Reversal of profound and "deep" residual rocuronium-induced neuromuscular blockade by sugammadex: A neurophysiological study

Minerva Anestesiologica

Volumn 78, Issue 5, 2012, Pages 542-549

  Pavoni, V ^a   Gianesello, L ^a   de Scisciolo, G ^a   Provvedi, E ^a   Horton, D ^b   Barbagli, R ^a   Conti, P ^a   Conti, R ^a   Giunta, F ^c  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

Sugammadex neuromuscular blockade neurophysiology

Indexed keywords

ROCURONIUM; SUGAMMADEX;

ADULT; AGED; ARM; ARTICLE; CLINICAL ARTICLE; DIAPHRAGM; DRUG EFFICACY; ELECTROMYOGRAPHY; ELECTROSTIMULATION; EVOKED MUSCLE RESPONSE; FEMALE; HUMAN; LEG; MALE; NERVE STIMULATION; NEUROMONITORING; NEUROMUSCULAR BLOCKING; NEUROPHYSIOLOGY; PROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; ANDROSTANOLS; FEMALE; GAMMA-CYCLODEXTRINS; HUMANS; MALE; MIDDLE AGED; NERVOUS SYSTEM PHYSIOLOGICAL PROCESSES; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR NONDEPOLARIZING AGENTS; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84860298903     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Van Vlymen JM, Parlow JL. The effects of reversal of neuromuscular blockade on autonomic control in the perioperative period. Anesth Analg 1997;84:148-54.
2. Naguib M, Magboul MM, Samarkandi AH, Attia M. Adverse effects and drug interactions associated with local and regional anaesthesia. Drug Saf 1998;18:221-50.
3. Kopman AF, Yee PS, Neumann GG. Relationship of the train-of-four fade ratio to clinical signs and symptoms of residual paralysis in awake volunteers. Anesthesiology 1997;86:765-71
4. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS et al. Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit. Anesth Analg 2008;107:130-7.
5. Kovac AL. Sugammadex: the first selective binding reversal agent for neuromuscular block. J Clin Anesth 2009;21:444-53.
6. Bom A, Bradley M, Cameron K, Clark JK, Van Egmond J, Feilden H et al. A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angew Chem Int Ed Engl 2002;41:266-70.
7. Della Rocca G, Pompei L. A novel approach to reversal of neuromuscular blockade. Minerva Anestesiol 2009;75:349-51.
8. Bom A, Epemolu O, Hope F, Rutherford S, Thomson K. Selective relaxant binding agents for reversal of neuromuscular blockade. Curr Opin Pharmacol 2007;7:298-302.
9. Ali HH, Utting JE, Gray TC. Quantitative assessment of residual antidepolarizing block. Part I. Br J Anaesth 1971;43:473-7.
10. Eriksson LI. Reduced hypoxic chemosensitivity in partially paralysed man. A new property of muscle relaxants? Acta Anaesthesiol Scand 1996;40:520-3.
11. Eriksson LI, Sundman E, Olsson R, Nilsson L, Witt H, Ekberg O et al. Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans: simultaneous videomanometry and mechanomyography of awake human volunteers. Anesthesiology 1997;87:1035-43.
12. Eikermann M, Gerwing M, Hasselmann C, Fiedler G, Peters J. Impaired neuromuscular transmission after recovery of the train-of-four ratio. Acta Anaesth Scand 2007;51:226-34.
13. Eikermann M, Vogt FM, Herstreit F, Vahid-Dastgerdi M, Zenge MO, Ochterbeck C et al. The predisposition of inspiratory upper airway collapse during partial neuromuscular blockade. Am J Crit Care Med 2007;175:9-15.
14. Plaud B, Debaene B, Donati F, Marty J. Residual paralysis after emergence from anesthesia. Anesthesiology 2010;112:1013-22.
15. Duvaldestin P, Kuizenga K, Saldien V, Claudius C, Servin F, Klein J et al. A randomized, dose-response study of sugammadex given for the reversal of deep rocuronium- or vecuronium-induced neuromuscular blockade under sevoflurane anesthesia. Anesth Analg 2010;110:74-82.
16. Groudine SB, Soto R, Lien C, Drover D, Roberts K. A randomized, dose finding, phase II study of the selective relaxant binding drug, sugammadex, capable of safely reversing profound rocuronium-induced neuromuscular block. Anesth Analg 2007;104:555-62.
17. Jones RK, Caldwell JE, Brull SJ, Soto RG. Reversal of profound rocuronium induced block with sugammadex: a randomized comparison with neostigmine. Anesthesiology 2008;109:816-24.
18. Sloan TB, Erian R. Effect of vecuronium-induced neuromuscular blockade on cortical motor evoked potentials. Anesthesiology 1993;78:966-73.
19. Sloan TB, Erian R. Effect of atracurium-induced neuromuscular blockade on cortical motor evoked potentials. Anesth Analg 1993;76:979-84.
20. White PF, Tufanogullari B, Sacan O, Pavlin EG, Viegas OJ, Minkowitz HS et al. The effect of residual neuromuscular blockade on the speed of reversal with sugammadex. Anesth Analg 2009;108:846-51.
21. Simpson J, Munro PT, Graham CA. Rapid sequence intubation in the emergency department: 5 years trends. Emerg Med J 2006;23:54-6.
22. Dibble C, Maloba M. Rapid sequence induction in the emergency department by emergency medicine personnel. Emerg Med J 2006;23:62-4.
23. Puhringer F, Rex C, Sielenkamper A, Claudius C, Larsen PB, Prins ME et al. Reversal of profound, high-dose rocuronium-induced neuromuscular blockade by sugammadex at two different time points. Anesthesiology 2008;109:188-97.
24. Lee C, Jahr JS, Candiotti K, Warriner B, Zornow MH, Naguib M. Reversal of profound neuromuscular block by sugammadex administration three minutes after rocuronium: a comparison with spontaneous recovery from succinylcoline. Anesthesiology 2009;110:1020-5.
25. Benmuof JL, Dagg R, Benmuof R. Critical hemoglobin desaturation will occur before return to an unparalysed state following 1 mg/kg intravenous succinylcoline. Anesthesiology 1997;87:979-82.
26. Hayes AH, Breslin DS, Mirakhur R, Reid JE, O'Hare RA. Frequency of hemoglobin desaturation with the use of succinylcoline during rapid sequence induction of anaesthesia. Acta Anaesthesiol Scand 2001;45:746-9.
27. Hogg RMG, Lappin E, Shields MO, Hyndman E, Foster B, Mirakhur RK. Sugammadex allows the use of rocuronium in place of succinylcholine during rapid sequence induction of anaesthesia. Br J Anaesth 2010;105:726-7P.
28. Boyd SG, Rothwell JC, Cowan JMA, Webb PJ, Morley T, Asselman P et al. A method of monitoring function in corticospinal pathways during scoliosis surgery with a note on motor conduction velocities. J Neurosurg Psychiatry 1986;49:251-7.
29. Vanacker BF, Vermeyer KM, Struys MM, Reitbergen H, Vandermeersch E, Saldier V et al. Reversal of rocuroniuminduced neuromuscular block with the novel drug sugammadex is equally effective under maintenance anesthesia with propofol or sevoflurane. Anesth Analg 2007;104:563-8.
30. Di Minno RM, Abbruzzese A, Cafiero T, Guarino I, Della Rosa AR, D'Errico C et al. Evaluation of the recovery and extubation times with sugammadex: inhaled anesthesia vs TIVA/TCI. Minerva Anestesiol 2011;C005.
31. Haghighi SS, Green KD, Oro JJ, Drake RK, Kracke GR. Depressive effect of isofluorane anesthesia on motor evoked potentials. Neurosurgery 1990;26:993-7.
32. Zentner J, Albrecht T, Heuser D. Influence of halothane, enfluorane, and isofluorane on motor evoked potentials. Neurosurgery 1992;31:298-305.
33. Calancie B, Klosek J, Baier S, Green BA. Isofluorane-induced attenuation for motor evoked potentials caused by electrical motor cortex stimulation during surgery. J Neurosurg 1991;74:897-904.