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Volumn 42, Issue 1, 2012, Pages 221-229

EAAT expression by macrophages and microglia: Still more questions than answers

Author keywords

EAAT; Glutamate; Glutathione; Macrophage; Microglia; Neuroinflammation; XCT

Indexed keywords

CYSTINE; CYSTINE GLUTAMATE EXCHANGER; EXCITATORY AMINO ACID; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; PROTEIN; UNCLASSIFIED DRUG; GLUTAMATE TRANSPORTER;

EID: 84860238593     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-011-0866-6     Document Type: Conference Paper
Times cited : (36)

References (106)
  • 1
    • 33947363967 scopus 로고    scopus 로고
    • 377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease
    • DOI 10.1084/jem.20061931
    • Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K (2007) The fibrin-derived gamma 377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. J Exp Med 204:571-582 (Pubitemid 46457080)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.3 , pp. 571-582
    • Adams, R.A.1    Bauer, J.2    Flick, M.J.3    Sikorski, S.L.4    Nuriel, T.5    Lassmann, H.6    Degen, J.L.7    Akassoglou, K.8
  • 2
    • 0032737272 scopus 로고    scopus 로고
    • Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
    • DOI 10.1016/S0165-3806(99)00113-3, PII S0165380699001133
    • Alliot F, Godin I, Pessac B (1999) Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain. Brain Res Dev Brain Res 117:145-152 (Pubitemid 29531505)
    • (1999) Developmental Brain Research , vol.117 , Issue.2 , pp. 145-152
    • Alliot, F.1    Godin, I.2    Pessac, B.3
  • 3
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • DOI 10.1038/nn1609
    • Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, Swanson RA (2006) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci 9:119-126 (Pubitemid 43011917)
    • (2006) Nature Neuroscience , vol.9 , Issue.1 , pp. 119-126
    • Aoyama, K.1    Sang, W.S.2    Hamby, A.M.3    Liu, J.4    Wai, Y.C.5    Chen, Y.6    Swanson, R.A.7
  • 5
    • 0027376769 scopus 로고
    • Nonvesicular release of neurotransmitter
    • DOI 10.1016/0896-6273(93)90145-H
    • Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11:401-407 (Pubitemid 23287068)
    • (1993) Neuron , vol.11 , Issue.3 , pp. 401-407
    • Attwell, D.1    Barbour, B.2    Szatkowski, M.3
  • 6
    • 0022969399 scopus 로고
    • Exchange of cystine and glutamate across plasma membrane of human fibroblasts
    • Bannai S (1986) Exchange of cystine and glutamate across plasma membrane of human fibroblasts. J Biol Chem 261:2256-2263 (Pubitemid 17205155)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.5 , pp. 2256-2263
    • Bannai, S.1
  • 7
    • 0038469628 scopus 로고    scopus 로고
    • Transfer of glutamine between astrocytes and neurons
    • DOI 10.1046/j.1471-4159.2001.00322.x
    • Broer S, Brookes N (2001) Transfer of glutamine between astrocytes and neurons. J Neurochem 77:705-719 (Pubitemid 32466769)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.3 , pp. 705-719
    • Broer, S.1    Brookes, N.2
  • 9
    • 0037449150 scopus 로고    scopus 로고
    • Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures
    • DOI 10.1016/S0006-8993(03)02517-4
    • Brooke SM, Sapolsky RM (2003) Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res 972:137-141 (Pubitemid 36507085)
    • (2003) Brain Research , vol.972 , Issue.1-2 , pp. 137-141
    • Brooke, S.M.1    Sapolsky, R.M.2
  • 10
    • 0001930725 scopus 로고    scopus 로고
    • Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli
    • Buechler C, Ritter M, Orso E, Langmann T, Klucken J, Schmitz G (2000) Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli. J Leukoc Biol 67:97-103 (Pubitemid 30046823)
    • (2000) Journal of Leukocyte Biology , vol.67 , Issue.1 , pp. 97-103
    • Buechler, C.1    Ritter, M.2    Orso, E.3    Langmann, T.4    Klucken, J.5    Schmitz, G.6
  • 11
    • 57749093019 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders
    • Byrnes KR, Loane DJ, Faden AI (2009) Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders. Neurotherapeutics 6:94-107
    • (2009) Neurotherapeutics , vol.6 , pp. 94-107
    • Byrnes, K.R.1    Loane, D.J.2    Faden, A.I.3
  • 13
    • 0033598956 scopus 로고    scopus 로고
    • Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission
    • Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (1999) Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell 99:769-780 (Pubitemid 30017647)
    • (1999) Cell , vol.99 , Issue.7 , pp. 769-780
    • Chaudhry, F.A.1    Reimer, R.J.2    Krizaj, D.3    Barber, D.4    Storm-Mathisen, J.5    Copenhagen, D.R.6    Edwards, R.H.7
  • 17
    • 0034019630 scopus 로고    scopus 로고
    • Compartmentation of brain glutamate metabolism in neurons and glia
    • Daikhin Y, Yudkoff M (2000) Compartmentation of brain glutamate metabolism in neurons and glia. J Nutr 130:1026S-1031S (Pubitemid 30173638)
    • (2000) Journal of Nutrition , vol.130 , Issue.4 SUPPL.
    • Daikhin, Y.1    Yudkoff, M.2
  • 19
  • 20
    • 3142694174 scopus 로고    scopus 로고
    • Atypical antiinflammatory activation of microglia induced by apoptotic neurons: Possible role of phosphatidylserine-phosphatidylserine receptor interaction
    • DOI 10.1385/MN:29:2:197
    • De Simone R, Ajmone-Cat MA, Minghetti L (2004) Atypical antiinflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction. Mol Neurobiol 29:197-212 (Pubitemid 40104482)
    • (2004) Molecular Neurobiology , vol.29 , Issue.2 , pp. 197-212
    • De Simone, R.1    Ajmone-Cat, M.A.2    Minghetti, L.3
  • 21
    • 0025878379 scopus 로고
    • Astroglial processes around identified glutamatergic synapses contain glutamine synthetase: Evidence for transmitter degradation
    • Derouiche A, Frotscher M (1991) Astroglial processes around identified glutamatergic synapses contain glutamine synthetase: evidence for transmitter degradation. Brain Res 552:346-350
    • (1991) Brain Res , vol.552 , pp. 346-350
    • Derouiche, A.1    Frotscher, M.2
  • 22
    • 0029120602 scopus 로고
    • Coincidence of L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: Evidence for coupling of GLAST and GS in transmitter clearance
    • Derouiche A, Rauen T (1995) Coincidence of L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: evidence for coupling of GLAST and GS in transmitter clearance. J Neurosci Res 42:131-143
    • (1995) J Neurosci Res , vol.42 , pp. 131-143
    • Derouiche, A.1    Rauen, T.2
  • 23
    • 0029859733 scopus 로고    scopus 로고
    • Spatial relationship of lectin-labelled extracellular matrix and glutamine synthetase-immunoreactive astrocytes in rat cortical forebrain regions
    • Derouiche A, Hartig W, Brauer K, Bruckner G (1996) Spatial relationship of lectin-labelled extracellular matrix and glutamine synthetase-immunoreactive astrocytes in rat cortical forebrain regions. J Anat 189:363-372 (Pubitemid 26364692)
    • (1996) Journal of Anatomy , vol.189 , Issue.2 , pp. 363-372
    • Derouiche, A.1    Hartig, W.2    Brauer, K.3    Bruckner, G.4
  • 24
    • 0028847323 scopus 로고
    • The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid
    • Dreyer EB, Lipton SA (1995) The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid. Eur J Neurosci 7:2502-2507
    • (1995) Eur J Neurosci , vol.7 , pp. 2502-2507
    • Dreyer, E.B.1    Lipton, S.A.2
  • 26
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375:599-603
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 27
    • 0041736717 scopus 로고    scopus 로고
    • Regulation of glial glutamate transporter expression by growth factors
    • DOI 10.1016/S0014-4886(03)00134-1
    • Figiel M, Maucher T, Rozyczka J, Bayatti N, Engele J (2003) Regulation of glial glutamate transporter expression by growth factors. Exp Neurol 183:124-135 (Pubitemid 37075863)
    • (2003) Experimental Neurology , vol.183 , Issue.1 , pp. 124-135
    • Figiel, M.1    Maucher, T.2    Rozyczka, J.3    Bayatti, N.4    Engele, J.5
  • 28
    • 0029943301 scopus 로고    scopus 로고
    • Tumor necrosis factor α inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia
    • DOI 10.1074/jbc.271.26.15303
    • Fine SM, Angel RA, Perry SW, Epstein LG, Rothstein JD, Dewhurst S, Gelbard HA (1996) Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. J Biol Chem 271:15303-15306 (Pubitemid 26225294)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.26 , pp. 15303-15306
    • Fine, S.M.1    Angel, R.A.2    Perry, S.W.3    Epstein, L.G.4    Rothstein, J.D.5    Dewhurst, S.6    Gelbard, H.A.7
  • 29
    • 0021330769 scopus 로고
    • Glutamate: A neurotransmitter in mammalian brain
    • Fonnum F (1984) Glutamate: a neurotransmitter in mammalian brain. J Neurochem 42:1-11 (Pubitemid 14216942)
    • (1984) Journal of Neurochemistry , vol.42 , Issue.1 , pp. 1-11
    • Fonnum, F.1
  • 31
    • 13544270278 scopus 로고    scopus 로고
    • Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain
    • DOI 10.1002/glia.20124
    • Galea I, Palin K, Newman TA, Van Rooijen N, Perry VH, Boche D (2005) Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain. Glia 49:375-384 (Pubitemid 40222915)
    • (2005) GLIA , vol.49 , Issue.3 , pp. 375-384
    • Galea, I.1    Palin, K.2    Newman, T.A.3    Van Rooijen, N.4    Perry, V.H.5    Boche, D.6
  • 32
    • 0030840881 scopus 로고    scopus 로고
    • High affinity glutamate transporters: Regulation of expression and activity
    • Gegelashvili G, Schousboe A (1997) High affinity glutamate transporters: regulation of expression and activity. Mol Pharmacol 52:6-15 (Pubitemid 27318612)
    • (1997) Molecular Pharmacology , vol.52 , Issue.1 , pp. 6-15
    • Gegelashvili, G.1    Schousboe, A.2
  • 33
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • DOI 10.1016/S1074-7613(03)00174-2
    • Geissmann F, Jung S, Littman DR (2003) Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19:71-82 (Pubitemid 36859902)
    • (2003) Immunity , vol.19 , Issue.1 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 35
    • 33750481898 scopus 로고    scopus 로고
    • The glutamate-glutamine cycle as an inducible, protective face of macrophage activation
    • DOI 10.1189/jlb.0306153
    • Gras G, Porcheray F, Samah B, Leone C (2006) The glutamate-glutamine cycle as an inducible, protective face of macrophage activation. J Leukoc Biol 80:1067-1075 (Pubitemid 44646312)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.5 , pp. 1067-1075
    • Gras, G.1    Porcheray, F.2    Samah, B.3    Leone, C.4
  • 37
    • 84862645388 scopus 로고    scopus 로고
    • Toward a new role for plasma membrane sodium-dependent glutamate transporters of astrocytes: Maintenance of antioxidant defenses beyond extracellular glutamate clearance
    • (this issue)
    • Had-Aissouni L (2011) Toward a new role for plasma membrane sodium-dependent glutamate transporters of astrocytes: maintenance of antioxidant defenses beyond extracellular glutamate clearance. Amino Acids (this issue)
    • (2011) Amino Acids
    • Had-Aissouni, L.1
  • 38
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
    • DOI 10.1038/nn1997, PII NN1997
    • Hanisch UK, Kettenmann H (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10:1387-1394 (Pubitemid 350014685)
    • (2007) Nature Neuroscience , vol.10 , Issue.11 , pp. 1387-1394
    • Hanisch, U.-K.1    Kettenmann, H.2
  • 39
    • 0347991771 scopus 로고    scopus 로고
    • Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons
    • DOI 10.1007/s00702-003-0049-z
    • Himi T, Ikeda M, Yasuhara T, Nishida M, Morita I (2003) Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons. J Neural Transm 110:1337-1348 (Pubitemid 38041341)
    • (2003) Journal of Neural Transmission , vol.110 , Issue.12 , pp. 1337-1348
    • Himi, T.1    Ikeda, M.2    Yasuhara, T.3    Nishida, M.4    Morita, I.5
  • 40
    • 0032529409 scopus 로고    scopus 로고
    • Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163)
    • Hogger P, Dreier J, Droste A, Buck F, Sorg C (1998) Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid- inducible member of the scavenger receptor cysteine-rich family (CD163). J Immunol 161:1883-1890 (Pubitemid 28387610)
    • (1998) Journal of Immunology , vol.161 , Issue.4 , pp. 1883-1890
    • Hogger, P.1    Dreier, J.2    Droste, A.3    Buck, F.4    Sorg, C.5
  • 41
    • 33645871603 scopus 로고    scopus 로고
    • Corticosterone inhibits expression of the microglial glutamate transporter GLT-1 in vitro
    • Jacobsson J, Persson M, Hansson E, Ronnback L (2006) Corticosterone inhibits expression of the microglial glutamate transporter GLT-1 in vitro. Neuroscience 139:475-483
    • (2006) Neuroscience , vol.139 , pp. 475-483
    • Jacobsson, J.1    Persson, M.2    Hansson, E.3    Ronnback, L.4
  • 43
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai Y, Hediger MA (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360:467-471
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 44
    • 20444389341 scopus 로고    scopus 로고
    • Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1
    • DOI 10.1016/j.gene.2005.04.006, PII S0378111905001940
    • Kang DC, Su ZZ, Sarkar D, Emdad L, Volsky DJ, Fisher PB (2005) Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene 353:8-15 (Pubitemid 40805356)
    • (2005) Gene , vol.353 , Issue.1 , pp. 8-15
    • Kang, D.-C.1    Su, Z.-Z.2    Sarkar, D.3    Emdad, L.4    Volsky, D.J.5    Fisher, P.B.6
  • 45
    • 39849083520 scopus 로고    scopus 로고
    • Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
    • DOI 10.1523/JNEUROSCI.5643-07.2008
    • Kaushal V, Schlichter LC (2008) Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J Neurosci 28:2221-2230 (Pubitemid 351317617)
    • (2008) Journal of Neuroscience , vol.28 , Issue.9 , pp. 2221-2230
    • Kaushal, V.1    Schlichter, L.C.2
  • 46
    • 0027170019 scopus 로고
    • Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages
    • Kida S, Steart PV, Zhang ET, Weller RO (1993) Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages. Acta Neuropathol 85:646-652 (Pubitemid 23212032)
    • (1993) Acta Neuropathologica , vol.85 , Issue.6 , pp. 646-652
    • Kida, S.1    Steart, P.V.2    Zhang, E.-T.3    Weller, R.O.4
  • 47
    • 0028577734 scopus 로고
    • Dissection of macrophage differentiation pathways in cutaneous macrophage disorders and in vitro
    • Kodelja V, Goerdt S (1994) Dissection of macrophage differentiation pathways in cutaneous macrophage disorders and in vitro. Exp Dermatol 3:257-268
    • (1994) Exp Dermatol , vol.3 , pp. 257-268
    • Kodelja, V.1    Goerdt, S.2
  • 49
    • 0032505644 scopus 로고    scopus 로고
    • Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1
    • Kort JJ (1998) Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 14:1329-1339 (Pubitemid 28465267)
    • (1998) AIDS Research and Human Retroviruses , vol.14 , Issue.15 , pp. 1329-1339
    • Kort, J.J.1
  • 50
    • 0026552605 scopus 로고
    • Turnover of resident microglia in the normal adult mouse brain
    • Lawson LJ, Perry VH, Gordon S (1992) Turnover of resident microglia in the normal adult mouse brain. Neuroscience 48:405-415
    • (1992) Neuroscience , vol.48 , pp. 405-415
    • Lawson, L.J.1    Perry, V.H.2    Gordon, S.3
  • 51
    • 0021031723 scopus 로고
    • 3H]acetylcholine release in striatal slices: Mediation by NMDA-type excitatory amino acid receptors
    • Lehmann J, Schaefer P, Ferkany JW, Coyle JT (1983) Quinolinic acid evokes [3H]acetylcholine release in striatal slices: mediation by NMDA-type excitatory amino acid receptors. Eur J Pharmacol 96:111-115 (Pubitemid 14222417)
    • (1983) European Journal of Pharmacology , vol.96 , Issue.1-2 , pp. 111-115
    • Lehmann, J.1    Schaefer, P.2    Ferkany, J.W.3    Coyle, J.T.4
  • 52
    • 33747202172 scopus 로고    scopus 로고
    • Characterization of human monocyte-derived microglia-like cells
    • DOI 10.1002/glia.20372
    • Leone C, Le Pavec G, Meme W, Porcheray F, Samah B, Dormont D, Gras G (2006) Characterization of human monocyte-derived microglia-like cells. Glia 54:183-192 (Pubitemid 44230855)
    • (2006) GLIA , vol.54 , Issue.3 , pp. 183-192
    • Leone, C.1    Le Pavec, G.2    Meme, W.3    Porcheray, F.4    Samah, B.5    Dormont, D.6    Gras, G.7
  • 53
    • 33845648588 scopus 로고    scopus 로고
    • Suppression of microglial inflammatory activity by myelin phagocytosis: Role of p47-PHOX-mediated generation of reactive oxygen species
    • DOI 10.1523/JNEUROSCI.2531-06.2006
    • Liu Y, Hao W, Letiembre M, Walter S, Kulanga M, Neumann H, Fassbender K (2006) Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species. J Neurosci 26:12904-12913 (Pubitemid 44954610)
    • (2006) Journal of Neuroscience , vol.26 , Issue.50 , pp. 12904-12913
    • Liu, Y.1    Hao, W.2    Letiembre, M.3    Walter, S.4    Kulanga, M.5    Neumann, H.6    Fassbender, K.7
  • 54
    • 67650152231 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase
    • Loane DJ, Stoica BA, Pajoohesh-Ganji A, Byrnes KR, Faden AI (2009) Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase. J Biol Chem 284:15629-15639
    • (2009) J Biol Chem , vol.284 , pp. 15629-15639
    • Loane, D.J.1    Stoica, B.A.2    Pajoohesh-Ganji, A.3    Byrnes, K.R.4    Faden, A.I.5
  • 55
    • 0034728639 scopus 로고    scopus 로고
    • Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy
    • DOI 10.1016/S0169-328X(00)00022-X, PII S0169328X0000022X
    • Lopez-Redondo F, Nakajima K, Honda S, Kohsaka S (2000) Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy. Brain Res Mol Brain Res 76:429-435 (Pubitemid 30179784)
    • (2000) Molecular Brain Research , vol.76 , Issue.2 , pp. 429-435
    • Lopez-Redondo, F.1    Nakajima, K.2    Honda, S.3    Kohsaka, S.4
  • 56
    • 0035500299 scopus 로고    scopus 로고
    • Microglial phagocytosis of apoptotic inflammatory T cells leads to down-regulation of microglial immune activation
    • Magnus T, Chan A, Grauer O, Toyka KV, Gold R (2001) Microglial phagocytosis of apoptotic inflammatory T cells leads to downregulation of microglial immune activation. J Immunol 167: 5004-5010 (Pubitemid 33009732)
    • (2001) Journal of Immunology , vol.167 , Issue.9 , pp. 5004-5010
    • Magnus, T.1    Chan, A.2    Grauer, O.3    Toyka, K.V.4    Gold, R.5
  • 57
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez-Hernandez A, Bell KP, Norenberg MD (1977) Glutamine synthetase: glial localization in brain. Science 195:1356-1358 (Pubitemid 8056735)
    • (1977) Science , vol.195 , Issue.4284 , pp. 1356-1358
    • Martinez Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 59
    • 19744380563 scopus 로고    scopus 로고
    • Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • DOI 10.1126/science.1110647
    • Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-1318 (Pubitemid 40746128)
    • (2005) Science , vol.308 , Issue.5726 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 60
    • 0018776955 scopus 로고
    • The distribution of glutamine synthetase in the rat central nervous system
    • Norenberg MD (1979) Distribution of glutamine synthetase in the rat central nervous system. J Histochem Cytochem 27:756-762 (Pubitemid 9187420)
    • (1979) Journal of Histochemistry and Cytochemistry , vol.27 , Issue.3 , pp. 756-762
    • Norenberg, M.D.1
  • 61
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • DOI 10.1016/0006-8993(79)90071-4
    • Norenberg MD, Martinez-Hernandez A (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res 161:303-310 (Pubitemid 9087410)
    • (1979) Brain Research , vol.161 , Issue.2 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 63
    • 21044434245 scopus 로고    scopus 로고
    • +-dependent glutamate transporter of murine astrocytes by inflammatory mediators
    • Okada K, Yamashita U, Tsuji S (2005) Modulation of Na(+)- dependent glutamate transporter of murine astrocytes by inflammatory mediators. J Uoeh 27:161-170 (Pubitemid 40874389)
    • (2005) Journal of UOEH , vol.27 , Issue.2 , pp. 161-170
    • Okada, K.1    Yamashita, U.2    Tsuji, S.3
  • 64
    • 0026544324 scopus 로고
    • Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
    • Ottersen OP, Zhang N, Walberg F (1992) Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience 46:519-534
    • (1992) Neuroscience , vol.46 , pp. 519-534
    • Ottersen, O.P.1    Zhang, N.2    Walberg, F.3
  • 65
    • 0033826013 scopus 로고    scopus 로고
    • Gp120-induced alterations of human astrocyte function: Na(+)/ H(+) exchange, K(+) conductance, and glutamate flux
    • Patton HK, Zhou ZH, Bubien JK, Benveniste EN, Benos DJ (2000) gp120-induced alterations of human astrocyte function: Na(+)/ H(+) exchange, K(+) conductance, and glutamate flux. Am J Physiol Cell Physiol 279:C700-C708
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Patton, H.K.1    Zh, Z.2    Bubien, J.K.3    Benveniste, E.N.4    Benos, D.J.5
  • 66
    • 0022387412 scopus 로고
    • Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain
    • DOI 10.1016/0306-4522(85)90215-5
    • Perry VH, Hume DA, Gordon S (1985) Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain. Neuroscience 15:313-326 (Pubitemid 16197076)
    • (1985) Neuroscience , vol.15 , Issue.2 , pp. 313-326
    • Perry, V.H.1    Hume, D.A.2    Gordon, S.3
  • 67
    • 20144381062 scopus 로고    scopus 로고
    • Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-α
    • DOI 10.1002/glia.20191
    • Persson M, Brantefjord M, Hansson E, Ronnback L (2005) Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha. Glia 51:111-120 (Pubitemid 41277345)
    • (2005) GLIA , vol.51 , Issue.2 , pp. 111-120
    • Persson, M.1    Brantefjord, M.2    Hansson, E.3    Ronnback, L.4
  • 68
    • 33747876324 scopus 로고    scopus 로고
    • Uptake, metabolism and distribution of organic and inorganic nitrogen sources by Pinus sylvestris
    • DOI 10.1093/jxb/erl028
    • Persson J, Gardestrom P, Nasholm T (2006) Uptake, metabolism and distribution of organic and inorganic nitrogen sources by Pinus sylvestris. J Exp Bot 57:2651-2659 (Pubitemid 44290297)
    • (2006) Journal of Experimental Botany , vol.57 , Issue.11 , pp. 2651-2659
    • Persson, J.1    Gardestrom, P.2    Nasholm, T.3
  • 69
    • 34648836756 scopus 로고    scopus 로고
    • Microglial GLT-1 is upregulated in response to herpes simplex virus infection to provide an antiviral defence via glutathione
    • DOI 10.1002/glia.20560
    • Persson M, Brantefjord M, Liljeqvist JA, Bergstrom T, Hansson E, Ronnback L (2007) Microglial GLT-1 is upregulated in response to herpes simplex virus infection to provide an antiviral defence via glutathione. Glia 55:1449-1458 (Pubitemid 47461160)
    • (2007) GLIA , vol.55 , Issue.14 , pp. 1449-1458
    • Persson, M.1    Brantefjord, M.2    Liljeqvist, J.-A.3    Bergstrom, T.4    Hansson, E.5    Ronnback, L.6
  • 71
    • 34848843543 scopus 로고    scopus 로고
    • Neurotransmitter receptors on microglia
    • DOI 10.1016/j.tins.2007.07.007, PII S0166223607002111
    • Pocock JM, Kettenmann H (2007) Neurotransmitter receptors on microglia. Trends Neurosci 30:527-535 (Pubitemid 47513237)
    • (2007) Trends in Neurosciences , vol.30 , Issue.10 , pp. 527-535
    • Pocock, J.M.1    Kettenmann, H.2
  • 72
    • 35148835215 scopus 로고    scopus 로고
    • CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells
    • DOI 10.1523/JNEUROSCI.1922-07.2007
    • Ponomarev ED, Maresz K, Tan Y, Dittel BN (2007) CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. J Neurosci 27:10714-10721 (Pubitemid 47535871)
    • (2007) Journal of Neuroscience , vol.27 , Issue.40 , pp. 10714-10721
    • Ponomarev, E.D.1    Maresz, K.2    Tan, Y.3    Dittel, B.N.4
  • 75
    • 26944453586 scopus 로고    scopus 로고
    • Like cops on the beat: The active role of resting microglia
    • DOI 10.1016/j.tins.2005.09.001, PII S0166223605002420
    • Raivich G (2005) Like cops on the beat: the active role of resting microglia. Trends Neurosci 28:571-573 (Pubitemid 41476686)
    • (2005) Trends in Neurosciences , vol.28 , Issue.11 , pp. 571-573
    • Raivich, G.1
  • 76
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: Unique stimuli, specialized responses
    • Ransohoff RM, Perry VH (2009) Microglial physiology: unique stimuli, specialized responses. Annu Rev Immunol 27:119-145
    • (2009) Annu Rev Immunol , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 77
    • 0030973631 scopus 로고    scopus 로고
    • The glutathione level of retinal Muller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate
    • Reichelt W, Stabel-Burow J, Pannicke T, Weichert H, Heinemann U (1997) The glutathione level of retinal Muller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate. Neuroscience 77:1213-1224
    • (1997) Neuroscience , vol.77 , pp. 1213-1224
    • Reichelt, W.1    Stabel-Burow, J.2    Pannicke, T.3    Weichert, H.4    Heinemann, U.5
  • 78
    • 0017622252 scopus 로고
    • Muller cell localisation of glutamine synthetase in rat retina
    • Riepe RE, Norenburg MD (1977) Muller cell localisation of glutamine synthetase in rat retina. Nature 268:654-655 (Pubitemid 8227862)
    • (1977) Nature , vol.268 , Issue.5621 , pp. 654-655
    • Riepe, R.E.1    Norenburg, M.D.2
  • 82
    • 0021125414 scopus 로고
    • Synaptic release of excitatory amino acid neurotransmitter mediates axonic neuronal death
    • Rothman S (1984) Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J Neurosci 4:1884-1891 (Pubitemid 14055543)
    • (1984) Journal of Neuroscience , vol.4 , Issue.7 , pp. 1884-1891
    • Rothman, S.1
  • 83
    • 0021880922 scopus 로고
    • The neurotoxicity of excitatory amino acids is produced by passive chloride influx
    • Rothman SM (1985) The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J Neurosci 5:1483-1489 (Pubitemid 15041463)
    • (1985) Journal of Neuroscience , vol.5 , Issue.6 , pp. 1483-1489
    • Rothman, S.M.1
  • 86
    • 8744257812 scopus 로고    scopus 로고
    • Endothelins negatively regulate glial glutamate transporter expression
    • Rozyczka J, Figiel M, Engele J (2004) Endothelins negatively regulate glial glutamate transporter expression. Brain Pathol 14:406-414 (Pubitemid 39524970)
    • (2004) Brain Pathology , vol.14 , Issue.4 , pp. 406-414
    • Rozyczka, J.1    Figiel, M.2    Engele, J.3
  • 87
    • 0028675515 scopus 로고
    • Blood monocytes and spleen macrophages differentiate into microglialike cells on monolayers of astrocytes: Membrane currents
    • Schmidtmayer J, Jacobsen C, Miksch G, Sievers J (1994) Blood monocytes and spleen macrophages differentiate into microglialike cells on monolayers of astrocytes: membrane currents. Glia 12:259-267
    • (1994) Glia , vol.12 , pp. 259-267
    • Schmidtmayer, J.1    Jacobsen, C.2    Miksch, G.3    Sievers, J.4
  • 88
    • 14844309321 scopus 로고    scopus 로고
    • Protective autoimmunity: Interferon-γ enables microglia to remove glutamate without evoking inflammatory mediators
    • DOI 10.1111/j.1471-4159.2004.02954.x
    • Shaked I, Tchoresh D, Gersner R, Meiri G, Mordechai S, Xiao X, Hart RP, Schwartz M (2005) Protective autoimmunity: interferon- gamma enables microglia to remove glutamate without evoking inflammatory mediators. J Neurochem 92:997-1009 (Pubitemid 40344291)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.5 , pp. 997-1009
    • Shaked, I.1    Tchoresh, D.2    Gersner, R.3    Meiri, G.4    Mordechai, S.5    Xiao, X.6    Hart, R.P.7    Schwartz, M.8
  • 90
    • 0028676161 scopus 로고
    • Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: Morphology
    • Sievers J, Parwaresch R, Wottge HU (1994) Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: morphology. Glia 12:245-258
    • (1994) Glia , vol.12 , pp. 245-258
    • Sievers, J.1    Parwaresch, R.2    Wottge, H.U.3
  • 91
    • 14844316278 scopus 로고    scopus 로고
    • Positive and negative regulation of EAAT2 by NF-κB: A role for N-myc in TNFα-controlled repression
    • DOI 10.1038/sj.emboj.7600555
    • Sitcheran R, Gupta P, Fisher PB, Baldwin AS (2005) Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. EMBO J 24:510-520 (Pubitemid 40343253)
    • (2005) EMBO Journal , vol.24 , Issue.3 , pp. 510-520
    • Sitcheran, R.1    Gupta, P.2    Fisher, P.B.3    Baldwin, A.S.4
  • 92
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein M, Keshav S, Harris N, Gordon S (1992) Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 176:287-292
    • (1992) J Exp Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 93
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(?)-dependent glutamate/ aspartate transporter from rat brain
    • Storck T, Schulte S, Hofmann K, Stoffel W (1992) Structure, expression, and functional analysis of a Na(?)-dependent glutamate/ aspartate transporter from rat brain. Proc Natl Acad Sci USA 89:10955-10959
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 94
    • 33747358360 scopus 로고    scopus 로고
    • Migratory fate and differentiation of blood monocyte subsets
    • Tacke F, Randolph GJ (2006) Migratory fate and differentiation of blood monocyte subsets. Immunobiology 211:609-618
    • (2006) Immunobiology , vol.211 , pp. 609-618
    • Tacke, F.1    Randolph, G.J.2
  • 95
    • 34247500821 scopus 로고    scopus 로고
    • TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis
    • Takahashi K, Prinz M, Stagi M, Chechneva O, Neumann H (2007) TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis. PLoS Med 4:e124
    • (2007) PLoS Med , vol.4
    • Takahashi, K.1    Prinz, M.2    Stagi, M.3    Chechneva, O.4    Neumann, H.5
  • 96
    • 0034648770 scopus 로고    scopus 로고
    • Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons
    • Takamori S, Rhee JS, Rosenmund C, Jahn R (2000) Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons. Nature 407:189-194
    • (2000) Nature , vol.407 , pp. 189-194
    • Takamori, S.1    Rhee, J.S.2    Rosenmund, C.3    Jahn, R.4
  • 97
    • 0027483397 scopus 로고
    • Expression cloning of a rat glutamate transporter
    • DOI 10.1016/0168-0102(93)90082-2
    • Tanaka K (1993) Expression cloning of a rat glutamate transporter. Neurosci Res 16:149-153 (Pubitemid 23111224)
    • (1993) Neuroscience Research , vol.16 , Issue.2 , pp. 149-153
    • Tanaka, K.1
  • 99
    • 0037444442 scopus 로고    scopus 로고
    • Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity
    • Taylor DL, Diemel LT, Pocock JM (2003) Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity. J Neurosci 23:2150-2160 (Pubitemid 36368903)
    • (2003) Journal of Neuroscience , vol.23 , Issue.6 , pp. 2150-2160
    • Taylor, D.L.1    Diemel, L.T.2    Pocock, J.M.3
  • 102
    • 0034846740 scopus 로고    scopus 로고
    • Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat
    • DOI 10.1002/glia.1082
    • van Landeghem FK, Stover JF, Bechmann I, Bruck W, Unterberg A, Buhrer C, von Deimling A (2001) Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat. Glia 35:167-179 (Pubitemid 32827760)
    • (2001) GLIA , vol.35 , Issue.3 , pp. 167-179
    • Van Landeghem, F.K.H.1    Stover, J.F.2    Bechmann, I.3    Brck, W.4    Unterberg, A.5    Bhrer, C.6    Von Deimling, A.7
  • 103
    • 0034635496 scopus 로고    scopus 로고
    • Cloning and functional identification of a neuronal glutamine transporter
    • DOI 10.1074/jbc.275.6.4049
    • Varoqui H, Zhu H, Yao D, Ming H, Erickson JD (2000) Cloning and functional identification of a neuronal glutamine transporter. J Biol Chem 275:4049-4054 (Pubitemid 30094634)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.6 , pp. 4049-4054
    • Varoqui, H.1    Zhu, H.2    Yao, D.3    Ming, H.4    Erickson, J.D.5
  • 105
    • 0030818670 scopus 로고    scopus 로고
    • HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid
    • DOI 10.1016/S0014-5793(97)00674-1, PII S0014579397006741
    • Vesce S, Bezzi P, Rossi D, Meldolesi J, Volterra A (1997) HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid. FEBS Lett 411:107-109 (Pubitemid 27298381)
    • (1997) FEBS Letters , vol.411 , Issue.1 , pp. 107-109
    • Vesce, S.1    Bezzi, P.2    Rossi, D.3    Meldolesi, J.4    Volterra, A.5
  • 106
    • 0037461719 scopus 로고    scopus 로고
    • Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex
    • DOI 10.1016/S0896-6273(02)01170-4
    • Voutsinos-Porche B, Bonvento G, Tanaka K, Steiner P, Welker E, Chatton JY, Magistretti PJ, Pellerin L (2003) Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex. Neuron 37:275-286 (Pubitemid 36143822)
    • (2003) Neuron , vol.37 , Issue.2 , pp. 275-286
    • Voutsinos-Porche, B.1    Bonvento, G.2    Tanaka, K.3    Steiner, P.4    Welker, E.5    Chatton, J.-Y.6    Magistretti, P.J.7    Pellerin, L.8


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