Alpers syndrome: The natural history of a case highlighting neuroimaging, neuropathology, and fat metabolism

Journal of Child Neurology

Volumn 27, Issue 5, 2012, Pages 636-640

  Khan, Aneal ^a   Trevenen, Cynthia ^a   Wei, Xing Chang ^a   Sarnat, Harvey B ^a   Payne, Eric ^a   Kirton, Adam ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Alpers syndrome; ketogenic diet; mitochondrial disease; POLG1

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA CRYSTALLIN; ANTICONVULSIVE AGENT; ASPARTATE AMINOTRANSFERASE; BETA CRYSTALLIN; CORTICOSTEROID; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN; LACTIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALPERS DISEASE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ASTROCYTE; AUTOPSY; BRAIN ISCHEMIA; BRAIN NECROSIS; CASE REPORT; CHILD DEATH; CONGESTIVE HEART FAILURE; CONSCIOUSNESS DISORDER; DEVELOPMENTAL DISORDER; DIFFUSION WEIGHTED IMAGING; DISEASE COURSE; DNA SEQUENCE; FATTY LIVER; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENE; GENE DELETION; GENE MUTATION; GLIOSIS; HUMAN; INFANT; KETOGENIC DIET; LIPID METABOLISM; LIVER CELL; LIVER FUNCTION TEST; MALE; MICROSCOPY; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL GENOME; MITOCHONDRION; MUSCLE HYPOTONIA; NERVE CELL DEGENERATION; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGODENDROGLIA; POLG1 GENE; PRIORITY JOURNAL; RESPIRATORY FAILURE; REVIEW; SENSORIMOTOR CORTEX; TRANSCRANIAL MAGNETIC STIMULATION;

BIOPSY; DIFFUSE CEREBRAL SCLEROSIS OF SCHILDER; DNA-DIRECTED DNA POLYMERASE; FRONTAL LOBE; HUMANS; INFANT; LACTIC ACID; LIPID METABOLISM; LIVER; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MUTATION; NEUROIMAGING;

EID: 84860296179     PISSN: 08830738     EISSN: 17088283     Source Type: Journal    
DOI: 10.1177/0883073811423973     Document Type: Review

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