The enduring enigma of nuclear translation

Journal of Cell Biology

Volumn 197, Issue 1, 2012, Pages 7-9

  Reid, David W ^a   Nicchitta, Christopher V ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RNA POLYMERASE II; TRANSFER RNA;

CELL NUCLEUS; CODON; CYTOLOGY; CYTOPLASM; GENE CONTROL; NONSENSE MUTATION; NOTE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA TRANSLATION; TRANSLATION INITIATION;

CELL NUCLEUS; HUMANS; PROTEIN BIOSYNTHESIS; PUROMYCIN; RIBOSOMES;

EID: 84860304296     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201202140     Document Type: Note

References (22)

1. Allfrey, V.G. 1954. Amino acid incorporation by isolated thymus nuclei. I. The role of desoxyribonucleic acid in protein synthesis. Proc. Natl. Acad. Sci. USA. 40:881-885. http://dx.doi.org/10.1073/pnas.40.10.881
2. Belgrader, P., J. Cheng, and L.E. Maquat. 1993. Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA. Proc. Natl. Acad. Sci. USA. 90:482-486. http://dx.doi.org/10.1073/pnas.90.2.482
3. Birnstiel, M.L., and W.G. Flamm. 1964. Intranuclear site of histone synthesis. Science. 145:1435-1437. http://dx.doi.org/10.1126/science.145.3639.1435
4. Bohnsack, M.T., K. Regener, B. Schwappach, R. Saffrich, E. Paraskeva, E. Hartmann, and D. Görlich. 2002. Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J. 21:6205-6215. http://dx.doi.org/10.1093/emboj/cdf613
5. Brogna, S., T.A. Sato, and M. Rosbash. 2002. Ribosome components are associated with sites of transcription. Mol. Cell. 10:93-104. http://dx.doi.org/10.1016/S1097-2765(02)00565-8
6. Corral-Debrinski, M., C. Blugeon, and C. Jacq. 2000. In yeast, the 3' untranslated region or the presequence of ATM1 is required for the exclusive localization of its mRNA to the vicinity of mitochondria. Mol. Cell. Biol. 20:7881-7892. http://dx.doi.org/10.1128/MCB.20.21.7881-7892.2000
7. Crick, F.H., L. Barnett, S. Brenner, and R.J. Watts-Tobin. 1961. General nature of the genetic code for proteins. Nature. 192:1227-1232. http://dx.doi.org/10.1038/1921227a0
8. Dahlberg, J.E., and E. Lund. 2004. Does protein synthesis occur in the nucleus? Curr. Opin. Cell Biol. 16:335-338. http://dx.doi.org/10.1016/j.ceb.2004.03.006
9. David, A., B.P. Dolan, H.D. Hickman, J.J. Knowlton, G. Clavarino, P. Pierre, J.R. Bennink, and J.W. Yewdell. 2012. Nuclear translation visualized by ribosome-bound nascent chain puromycylation. J. Cell Biol. 197:45-57.
10. de Turris, V., P. Nicholson, R.Z. Orozco, R.H. Singer, and O. Mühlemann. 2011. Cotranscriptional effect of a premature termination codon revealed by live-cell imaging. RNA. 17:2094-2107. http://dx.doi.org/10.1261/rna.02918111
11. Ford, C.L., L. Randal-Whitis, and S.R. Ellis. 1999. Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Res. 59:704-710
12. Goidl, J.A., D. Canaani, M. Boublik, H. Weissbach, and H. Dickerman. 1975. Polyanion-induced release of polyribosomes from HeLa cell nuclei. J. Biol. Chem. 250:9198-9205.
13. Iborra, F.J., D.A. Jackson, and P.R. Cook. 2001. Coupled transcription and translation within nuclei of mammalian cells. Science. 293:1139-1142. http://dx.doi.org/10.1126/science.1061216
14. Iborra, F.J., A.E. Escargueil, K.Y. Kwek, A. Akoulitchev, and P.R. Cook. 2004. Molecular cross-talk between the transcription, translation, and nonsensemediated decay machineries. J. Cell Sci. 117:899-906. http://dx.doi.org/10.1242/jcs.00933
15. Ingolia, N.T., S. Ghaemmaghami, J.R. Newman, and J.S. Weissman. 2009. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science. 324:218-223. http://dx.doi.org/10.1126/science.1168978
16. Kislauskis, E.H., X. Zhu, and R.H. Singer. 1997. β-Actin messenger RNA localization and protein synthesis augment cell motility. J. Cell Biol. 136:1263-1270. http://dx.doi.org/10.1083/jcb.136.6.1263
17. LeBlanc, J.J., and K.L. Beemon. 2004. Unspliced Rous sarcoma virus genomic RNAs are translated and subjected to nonsense-mediated mRNA decay before packaging. J. Virol. 78:5139-5146. http://dx.doi.org/10.1128/JVI.78.10.5139-5146.2004
18. Lund, E., and J.E. Dahlberg. 1998. Proofreading and aminoacylation of tRNAs before export from the nucleus. Science. 282:2082-2085. http://dx.doi.org/10.1126/science.282.5396.2082
19. Nathanson, L., T. Xia, and M.P. Deutscher. 2003. Nuclear protein synthesis: a re-evaluation. RNA. 9:9-13. http://dx.doi.org/10.1261/rna.2990203
20. Reid, D.W., and C.V. Nicchitta. 2012. Primary role for endoplasmic reticulumbound ribosomes in cellular translation identified by ribosome profiling. J. Biol. Chem. 287:5518-5527. http://dx.doi.org/10.1074/jbc.M111.312280
21. Sharp, J.A., J.J. Plant, T.K. Ohsumi, M. Borowsky, and M.D. Blower. 2011. Functional analysis of the microtubule-interacting transcriptome. Mol. Biol. Cell. 22:4312-4323. http://dx.doi.org/10.1091/mbc.E11-07-0629
22. Udem, S.A., and J.R. Warner. 1973. The cytoplasmic maturation of a ribosomal precursor ribonucleic acid in yeast. J. Biol. Chem. 248:1412-1416.