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Volumn 44, Issue 6, 2012, Pages 980-988

Standardized mitochondrial analysis gives new insights into mitochondrial dynamics and OPA1 function

Author keywords

MFN2; Microtubule organizing centre; Mitochondrial dynamics; Neurodegeneration; OPA1

Indexed keywords

ADULT; AGING; ARTICLE; BIOGENESIS; CASE REPORT; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CHILD; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; GENE; GENE FUNCTION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MFN2 GENE; MICROTUBULE ORGANIZING CENTER; MITOCHONDRION; OPA1 GENE; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SKIN FIBROBLAST;

EID: 84860278022     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.03.006     Document Type: Article
Times cited : (37)

References (49)
  • 4
    • 42749094176 scopus 로고    scopus 로고
    • Mitochondrial fusion and function in Charcot-Marie-Tooth Type 2a patient fibroblasts with mitofusin 2 mutations
    • E.A. Amiott, P. Lott, J. Soto, P.B. Kang, J.M. McCaffery, and S. DiMauro Mitochondrial fusion and function in Charcot-Marie-Tooth Type 2a patient fibroblasts with mitofusin 2 mutations Exp Neurol 211 2008 115 127
    • (2008) Exp Neurol , vol.211 , pp. 115-127
    • Amiott, E.A.1    Lott, P.2    Soto, J.3    Kang, P.B.4    McCaffery, J.M.5    Dimauro, S.6
  • 6
    • 51749084230 scopus 로고    scopus 로고
    • Ultrastructure of the mitochondrion and its bearing on function and bioenergetics
    • G. Benard, and R. Rossignol Ultrastructure of the mitochondrion and its bearing on function and bioenergetics Antioxid Redox Signal 10 2008 1313 1342
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1313-1342
    • Benard, G.1    Rossignol, R.2
  • 7
    • 78650934995 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and pathophysiology of Charcot-Marie-Tooth disease involving Gdap1 mutations
    • J. Cassereau, A. Chevrollier, N. Gueguen, V. Desquiret, C. Verny, and G. Nicolas Mitochondrial dysfunction and pathophysiology of Charcot-Marie-Tooth disease involving Gdap1 mutations Exp Neurol 227 2011 31 41
    • (2011) Exp Neurol , vol.227 , pp. 31-41
    • Cassereau, J.1    Chevrollier, A.2    Gueguen, N.3    Desquiret, V.4    Verny, C.5    Nicolas, G.6
  • 8
    • 0002896804 scopus 로고
    • Une Forme Particulire D'atrophie Musculaire Progressive, Souvent Familiale Débutant Par les Pieds et les Jambes et Atteignant Plus Tard les Mains
    • J.M. Charcot, and M.P. Sur Une Forme Particulire D'atrophie Musculaire Progressive, Souvent Familiale Débutant Par Les Pieds Et Les Jambes Et Atteignant Plus Tard Les Mains Rev Med 6 1886 97 138
    • (1886) Rev Med , vol.6 , pp. 97-138
    • Charcot, J.M.1    Sur, M.P.2
  • 9
    • 77951096150 scopus 로고    scopus 로고
    • Mitochondrial dynamics - Fusion, fission, movement, and mitophagy - In neurodegenerative diseases
    • H. Chen, and D.C. Chan Mitochondrial dynamics - fusion, fission, movement, and mitophagy - in neurodegenerative diseases Hum Mol Genet 18 2009 R169 R176
    • (2009) Hum Mol Genet , vol.18
    • Chen, H.1    Chan, D.C.2
  • 10
    • 64249133725 scopus 로고    scopus 로고
    • S-Nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
    • D.H. Cho, T. Nakamura, J. Fang, P. Cieplak, A. Godzik, and Z. Gu S-Nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury Science 324 2009 102 105
    • (2009) Science , vol.324 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3    Cieplak, P.4    Godzik, A.5    Gu, Z.6
  • 12
    • 0037007227 scopus 로고    scopus 로고
    • Mitochondria are morphologically and functionally heterogeneous within cells
    • DOI 10.1093/emboj/21.7.1616
    • T.J. Collins, M.J. Berridge, P. Lipp, and M.D. Bootman Mitochondria are morphologically and functionally heterogeneous within cells EMBO J 21 2002 1616 1627 (Pubitemid 34614618)
    • (2002) EMBO Journal , vol.21 , Issue.7 , pp. 1616-1627
    • Collins, T.J.1    Berridge, M.J.2    Lipp, P.3    Bootman, M.D.4
  • 13
    • 35448960851 scopus 로고    scopus 로고
    • Functions and dysfunctions of mitochondrial dynamics
    • DOI 10.1038/nrm2275, PII NRM2275
    • S.A. Detmer, and D.C. Chan Functions and dysfunctions of mitochondrial dynamics Nat Rev Mol Cell Biol 8 2007 870 879 (Pubitemid 47622562)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.11 , pp. 870-879
    • Detmer, S.A.1    Chan, D.C.2
  • 14
    • 78651480831 scopus 로고    scopus 로고
    • Opa1 links human mitochondrial genome maintenance to mtDNA replication and distribution
    • G. Elachouri, S. Vidoni, C. Zanna, A. Pattyn, H. Boukhaddaoui, and K. Gaget Opa1 links human mitochondrial genome maintenance to mtDNA replication and distribution Genome Res 21 2011 12 20
    • (2011) Genome Res , vol.21 , pp. 12-20
    • Elachouri, G.1    Vidoni, S.2    Zanna, C.3    Pattyn, A.4    Boukhaddaoui, H.5    Gaget, K.6
  • 15
    • 67649658061 scopus 로고    scopus 로고
    • Molecular screening of 980 cases of suspected hereditary optic neuropathy with a report on 77 novel OPA1 mutations
    • M. Ferré, D. Bonneau, D. Milea, A. Chevrollier, C. Verny, and H. Dollfus Molecular screening of 980 cases of suspected hereditary optic neuropathy with a report on 77 novel OPA1 mutations Hum Mutat 30 2009 E692 E705
    • (2009) Hum Mutat , vol.30
    • Ferré, M.1    Bonneau, D.2    Milea, D.3    Chevrollier, A.4    Verny, C.5    Dollfus, H.6
  • 16
    • 0030046495 scopus 로고    scopus 로고
    • Mitochondria and diabetes: Genetic, biochemical, and clinical implications of the cellular energy circuit
    • K.D. Gerbitz, K. Gempel, and D. Brdiczka Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit Diabetes 45 1996 113 126 (Pubitemid 26045791)
    • (1996) Diabetes , vol.45 , Issue.2 , pp. 113-126
    • Gerbitz, K.-D.1    Gempel, K.2    Brdiczka, D.3
  • 17
    • 38649132337 scopus 로고    scopus 로고
    • Mitochondria-A Nexus for Aging, Calorie Restriction, and Sirtuins?
    • DOI 10.1016/j.cell.2008.01.007, PII S0092867408000627
    • L. Guarente Mitochondria - a Nexus for aging, calorie restriction, and sirtuins Cell 132 2008 171 176 (Pubitemid 351172441)
    • (2008) Cell , vol.132 , Issue.2 , pp. 171-176
    • Guarente, L.1
  • 18
    • 3042781117 scopus 로고    scopus 로고
    • Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts
    • DOI 10.1042/BJ20040095
    • E. Hutter, K. Renner, G. Pfister, P. Stockl, P. Jansen-Durr, and E. Gnaiger Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts Biochem J 380 2004 919 928 (Pubitemid 38850535)
    • (2004) Biochemical Journal , vol.380 , Issue.3 , pp. 919-928
    • Hutter, E.1    Renner, K.2    Pfister, G.3    Stockl, P.4    Jansen-Durr, P.5    Gnaiger, E.6
  • 20
    • 1242307475 scopus 로고    scopus 로고
    • Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis
    • DOI 10.1083/jcb.200309082
    • M. Karbowski, D. Arnoult, H. Chen, D.C. Chan, C.L. Smith, and R.J. Youle Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the bax activation phase of apoptosis J Cell Biol 164 2004 493 499 (Pubitemid 38233310)
    • (2004) Journal of Cell Biology , vol.164 , Issue.4 , pp. 493-499
    • Karbowski, M.1    Arnoult, D.2    Chen, H.3    Chan, D.C.4    Smith, C.L.5    Youle, R.J.6
  • 21
    • 30344453413 scopus 로고    scopus 로고
    • Simultaneous quantitative measurement and automated analysis of mitochondrial morphology, mass, potential, and motility in living human skin fibroblasts
    • DOI 10.1002/cyto.a.20198
    • W.J. Koopman, H.J. Visch, J.A. Smeitink, and P.H. Willems Simultaneous quantitative measurement and automated analysis of mitochondrial morphology, mass, potential, and motility in living human skin fibroblasts Cytometry A 69 2006 1 12 (Pubitemid 43062691)
    • (2006) Cytometry Part A , vol.69 , Issue.1 , pp. 1-12
    • Koopman, W.J.H.1    Visch, H.-J.2    Smeitink, J.A.M.3    Willems, P.H.G.M.4
  • 25
    • 34250624810 scopus 로고    scopus 로고
    • A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases
    • DOI 10.1242/jcs.03443
    • W. Mandemakers, V.A. Morais, and B. De Strooper A cell biological perspective on mitochondrial dysfunction in parkinson disease and other neurodegenerative diseases J Cell Sci 120 2007 1707 1716 (Pubitemid 46930408)
    • (2007) Journal of Cell Science , vol.120 , Issue.10 , pp. 1707-1716
    • Mandemakers, W.1    Morais, V.A.2    De Strooper, B.3
  • 26
    • 77949614390 scopus 로고    scopus 로고
    • Analysis of mitochondrial dynamics and functions using imaging approaches
    • [chapter 4, Unit 4]
    • K. Mitra, and J. Lippincott-Schwartz Analysis of mitochondrial dynamics and functions using imaging approaches Curr Protoc Cell Biol 25 2010 21 [chapter 4, Unit 4]
    • (2010) Curr Protoc Cell Biol , vol.25 , pp. 21
    • Mitra, K.1    Lippincott-Schwartz, J.2
  • 27
    • 67749089562 scopus 로고    scopus 로고
    • A hyperfused mitochondrial state achieved at G1-S regulates cyclin e buildup and entry into S phase
    • K. Mitra, C. Wunder, B. Roysam, G. Lin, and J. Lippincott-Schwartz A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase Proc Natl Acad Sci USA 106 2009 11960 11965
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11960-11965
    • Mitra, K.1    Wunder, C.2    Roysam, B.3    Lin, G.4    Lippincott-Schwartz, J.5
  • 28
    • 33644519916 scopus 로고    scopus 로고
    • Novel mutations in the OPA1 gene and associated clinical features in japanese patients with optic atrophy
    • e481
    • M. Nakamura, J. Lin, S. Ueno, R. Asaoka, T. Hirai, and Y. Hotta Novel mutations in the OPA1 gene and associated clinical features in japanese patients with optic atrophy Ophthalmology 113 2006 483 488 e481
    • (2006) Ophthalmology , vol.113 , pp. 483-488
    • Nakamura, M.1    Lin, J.2    Ueno, S.3    Asaoka, R.4    Hirai, T.5    Hotta, Y.6
  • 29
    • 79957976176 scopus 로고    scopus 로고
    • Two-color sted microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms
    • D. Neumann, J. Buckers, L. Kastrup, S.W. Hell, and S. Jakobs Two-color sted microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms PMC Biophys 3 2010 4
    • (2010) PMC Biophys , vol.3 , pp. 4
    • Neumann, D.1    Buckers, J.2    Kastrup, L.3    Hell, S.W.4    Jakobs, S.5
  • 30
    • 34247094215 scopus 로고    scopus 로고
    • Mitofusin 2 gene mutation (R94Q) causing severe early-onset axonal polyneuropathy (CMT2A)
    • DOI 10.1111/j.1468-1331.2006.01688.x
    • C. Neusch, J. Senderek, T. Eggermann, E. Elolff, M. Bahr, and C. Schneider-Gold Mitofusin 2 gene mutation (R94q) causing severe early-onset axonal polyneuropathy (CMT2A) Eur J Neurol 14 2007 575 577 (Pubitemid 46587825)
    • (2007) European Journal of Neurology , vol.14 , Issue.5 , pp. 575-577
    • Neusch, C.1    Senderek, J.2    Eggermann, T.3    Elolff, E.4    Bahr, M.5    Schneider-Gold, C.6
  • 31
    • 70350348361 scopus 로고    scopus 로고
    • Gdap1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance
    • A. Niemann, K.M. Wagner, M. Ruegg, and U. Suter Gdap1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance Neurobiol Dis 36 2009 509 520
    • (2009) Neurobiol Dis , vol.36 , pp. 509-520
    • Niemann, A.1    Wagner, K.M.2    Ruegg, M.3    Suter, U.4
  • 33
    • 46649095406 scopus 로고    scopus 로고
    • Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in Ins-1e and Hep-G2 cells viewed by 4pi microscopy
    • L. Plecita-Hlavata, M. Lessard, J. Santorova, J. Bewersdorf, and P. Jezek Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in Ins-1e and Hep-G2 cells viewed by 4pi microscopy Biochim Biophys Acta 1777 2008 834 846
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 834-846
    • Plecita-Hlavata, L.1    Lessard, M.2    Santorova, J.3    Bewersdorf, J.4    Jezek, P.5
  • 34
    • 0037089084 scopus 로고    scopus 로고
    • Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
    • M. Rojo, F. Legros, D. Chateau, and A. Lombes Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane Gtpase Fzo J Cell Sci 115 2002 1663 1674 (Pubitemid 34520596)
    • (2002) Journal of Cell Science , vol.115 , Issue.8 , pp. 1663-1674
    • Rojo, M.1    Legros, F.2    Chateau, D.3    Lombes, A.4
  • 37
    • 0035057837 scopus 로고    scopus 로고
    • Control of mitochondrial morphology by a human mitofusin
    • A. Santel, and M.T. Fuller Control of mitochondrial morphology by a human mitofusin J Cell Sci 114 2001 867 874 (Pubitemid 32266258)
    • (2001) Journal of Cell Science , vol.114 , Issue.5 , pp. 867-874
    • Santel, A.1    Fuller, M.T.2
  • 38
    • 77955273254 scopus 로고    scopus 로고
    • Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics
    • C. Sauvanet, S. Duvezin-Caubet, J.P. di Rago, and M. Rojo Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics Semin Cell Dev Biol 21 2010 558 565
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 558-565
    • Sauvanet, C.1    Duvezin-Caubet, S.2    Di Rago, J.P.3    Rojo, M.4
  • 39
    • 33745410626 scopus 로고    scopus 로고
    • Mitochondrial disease
    • DOI 10.1016/S0140-6736(06)68970-8, PII S0140673606689708
    • A.H. Schapira Mitochondrial disease Lancet 368 2006 70 82 (Pubitemid 43947206)
    • (2006) Lancet , vol.368 , Issue.9529 , pp. 70-82
    • Schapira, A.H.1
  • 41
    • 67649859266 scopus 로고    scopus 로고
    • Par3 and Dynein associate to regulate local microtubule dynamics and centrosome orientation during migration
    • J. Schmoranzer, J.P. Fawcett, M. Segura, S. Tan, R.B. Vallee, and T. Pawson Par3 and Dynein associate to regulate local microtubule dynamics and centrosome orientation during migration Curr Biol 19 2009 1065 1074
    • (2009) Curr Biol , vol.19 , pp. 1065-1074
    • Schmoranzer, J.1    Fawcett, J.P.2    Segura, M.3    Tan, S.4    Vallee, R.B.5    Pawson, T.6
  • 42
    • 79952443408 scopus 로고    scopus 로고
    • Mutant huntingtin binds the mitochondrial fission gtpase dynamin-related protein-1 and increases its enzymatic activity
    • W. Song, J. Chen, A. Petrilli, G. Liot, E. Klinglmayr, and Y. Zhou Mutant huntingtin binds the mitochondrial fission gtpase dynamin-related protein-1 and increases its enzymatic activity Nat Med 17 2011 377 382
    • (2011) Nat Med , vol.17 , pp. 377-382
    • Song, W.1    Chen, J.2    Petrilli, A.3    Liot, G.4    Klinglmayr, E.5    Zhou, Y.6
  • 44
    • 77955865509 scopus 로고    scopus 로고
    • Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity
    • G. Twig, X. Liu, M. Liesa, J.D. Wikstrom, A.J. Molina, and G. Las Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity Am J Physiol Cell Physiol 299 2010 C477 C487
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Twig, G.1    Liu, X.2    Liesa, M.3    Wikstrom, J.D.4    Molina, A.J.5    Las, G.6
  • 48
    • 78649413837 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in cell life and death
    • B. Westermann Mitochondrial fusion and fission in cell life and death Nat Rev Mol Cell Biol 11 2010 872 884
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 872-884
    • Westermann, B.1
  • 49
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila Parkin requires Pink1 for mitochondrial translocation and ubiquitinates mitofusin
    • E. Ziviani, R.N. Tao, and A.J. Whitworth Drosophila Parkin requires Pink1 for mitochondrial translocation and ubiquitinates mitofusin Proc Natl Acad Sci USA 107 2010 5018 5023
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3


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