-
1
-
-
0015749593
-
A general theory of carcinogenesis
-
Comings DE. A general theory of carcinogenesis. Proc Natl AcadSci USA 1973; 70(12): 3324-8.
-
(1973)
Proc Natl AcadSci USA
, vol.70
, Issue.12
, pp. 3324-3328
-
-
Comings, D.E.1
-
2
-
-
78651011011
-
An experimental study of the initiatingstate of carcinogenesis, and a re-examination of the somatic cellmutation theory of cancer
-
Berenblum I, Shubik P. An experimental study of the initiatingstate of carcinogenesis, and a re-examination of the somatic cellmutation theory of cancer. Br J Cancer 1949; 3(1): 109-18.
-
(1949)
Br J Cancer
, vol.3
, Issue.1
, pp. 109-118
-
-
Berenblum, I.1
Shubik, P.2
-
3
-
-
84934075519
-
Somatic mutation theory
-
Sorsa M. Somatic mutation theory. J Toxicol Environ Health 1980;6(5-6): 977-82.
-
(1980)
J Toxicol Environ Health
, vol.6
, Issue.5-6
, pp. 977-982
-
-
Sorsa, M.1
-
4
-
-
7044264244
-
The somatic mutation theory of cancer:Growing problems with the paradigm?
-
Soto AM, Sonnenschein C. The somatic mutation theory of cancer:growing problems with the paradigm? Bioessays 2004; 26(10):1097-107.
-
(2004)
Bioessays
, vol.26
, Issue.10
, pp. 1097-1107
-
-
Soto, A.M.1
Sonnenschein, C.2
-
6
-
-
0000817082
-
The behaviour of chicken sarcoma implantedin the developing embryo
-
Murphy JB, Rous P. The behaviour of chicken sarcoma implantedin the developing embryo. J Exp Med 1912; 15(2): 119-32.
-
(1912)
J Exp Med
, vol.15
, Issue.2
, pp. 119-132
-
-
Murphy, J.B.1
Rous, P.2
-
7
-
-
85012798610
-
A transmissible avian neoplasm (Sarcoma of the commonfowl)
-
Rous P. A transmissible avian neoplasm (Sarcoma of the commonfowl). J Exp Med 1910; 12(5): 696-705.
-
(1910)
J Exp Med
, vol.12
, Issue.5
, pp. 696-705
-
-
Rous, P.1
-
8
-
-
57049171306
-
Oncogenesis by retroviruses: Old andnew paradigms
-
Maeda N, Fan H, Yoshikai Y. Oncogenesis by retroviruses: old andnew paradigms. Rev Med Virol 2008; 18(6): 387-405.
-
(2008)
Rev Med Virol
, vol.18
, Issue.6
, pp. 387-405
-
-
Maeda, N.1
Fan, H.2
Yoshikai, Y.3
-
9
-
-
7944231535
-
The road to Src
-
Martin GS. The road to Src. Oncogene 2004; 23(48): 7910-7.
-
(2004)
Oncogene
, vol.23
, Issue.48
, pp. 7910-7917
-
-
Martin, G.S.1
-
10
-
-
52049104666
-
The history of Cancer Research: Introducingan AACR Centennial series
-
Weinstein IB, Case K. The history of Cancer Research: introducingan AACR Centennial series. Cancer Res 2008; 68(17): 6861-2.
-
(2008)
Cancer Res
, vol.68
, Issue.17
, pp. 6861-6862
-
-
Weinstein, I.B.1
Case, K.2
-
11
-
-
0017374040
-
Experimental study of the pathogenesisof carcinoma
-
Yamagiwa K, Ichikawa K. Experimental study of the pathogenesisof carcinoma. CA Cancer J Clin 1977; 27(3): 174-81.
-
(1977)
CA Cancer J Clin
, vol.27
, Issue.3
, pp. 174-181
-
-
Yamagiwa, K.1
Ichikawa, K.2
-
12
-
-
13444273224
-
Nature and nurture-lessons from chemical carcinogenesis
-
Luch A. Nature and nurture-lessons from chemical carcinogenesis. Nat Rev Cancer 2005; 5(2): 113-25.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.2
, pp. 113-125
-
-
Luch, A.1
-
13
-
-
0021120244
-
Current knowledge of mechanisms of viral carcinogenesis
-
Rapp F. Current knowledge of mechanisms of viral carcinogenesis. Crit Rev Toxicol 1984; 13(2): 197-204.
-
(1984)
Crit Rev Toxicol
, vol.13
, Issue.2
, pp. 197-204
-
-
Rapp, F.1
-
14
-
-
0015591140
-
An improved bacterial test systemfor the detection and classification of mutagens and carcinogens
-
Ames BN, Lee FD, Durston WE. An improved bacterial test systemfor the detection and classification of mutagens and carcinogens. Proc Natl Acad Sci USA 1973; 70(3): 782-6.
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, Issue.3
, pp. 782-786
-
-
Ames, B.N.1
Lee, F.D.2
Durston, W.E.3
-
15
-
-
0000179727
-
Carcinogens aremutagens: A simple test system combining liver homogenates foractivation and bacteria for detection
-
Ames BN, Durston WE, Yamasaki E, Lee FD. Carcinogens aremutagens: a simple test system combining liver homogenates foractivation and bacteria for detection. Proc Natl Acad Sci USA1973; 70(8): 2281-5.
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, Issue.8
, pp. 2281-2285
-
-
Ames, B.N.1
Durston, W.E.2
Yamasaki, E.3
Lee, F.D.4
-
16
-
-
0016358028
-
A combined bacterial and liver test system for detectionand classification of carcinogens as mutagens
-
Ames BN. A combined bacterial and liver test system for detectionand classification of carcinogens as mutagens. Genetics 1974;78(1): 91-5.
-
(1974)
Genetics
, vol.78
, Issue.1
, pp. 91-95
-
-
Ames, B.N.1
-
17
-
-
0016810293
-
Hair dyes are mutagenic:Identification of a variety of mutagenic ingredients
-
Ames BN, Kammen HO, Yamasaki E. Hair dyes are mutagenic:identification of a variety of mutagenic ingredients. Proc Natl AcadSci USA 1975; 72(6): 2423-7.
-
(1975)
Proc Natl AcadSci USA
, vol.72
, Issue.6
, pp. 2423-2427
-
-
Ames, B.N.1
Kammen, H.O.2
Yamasaki, E.3
-
18
-
-
0343221928
-
A simple method for the detection ofmutagens in urine: Studies with the carcinogen 2-acetylaminofluorene
-
Durston WE, Ames BN. A simple method for the detection ofmutagens in urine: studies with the carcinogen 2-acetylaminofluorene. Proc Natl Acad Sci USA 1974; 71(3): 737-41.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, Issue.3
, pp. 737-741
-
-
Durston, W.E.1
Ames, B.N.2
-
19
-
-
0006899586
-
Detection of mutagenic activityin cigarette smoke condensates
-
Kier LD, Yamasaki E, Ames BN. Detection of mutagenic activityin cigarette smoke condensates. Proc Natl Acad Sci USA 1974;71(10): 4159-63.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, Issue.10
, pp. 4159-4163
-
-
Kier, L.D.1
Yamasaki, E.2
Ames, B.N.3
-
20
-
-
0027848672
-
DNA lesions, inducible DNArepair, and cell division: Three key factors in mutagenesis and carcinogenesis
-
Ames BN, Shigenaga MK, Gold LS. DNA lesions, inducible DNArepair, and cell division: three key factors in mutagenesis and carcinogenesis. Environ Health Perspect 1993; 101 Suppl 5: 35-44.
-
(1993)
Environ Health Perspect
, vol.101
, Issue.SUPPL. 5
, pp. 35-44
-
-
Ames, B.N.1
Shigenaga, M.K.2
Gold, L.S.3
-
21
-
-
70349758510
-
Src kinases as therapeutic targets forcancer
-
Kim LC, Song L, Haura EB. Src kinases as therapeutic targets forcancer. Nat Rev Clin Oncol 2009; 6(10): 587-95.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, Issue.10
, pp. 587-595
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
22
-
-
48749108800
-
Deregulation of signalingpathways in acute myeloid leukemia
-
Scholl C, Gilliland DG, Frohling S. Deregulation of signalingpathways in acute myeloid leukemia. Semin Oncol 2008; 35(4):336-45.
-
(2008)
Semin Oncol
, vol.35
, Issue.4
, pp. 336-345
-
-
Scholl, C.1
Gilliland, D.G.2
Frohling, S.3
-
23
-
-
27744465418
-
The IGF-I/IGF-I receptorpathway: Implications in the Pathophysiology of Thyroid Cancer
-
Ciampolillo A, De TC, Giorgino F. The IGF-I/IGF-I receptorpathway: Implications in the Pathophysiology of Thyroid Cancer. Curr Med Chem 2005; 12(24): 2881-91.
-
(2005)
Curr Med Chem
, vol.12
, Issue.24
, pp. 2881-2891
-
-
Ciampolillo, A.1
De, T.C.2
Giorgino, F.3
-
24
-
-
33845334175
-
Actions of TGF-beta as tumor suppressorand pro-metastatic factor in human cancer
-
Pardali K, Moustakas A. Actions of TGF-beta as tumor suppressorand pro-metastatic factor in human cancer. Biochim Biophys Acta2007; 1775(1): 21-62.
-
(2007)
Biochim Biophys Acta
, vol.1775
, Issue.1
, pp. 21-62
-
-
Pardali, K.1
Moustakas, A.2
-
25
-
-
0033614998
-
Creation of human tumour cells with definedgenetic elements
-
Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, BrooksMW, Weinberg RA. Creation of human tumour cells with definedgenetic elements. Nature 1999; 400(6743): 464-8.
-
(1999)
Nature
, vol.400
, Issue.6743
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
26
-
-
0036559896
-
Papillomaviruses and cancer: From basic studies to clinicalapplication
-
zur HH. Papillomaviruses and cancer: from basic studies to clinicalapplication. Nat Rev Cancer 2002; 2(5): 342-50.
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.5
, pp. 342-350
-
-
Zur, H.H.1
-
27
-
-
0022368305
-
Specific growth response ofras-transformed embryo fibroblasts to tumour promoters
-
Dotto GP, Parada LF, Weinberg RA. Specific growth response ofras-transformed embryo fibroblasts to tumour promoters. Nature1985; 318(6045): 472-5.
-
(1985)
Nature
, vol.318
, Issue.6045
, pp. 472-475
-
-
Dotto, G.P.1
Parada, L.F.2
Weinberg, R.A.3
-
28
-
-
67649939163
-
The increasing complexity of the cancerstem cell paradigm
-
Rosen JM, Jordan CT. The increasing complexity of the cancerstem cell paradigm. Science 2009; 324(5935): 1670-3.
-
(2009)
Science
, vol.324
, Issue.5935
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
29
-
-
0028091194
-
A cell initiating human acutemyeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acutemyeloid leukaemia after transplantation into SCID mice. Nature1994; 367(6464): 645-8.
-
(1994)
Nature
, vol.367
, Issue.6464
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
-
30
-
-
52549087785
-
Cancer stem cells in solid tumours:Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours:accumulating evidence and unresolved questions. Nat Rev Cancer2008; 8(10): 755-68.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.10
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
31
-
-
0030789242
-
Human acute myeloid leukemia is organized asa hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized asa hierarchy that originates from a primitive hematopoietic cell. NatMed 1997; 3(7): 730-7.
-
(1997)
NatMed
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
32
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, ito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. ProcNatl Acad Sci USA 2003; 100(7): 3983-8.
-
(2003)
ProcNatl Acad Sci USA
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Ito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
33
-
-
0141842674
-
Identification of a cancerstem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancerstem cell in human brain tumors. Cancer Res 2003; 63(18): 5821-8.
-
(2003)
Cancer Res
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
34
-
-
9244241576
-
Identification of humanbrain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, et al. Identification of humanbrain tumour initiating cells. Nature 2004; 432(7015): 396-401.
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
35
-
-
73649102464
-
EZH2 isessential for glioblastoma cancer stem cell maintenance
-
Suva ML, Riggi N, Janiszewska M, Radovanovic I, et al. EZH2 isessential for glioblastoma cancer stem cell maintenance. CancerRes 2009; 69(24): 9211-8.
-
(2009)
CancerRes
, vol.69
, Issue.24
, pp. 9211-9218
-
-
Suva, M.L.1
Riggi, N.2
Janiszewska, M.3
Radovanovic, I.4
-
36
-
-
57349143739
-
Efficient tumour formation by single human melanomacells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanomacells. Nature 2008; 456(7222): 593-8.
-
(2008)
Nature
, vol.456
, Issue.7222
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
37
-
-
33846095137
-
Identification andexpansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al. Identification andexpansion of human colon-cancer-initiating cells. Nature 2007;445(7123): 111-5.
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
38
-
-
33846100356
-
A human colon cancercell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancercell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445(7123): 106-10.
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
40
-
-
34948896045
-
Mesenchymal stem cellswithin tumour stroma promote breast cancer metastasis
-
Karnoub AE, Dash AB, Vo AP, et al. Mesenchymal stem cellswithin tumour stroma promote breast cancer metastasis. Nature2007; 449(7162): 557-63.
-
(2007)
Nature
, vol.449
, Issue.7162
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
-
41
-
-
67650999875
-
The basics of epithelial-mesenchymaltransition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymaltransition. J Clin Invest 2009; 119(6): 1420-8.
-
(2009)
J Clin Invest
, vol.119
, Issue.6
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
42
-
-
43049165453
-
The epithelial-mesenchymaltransition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymaltransition generates cells with properties of stem cells. Cell 2008;133(4): 704-15.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
43
-
-
0345255908
-
Nodal signaling in vertebrate development
-
Schier AF. Nodal signaling in vertebrate development. Annu RevCell Dev Biol 2003; 19: 589-621.
-
(2003)
Annu RevCell Dev Biol
, vol.19
, pp. 589-621
-
-
Schier, A.F.1
-
44
-
-
33746846469
-
Embryonicand tumorigenic pathways converge via Nodal signaling: Role inmelanoma aggressiveness
-
Topczewska JM, Postovit LM, Margaryan NV, et al. Embryonicand tumorigenic pathways converge via Nodal signaling: role inmelanoma aggressiveness. Nat Med 2006; 12(8): 925-32.
-
(2006)
Nat Med
, vol.12
, Issue.8
, pp. 925-932
-
-
Topczewska, J.M.1
Postovit, L.M.2
Margaryan, N.V.3
-
45
-
-
33748043969
-
Influence of themicroenvironment on melanoma cell fate determination and phenotype
-
Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. Influence of themicroenvironment on melanoma cell fate determination and phenotype. Cancer Res 2006; 66(16): 7833-6.
-
(2006)
Cancer Res
, vol.66
, Issue.16
, pp. 7833-7836
-
-
Postovit, L.M.1
Seftor, E.A.2
Seftor, R.E.3
Hendrix, M.J.4
-
46
-
-
41949142373
-
Human embryonicstem cell microenvironment suppresses the tumorigenic phenotypeof aggressive cancer cells
-
Postovit LM, Margaryan NV, Seftor EA, et al. Human embryonicstem cell microenvironment suppresses the tumorigenic phenotypeof aggressive cancer cells. Proc Natl Acad Sci USA 2008; 105(11):4329-34.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.11
, pp. 4329-4334
-
-
Postovit, L.M.1
Margaryan, N.V.2
Seftor, E.A.3
-
47
-
-
79958239867
-
Reactivation ofembryonic nodal signaling is associated with tumor progressionand promotes the growth of prostate cancer cells
-
Lawrence MG, Margaryan NV, Loessner D, et al. Reactivation ofembryonic nodal signaling is associated with tumor progressionand promotes the growth of prostate cancer cells. Prostate 2011.
-
(2011)
Prostate
-
-
Lawrence, M.G.1
Margaryan, N.V.2
Loessner, D.3
-
48
-
-
78650963929
-
Dynamics between stem cells, niche, and progeny in the hair follicle
-
Hsu YC, Pasolli HA, Fuchs E. Dynamics between stem cells, niche, and progeny in the hair follicle. Cell 2011; 144(1): 92-105.
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 92-105
-
-
Hsu, Y.C.1
Pasolli, H.A.2
Fuchs, E.3
-
49
-
-
0032953231
-
A common human skintumour is caused by activating mutations in beta-catenin
-
Chan EF, Gat U, McNiff JM, Fuchs E. A common human skintumour is caused by activating mutations in beta-catenin. Nat Genet1999; 21(4): 410-3.
-
(1999)
Nat Genet
, vol.21
, Issue.4
, pp. 410-413
-
-
Chan, E.F.1
Gat, U.2
McNiff, J.M.3
Fuchs, E.4
-
50
-
-
79955681163
-
The Intestinal StemCell Signature Identifies Colorectal Cancer Stem Cells and PredictsDisease Relapse
-
Merlos-Suarez A, Barriga FM, Jung P, et al. The Intestinal StemCell Signature Identifies Colorectal Cancer Stem Cells and PredictsDisease Relapse. Cell Stem Cell 2011; 8(5): 511-24.
-
(2011)
Cell Stem Cell
, vol.8
, Issue.5
, pp. 511-524
-
-
Merlos-Suarez, A.1
Barriga, F.M.2
Jung, P.3
-
51
-
-
38349165576
-
Identification of cellsinitiating human melanomas
-
Schatton T, Murphy GF, Frank NY, et al. Identification of cellsinitiating human melanomas. Nature 2008; 451(7176): 345-9.
-
(2008)
Nature
, vol.451
, Issue.7176
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
-
52
-
-
77951235482
-
Cancer stem cells sustaining thegrowth of mouse melanoma are not rare
-
Zhong Y, Guan K, Zhou C, et al. Cancer stem cells sustaining thegrowth of mouse melanoma are not rare. Cancer Lett 2009; 292(1):17-23.
-
(2009)
Cancer Lett
, vol.292
, Issue.1
, pp. 17-23
-
-
Zhong, Y.1
Guan, K.2
Zhou, C.3
-
53
-
-
69349100179
-
Suppression of inducedpluripotent stem cell generation by the p53-p21 pathway
-
Hong H, Takahashi K, Ichisaka T, et al. Suppression of inducedpluripotent stem cell generation by the p53-p21 pathway. Nature2009; 460(7259): 1132-5.
-
(2009)
Nature
, vol.460
, Issue.7259
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
-
54
-
-
18644373013
-
Telomerase contributesto tumorigenesis by a telomere length-independent mechanism
-
Stewart SA, Hahn WC, O'Connor BF, et al. Telomerase contributesto tumorigenesis by a telomere length-independent mechanism. Proc Natl Acad Sci USA 2002; 99(20): 12606-11.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.20
, pp. 12606-12611
-
-
Stewart, S.A.1
Hahn, W.C.2
O'Connor, B.F.3
-
55
-
-
77949808547
-
Theembryonic morphogen, Nodal, is associated with channel-likestructures in human malignant melanoma xenografts
-
McAllister JC, Zhan Q, Weishaupt C, Hsu MY, Murphy GF. Theembryonic morphogen, Nodal, is associated with channel-likestructures in human malignant melanoma xenografts. J CutanPathol 2010; 37 Suppl 1: 19-25.
-
(2010)
J CutanPathol
, vol.37
, Issue.SUPPL. 1
, pp. 19-25
-
-
McAllister, J.C.1
Zhan, Q.2
Weishaupt, C.3
Hsu, M.Y.4
Murphy, G.F.5
-
56
-
-
0038143145
-
Vasculogenic mimicryand tumour-cell plasticity: Lessons from melanoma
-
Hendrix MJ, Seftor EA, Hess AR, Seftor RE. Vasculogenic mimicryand tumour-cell plasticity: lessons from melanoma. Nat RevCancer 2003; 3(6): 411-21.
-
(2003)
Nat RevCancer
, vol.3
, Issue.6
, pp. 411-421
-
-
Hendrix, M.J.1
Seftor, E.A.2
Hess, A.R.3
Seftor, R.E.4
-
57
-
-
0037081174
-
Hemodynamics invasculogenic mimicry and angiogenesis of inflammatory breastcancer xenograft
-
Shirakawa K, Kobayashi H, Heike Y, et al. Hemodynamics invasculogenic mimicry and angiogenesis of inflammatory breastcancer xenograft. Cancer Res 2002; 62(2): 560-6.
-
(2002)
Cancer Res
, vol.62
, Issue.2
, pp. 560-566
-
-
Shirakawa, K.1
Kobayashi, H.2
Heike, Y.3
-
58
-
-
0037636378
-
The clinical significanceof tumor cell-lined vasculature in ovarian carcinoma: Implicationsfor anti-vasculogenic therapy
-
Sood AK, Fletcher MS, Zahn CM, et al. The clinical significanceof tumor cell-lined vasculature in ovarian carcinoma: implicationsfor anti-vasculogenic therapy. Cancer Biol Ther 2002; 1(6): 661-4.
-
(2002)
Cancer Biol Ther
, vol.1
, Issue.6
, pp. 661-664
-
-
Sood, A.K.1
Fletcher, M.S.2
Zahn, C.M.3
-
59
-
-
0037083432
-
Prostatic tumor cell plasticityinvolves cooperative interactions of distinct phenotypic subpopulations:Role in vasculogenic mimicry
-
Sharma N, Seftor RE, Seftor EA, et al. Prostatic tumor cell plasticityinvolves cooperative interactions of distinct phenotypic subpopulations:role in vasculogenic mimicry. Prostate 2002; 50(3):189-201.
-
(2002)
Prostate
, vol.50
, Issue.3
, pp. 189-201
-
-
Sharma, N.1
Seftor, R.E.2
Seftor, E.A.3
-
60
-
-
18244378841
-
Vascular phenotype inangiogenic and non-angiogenic lung non-small cell carcinomas
-
Passalidou E, Trivella M, Singh N, et al. Vascular phenotype inangiogenic and non-angiogenic lung non-small cell carcinomas. BrJ Cancer 2002; 86(2): 244-9.
-
(2002)
BrJ Cancer
, vol.86
, Issue.2
, pp. 244-249
-
-
Passalidou, E.1
Trivella, M.2
Singh, N.3
-
61
-
-
70450198396
-
Epithelialmesenchymaltransitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelialmesenchymaltransitions in development and disease. Cell 2009;139(5): 871-90.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
62
-
-
22144464519
-
Twist induces an epithelial-mesenchymaltransition to facilitate tumor metastasis
-
Karreth F, Tuveson DA. Twist induces an epithelial-mesenchymaltransition to facilitate tumor metastasis. Cancer Biol Ther 2004;3(11): 1058-9.
-
(2004)
Cancer Biol Ther
, vol.3
, Issue.11
, pp. 1058-1059
-
-
Karreth, F.1
Tuveson, D.A.2
-
63
-
-
79954576652
-
EMT and stem cell-like propertiesassociated with miR-205 and miR-200 epigenetic silencing areearly manifestations during carcinogen-induced transformation ofhuman lung epithelial cells
-
Tellez CS, Juri DE, Do K, et al. EMT and stem cell-like propertiesassociated with miR-205 and miR-200 epigenetic silencing areearly manifestations during carcinogen-induced transformation ofhuman lung epithelial cells. Cancer Res 2011; 71(8): 3087-97.
-
(2011)
Cancer Res
, vol.71
, Issue.8
, pp. 3087-3097
-
-
Tellez, C.S.1
Juri, D.E.2
Do, K.3
-
64
-
-
77957262381
-
Core epithelial-tomesenchymaltransition interactome gene-expression signature isassociated with claudin-low and metaplastic breast cancer subtypes
-
Taube JH, Herschkowitz JI, Komurov K, et al. Core epithelial-tomesenchymaltransition interactome gene-expression signature isassociated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci USA 2010; 107(35): 15449-54.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.35
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
-
65
-
-
63049123066
-
Transitions between epithelial and mesenchymalstates: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymalstates: acquisition of malignant and stem cell traits. NatRev Cancer 2009; 9(4): 265-73.
-
(2009)
NatRev Cancer
, vol.9
, Issue.4
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
66
-
-
55249126800
-
The role of endothelial-tomesenchymaltransition in cancer progression
-
Potenta S, Zeisberg E, Kalluri R. The role of endothelial-tomesenchymaltransition in cancer progression. Br J Cancer 2008;99(9): 1375-9.
-
(2008)
Br J Cancer
, vol.99
, Issue.9
, pp. 1375-1379
-
-
Potenta, S.1
Zeisberg, E.2
Kalluri, R.3
-
67
-
-
0034235433
-
Slug is an essential target of TGFbeta2signaling in the developing chicken heart
-
Romano LA, Runyan RB. Slug is an essential target of TGFbeta2signaling in the developing chicken heart. Dev Biol 2000; 223(1):91-102.
-
(2000)
Dev Biol
, vol.223
, Issue.1
, pp. 91-102
-
-
Romano, L.A.1
Runyan, R.B.2
-
68
-
-
4444320851
-
Heart valve development: Endothelialcell signaling and differentiation
-
Armstrong EJ, Bischoff J. Heart valve development: endothelialcell signaling and differentiation. Circ Res 2004; 95(5): 459-70.
-
(2004)
Circ Res
, vol.95
, Issue.5
, pp. 459-470
-
-
Armstrong, E.J.1
Bischoff, J.2
-
69
-
-
77649273257
-
Renal studies provide an insightinto cardiac extracellular matrix remodeling during health and disease
-
Hertig A, Gangadhar T, Kalluri R. Renal studies provide an insightinto cardiac extracellular matrix remodeling during health and disease. J Mol Cell Cardiol 2010; 48(3): 497-503.
-
(2010)
J Mol Cell Cardiol
, vol.48
, Issue.3
, pp. 497-503
-
-
Hertig, A.1
Gangadhar, T.2
Kalluri, R.3
-
70
-
-
35948945337
-
Discoveryof endothelial to mesenchymal transition as a source for carcinomaassociatedfibroblasts
-
Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discoveryof endothelial to mesenchymal transition as a source for carcinomaassociatedfibroblasts. Cancer Res 2007; 67(21): 10123-8.
-
(2007)
Cancer Res
, vol.67
, Issue.21
, pp. 10123-10128
-
-
Zeisberg, E.M.1
Potenta, S.2
Xie, L.3
Zeisberg, M.4
Kalluri, R.5
-
71
-
-
28644432204
-
VEGFR1-positive haematopoieticbone marrow progenitors initiate the pre-metastaticniche
-
Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoieticbone marrow progenitors initiate the pre-metastaticniche. Nature 2005; 438(7069): 820-7.
-
(2005)
Nature
, vol.438
, Issue.7069
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
-
72
-
-
9144246932
-
Notch promotesepithelial-mesenchymal transition during cardiac development andoncogenic transformation
-
Timmerman LA, Grego-Bessa J, Raya A, et al. Notch promotesepithelial-mesenchymal transition during cardiac development andoncogenic transformation. Genes Dev 2004; 18(1): 99-115.
-
(2004)
Genes Dev
, vol.18
, Issue.1
, pp. 99-115
-
-
Timmerman, L.A.1
Grego-Bessa, J.2
Raya, A.3
-
73
-
-
77953160885
-
Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines
-
Meyer MJ, Fleming JM, Ali MA, Pesesky MW, Ginsburg E, VonderhaarBK. Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines. BreastCancer Res 2009; 11(6): R82.
-
(2009)
BreastCancer Res
, vol.11
, Issue.6
-
-
Meyer, M.J.1
Fleming, J.M.2
Ali, M.A.3
Pesesky, M.W.4
Ginsburg, E.5
Vonderhaar, B.K.6
-
74
-
-
78249250559
-
Phenotypic heterogeneityamong tumorigenic melanoma cells from patients that is reversibleand not hierarchically organized
-
Quintana E, Shackleton M, Foster HR, et al. Phenotypic heterogeneityamong tumorigenic melanoma cells from patients that is reversibleand not hierarchically organized. Cancer Cell 2010; 18(5):510-23.
-
(2010)
Cancer Cell
, vol.18
, Issue.5
, pp. 510-523
-
-
Quintana, E.1
Shackleton, M.2
Foster, H.R.3
-
75
-
-
43549118630
-
Role ofnodal signaling and the microenvironment underlying melanomaplasticity
-
Postovit LM, Margaryan NV, Seftor EA, Hendrix MJ. Role ofnodal signaling and the microenvironment underlying melanomaplasticity. Pigment Cell Melanoma Res 2008; 21(3): 348-57.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, Issue.3
, pp. 348-357
-
-
Postovit, L.M.1
Margaryan, N.V.2
Seftor, E.A.3
Hendrix, M.J.4
-
76
-
-
77952954910
-
Nodal promotes growth and invasionin human gliomas
-
Lee CC, Jan HJ, Lai JH, et al. Nodal promotes growth and invasionin human gliomas. Oncogene 2010; 29(21): 3110-23.
-
(2010)
Oncogene
, vol.29
, Issue.21
, pp. 3110-3123
-
-
Lee, C.C.1
Jan, H.J.2
Lai, J.H.3
-
77
-
-
34447319929
-
BMP4 induces EMT and Rho GTPase activation in human ovariancancer cells
-
Theriault BL, Shepherd TG, Mujoomdar ML, Nachtigal MW. BMP4 induces EMT and Rho GTPase activation in human ovariancancer cells. Carcinogenesis 2007; 28(6): 1153-62.
-
(2007)
Carcinogenesis
, vol.28
, Issue.6
, pp. 1153-1162
-
-
Theriault, B.L.1
Shepherd, T.G.2
Mujoomdar, M.L.3
Nachtigal, M.W.4
-
78
-
-
79951784680
-
Asymmetric celldivisions promote Notch-dependent epidermal differentiation
-
Williams SE, Beronja S, Pasolli HA, Fuchs E. Asymmetric celldivisions promote Notch-dependent epidermal differentiation. Nature2011; 470(7334): 353-8.
-
(2011)
Nature
, vol.470
, Issue.7334
, pp. 353-358
-
-
Williams, S.E.1
Beronja, S.2
Pasolli, H.A.3
Fuchs, E.4
-
79
-
-
0036714030
-
Canonical and non-canonical Wnt signaling pathwaysin Caenorhabditis elegans: Variations on a common signalingtheme
-
Korswagen HC. Canonical and non-canonical Wnt signaling pathwaysin Caenorhabditis elegans: variations on a common signalingtheme. Bioessays 2002; 24(9): 801-10.
-
(2002)
Bioessays
, vol.24
, Issue.9
, pp. 801-810
-
-
Korswagen, H.C.1
-
80
-
-
0038274073
-
Notch signaling regulates leftrightasymmetry determination by inducing Nodal expression
-
Krebs LT, Iwai N, Nonaka S, et al. Notch signaling regulates leftrightasymmetry determination by inducing Nodal expression. Genes Dev 2003; 17(10): 1207-12.
-
(2003)
Genes Dev
, vol.17
, Issue.10
, pp. 1207-1212
-
-
Krebs, L.T.1
Iwai, N.2
Nonaka, S.3
-
81
-
-
70349751655
-
Development and cancer: Atthe crossroads of Nodal and Notch signaling
-
Strizzi L, Hardy KM, Seftor EA, et al. Development and cancer: atthe crossroads of Nodal and Notch signaling. Cancer Res 2009;69(18): 7131-4.
-
(2009)
Cancer Res
, vol.69
, Issue.18
, pp. 7131-7134
-
-
Strizzi, L.1
Hardy, K.M.2
Seftor, E.A.3
-
82
-
-
57049152264
-
Emerging roles ofnodal and Cripto-1: From embryogenesis to breast cancer progression
-
Strizzi L, Postovit LM, Margaryan NV, et al. Emerging roles ofnodal and Cripto-1: from embryogenesis to breast cancer progression. Breast Dis 2008; 29: 91-103.
-
(2008)
Breast Dis
, vol.29
, pp. 91-103
-
-
Strizzi, L.1
Postovit, L.M.2
Margaryan, N.V.3
-
83
-
-
0033987913
-
Membrane-anchorage ofCripto protein by glycosylphosphatidylinositol and its distributionduring early mouse development
-
Minchiotti G, Parisi S, Liguori G, et al. Membrane-anchorage ofCripto protein by glycosylphosphatidylinositol and its distributionduring early mouse development. Mech Dev 2000; 90(2): 133-42.
-
(2000)
Mech Dev
, vol.90
, Issue.2
, pp. 133-142
-
-
Minchiotti, G.1
Parisi, S.2
Liguori, G.3
-
84
-
-
67249117804
-
Riding shotgun: A dual role for the epidermal growthfactor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking
-
Constam DB. Riding shotgun: a dual role for the epidermal growthfactor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking. Traffic 2009; 10(7): 783-91.
-
(2009)
Traffic
, vol.10
, Issue.7
, pp. 783-791
-
-
Constam, D.B.1
-
85
-
-
58249094759
-
Cripto localizesNodal at the limiting membrane of early endosomes
-
Blanchet MH, Le Good JA, Oorschot V, et al. Cripto localizesNodal at the limiting membrane of early endosomes. Sci Signal2008; 1(45): ra13.
-
(2008)
Sci Signal
, vol.1
, Issue.45
-
-
Blanchet, M.H.1
Le Good, J.A.2
Oorschot, V.3
-
86
-
-
37249000754
-
Requirement of glycosylphosphatidylinositolanchor of Cripto-1 for trans activity as aNodal co-receptor
-
Watanabe K, Hamada S, Bianco C, et al. Requirement of glycosylphosphatidylinositolanchor of Cripto-1 for trans activity as aNodal co-receptor. J Biol Chem 2007; 282(49): 35772-86.
-
(2007)
J Biol Chem
, vol.282
, Issue.49
, pp. 35772-35786
-
-
Watanabe, K.1
Hamada, S.2
Bianco, C.3
-
87
-
-
0036275653
-
Dual roles of Cripto as a ligand andcoreceptor in the nodal signaling pathway
-
Yan YT, Liu JJ, Luo Y, et al. Dual roles of Cripto as a ligand andcoreceptor in the nodal signaling pathway. Mol Cell Biol 2002;22(13): 4439-49.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.13
, pp. 4439-4449
-
-
Yan, Y.T.1
Liu, J.J.2
Luo, Y.3
-
88
-
-
0036210652
-
Cripto-1 activatesnodal-and ALK4-dependent and-independent signaling pathwaysin mammary epithelial Cells
-
Bianco C, Adkins HB, Wechselberger C, et al. Cripto-1 activatesnodal-and ALK4-dependent and-independent signaling pathwaysin mammary epithelial Cells. Mol Cell Biol 2002; 22(8): 2586-97.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.8
, pp. 2586-2597
-
-
Bianco, C.1
Adkins, H.B.2
Wechselberger, C.3
-
89
-
-
0035425463
-
The orphan receptorALK7 and the Activin receptor ALK4 mediate signaling by Nodalproteins during vertebrate development
-
Reissmann E, Jornvall H, Blokzijl A, et al. The orphan receptorALK7 and the Activin receptor ALK4 mediate signaling by Nodalproteins during vertebrate development. Genes Dev 2001; 15(15):2010-22.
-
(2001)
Genes Dev
, vol.15
, Issue.15
, pp. 2010-2022
-
-
Reissmann, E.1
Jornvall, H.2
Blokzijl, A.3
-
90
-
-
68949164494
-
Running the gauntlet: An overview of the modalitiesof travel employed by the putative morphogen Nodal
-
Constam DB. Running the gauntlet: an overview of the modalitiesof travel employed by the putative morphogen Nodal. Curr OpinGenet Dev 2009; 19(4): 302-7.
-
(2009)
Curr OpinGenet Dev
, vol.19
, Issue.4
, pp. 302-307
-
-
Constam, D.B.1
-
91
-
-
33749175620
-
Lefty at the crossroads of"stemness" and differentiative events
-
Tabibzadeh S, Hemmati-Brivanlou A. Lefty at the crossroads of"stemness" and differentiative events. Stem Cells 2006; 24(9):1998-2006.
-
(2006)
Stem Cells
, vol.24
, Issue.9
, pp. 1998-2006
-
-
Tabibzadeh, S.1
Hemmati-Brivanlou, A.2
-
92
-
-
16244407435
-
Two nodal-responsive enhancerscontrol left-right asymmetric expression of Nodal
-
Saijoh Y, Oki S, Tanaka C, et al. Two nodal-responsive enhancerscontrol left-right asymmetric expression of Nodal. Dev Dyn 2005;232(4): 1031-6.
-
(2005)
Dev Dyn
, vol.232
, Issue.4
, pp. 1031-1036
-
-
Saijoh, Y.1
Oki, S.2
Tanaka, C.3
-
93
-
-
0033564874
-
Asymmetric and node-specific nodalexpression patterns are controlled by two distinct cis-acting regulatoryelements
-
Norris DP, Robertson EJ. Asymmetric and node-specific nodalexpression patterns are controlled by two distinct cis-acting regulatoryelements. Genes Dev 1999; 13(12): 1575-88.
-
(1999)
Genes Dev
, vol.13
, Issue.12
, pp. 1575-1588
-
-
Norris, D.P.1
Robertson, E.J.2
-
94
-
-
0037598796
-
Notch activityinduces Nodal expression and mediates the establishment of leftrightasymmetry in vertebrate embryos
-
Raya A, Kawakami Y, Rodriguez-Esteban C, et al. Notch activityinduces Nodal expression and mediates the establishment of leftrightasymmetry in vertebrate embryos. Genes Dev 2003; 17(10):1213-8.
-
(2003)
Genes Dev
, vol.17
, Issue.10
, pp. 1213-1218
-
-
Raya, A.1
Kawakami, Y.2
Rodriguez-Esteban, C.3
-
95
-
-
33947667463
-
Targeting Nodalin malignant melanoma cells
-
Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. Targeting Nodalin malignant melanoma cells. Expert Opin Ther Targets 2007;11(4): 497-505.
-
(2007)
Expert Opin Ther Targets
, vol.11
, Issue.4
, pp. 497-505
-
-
Postovit, L.M.1
Seftor, E.A.2
Seftor, R.E.3
Hendrix, M.J.4
-
96
-
-
33947583623
-
Reprogramming metastatic tumour cells withembryonic microenvironments
-
Hendrix MJ, Seftor EA, Seftor RE, Kasemeier-Kulesa J, KulesaPM, Postovit LM. Reprogramming metastatic tumour cells withembryonic microenvironments. Nat Rev Cancer 2007; 7(4): 246-55.
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.4
, pp. 246-255
-
-
Hendrix, M.J.1
Seftor, E.A.2
Seftor, R.E.3
Kasemeier-Kulesa, J.4
Kulesa, P.M.5
Postovit, L.M.6
-
97
-
-
78650334835
-
Regulation of theembryonic morphogen Nodal by Notch4 facilitates manifestation ofthe aggressive melanoma phenotype
-
Hardy KM, Kirschmann DA, Seftor EA, et al. Regulation of theembryonic morphogen Nodal by Notch4 facilitates manifestation ofthe aggressive melanoma phenotype. Cancer Res 2010; 70(24):10340-50.
-
(2010)
Cancer Res
, vol.70
, Issue.24
, pp. 10340-10350
-
-
Hardy, K.M.1
Kirschmann, D.A.2
Seftor, E.A.3
-
98
-
-
35348914716
-
Target protectors reveal dampeningand balancing of Nodal agonist and antagonist by miR-430
-
Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampeningand balancing of Nodal agonist and antagonist by miR-430. Science 2007; 318(5848): 271-4.
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 271-274
-
-
Choi, W.Y.1
Giraldez, A.J.2
Schier, A.F.3
-
99
-
-
0036902759
-
Extraembryonic proteasesregulate Nodal signalling during gastrulation
-
Beck S, Le Good JA, Guzman M, et al. Extraembryonic proteasesregulate Nodal signalling during gastrulation. Nat Cell Biol 2002;4(12): 981-5.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.12
, pp. 981-985
-
-
Beck, S.1
Le Good, J.A.2
Guzman, M.3
-
100
-
-
11944267436
-
Nodal stability determinessignaling range
-
Le Good JA, Joubin K, Giraldez AJ, et al. Nodal stability determinessignaling range. Curr Biol 2005; 15(1): 31-6.
-
(2005)
Curr Biol
, vol.15
, Issue.1
, pp. 31-36
-
-
Le Good, J.A.1
Joubin, K.2
Giraldez, A.J.3
-
101
-
-
53549118575
-
Cripto recruits Furinand PACE4 and controls Nodal trafficking during proteolyticmaturation
-
Blanchet MH, Le Good JA, Mesnard D, et al. Cripto recruits Furinand PACE4 and controls Nodal trafficking during proteolyticmaturation. EMBO J 2008; 27(19): 2580-91.
-
(2008)
EMBO J
, vol.27
, Issue.19
, pp. 2580-2591
-
-
Blanchet, M.H.1
Le Good, J.A.2
Mesnard, D.3
-
102
-
-
30344486984
-
Flotillin-1 defines a clathrinindependentendocytic pathway in mammalian cells
-
Glebov OO, Bright NA, Nichols BJ. Flotillin-1 defines a clathrinindependentendocytic pathway in mammalian cells. Nat Cell Biol2006; 8(1): 46-54.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.1
, pp. 46-54
-
-
Glebov, O.O.1
Bright, N.A.2
Nichols, B.J.3
-
103
-
-
33947255616
-
Internalization and traffickingof cell surface proteoglycans and proteoglycan-bindingligands
-
Payne CK, Jones SA, Chen C, Zhuang X. Internalization and traffickingof cell surface proteoglycans and proteoglycan-bindingligands. Traffic 2007; 8(4): 389-401.
-
(2007)
Traffic
, vol.8
, Issue.4
, pp. 389-401
-
-
Payne, C.K.1
Jones, S.A.2
Chen, C.3
Zhuang, X.4
-
104
-
-
34250851923
-
Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding
-
Frick M, Bright NA, Riento K, Bray A, Merrified C, Nichols BJ. Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding. Curr Biol 2007;17(13): 1151-6.
-
(2007)
Curr Biol
, vol.17
, Issue.13
, pp. 1151-1156
-
-
Frick, M.1
Bright, N.A.2
Riento, K.3
Bray, A.4
Merrified, C.5
Nichols, B.J.6
-
105
-
-
0035947301
-
Nodal signals to Smads through Criptodependentand Cripto-independent mechanisms
-
Yeo C, Whitman M. Nodal signals to Smads through Criptodependentand Cripto-independent mechanisms. Mol Cell 2001;7(5): 949-57.
-
(2001)
Mol Cell
, vol.7
, Issue.5
, pp. 949-957
-
-
Yeo, C.1
Whitman, M.2
-
106
-
-
3242683132
-
A gene network establishing polarity in theearly mouse embryo
-
Ang SL, Constam DB. A gene network establishing polarity in theearly mouse embryo. Semin Cell Dev Biol 2004; 15(5): 555-61.
-
(2004)
Semin Cell Dev Biol
, vol.15
, Issue.5
, pp. 555-561
-
-
Ang, S.L.1
Constam, D.B.2
-
107
-
-
0027510084
-
Nodal is anovel TGF-beta-like gene expressed in the mouse node during gastrulation
-
Zhou X, Sasaki H, Lowe L, Hogan BL, Kuehn MR. Nodal is anovel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature 1993; 361(6412): 543-7.
-
(1993)
Nature
, vol.361
, Issue.6412
, pp. 543-547
-
-
Zhou, X.1
Sasaki, H.2
Lowe, L.3
Hogan, B.L.4
Kuehn, M.R.5
-
108
-
-
0029993646
-
Relationship between asymmetricnodal expression and the direction of embryonic turning
-
Collignon J, Varlet I, Robertson EJ. Relationship between asymmetricnodal expression and the direction of embryonic turning. Nature 1996; 381(6578): 155-8.
-
(1996)
Nature
, vol.381
, Issue.6578
, pp. 155-158
-
-
Collignon, J.1
Varlet, I.2
Robertson, E.J.3
-
109
-
-
0029049830
-
A nodal-relatedgene defines a physical and functional domain within the Spemannorganizer
-
Smith WC, McKendry R, Ribisi S Jr, Harland RM. A nodal-relatedgene defines a physical and functional domain within the Spemannorganizer. Cell 1995; 82(1): 37-46.
-
(1995)
Cell
, vol.82
, Issue.1
, pp. 37-46
-
-
Smith, W.C.1
McKendry, R.2
Ribisi Jr., S.3
Harland, R.M.4
-
110
-
-
33745612029
-
The left-right axis in the mouse: Fromorigin to morphology
-
Shiratori H, Hamada H. The left-right axis in the mouse: fromorigin to morphology. Development 2006; 133(11): 2095-104.
-
(2006)
Development
, vol.133
, Issue.11
, pp. 2095-2104
-
-
Shiratori, H.1
Hamada, H.2
-
111
-
-
14244262504
-
Nodal inhibits differentiationof human embryonic stem cells along the neuroectodermal defaultpathway
-
Vallier L, Reynolds D, Pedersen RA. Nodal inhibits differentiationof human embryonic stem cells along the neuroectodermal defaultpathway. Dev Biol 2004; 275(2): 403-21.
-
(2004)
Dev Biol
, vol.275
, Issue.2
, pp. 403-421
-
-
Vallier, L.1
Reynolds, D.2
Pedersen, R.A.3
-
112
-
-
16244400050
-
TGFbeta/activin/nodal signaling is necessary for the maintenanceof pluripotency in human embryonic stem cells
-
James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenanceof pluripotency in human embryonic stem cells. Development2005; 132(6): 1273-82.
-
(2005)
Development
, vol.132
, Issue.6
, pp. 1273-1282
-
-
James, D.1
Levine, A.J.2
Besser, D.3
Hemmati-Brivanlou, A.4
-
113
-
-
67650096520
-
Activin/Nodal signallingmaintains pluripotency by controlling Nanog expression
-
Vallier L, Mendjan S, Brown S, et al. Activin/Nodal signallingmaintains pluripotency by controlling Nanog expression. Development2009; 136(8): 1339-49.
-
(2009)
Development
, vol.136
, Issue.8
, pp. 1339-1349
-
-
Vallier, L.1
Mendjan, S.2
Brown, S.3
-
114
-
-
37349052866
-
Inhibition of Activin/Nodal signaling promotes specificationof human embryonic stem cells into neuroectoderm
-
Smith JR, Vallier L, Lupo G, Alexander M, Harris WA, PedersenRA. Inhibition of Activin/Nodal signaling promotes specificationof human embryonic stem cells into neuroectoderm. Dev Biol2008; 313(1): 107-17.
-
(2008)
Dev Biol
, vol.313
, Issue.1
, pp. 107-117
-
-
Smith, J.R.1
Vallier, L.2
Lupo, G.3
Alexander, M.4
Harris, W.A.5
Pedersen, R.A.6
-
115
-
-
70350191753
-
Activin/Nodal inhibitionalone accelerates highly efficient neural conversion from humanembryonic stem cells and imposes a caudal positional identity
-
Patani R, Compston A, Puddifoot CA, et al. Activin/Nodal inhibitionalone accelerates highly efficient neural conversion from humanembryonic stem cells and imposes a caudal positional identity. PLoS One 2009; 4(10): e7327.
-
(2009)
PLoS One
, vol.4
, Issue.10
-
-
Patani, R.1
Compston, A.2
Puddifoot, C.A.3
-
116
-
-
33744990640
-
A threedimensionalmodel to study the epigenetic effects induced by themicroenvironment of human embryonic stem cells
-
Postovit LM, Seftor EA, Seftor RE, Hendrix MJ. A threedimensionalmodel to study the epigenetic effects induced by themicroenvironment of human embryonic stem cells. Stem Cells2006; 24(3): 501-5.
-
(2006)
Stem Cells
, vol.24
, Issue.3
, pp. 501-505
-
-
Postovit, L.M.1
Seftor, E.A.2
Seftor, R.E.3
Hendrix, M.J.4
-
117
-
-
33644864757
-
Reprogrammingmetastatic melanoma cells to assume a neural crest cell-likephenotype in an embryonic microenvironment
-
Kulesa PM, Kasemeier-Kulesa JC, Teddy JM, et al. Reprogrammingmetastatic melanoma cells to assume a neural crest cell-likephenotype in an embryonic microenvironment. Proc Natl Acad SciUSA 2006; 103(10): 3752-7.
-
(2006)
Proc Natl Acad SciUSA
, vol.103
, Issue.10
, pp. 3752-3757
-
-
Kulesa, P.M.1
Kasemeier-Kulesa, J.C.2
Teddy, J.M.3
-
118
-
-
69949134052
-
Nodal as a biomarkerfor melanoma progression and a new therapeutic target for clinicalintervention
-
Strizzi L, Postovit LM, Margaryan NV, et al. Nodal as a biomarkerfor melanoma progression and a new therapeutic target for clinicalintervention. Expert Rev Dermatol 2009; 4(1): 67-78.
-
(2009)
Expert Rev Dermatol
, vol.4
, Issue.1
, pp. 67-78
-
-
Strizzi, L.1
Postovit, L.M.2
Margaryan, N.V.3
-
119
-
-
85047693731
-
Antibody blockade of theCripto CFC domain suppresses tumor cell growth in vivo
-
Adkins HB, Bianco C, Schiffer SG, et al. Antibody blockade of theCripto CFC domain suppresses tumor cell growth in vivo. J ClinInvest 2003; 112(4): 575-87.
-
(2003)
J ClinInvest
, vol.112
, Issue.4
, pp. 575-587
-
-
Adkins, H.B.1
Bianco, C.2
Schiffer, S.G.3
-
120
-
-
79955837342
-
Expression of nodal and nodal receptors in prostatestem cells and prostate cancer cells: Autocrine effects on cellproliferation and migration
-
Vo BT, Khan SA. Expression of nodal and nodal receptors in prostatestem cells and prostate cancer cells: autocrine effects on cellproliferation and migration. Prostate 2011; 71(10): 1084-96.
-
(2011)
Prostate
, vol.71
, Issue.10
, pp. 1084-1096
-
-
Vo, B.T.1
Khan, S.A.2
-
121
-
-
71149083121
-
Expression of nodalsignalling components in cycling human endometrium and in endometrialcancer
-
Papageorgiou I, Nicholls PK, Wang F, et al. Expression of nodalsignalling components in cycling human endometrium and in endometrialcancer. Reprod Biol Endocrinol 2009; 7: 122.
-
(2009)
Reprod Biol Endocrinol
, vol.7
, pp. 122
-
-
Papageorgiou, I.1
Nicholls, P.K.2
Wang, F.3
-
122
-
-
8744286786
-
Nodalinduces apoptosis and inhibits proliferation in human epithelialovarian cancer cells via activin receptor-like kinase 7
-
Xu G, Zhong Y, Munir S, Yang BB, Tsang BK, Peng C. Nodalinduces apoptosis and inhibits proliferation in human epithelialovarian cancer cells via activin receptor-like kinase 7. J Clin EndocrinolMetab 2004; 89(11): 5523-34.
-
(2004)
J Clin EndocrinolMetab
, vol.89
, Issue.11
, pp. 5523-5534
-
-
Xu, G.1
Zhong, Y.2
Munir, S.3
Yang, B.B.4
Tsang, B.K.5
Peng, C.6
-
123
-
-
3843110160
-
Nodal and ALK7inhibit proliferation and induce apoptosis in human trophoblastcells
-
Munir S, Xu G, Wu Y, Yang B, Lala PK, Peng C. Nodal and ALK7inhibit proliferation and induce apoptosis in human trophoblastcells. J Biol Chem 2004; 279(30): 31277-86.
-
(2004)
J Biol Chem
, vol.279
, Issue.30
, pp. 31277-31286
-
-
Munir, S.1
Xu, G.2
Wu, Y.3
Yang, B.4
Lala, P.K.5
Peng, C.6
-
124
-
-
0026652656
-
TGF-beta family factors in Drosophila morphogenesis
-
Hoffmann FM. TGF-beta family factors in Drosophila morphogenesis. Mol Reprod Dev 1992; 32(2): 173-8.
-
(1992)
Mol Reprod Dev
, vol.32
, Issue.2
, pp. 173-178
-
-
Hoffmann, F.M.1
-
125
-
-
70349833632
-
Complex and context dependentregulation of hematopoiesis by TGF-beta superfamily signaling
-
Soderberg SS, Karlsson G, Karlsson S. Complex and context dependentregulation of hematopoiesis by TGF-beta superfamily signaling. Ann N Y Acad Sci 2009; 1176: 55-69.
-
(2009)
Ann N Y Acad Sci
, vol.1176
, pp. 55-69
-
-
Soderberg, S.S.1
Karlsson, G.2
Karlsson, S.3
-
126
-
-
66349135076
-
The TGF-beta paradox in human cancer:An update
-
Tian M, Schiemann WP. The TGF-beta paradox in human cancer:an update. Future Oncol 2009; 5(2): 259-71.
-
(2009)
Future Oncol
, vol.5
, Issue.2
, pp. 259-271
-
-
Tian, M.1
Schiemann, W.P.2
-
127
-
-
13144281709
-
Duel nature of T.G. F-beta signaling: Tumorsuppressor vs. tumor promoter
-
Bachman KE, Park BH. Duel nature of TGF-beta signaling: tumorsuppressor vs. tumor promoter. Curr Opin Oncol 2005; 17(1): 49-54.
-
(2005)
Curr Opin Oncol
, vol.17
, Issue.1
, pp. 49-54
-
-
Bachman, K.E.1
Park, B.H.2
-
128
-
-
0034677494
-
Interaction between Wntand TGF-beta signalling pathways during formation of Spemann'sorganizer
-
Nishita M, Hashimoto MK, Ogata S, et al. Interaction between Wntand TGF-beta signalling pathways during formation of Spemann'sorganizer. Nature 2000; 403(6771): 781-5.
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 781-785
-
-
Nishita, M.1
Hashimoto, M.K.2
Ogata, S.3
-
129
-
-
0029932564
-
Left-right asymmetric expressionof the TGF beta-family member lefty in mouse embryos
-
Meno C, Saijoh Y, Fujii H, et al. Left-right asymmetric expressionof the TGF beta-family member lefty in mouse embryos. Nature1996; 381(6578): 151-5.
-
(1996)
Nature
, vol.381
, Issue.6578
, pp. 151-155
-
-
Meno, C.1
Saijoh, Y.2
Fujii, H.3
-
130
-
-
1642382833
-
Notch signaling: Control of cell communication and cellfate
-
Lai EC. Notch signaling: control of cell communication and cellfate. Development 2004; 131(5): 965-73.
-
(2004)
Development
, vol.131
, Issue.5
, pp. 965-973
-
-
Lai, E.C.1
-
131
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 2006; 7(9): 678-89.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.9
, pp. 678-689
-
-
Bray, S.J.1
-
132
-
-
33846968807
-
DSL ligand endocytosis physically dissociates Notch1 heterodimersbefore activating proteolysis can occur
-
Nichols JT, Miyamoto A, Olsen SL, D'Souza B, Yao C, WeinmasterG. DSL ligand endocytosis physically dissociates Notch1 heterodimersbefore activating proteolysis can occur. J Cell Biol 2007;176(4): 445-58.
-
(2007)
J Cell Biol
, vol.176
, Issue.4
, pp. 445-458
-
-
Nichols, J.T.1
Miyamoto, A.2
Olsen, S.L.3
D'Souza, B.4
Yao, C.5
Weinmaster, G.6
-
133
-
-
0036727125
-
Gamma-secretase-mediated proteolysis in cell-surfacereceptorsignalling
-
Fortini ME. Gamma-secretase-mediated proteolysis in cell-surfacereceptorsignalling. Nat Rev Mol Cell Biol 2002; 3(9): 673-84.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.9
, pp. 673-684
-
-
Fortini, M.E.1
-
134
-
-
0034671686
-
Notch signaling: From the outside in
-
Mumm JS, Kopan R. Notch signaling: from the outside in. DevBiol 2000; 228(2): 151-65.
-
(2000)
DevBiol
, vol.228
, Issue.2
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
135
-
-
33644749306
-
Structural basis forcooperativity in recruitment of MAML coactivators to Notch transcriptioncomplexes
-
Nam Y, Sliz P, Song L, Aster JC, Blacklow SC. Structural basis forcooperativity in recruitment of MAML coactivators to Notch transcriptioncomplexes. Cell 2006; 124(5): 973-83.
-
(2006)
Cell
, vol.124
, Issue.5
, pp. 973-983
-
-
Nam, Y.1
Sliz, P.2
Song, L.3
Aster, J.C.4
Blacklow, S.C.5
-
136
-
-
33644752839
-
Notch signaling
-
Miele L. Notch signaling. Clin Cancer Res 2006; 12(4): 1074-9.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.4
, pp. 1074-1079
-
-
Miele, L.1
-
137
-
-
0037363922
-
HES and HERP families: Multipleeffectors of the Notch signaling pathway
-
Iso T, Kedes L, Hamamori Y. HES and HERP families: multipleeffectors of the Notch signaling pathway. J Cell Physiol 2003;194(3): 237-55.
-
(2003)
J Cell Physiol
, vol.194
, Issue.3
, pp. 237-255
-
-
Iso, T.1
Kedes, L.2
Hamamori, Y.3
-
138
-
-
0029930494
-
Neurogenic genes and vertebrate neurogenesis
-
Lewis J. Neurogenic genes and vertebrate neurogenesis. Curr OpinNeurobiol 1996; 6(1): 3-10.
-
(1996)
Curr OpinNeurobiol
, vol.6
, Issue.1
, pp. 3-10
-
-
Lewis, J.1
-
139
-
-
0032242705
-
Notch signalling and the control of cell fate choices invertebrates
-
Lewis J. Notch signalling and the control of cell fate choices invertebrates. Semin Cell Dev Biol 1998; 9(6): 583-9.
-
(1998)
Semin Cell Dev Biol
, vol.9
, Issue.6
, pp. 583-589
-
-
Lewis, J.1
-
140
-
-
0029061491
-
Primaryneurogenesis in Xenopus embryos regulated by a homologueof the Drosophila neurogenic gene Delta
-
Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C. Primaryneurogenesis in Xenopus embryos regulated by a homologueof the Drosophila neurogenic gene Delta. Nature 1995; 375(6534):761-6.
-
(1995)
Nature
, vol.375
, Issue.6534
, pp. 761-766
-
-
Chitnis, A.1
Henrique, D.2
Lewis, J.3
Ish-Horowicz, D.4
Kintner, C.5
-
141
-
-
0031240003
-
Maintenance of neuroepithelialprogenitor cells by Delta-Notch signalling in the embryonicchick retina
-
Henrique D, Hirsinger E, Adam J, et al. Maintenance of neuroepithelialprogenitor cells by Delta-Notch signalling in the embryonicchick retina. Curr Biol 1997; 7(9): 661-70.
-
(1997)
Curr Biol
, vol.7
, Issue.9
, pp. 661-670
-
-
Henrique, D.1
Hirsinger, E.2
Adam, J.3
-
142
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene ortumour suppressor?
-
Radtke F, Raj K. The role of Notch in tumorigenesis: oncogene ortumour suppressor? Nat Rev Cancer 2003; 3(10): 756-67.
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.10
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
143
-
-
0031451172
-
The LIN-12/Notch signaling pathway and itsregulation
-
Kimble J, Simpson P. The LIN-12/Notch signaling pathway and itsregulation. Annu Rev Cell Dev Biol 1997; 13: 333-61.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 333-361
-
-
Kimble, J.1
Simpson, P.2
-
145
-
-
0037382518
-
Notch signaling in lymphopoiesis
-
Pear WS, Radtke F. Notch signaling in lymphopoiesis. Semin Immunol2003; 15(2): 69-79.
-
(2003)
Semin Immunol
, vol.15
, Issue.2
, pp. 69-79
-
-
Pear, W.S.1
Radtke, F.2
-
146
-
-
0029850324
-
Inhibition of granulocytic differentiation by mNotch1
-
Milner LA, Bigas A, Kopan R, Brashem-Stein C, Bernstein ID, Martin DI. Inhibition of granulocytic differentiation by mNotch1. Proc Natl Acad Sci USA 1996; 93(23): 13014-9.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.23
, pp. 13014-13019
-
-
Milner, L.A.1
Bigas, A.2
Kopan, R.3
Brashem-Stein, C.4
Bernstein, I.D.5
Martin, D.I.6
-
147
-
-
0033561454
-
Notch as a mediator of cell fate determinationin hematopoiesis: Evidence and speculation
-
Milner LA, Bigas A. Notch as a mediator of cell fate determinationin hematopoiesis: evidence and speculation. Blood 1999; 93(8):2431-48.
-
(1999)
Blood
, vol.93
, Issue.8
, pp. 2431-2448
-
-
Milner, L.A.1
Bigas, A.2
-
148
-
-
0035895087
-
A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice byretroviral-mediated gene transfer
-
Yan XQ, Sarmiento U, Sun Y, et al. A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice byretroviral-mediated gene transfer. Blood 2001; 98(13): 3793-9.
-
(2001)
Blood
, vol.98
, Issue.13
, pp. 3793-3799
-
-
Yan, X.Q.1
Sarmiento, U.2
Sun, Y.3
-
149
-
-
0029808295
-
Frequent provirus insertionalmutagenesis of Notch1 in thymomas of MMTVD/myc transgenicmice suggests a collaboration of c-myc and Notch1 for oncogenesis
-
Girard L, Hanna Z, Beaulieu N, et al. Frequent provirus insertionalmutagenesis of Notch1 in thymomas of MMTVD/myc transgenicmice suggests a collaboration of c-myc and Notch1 for oncogenesis. Genes Dev 1996; 10(15): 1930-44.
-
(1996)
Genes Dev
, vol.10
, Issue.15
, pp. 1930-1944
-
-
Girard, L.1
Hanna, Z.2
Beaulieu, N.3
-
150
-
-
0029819876
-
Transductionof Notch2 in feline leukemia virus-induced thymic lymphoma
-
Rohn JL, Lauring AS, Linenberger ML, Overbaugh J. Transductionof Notch2 in feline leukemia virus-induced thymic lymphoma. JVirol 1996; 70(11): 8071-80.
-
(1996)
JVirol
, vol.70
, Issue.11
, pp. 8071-8080
-
-
Rohn, J.L.1
Lauring, A.S.2
Linenberger, M.L.3
Overbaugh, J.4
-
151
-
-
0037218811
-
Growth suppression of pre-Tacute lymphoblastic leukemia cells by inhibition of notch signaling
-
Weng AP, Nam Y, Wolfe MS, et al. Growth suppression of pre-Tacute lymphoblastic leukemia cells by inhibition of notch signaling. Mol Cell Biol 2003; 23(2): 655-64.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.2
, pp. 655-664
-
-
Weng, A.P.1
Nam, Y.2
Wolfe, M.S.3
-
152
-
-
0036734148
-
Activation of Notch-1 signalingmaintains the neoplastic phenotype in human Ras-transformedcells
-
Weijzen S, Rizzo P, Braid M, et al. Activation of Notch-1 signalingmaintains the neoplastic phenotype in human Ras-transformedcells. Nat Med 2002; 8(9): 979-86.
-
(2002)
Nat Med
, vol.8
, Issue.9
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
-
153
-
-
24944506696
-
High-level coexpression ofJAG1 and NOTCH1 is observed in human breast cancer and is associatedwith poor overall survival
-
Reedijk M, Odorcic S, Chang L, et al. High-level coexpression ofJAG1 and NOTCH1 is observed in human breast cancer and is associatedwith poor overall survival. Cancer Res 2005; 65(18):8530-7.
-
(2005)
Cancer Res
, vol.65
, Issue.18
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
-
154
-
-
4944241544
-
JAGGED1 expression isassociated with prostate cancer metastasis and recurrence
-
Santagata S, Demichelis F, Riva A, et al. JAGGED1 expression isassociated with prostate cancer metastasis and recurrence. CancerRes 2004; 64(19): 6854-7.
-
(2004)
CancerRes
, vol.64
, Issue.19
, pp. 6854-6857
-
-
Santagata, S.1
Demichelis, F.2
Riva, A.3
-
155
-
-
33646421636
-
Defining aggressive prostatecancer using a 12-gene model
-
Bismar TA, Demichelis F, Riva A, et al. Defining aggressive prostatecancer using a 12-gene model. Neoplasia 2006; 8(1): 59-68.
-
(2006)
Neoplasia
, vol.8
, Issue.1
, pp. 59-68
-
-
Bismar, T.A.1
Demichelis, F.2
Riva, A.3
-
156
-
-
32944470488
-
Aberrant activation of notchsignaling in human breast cancer
-
Stylianou S, Clarke RB, Brennan K. Aberrant activation of notchsignaling in human breast cancer. Cancer Res 2006; 66(3): 1517-25.
-
(2006)
Cancer Res
, vol.66
, Issue.3
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
157
-
-
27644490306
-
Activation of Notch1 signalingis required for beta-catenin-mediated human primary melanomaprogression
-
Balint K, Xiao M, Pinnix CC, et al. Activation of Notch1 signalingis required for beta-catenin-mediated human primary melanomaprogression. J Clin Invest 2005; 115(11): 3166-76.
-
(2005)
J Clin Invest
, vol.115
, Issue.11
, pp. 3166-3176
-
-
Balint, K.1
Xiao, M.2
Pinnix, C.C.3
-
158
-
-
3442894137
-
Expression profiling revealsnovel pathways in the transformation of melanocytes tomelanomas
-
Hoek K, Rimm DL, Williams KR, et al. Expression profiling revealsnovel pathways in the transformation of melanocytes tomelanomas. Cancer Res 2004; 64(15): 5270-82.
-
(2004)
Cancer Res
, vol.64
, Issue.15
, pp. 5270-5282
-
-
Hoek, K.1
Rimm, D.L.2
Williams, K.R.3
-
159
-
-
33646257783
-
Notch1 signaling promotes primarymelanoma progression by activating mitogen-activated proteinkinase/phosphatidylinositol 3-kinase-Akt pathways and upregulatingN-cadherin expression
-
Liu ZJ, Xiao M, Balint K, et al. Notch1 signaling promotes primarymelanoma progression by activating mitogen-activated proteinkinase/phosphatidylinositol 3-kinase-Akt pathways and upregulatingN-cadherin expression. Cancer Res 2006; 66(8): 4182-90.
-
(2006)
Cancer Res
, vol.66
, Issue.8
, pp. 4182-4190
-
-
Liu, Z.J.1
Xiao, M.2
Balint, K.3
-
160
-
-
34548833559
-
Notch2 signaling induces apoptosisand inhibits human MDA-MB-231 xenograft growth
-
O'Neill CF, Urs S, Cinelli C, et al. Notch2 signaling induces apoptosisand inhibits human MDA-MB-231 xenograft growth. Am JPathol 2007; 171(3): 1023-36.
-
(2007)
Am JPathol
, vol.171
, Issue.3
, pp. 1023-1036
-
-
O'Neill, C.F.1
Urs, S.2
Cinelli, C.3
-
161
-
-
17844384528
-
Notch signaling is adirect determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A, Talora C, Okuyama R, et al. Notch signaling is adirect determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 2001; 20(13): 3427-36.
-
(2001)
EMBO J
, vol.20
, Issue.13
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
-
162
-
-
0024535228
-
The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastomagene product
-
Dyson N, Howley PM, Munger K, Harlow E. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastomagene product. Science 1989; 243(4893): 934-7.
-
(1989)
Science
, vol.243
, Issue.4893
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Munger, K.3
Harlow, E.4
-
163
-
-
0035956258
-
Biological activities andmolecular targets of the human papillomavirus E7 oncoprotein
-
Munger K, Basile JR, Duensing S, et al. Biological activities andmolecular targets of the human papillomavirus E7 oncoprotein. Oncogene 2001; 20(54): 7888-98.
-
(2001)
Oncogene
, vol.20
, Issue.54
, pp. 7888-7898
-
-
Munger, K.1
Basile, J.R.2
Duensing, S.3
-
164
-
-
0036784599
-
Inactivation of both the retinoblastomatumor suppressor and p21 by the human papillomavirustype 16 E7 oncoprotein is necessary to inhibit cell cycle arrest inhuman epithelial cells
-
Helt AM, Funk JO, Galloway DA. Inactivation of both the retinoblastomatumor suppressor and p21 by the human papillomavirustype 16 E7 oncoprotein is necessary to inhibit cell cycle arrest inhuman epithelial cells. J Virol 2002; 76(20): 10559-68.
-
(2002)
J Virol
, vol.76
, Issue.20
, pp. 10559-10568
-
-
Helt, A.M.1
Funk, J.O.2
Galloway, D.A.3
-
165
-
-
0036787917
-
E7 abolishesraf-induced arrest via mislocalization of p21(Cip1)
-
Westbrook TF, Nguyen DX, Thrash BR, McCance DJ. E7 abolishesraf-induced arrest via mislocalization of p21(Cip1). Mol CellBiol 2002; 22(20): 7041-52.
-
(2002)
Mol CellBiol
, vol.22
, Issue.20
, pp. 7041-7052
-
-
Westbrook, T.F.1
Nguyen, D.X.2
Thrash, B.R.3
McCance, D.J.4
-
166
-
-
34447641262
-
Theemerging role of Wnt signaling in the pathogenesis of acute myeloidleukemia
-
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C. Theemerging role of Wnt signaling in the pathogenesis of acute myeloidleukemia. Leukemia 2007; 21(8): 1638-47.
-
(2007)
Leukemia
, vol.21
, Issue.8
, pp. 1638-1647
-
-
Mikesch, J.H.1
Steffen, B.2
Berdel, W.E.3
Serve, H.4
Muller-Tidow, C.5
-
167
-
-
0038783316
-
Secreted antagonists of the Wnt signallingpathway
-
Kawano Y, Kypta R. Secreted antagonists of the Wnt signallingpathway. J Cell Sci 2003; 116(Pt 13): 2627-34.
-
(2003)
J Cell Sci
, vol.116
, Issue.PART. 13
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
168
-
-
53349091628
-
Defining earlylineage specification of human embryonic stem cells by the orchestratedbalance of canonical Wnt/beta-catenin, Activin/Nodal andBMP signaling
-
Sumi T, Tsuneyoshi N, Nakatsuji N, Suemori H. Defining earlylineage specification of human embryonic stem cells by the orchestratedbalance of canonical Wnt/beta-catenin, Activin/Nodal andBMP signaling. Development 2008; 135(17): 2969-79.
-
(2008)
Development
, vol.135
, Issue.17
, pp. 2969-2979
-
-
Sumi, T.1
Tsuneyoshi, N.2
Nakatsuji, N.3
Suemori, H.4
-
169
-
-
34247226529
-
Gene function in mouse embryogenesis: Getset for gastrulation
-
Tam PP, Loebel DA. Gene function in mouse embryogenesis: getset for gastrulation. Nat Rev Genet 2007; 8(5): 368-81.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.5
, pp. 368-381
-
-
Tam, P.P.1
Loebel, D.A.2
-
170
-
-
4344584730
-
WNT and betacateninsignalling: Diseases and therapies
-
Moon RT, Kohn AD, De Ferrari GV, Kaykas A. WNT and betacateninsignalling: diseases and therapies. Nat Rev Genet 2004;5(9): 691-701.
-
(2004)
Nat Rev Genet
, vol.5
, Issue.9
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
de Ferrari, G.V.3
Kaykas, A.4
-
171
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stemcells through activation of Wnt signaling by a pharmacologicalGSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stemcells through activation of Wnt signaling by a pharmacologicalGSK-3-specific inhibitor. Nat Med 2004; 10(1): 55-63.
-
(2004)
Nat Med
, vol.10
, Issue.1
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
172
-
-
1942537708
-
The significance of theWnt pathway in the pathology of human cancers
-
Karim R, Tse G, Putti T, Scolyer R, Lee S. The significance of theWnt pathway in the pathology of human cancers. Pathology 2004;36(2): 120-8.
-
(2004)
Pathology
, vol.36
, Issue.2
, pp. 120-128
-
-
Karim, R.1
Tse, G.2
Putti, T.3
Scolyer, R.4
Lee, S.5
-
173
-
-
0032483439
-
Identification of c-MYC as atarget of the APC pathway
-
He TC, Sparks AB, Rago C, et al. Identification of c-MYC as atarget of the APC pathway. Science 1998; 281(5382): 1509-12.
-
(1998)
Science
, vol.281
, Issue.5382
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
-
174
-
-
0032492954
-
Downregulationof beta-catenin by human Axin and its association with theAPC tumor suppressor, beta-catenin and GSK3 beta
-
Hart MJ, de los SR, Albert IN, Rubinfeld B, Polakis P. Downregulationof beta-catenin by human Axin and its association with theAPC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol1998; 8(10): 573-81.
-
(1998)
Curr Biol
, vol.8
, Issue.10
, pp. 573-581
-
-
Hart, M.J.1
de Los, S.R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
175
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms acomplex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
-
Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway, forms acomplex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J 1998;17(5): 1371-84.
-
(1998)
EMBO J
, vol.17
, Issue.5
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
176
-
-
33846172711
-
Expression of the Wntinhibitor Dickkopf-1 is required for the induction of neural markersin mouse embryonic stem cells differentiating in response to retinoicacid
-
Verani R, Cappuccio I, Spinsanti P, et al. Expression of the Wntinhibitor Dickkopf-1 is required for the induction of neural markersin mouse embryonic stem cells differentiating in response to retinoicacid. J Neurochem 2007; 100(1): 242-50.
-
(2007)
J Neurochem
, vol.100
, Issue.1
, pp. 242-250
-
-
Verani, R.1
Cappuccio, I.2
Spinsanti, P.3
-
177
-
-
0034329498
-
Different activities of the frizzled-related proteins frzb2 and sizzled2during Xenopus anteroposterior patterning
-
Bradley L, Sun B, Collins-Racie L, LaVallie E, McCoy J, Sive H. Different activities of the frizzled-related proteins frzb2 and sizzled2during Xenopus anteroposterior patterning. Dev Biol 2000;227(1): 118-32.
-
(2000)
Dev Biol
, vol.227
, Issue.1
, pp. 118-132
-
-
Bradley, L.1
Sun, B.2
Collins-Racie, L.3
la Vallie, E.4
McCoy, J.5
Sive, H.6
-
178
-
-
0038275800
-
Regulation of the Wnt signaling pathway by disabled-2(Dab2)
-
Hocevar BA, Mou F, Rennolds JL, Morris SM, Cooper JA, HowePH. Regulation of the Wnt signaling pathway by disabled-2(Dab2). EMBO J 2003; 22(12): 3084-94.
-
(2003)
EMBO J
, vol.22
, Issue.12
, pp. 3084-3094
-
-
Hocevar, B.A.1
Mou, F.2
Rennolds, J.L.3
Morris, S.M.4
Cooper, J.A.5
Howe, P.H.6
-
179
-
-
0036225314
-
Dapper, a Dishevelledassociatedantagonist of beta-catenin and JNK signaling, is requiredfor notochord formation
-
Cheyette BN, Waxman JS, Miller JR, et al. Dapper, a Dishevelledassociatedantagonist of beta-catenin and JNK signaling, is requiredfor notochord formation. Dev Cell 2002; 2(4): 449-61.
-
(2002)
Dev Cell
, vol.2
, Issue.4
, pp. 449-461
-
-
Cheyette, B.N.1
Waxman, J.S.2
Miller, J.R.3
-
180
-
-
0033486152
-
beta-catenin signaling and cancer
-
Morin PJ. beta-catenin signaling and cancer. Bioessays 1999;21(12): 1021-30.
-
(1999)
Bioessays
, vol.21
, Issue.12
, pp. 1021-1030
-
-
Morin, P.J.1
-
181
-
-
0242515751
-
Chibby, a nuclear beta-catenin-associated antagonist of theWnt/Wingless pathway
-
Takemaru K, Yamaguchi S, Lee YS, Zhang Y, Carthew RW, MoonRT. Chibby, a nuclear beta-catenin-associated antagonist of theWnt/Wingless pathway. Nature 2003; 422(6934): 905-9.
-
(2003)
Nature
, vol.422
, Issue.6934
, pp. 905-909
-
-
Takemaru, K.1
Yamaguchi, S.2
Lee, Y.S.3
Zhang, Y.4
Carthew, R.W.5
Moon, R.T.6
-
182
-
-
0028971954
-
Lack of beta-catenin affects mouse development at gastrulation
-
Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, KemlerR. Lack of beta-catenin affects mouse development at gastrulation. Development 1995; 121(11): 3529-37.
-
(1995)
Development
, vol.121
, Issue.11
, pp. 3529-3537
-
-
Haegel, H.1
Larue, L.2
Ohsugi, M.3
Fedorov, L.4
Herrenknecht, K.5
Kemler, R.6
-
183
-
-
0030989287
-
A role forthe Wnt gene family in hematopoiesis: Expansion of multilineageprogenitor cells
-
Austin TW, Solar GP, Ziegler FC, Liem L, Matthews W. A role forthe Wnt gene family in hematopoiesis: expansion of multilineageprogenitor cells. Blood 1997; 89(10): 3624-35.
-
(1997)
Blood
, vol.89
, Issue.10
, pp. 3624-3635
-
-
Austin, T.W.1
Solar, G.P.2
Ziegler, F.C.3
Liem, L.4
Matthews, W.5
-
184
-
-
0034672241
-
WNT signaling modulatesthe diversification of hematopoietic cells
-
Brandon C, Eisenberg LM, Eisenberg CA. WNT signaling modulatesthe diversification of hematopoietic cells. Blood 2000; 96(13):4132-41.
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4132-4141
-
-
Brandon, C.1
Eisenberg, L.M.2
Eisenberg, C.A.3
-
185
-
-
0037737728
-
A role for Wnt signalling inself-renewal of haematopoietic stem cells
-
Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling inself-renewal of haematopoietic stem cells. Nature 2003; 423(6938):409-14.
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
-
186
-
-
79951832932
-
GSK-3beta inhibition promotesengraftment of ex vivo-expanded hematopoietic stem cellsand modulates gene expression
-
Ko KH, Holmes T, Palladinetti P, et al. GSK-3beta inhibition promotesengraftment of ex vivo-expanded hematopoietic stem cellsand modulates gene expression. Stem Cells 2011; 29(1): 108-18.
-
(2011)
Stem Cells
, vol.29
, Issue.1
, pp. 108-118
-
-
Ko, K.H.1
Holmes, T.2
Palladinetti, P.3
-
187
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127(3): 469-80.
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 469-480
-
-
Clevers, H.1
-
188
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature2005; 434(7035): 843-50.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
189
-
-
0031848068
-
Depletion of epithelial stemcellcompartments in the small intestine of mice lacking Tcf-4
-
Korinek V, Barker N, Moerer P, et al. Depletion of epithelial stemcellcompartments in the small intestine of mice lacking Tcf-4. NatGenet 1998; 19(4): 379-83.
-
(1998)
NatGenet
, vol.19
, Issue.4
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
-
190
-
-
23844455584
-
Mitogenic influence of humanR-spondin1 on the intestinal epithelium
-
Kim KA, Kakitani M, Zhao J, et al. Mitogenic influence of humanR-spondin1 on the intestinal epithelium. Science 2005; 309(5738):1256-9.
-
(2005)
Science
, vol.309
, Issue.5738
, pp. 1256-1259
-
-
Kim, K.A.1
Kakitani, M.2
Zhao, J.3
-
191
-
-
22344441322
-
Defining the impact of beta-catenin/Tcf transactivation on epithelialstem cells
-
Lowry WE, Blanpain C, Nowak JA, Guasch G, Lewis L, Fuchs E. Defining the impact of beta-catenin/Tcf transactivation on epithelialstem cells. Genes Dev 2005; 19(13): 1596-611.
-
(2005)
Genes Dev
, vol.19
, Issue.13
, pp. 1596-1611
-
-
Lowry, W.E.1
Blanpain, C.2
Nowak, J.A.3
Guasch, G.4
Lewis, L.5
Fuchs, E.6
-
192
-
-
84860302370
-
New Insights into Epithelial-Mesenchymal Transition inKidney Fibrosis
-
Liu Y. New Insights into Epithelial-Mesenchymal Transition inKidney Fibrosis. J Am Soc Nephrol 2009.
-
(2009)
J Am Soc Nephrol
-
-
Liu, Y.1
-
193
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14(15):1837-51.
-
(2000)
Genes Dev
, vol.14
, Issue.15
, pp. 1837-1851
-
-
Polakis, P.1
-
194
-
-
74549225756
-
Active Wnt signalling is associated with low differentiationand high proliferation in human biliary tract cancer in vitro and invivo and is sensitive to pharmacological inhibition
-
Kiesslich T, Alinger B, Wolkersdorfer GW, Ocker M, Neureiter D, Berr F. Active Wnt signalling is associated with low differentiationand high proliferation in human biliary tract cancer in vitro and invivo and is sensitive to pharmacological inhibition. Int J Oncol2010; 36(1): 49-58.
-
(2010)
Int J Oncol
, vol.36
, Issue.1
, pp. 49-58
-
-
Kiesslich, T.1
Alinger, B.2
Wolkersdorfer, G.W.3
Ocker, M.4
Neureiter, D.5
Berr, F.6
-
195
-
-
35448976966
-
Role of Wnt/beta-catenin signalingpathway in epithelial-mesenchymal transition of human prostatecancer induced by hypoxia-inducible factor-1alpha
-
Jiang YG, Luo Y, He DL, et al. Role of Wnt/beta-catenin signalingpathway in epithelial-mesenchymal transition of human prostatecancer induced by hypoxia-inducible factor-1alpha. Int J Urol2007; 14(11): 1034-9.
-
(2007)
Int J Urol
, vol.14
, Issue.11
, pp. 1034-1039
-
-
Jiang, Y.G.1
Luo, Y.2
He, D.L.3
-
196
-
-
0030592517
-
Lessons from hereditary colorectalcancer
-
Kinzler KW, Vogelstein B. Lessons from hereditary colorectalcancer. Cell 1996; 87(2): 159-70.
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
197
-
-
0030975671
-
Constitutive transcriptionalactivation by a beta-catenin-Tcf complex in APC-/-colon carcinoma
-
Korinek V, Barker N, Morin PJ, et al. Constitutive transcriptionalactivation by a beta-catenin-Tcf complex in APC-/-colon carcinoma. Science 1997; 275(5307): 1784-7.
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
-
198
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin PJ, Sparks AB, Korinek V, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275(5307): 1787-90.
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
199
-
-
0033780630
-
Mutations in AXIN2 cause colorectalcancer with defective mismatch repair by activating betacatenin/TCF signalling
-
Liu W, Dong X, Mai M, et al. Mutations in AXIN2 cause colorectalcancer with defective mismatch repair by activating betacatenin/TCF signalling. Nat Genet 2000; 26(2): 146-7.
-
(2000)
Nat Genet
, vol.26
, Issue.2
, pp. 146-147
-
-
Liu, W.1
Dong, X.2
Mai, M.3
-
200
-
-
33645728839
-
Human sebaceous tumors harbor inactivating mutations in LEF1
-
Takeda H, Lyle S, Lazar AJ, Zouboulis CC, Smyth I, Watt FM. Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med 2006; 12(4): 395-7.
-
(2006)
Nat Med
, vol.12
, Issue.4
, pp. 395-397
-
-
Takeda, H.1
Lyle, S.2
Lazar, A.J.3
Zouboulis, C.C.4
Smyth, I.5
Watt, F.M.6
-
201
-
-
0034696336
-
Use of MMTV-Wnt-1 transgenicmice for studying the genetic basis of breast cancer
-
Li Y, Hively WP, Varmus HE. Use of MMTV-Wnt-1 transgenicmice for studying the genetic basis of breast cancer. Oncogene2000; 19(8): 1002-9.
-
(2000)
Oncogene
, vol.19
, Issue.8
, pp. 1002-1009
-
-
Li, Y.1
Hively, W.P.2
Varmus, H.E.3
-
202
-
-
9144269759
-
Evidence that transgenesencoding components of the Wnt signaling pathway preferentiallyinduce mammary cancers from progenitor cells
-
Li Y, Welm B, Podsypanina K, et al. Evidence that transgenesencoding components of the Wnt signaling pathway preferentiallyinduce mammary cancers from progenitor cells. Proc Natl Acad SciUSA 2003; 100(26): 15853-8.
-
(2003)
Proc Natl Acad SciUSA
, vol.100
, Issue.26
, pp. 15853-15858
-
-
Li, Y.1
Welm, B.2
Podsypanina, K.3
-
203
-
-
1642570244
-
The transformingactivity of Wnt effectors correlates with their ability to inducethe accumulation of mammary progenitor cells
-
Liu BY, McDermott SP, Khwaja SS, Alexander CM. The transformingactivity of Wnt effectors correlates with their ability to inducethe accumulation of mammary progenitor cells. Proc NatlAcad Sci USA 2004; 101(12): 4158-63.
-
(2004)
Proc NatlAcad Sci USA
, vol.101
, Issue.12
, pp. 4158-4163
-
-
Liu, B.Y.1
McDermott, S.P.2
Khwaja, S.S.3
Alexander, C.M.4
-
204
-
-
33846465548
-
Baf60c is a nuclearNotch signaling component required for the establishment of leftrightasymmetry
-
Takeuchi JK, Lickert H, Bisgrove BW, et al. Baf60c is a nuclearNotch signaling component required for the establishment of leftrightasymmetry. Proc Natl Acad Sci USA 2007; 104(3): 846-51.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.3
, pp. 846-851
-
-
Takeuchi, J.K.1
Lickert, H.2
Bisgrove, B.W.3
-
205
-
-
75549087039
-
Enhancement of Notchreceptor maturation and signaling sensitivity by Cripto-1
-
Watanabe K, Nagaoka T, Lee JM, et al. Enhancement of Notchreceptor maturation and signaling sensitivity by Cripto-1. J CellBiol 2009; 187(3): 343-53.
-
(2009)
J CellBiol
, vol.187
, Issue.3
, pp. 343-353
-
-
Watanabe, K.1
Nagaoka, T.2
Lee, J.M.3
-
206
-
-
0033573035
-
T(Brachyury) is a direct target of Wnt3a during paraxial mesodermspecification
-
Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP. T(Brachyury) is a direct target of Wnt3a during paraxial mesodermspecification. Genes Dev 1999; 13(24): 3185-90.
-
(1999)
Genes Dev
, vol.13
, Issue.24
, pp. 3185-3190
-
-
Yamaguchi, T.P.1
Takada, S.2
Yoshikawa, Y.3
Wu, N.4
McMahon, A.P.5
-
207
-
-
6044272725
-
Zebrafish Dpr2 inhibitsmesoderm induction by promoting degradation of nodal receptors
-
Zhang L, Zhou H, Su Y, Sun Z, et al. Zebrafish Dpr2 inhibitsmesoderm induction by promoting degradation of nodal receptors. Science 2004; 306(5693): 114-7.
-
(2004)
Science
, vol.306
, Issue.5693
, pp. 114-117
-
-
Zhang, L.1
Zhou, H.2
Su, Y.3
Sun, Z.4
-
208
-
-
0033602241
-
The head inducer Cerberus is amultifunctional antagonist of Nodal, BMP and Wnt signals
-
Piccolo S, Agius E, Leyns L, et al. The head inducer Cerberus is amultifunctional antagonist of Nodal, BMP and Wnt signals. Nature1999; 397(6721): 707-10.
-
(1999)
Nature
, vol.397
, Issue.6721
, pp. 707-710
-
-
Piccolo, S.1
Agius, E.2
Leyns, L.3
-
209
-
-
33645054573
-
Nodal signals pattern vertebrate embryos
-
Tian T, Meng AM. Nodal signals pattern vertebrate embryos. CellMol Life Sci 2006; 63(6): 672-85.
-
(2006)
CellMol Life Sci
, vol.63
, Issue.6
, pp. 672-685
-
-
Tian, T.1
Meng, A.M.2
-
210
-
-
0037164735
-
Lefty-dependent inhibition of Nodal-andWnt-responsive organizer gene expression is essential for normalgastrulation
-
Branford WW, Yost HJ. Lefty-dependent inhibition of Nodal-andWnt-responsive organizer gene expression is essential for normalgastrulation. Curr Biol 2002; 12(24): 2136-41.
-
(2002)
Curr Biol
, vol.12
, Issue.24
, pp. 2136-2141
-
-
Branford, W.W.1
Yost, H.J.2
-
211
-
-
0031196157
-
Two closely-related left-rightasymmetrically expressed genes, lefty-1 and lefty-2: Their distinctexpression domains, chromosomal linkage and direct neuralizingactivity in Xenopus embryos
-
Meno C, Ito Y, Saijoh Y, et al. Two closely-related left-rightasymmetrically expressed genes, lefty-1 and lefty-2: their distinctexpression domains, chromosomal linkage and direct neuralizingactivity in Xenopus embryos. Genes Cells 1997; 2(8): 513-24.
-
(1997)
Genes Cells
, vol.2
, Issue.8
, pp. 513-524
-
-
Meno, C.1
Ito, Y.2
Saijoh, Y.3
-
212
-
-
0041530319
-
The molecular nature of the zebrafishtail organizer
-
Agathon A, Thisse C, Thisse B. The molecular nature of the zebrafishtail organizer. Nature 2003; 424(6947): 448-52.
-
(2003)
Nature
, vol.424
, Issue.6947
, pp. 448-452
-
-
Agathon, A.1
Thisse, C.2
Thisse, B.3
-
213
-
-
0033056019
-
The oxygen trail: Tissue oxygenation
-
Nathan AT, Singer M. The oxygen trail: tissue oxygenation. BrMed Bull 1999; 55(1): 96-108.
-
(1999)
BrMed Bull
, vol.55
, Issue.1
, pp. 96-108
-
-
Nathan, A.T.1
Singer, M.2
-
214
-
-
34548426564
-
Oxygen distribution and consumption in the macaqueretina
-
Birol G, Wang S, Budzynski E, Wangsa-Wirawan ND, LinsenmeierRA. Oxygen distribution and consumption in the macaqueretina. Am J Physiol Heart Circ Physiol 2007; 293(3): H1696-H1704.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, Issue.3
-
-
Birol, G.1
Wang, S.2
Budzynski, E.3
Wangsa-Wirawan, N.D.4
Linsenmeier, R.A.5
-
215
-
-
0036320934
-
Cellular adaptation to hypoxia: O2-sensing proteinhydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
-
Wenger RH. Cellular adaptation to hypoxia: O2-sensing proteinhydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression. FASEB J 2002; 16(10): 1151-62.
-
(2002)
FASEB J
, vol.16
, Issue.10
, pp. 1151-1162
-
-
Wenger, R.H.1
-
216
-
-
0034751813
-
Mechanism, origin, and evolution ofanoxia tolerance in animals
-
Hochachka PW, Lutz PL. Mechanism, origin, and evolution ofanoxia tolerance in animals. Comp Biochem Physiol B BiochemMol Biol 2001; 130(4): 435-59.
-
(2001)
Comp Biochem Physiol B BiochemMol Biol
, vol.130
, Issue.4
, pp. 435-459
-
-
Hochachka, P.W.1
Lutz, P.L.2
-
217
-
-
0029796904
-
Unifying theory ofhypoxia tolerance: Molecular/metabolic defense and rescue mechanismsfor surviving oxygen lack
-
Hochachka PW, Buck LT, Doll CJ, Land SC. Unifying theory ofhypoxia tolerance: molecular/metabolic defense and rescue mechanismsfor surviving oxygen lack. Proc Natl Acad Sci USA 1996;93(18): 9493-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.18
, pp. 9493-9498
-
-
Hochachka, P.W.1
Buck, L.T.2
Doll, C.J.3
Land, S.C.4
-
218
-
-
0034107952
-
Mammalian oxygen sensing, signalling and generegulation
-
Wenger RH. Mammalian oxygen sensing, signalling and generegulation. J Exp Biol 2000; 203(Pt 8): 1253-63.
-
(2000)
J Exp Biol
, vol.203
, Issue.PART 8
, pp. 1253-1263
-
-
Wenger, R.H.1
-
219
-
-
70349570410
-
HIF-1alpha modulates energy metabolismin cancer cells by inducing over-expression of specificglycolytic isoforms
-
Marin-Hernandez A, Gallardo-Perez JC, Ralph SJ, Rodriguez-Enriquez S, Moreno-Sanchez R. HIF-1alpha modulates energy metabolismin cancer cells by inducing over-expression of specificglycolytic isoforms. Mini Rev Med Chem 2009; 9(9): 1084-101.
-
(2009)
Mini Rev Med Chem
, vol.9
, Issue.9
, pp. 1084-1101
-
-
Marin-Hernandez, A.1
Gallardo-Perez, J.C.2
Ralph, S.J.3
Rodriguez-Enriquez, S.4
Moreno-Sanchez, R.5
-
220
-
-
0036359548
-
Hypoxia--a key regulatory factor in tumour growth
-
Harris AL. Hypoxia--a key regulatory factor in tumour growth. NatRev Cancer 2002; 2(1): 38-47.
-
(2002)
NatRev Cancer
, vol.2
, Issue.1
, pp. 38-47
-
-
Harris, A.L.1
-
221
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer2003; 3(10): 721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.10
, pp. 721-732
-
-
Semenza, G.L.1
-
222
-
-
34547135687
-
Hypoxia and cancer
-
Semenza GL. Hypoxia and cancer. Cancer Metastasis Rev 2007;26(2): 223-4.
-
(2007)
Cancer Metastasis Rev
, vol.26
, Issue.2
, pp. 223-224
-
-
Semenza, G.L.1
-
223
-
-
0037490210
-
Hypoxia-inducible factor and its biomedicalrelevance
-
Huang LE, Bunn HF. Hypoxia-inducible factor and its biomedicalrelevance. J Biol Chem 2003; 278(22): 19575-8.
-
(2003)
J Biol Chem
, vol.278
, Issue.22
, pp. 19575-19578
-
-
Huang, L.E.1
Bunn, H.F.2
-
224
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza GL. Hypoxia-inducible factor 1 (HIF-1) pathway. SciSTKE 2007; 2007(407): cm8.
-
(2007)
SciSTKE
, vol.2007
, Issue.407
-
-
Semenza, G.L.1
-
225
-
-
35248824187
-
Oxygen sensing and hypoxia-inducedresponses
-
Coleman ML, Ratcliffe PJ. Oxygen sensing and hypoxia-inducedresponses. Essays Biochem 2007; 43: 1-15.
-
(2007)
Essays Biochem
, vol.43
, pp. 1-15
-
-
Coleman, M.L.1
Ratcliffe, P.J.2
-
226
-
-
33748849657
-
The role of the hypoxia-induciblefactor in tumor metabolism growth and invasion
-
Brahimi-Horn C, Pouyssegur J. The role of the hypoxia-induciblefactor in tumor metabolism growth and invasion. Bull Cancer 2006;93(8): E73-E80.
-
(2006)
Bull Cancer
, vol.93
, Issue.8
-
-
Brahimi-Horn, C.1
Pouyssegur, J.2
-
227
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, andcancer
-
Keith B, Simon MC. Hypoxia-inducible factors, stem cells, andcancer. Cell 2007; 129(3): 465-72.
-
(2007)
Cell
, vol.129
, Issue.3
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
228
-
-
20744445650
-
Contrasting properties ofhypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
Raval RR, Lau KW, Tran MG, et al. Contrasting properties ofhypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol 2005;25(13): 5675-86.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.13
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.3
-
229
-
-
0037315337
-
Widespreadhypoxia-inducible expression of HIF-2alpha in distinct cell populationsof different organs
-
Wiesener MS, Jurgensen JS, Rosenberger C, et al. Widespreadhypoxia-inducible expression of HIF-2alpha in distinct cell populationsof different organs. FASEB J 2003; 17(2): 271-3.
-
(2003)
FASEB J
, vol.17
, Issue.2
, pp. 271-273
-
-
Wiesener, M.S.1
Jurgensen, J.S.2
Rosenberger, C.3
-
230
-
-
0030879909
-
Regulation of humanplacental development by oxygen tension
-
Genbacev O, Zhou Y, Ludlow JW, Fisher SJ. Regulation of humanplacental development by oxygen tension. Science 1997;277(5332): 1669-72.
-
(1997)
Science
, vol.277
, Issue.5332
, pp. 1669-1672
-
-
Genbacev, O.1
Zhou, Y.2
Ludlow, J.W.3
Fisher, S.J.4
-
231
-
-
0035062024
-
Evaluation of respiratory gasesand acid-base gradients in human fetal fluids and uteroplacental tissuebetween 7 and 16 weeks' gestation
-
Jauniaux E, Watson A, Burton G. Evaluation of respiratory gasesand acid-base gradients in human fetal fluids and uteroplacental tissuebetween 7 and 16 weeks' gestation. Am J Obstet Gynecol 2001;184(5): 998-1003.
-
(2001)
Am J Obstet Gynecol
, vol.184
, Issue.5
, pp. 998-1003
-
-
Jauniaux, E.1
Watson, A.2
Burton, G.3
-
232
-
-
16344380951
-
Low O2 tensions and the preventionof differentiation of hES cells
-
Ezashi T, Das P, Roberts RM. Low O2 tensions and the preventionof differentiation of hES cells. Proc Natl Acad Sci USA 2005;102(13): 4783-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.13
, pp. 4783-4788
-
-
Ezashi, T.1
Das, P.2
Roberts, R.M.3
-
233
-
-
0027443181
-
The role of hypoxia in themaintenance of hematopoietic stem cells
-
Cipolleschi MG, Dello SP, Olivotto M. The role of hypoxia in themaintenance of hematopoietic stem cells. Blood 1993; 82(7): 2031-7.
-
(1993)
Blood
, vol.82
, Issue.7
, pp. 2031-2037
-
-
Cipolleschi, M.G.1
Dello, S.P.2
Olivotto, M.3
-
234
-
-
85047692887
-
Expansionof human SCID-repopulating cells under hypoxic conditions
-
Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC. Expansionof human SCID-repopulating cells under hypoxic conditions. J ClinInvest 2003; 112(1): 126-35.
-
(2003)
J ClinInvest
, vol.112
, Issue.1
, pp. 126-135
-
-
Danet, G.H.1
Pan, Y.2
Luongo, J.L.3
Bonnet, D.A.4
Simon, M.C.5
-
235
-
-
0034307432
-
Culture in reduced levels of oxygen promotes clonogenic sympathoadrenaldifferentiation by isolated neural crest stem cells
-
Morrison SJ, Csete M, Groves AK, Melega W, Wold B, Anderson DJ. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenaldifferentiation by isolated neural crest stem cells. JNeurosci 2000; 20(19): 7370-6.
-
(2000)
JNeurosci
, vol.20
, Issue.19
, pp. 7370-7376
-
-
Morrison, S.J.1
Csete, M.2
Groves, A.K.3
Melega, W.4
Wold, B.5
Anderson, D.J.6
-
236
-
-
0034307725
-
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in loweredoxygen
-
Studer L, Csete M, Lee SH, et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in loweredoxygen. J Neurosci 2000; 20(19): 7377-83.
-
(2000)
J Neurosci
, vol.20
, Issue.19
, pp. 7377-7383
-
-
Studer, L.1
Csete, M.2
Lee, S.H.3
-
237
-
-
0034466027
-
Oxygen and placental vascular development
-
Kingdom JC, Kaufmann P. Oxygen and placental vascular development. Adv Exp Med Biol 1999; 474: 259-75.
-
(1999)
Adv Exp Med Biol
, vol.474
, pp. 259-275
-
-
Kingdom, J.C.1
Kaufmann, P.2
-
238
-
-
78049283720
-
Regulation of hypoxiainducible factors (HIF) in hypoxia and normoxia during placentaldevelopment
-
Patel J, Landers K, Mortimer RH, Richard K. Regulation of hypoxiainducible factors (HIF) in hypoxia and normoxia during placentaldevelopment. Placenta 2010; 31(11): 951-7.
-
(2010)
Placenta
, vol.31
, Issue.11
, pp. 951-957
-
-
Patel, J.1
Landers, K.2
Mortimer, R.H.3
Richard, K.4
-
239
-
-
0034594876
-
Early expression of angiogenesis factors in acutemyocardial ischemia and infarction
-
Lee SH, Wolf PL, Escudero R, Deutsch R, Jamieson SW, Thistlethwaite PA. Early expression of angiogenesis factors in acutemyocardial ischemia and infarction. N Engl J Med 2000; 342(9):626-33.
-
(2000)
N Engl J Med
, vol.342
, Issue.9
, pp. 626-633
-
-
Lee, S.H.1
Wolf, P.L.2
Escudero, R.3
Deutsch, R.4
Jamieson, S.W.5
Thistlethwaite, P.A.6
-
240
-
-
0029033072
-
Ischaemiainducedexpression of bFGF in normal skeletal muscle: A potentialparacrine mechanism for mediating angiogenesis in ischaemicskeletal muscle
-
Walgenbach KJ, Gratas C, Shestak KC, Becker D. Ischaemiainducedexpression of bFGF in normal skeletal muscle: a potentialparacrine mechanism for mediating angiogenesis in ischaemicskeletal muscle. Nat Med 1995; 1(5): 453-9.
-
(1995)
Nat Med
, vol.1
, Issue.5
, pp. 453-459
-
-
Walgenbach, K.J.1
Gratas, C.2
Shestak, K.C.3
Becker, D.4
-
241
-
-
41149115123
-
The role of oxygen availability in embryonicdevelopment and stem cell function
-
Simon MC, Keith B. The role of oxygen availability in embryonicdevelopment and stem cell function. Nat Rev Mol Cell Biol 2008;9(4): 285-96.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.4
, pp. 285-296
-
-
Simon, M.C.1
Keith, B.2
-
242
-
-
84966192535
-
The histological structure of somehuman lung cancers and the possible implications for radiotherapy
-
Thomlinson RH, Gray LH. The histological structure of somehuman lung cancers and the possible implications for radiotherapy. Br J Cancer 1955; 9(4): 539-49.
-
(1955)
Br J Cancer
, vol.9
, Issue.4
, pp. 539-549
-
-
Thomlinson, R.H.1
Gray, L.H.2
-
243
-
-
0018176763
-
Rate of death of hypoxic cells in multicellspheroids
-
Franko AJ, Sutherland RM. Rate of death of hypoxic cells in multicellspheroids. Radiat Res 1978; 76(3): 561-72.
-
(1978)
Radiat Res
, vol.76
, Issue.3
, pp. 561-572
-
-
Franko, A.J.1
Sutherland, R.M.2
-
244
-
-
0032529245
-
Identification of nonproliferating butviable hypoxic tumor cells in vivo
-
Durand RE, Raleigh JA. Identification of nonproliferating butviable hypoxic tumor cells in vivo. Cancer Res 1998; 58(16): 3547-50.
-
(1998)
Cancer Res
, vol.58
, Issue.16
, pp. 3547-3550
-
-
Durand, R.E.1
Raleigh, J.A.2
-
245
-
-
4344707313
-
Quantifying transient hypoxia in humantumor xenografts by flow cytometry
-
Bennewith KL, Durand RE. Quantifying transient hypoxia in humantumor xenografts by flow cytometry. Cancer Res 2004;64(17): 6183-9.
-
(2004)
Cancer Res
, vol.64
, Issue.17
, pp. 6183-6189
-
-
Bennewith, K.L.1
Durand, R.E.2
-
246
-
-
33644506104
-
Direct demonstration of instabilities in oxygen concentrationswithin the extravascular compartment of an experimental tumor
-
Lanzen J, Braun RD, Klitzman B, Brizel D, Secomb TW, Dewhirst MW. Direct demonstration of instabilities in oxygen concentrationswithin the extravascular compartment of an experimental tumor. Cancer Res 2006; 66(4): 2219-23.
-
(2006)
Cancer Res
, vol.66
, Issue.4
, pp. 2219-2223
-
-
Lanzen, J.1
Braun, R.D.2
Klitzman, B.3
Brizel, D.4
Secomb, T.W.5
Dewhirst, M.W.6
-
248
-
-
22044450616
-
Phenotypic persistence afterreoxygenation of hypoxic neuroblastoma cells
-
Holmquist L, Jogi A, Pahlman S. Phenotypic persistence afterreoxygenation of hypoxic neuroblastoma cells. Int J Cancer 2005;116(2): 218-25.
-
(2005)
Int J Cancer
, vol.116
, Issue.2
, pp. 218-225
-
-
Holmquist, L.1
Jogi, A.2
Pahlman, S.3
-
249
-
-
60649097960
-
Cancer stem cells, hypoxia and metastasis
-
Hill RP, Marie-Egyptienne DT, Hedley DW. Cancer stem cells, hypoxia and metastasis. Semin Radiat Oncol 2009; 19(2): 106-11.
-
(2009)
Semin Radiat Oncol
, vol.19
, Issue.2
, pp. 106-111
-
-
Hill, R.P.1
Marie-Egyptienne, D.T.2
Hedley, D.W.3
-
250
-
-
70449687092
-
Hypoxia promotes expansion of theCD133-positive glioma stem cells through activation of HIF-1alpha
-
Soeda A, Park M, Lee D, et al. Hypoxia promotes expansion of theCD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 2009; 28(45): 3949-59.
-
(2009)
Oncogene
, vol.28
, Issue.45
, pp. 3949-3959
-
-
Soeda, A.1
Park, M.2
Lee, D.3
-
251
-
-
0037380791
-
Hypoxia promotes adedifferentiated phenotype in ductal breast carcinoma in situ
-
Helczynska K, Kronblad A, Jogi A, et al. Hypoxia promotes adedifferentiated phenotype in ductal breast carcinoma in situ. CancerRes 2003; 63(7): 1441-4.
-
(2003)
CancerRes
, vol.63
, Issue.7
, pp. 1441-1444
-
-
Helczynska, K.1
Kronblad, A.2
Jogi, A.3
-
252
-
-
40349088993
-
High levels of HIF-2alphahighlight an immature neural crest-like neuroblastoma cell cohortlocated in a perivascular niche
-
Pietras A, Gisselsson D, Ora I, et al. High levels of HIF-2alphahighlight an immature neural crest-like neuroblastoma cell cohortlocated in a perivascular niche. J Pathol 2008; 214(4): 482-8.
-
(2008)
J Pathol
, vol.214
, Issue.4
, pp. 482-488
-
-
Pietras, A.1
Gisselsson, D.2
Ora, I.3
-
253
-
-
79959908506
-
HIF induces human embryonicstem cell markers in cancer cells
-
Mathieu J, Zhang Z, Zhou W, et al. HIF induces human embryonicstem cell markers in cancer cells. Cancer Res 2011; 71(13): 4640-52.
-
(2011)
Cancer Res
, vol.71
, Issue.13
, pp. 4640-4652
-
-
Mathieu, J.1
Zhang, Z.2
Zhou, W.3
-
254
-
-
33644747418
-
HIF-2alpha regulates Oct-4:Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello KL, Kehler J, Yu H, et al. HIF-2alpha regulates Oct-4:effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006; 20(5): 557-70.
-
(2006)
Genes Dev
, vol.20
, Issue.5
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
-
255
-
-
13844280894
-
Oct4 expression in adult human stem cells: Evidence in support ofthe stem cell theory of carcinogenesis
-
Tai MH, Chang CC, Kiupel M, Webster JD, Olson LK, Trosko JE. Oct4 expression in adult human stem cells: evidence in support ofthe stem cell theory of carcinogenesis. Carcinogenesis 2005; 26(2):495-502.
-
(2005)
Carcinogenesis
, vol.26
, Issue.2
, pp. 495-502
-
-
Tai, M.H.1
Chang, C.C.2
Kiupel, M.3
Webster, J.D.4
Olson, L.K.5
Trosko, J.E.6
-
256
-
-
0344063368
-
Oct-3/4 is a dosedependentoncogenic fate determinant
-
Gidekel S, Pizov G, Bergman Y, Pikarsky E. Oct-3/4 is a dosedependentoncogenic fate determinant. Cancer Cell 2003; 4(5):361-70.
-
(2003)
Cancer Cell
, vol.4
, Issue.5
, pp. 361-370
-
-
Gidekel, S.1
Pizov, G.2
Bergman, Y.3
Pikarsky, E.4
-
257
-
-
54349087788
-
Myc's broad reach
-
Eilers M, Eisenman RN. Myc's broad reach. Genes Dev 2008;22(20): 2755-66.
-
(2008)
Genes Dev
, vol.22
, Issue.20
, pp. 2755-2766
-
-
Eilers, M.1
Eisenman, R.N.2
-
258
-
-
3142631736
-
HIF-1alpha induces cell cycle arrest by functionally counteractingMyc
-
Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, Huang LE. HIF-1alpha induces cell cycle arrest by functionally counteractingMyc. EMBO J 2004; 23(9): 1949-56.
-
(2004)
EMBO J
, vol.23
, Issue.9
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
259
-
-
34047156190
-
HIF-2alphapromotes hypoxic cell proliferation by enhancing c-myc transcriptionalactivity
-
Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC. HIF-2alphapromotes hypoxic cell proliferation by enhancing c-myc transcriptionalactivity. Cancer Cell 2007; 11(4): 335-47.
-
(2007)
Cancer Cell
, vol.11
, Issue.4
, pp. 335-347
-
-
Gordan, J.D.1
Bertout, J.A.2
Hu, C.J.3
Diehl, J.A.4
Simon, M.C.5
-
260
-
-
33747195353
-
Induction of pluripotent stem cells frommouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells frommouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126(4): 663-76.
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
261
-
-
34249909232
-
Directly reprogrammedfibroblasts show global epigenetic remodeling and widespread tissuecontribution
-
Maherali N, Sridharan R, Xie W, et al. Directly reprogrammedfibroblasts show global epigenetic remodeling and widespread tissuecontribution. Cell Stem Cell 2007; 1(1): 55-70.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
-
262
-
-
27644561755
-
Hypoxia requires notchsignaling to maintain the undifferentiated cell state
-
Gustafsson MV, Zheng X, Pereira T, et al. Hypoxia requires notchsignaling to maintain the undifferentiated cell state. Dev Cell 2005;9(5): 617-28.
-
(2005)
Dev Cell
, vol.9
, Issue.5
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
-
263
-
-
33747513134
-
Notchsignalling regulates stem cell numbers in vitro and in vivo
-
Androutsellis-Theotokis A, Leker RR, Soldner F, et al. Notchsignalling regulates stem cell numbers in vitro and in vivo. Nature2006; 442(7104): 823-6.
-
(2006)
Nature
, vol.442
, Issue.7104
, pp. 823-826
-
-
Androutsellis-Theotokis, A.1
Leker, R.R.2
Soldner, F.3
-
264
-
-
20544447734
-
Notch signals control the fate of immature progenitorcells in the intestine
-
Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S. Notch signals control the fate of immature progenitorcells in the intestine. Nature 2005; 435(7044): 964-8.
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 964-968
-
-
Fre, S.1
Huyghe, M.2
Mourikis, P.3
Robine, S.4
Louvard, D.5
Artavanis-Tsakonas, S.6
-
265
-
-
20544460148
-
Notch/gamma-secretaseinhibition turns proliferative cells in intestinal crypts and adenomasinto goblet cells
-
van Es JH, van Gijn ME, Riccio O, et al. Notch/gamma-secretaseinhibition turns proliferative cells in intestinal crypts and adenomasinto goblet cells. Nature 2005; 435(7044): 959-63.
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
-
266
-
-
0038404519
-
Notch1 but not Notch2 isessential for generating hematopoietic stem cells from endothelialcells
-
Kumano K, Chiba S, Kunisato A, et al. Notch1 but not Notch2 isessential for generating hematopoietic stem cells from endothelialcells. Immunity 2003; 18(5): 699-711.
-
(2003)
Immunity
, vol.18
, Issue.5
, pp. 699-711
-
-
Kumano, K.1
Chiba, S.2
Kunisato, A.3
-
267
-
-
84055194050
-
Low oxygen levels induce theexpression of the embryonic morphogen Nodal
-
Quail DF, Taylor M, Walsh L, et al. Low oxygen levels induce theexpression of the embryonic morphogen Nodal. Mol Biol Cell2011; 22(24): 4809-21.
-
(2011)
Mol Biol Cell
, vol.22
, Issue.24
, pp. 4809-4821
-
-
Quail, D.F.1
Taylor, M.2
Walsh, L.3
-
268
-
-
33947217823
-
Interaction between betacateninand HIF-1 promotes cellular adaptation to hypoxia
-
Kaidi A, Williams AC, Paraskeva C. Interaction between betacateninand HIF-1 promotes cellular adaptation to hypoxia. NatCell Biol 2007; 9(2): 210-7.
-
(2007)
NatCell Biol
, vol.9
, Issue.2
, pp. 210-217
-
-
Kaidi, A.1
Williams, A.C.2
Paraskeva, C.3
-
269
-
-
78650401560
-
HIF-2alpha enhances betacatenin/TCF-driven transcription by interacting with beta-catenin
-
Choi H, Chun YS, Kim TY, Park JW. HIF-2alpha enhances betacatenin/TCF-driven transcription by interacting with beta-catenin. Cancer Res 2010; 70(24): 10101-11.
-
(2010)
Cancer Res
, vol.70
, Issue.24
, pp. 10101-10111
-
-
Choi, H.1
Chun, Y.S.2
Kim, T.Y.3
Park, J.W.4
-
270
-
-
0037096732
-
Hypoxia-inducible factor-1-dependent regulationof the multidrug resistance (MDR1) gene
-
Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP. Hypoxia-inducible factor-1-dependent regulationof the multidrug resistance (MDR1) gene. Cancer Res 2002;62(12): 3387-94.
-
(2002)
Cancer Res
, vol.62
, Issue.12
, pp. 3387-3394
-
-
Comerford, K.M.1
Wallace, T.J.2
Karhausen, J.3
Louis, N.A.4
Montalto, M.C.5
Colgan, S.P.6
-
271
-
-
2642526992
-
The stem cellmarker Bcrp/ABCG2 enhances hypoxic cell survival through interactionswith heme
-
Krishnamurthy P, Ross DD, Nakanishi T, et al. The stem cellmarker Bcrp/ABCG2 enhances hypoxic cell survival through interactionswith heme. J Biol Chem 2004; 279(23): 24218-25.
-
(2004)
J Biol Chem
, vol.279
, Issue.23
, pp. 24218-24225
-
-
Krishnamurthy, P.1
Ross, D.D.2
Nakanishi, T.3
-
272
-
-
2942709631
-
Hypoxiainduciblefactor 1 mediates upregulation of telomerase (hTERT)
-
Nishi H, Nakada T, Kyo S, Inoue M, Shay JW, Isaka K. Hypoxiainduciblefactor 1 mediates upregulation of telomerase (hTERT). Mol Cell Biol 2004; 24(13): 6076-83.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.13
, pp. 6076-6083
-
-
Nishi, H.1
Nakada, T.2
Kyo, S.3
Inoue, M.4
Shay, J.W.5
Isaka, K.6
-
273
-
-
33747691662
-
Transforming growth factor beta1 induces hypoxia-induciblefactor-1 stabilization through selective inhibition of PHD2 expression
-
McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM. Transforming growth factor beta1 induces hypoxia-induciblefactor-1 stabilization through selective inhibition of PHD2 expression. J Biol Chem 2006; 281(34): 24171-81.
-
(2006)
J Biol Chem
, vol.281
, Issue.34
, pp. 24171-24181
-
-
McMahon, S.1
Charbonneau, M.2
Grandmont, S.3
Richard, D.E.4
Dubois, C.M.5
-
274
-
-
79956219871
-
Hypoxia activates the hedgehogsignaling pathway in a ligand-independent manner by upregulationof Smo transcription in pancreatic cancer
-
Onishi H, Kai M, Odate S, et al. Hypoxia activates the hedgehogsignaling pathway in a ligand-independent manner by upregulationof Smo transcription in pancreatic cancer. Cancer Sci 2011; 102(6):1144-50.
-
(2011)
Cancer Sci
, vol.102
, Issue.6
, pp. 1144-1150
-
-
Onishi, H.1
Kai, M.2
Odate, S.3
|