua, C.7    Sondarva, G.8    Moscinski, L.9    Atadja, P.10    Bhalla, K.11
  • 40
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • DOI 10.1038/nri2093, PII NRI2093
    • Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol. 2007;7(6):454-465. (Pubitemid 46834848)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 41
    • 35348903151 scopus 로고    scopus 로고
    • Transcriptional control of erythropoiesis: Emerging mechanisms and principles
    • DOI 10.1038/sj.onc.1210761, PII 1210761
    • Kim SI, Bresnick E. Transcriptional control of erythropoiesis: emerging mechanisms and principles. Oncogene. 2007;26(47):6777-6794. (Pubitemid 47585102)
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6777-6794
    • Kim, S.-I.1    Bresnick, E.H.2
  • 42
    • 78649410968 scopus 로고    scopus 로고
    • Networking erythropoiesis
    • Kerenyi MA, Orkin SH. Networking erythropoiesis. J Exp Med. 2010;207(12):2537-2541.
    • (2010) J Exp Med. , vol.207 , Issue.12 , pp. 2537-2541
    • Kerenyi, M.A.1    Orkin, S.H.2
  • 43
    • 35348875999 scopus 로고    scopus 로고
    • Transcriptional control of granulocyte and monocyte development
    • DOI 10.1038/sj.onc.1210764, PII 1210764
    • Friedman AD. Transcriptional control of granulocyte and monocyte development. Oncogene. 2007;26(47):6816-6828. (Pubitemid 47585105)
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6816-6828
    • Friedman, A.D.1
  • 44
    • 77949886046 scopus 로고    scopus 로고
    • Nonclinical safety assessment of the histone deacetylase inhibitor vorinostat
    • Kerr JS, Galloway S, Lagrutta A, et al. Nonclinical safety assessment of the histone deacetylase inhibitor vorinostat. Int J Toxicol. 2010;29(1):3-19.
    • (2010) Int J Toxicol. , vol.29 , Issue.1 , pp. 3-19
    • Kerr, J.S.1    Galloway, S.2    Lagrutta, A.3
  • 45
    • 77957854088 scopus 로고    scopus 로고
    • HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans
    • Marubayashi S, Koppikar P, Taldone T, et al. HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans. J Clin Invest. 2010;120(10):3578-3593.
    • (2010) J Clin Invest. , vol.120 , Issue.10 , pp. 3578-3593
    • Marubayashi, S.1    Koppikar, P.2    Taldone, T.3
  • 46
    • 43549109620 scopus 로고    scopus 로고
    • The Jak2V617F oncogene associated with myelopro-liferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes
    • Wernig G, Gonneville JR, Crowley BJ, et al. The Jak2V617F oncogene associated with myelopro-liferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes. Blood. 2008; 111(7):3751-3759.
    • (2008) Blood , vol.111 , Issue.7 , pp. 3751-3759
    • Wernig, G.1    Gonneville, J.R.2    Crowley, B.J.3
  • 47
    • 84855242836 scopus 로고    scopus 로고
    • Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells
    • Xiong H, Du W, Zhang YJ, et al. Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells. Mol Carcinog. 2012;51(2):174-184.
    • (2012) Mol Carcinog. , vol.51 , Issue.2 , pp. 174-184
    • Xiong, H.1    Du, W.2    Zhang, Y.J.3
  • 49
    • 79960608530 scopus 로고    scopus 로고
    • JAK2 V617F-dependent upregulation of PU. 1 expression in the peripheral blood of myeloproliferative neoplasm patients
    • Irino T, Uemura M, Yamane H, et al. JAK2 V617F-dependent upregulation of PU. 1 expression in the peripheral blood of myeloproliferative neoplasm patients. PLoS One. 2011;6(7):e22148.
    • (2011) PLoS One , vol.6 , Issue.7
    • Irino, T.1    Uemura, M.2    Yamane, H.3
  • 50
    • 84856911269 scopus 로고    scopus 로고
    • A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
    • Kaufmann KB, Grunder A, Hadlich T, et al. A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2. J Exp Med. 2012;209(1): 35-50.
    • (2012) J Exp Med. , vol.209 , Issue.1 , pp. 35-50
    • Kaufmann, K.B.1    Grunder, A.2    Hadlich, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.