Platelet count/spleen diameter ratio for non-invasive diagnosis of oesophageal varices: Is it useful in compensated cirrhosis?

Digestive and Liver Disease

Volumn 44, Issue 6, 2012, Pages 504-507

  Mangone, Manuela ^a   Moretti, Alessandra ^a   Alivernini, Federica ^b   Papi, Claudio ^a   Orefice, Ruggero ^a   Dezi, Angelo ^a   Amadei, Emanuela ^a   Aratari, Annalisa ^a   Bianchi, Marco ^a   Tornatore, Valentina ^a   Koch, Maurizio ^a  

^a SAN FILIPPO NERI HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Compensated cirrhosis; Oesophageal varices; Platelet count spleen diameter ratio; Portal hypertension

Indexed keywords

ADULT; AGED; ARTICLE; CALCULATION; COHORT ANALYSIS; DIAGNOSTIC ACCURACY; ENDOSCOPY; ESOPHAGUS VARICES; FEMALE; HUMAN; HYPERTENSIVE GASTROPATHY; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NON INVASIVE PROCEDURE; PORTAL HYPERTENSION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SPLEEN SIZE; STOMACH DISEASE; THROMBOCYTE COUNT;

ADULT; AGED; AGED, 80 AND OVER; ESOPHAGEAL AND GASTRIC VARICES; ESOPHAGOSCOPY; FEMALE; GASTROSCOPY; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; ORGAN SIZE; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; ROC CURVE; SPLEEN;

EID: 84860228286     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2011.12.016     Document Type: Article

References (45)

1. Schepis F., Cammà C., Niceforo D., et al. Which patients should undergo endoscopic screening for oesophageal varices detection?. Hepatology 2001, 33:333-338.
2. D'Amico G., Luca A. Natural history. Clinical-haemodynamic correlations. Prediction of the risk of bleeding. Baillieres Clin Gastroenterol 1997, 11:243-256.
3. Sarangapani A., Shanmugam C., Kalyanasundaram M., et al. Noninvasive prediction of large esophageal varices in chronic liver disease patients. Saudi J Gastroenterol 2010, 16:38-42.
4. De Franchis R. Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2010, 53:762-768. on behalf of the Baveno V Faculty.
5. Thomopoulos K.C., Labropoulou-Karatza C., Mimidis K.P., et al. Non-invasive predictors of the presence of large oesophageal varices in patients with cirrhosis. Dig Liver Dis 2003, 35:473-478.
6. Berzigotti A., Gilabert R., Abraldes J.G., et al. Noninvasive prediction of clinically significant portal hypertension and esophageal varices in patients with compensated liver cirrhosis. Am J Gastroenterol 2008, 103:1159-1167.
7. Zein C.O., Lindor K.D., Angulo P. Prevalence and predictors of oesophageal varices in patients with primary sclerosing cholangitis. Hepatology 2004, 39:204-210.
8. Pilette C., Oberti F., Aubè C., et al. Non-invasive diagnosis of esophageal varices in chronic liver disease. J Hepatol 1999, 31:867-873.
9. Zaman A., Becker T., Lapidus J., et al. Risk factors for the presence of varices in cirrhotic patients without history of variceal hemorrhage. Arch Int Med 2001, 161:2564-2570.
10. Sharma S.K., Aggarwal R. Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters. J Gastroenterol Hepatol 2007, 22:1909-1915.
11. Ng F.H., Wong S.Y., Loo C.K., et al. Prediction of oesophagogastric varices in patients with liver cirrhosis. J Gastroenterol Hepatol 1999, 14:785-790.
12. Burton J.R., Liangpunsakul S., Lapidus J., et al. Validation of a multivariate model predicting presence and size of varices. J Clin Gastroenterol 2007, 41:609-615.
13. Thabut D., Trabut J.B., Massard J., et al. Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study. Liver Int 2006, 26:271-278.
14. Cottone M., D'Amico G., Maringhini A., et al. Predictive value of ultrasonography in the screening of non-ascitic cirrhotic patients with large varices. J Ultrasound Med 1986, 5:189-192.
15. Madhotra R., Mulcahy H.E., Willner I., et al. Prediction of oesophageal varices in patients with cirrhosis. J Clin Gastroenterol 2002, 34:81-85.
16. Giannini E., Botta F., Borro P., et al. Platelet count/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis. Gut 2003, 52:1200-1205.
17. Giannini E.G., Botta F., Borro P., et al. Application of the platelet count/spleen diameter ratio to rule out the presence of oesophageal varices in patients with cirrhosis: a validation study based on follow up. Dig Liv Dis 2005, 37:779-785.
18. Giannini E., Zaman A., Kreil A., et al. Platelet count/spleen diameter ratio for the noninvasive diagnosis of esophageal varices: results of a multicenter, prospective, validation study. Am J Gastroenterol 2006, 101:2511-2519.
19. Kazemi F., Kettaneh A., N'kontchou G., et al. Liver stiffness measurement selects patients with cirrhosis at risk of bearing large oesophageal varices. J Hepatol 2006, 45:230-235.
20. Vizzutti F., Arena U., Romanelli R.G., et al. Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis. Hepatology 2007, 45:1290-1297.
21. Perri R.E., Chiorean M.V., Fidler J.L., et al. A prospective evaluation of computerized tomographic (CT) scanning as a screening modality for esophageal varices. Hepatology 2008, 47:1587-1594.
22. Kim Y.J., Raman S.S., Yu N.C., et al. Oesophageal varices in cirrhotic patients: evaluation with liver CT. AJR 2007, 188:139-144.
23. Kim S.H., Kim Y.J., Lee J.M., et al. Oesophageal varices in patients with cirrhosis: multidetector CT esophagography-comparison with endoscopy. Radiology 2007, 242:759-768.
24. Pena L.R., Cox T., Koch A.G., et al. Study comparing oesophageal capsule endoscopy versus EGD in the detection of varices. Dig Liver Dis 2008, 40:216-223.
25. De Franchis R., Eisen G.M., Laine L., et al. Oesophageal capsule endoscopy for screening and surveillance of oesophageal varices in patients with portal hypertension. Hepatology 2008, 47:1595-1603.
26. Eisen G., Eliakim R., Zaman A., et al. The accuracy of PillCam ESO capsule endoscopy versus conventional upper endoscopy for the diagnosis of oesophageal varices: a prospective three-center pilot study. Endoscopy 2006, 38:31-35.
27. Lapalus M.G., Dumortier J., Fumex F., et al. Esophageal capsule endoscopy versus esophagogastroduodenoscopy for evaluating portal hypertension: a prospective comparative study of performance and tolerance. Endoscopy 2006, 38:36-41.
28. Schwarzenberger E., Meyer T., Golla V., et al. Utilization of platelet count spleen diameter ratio in predicting the presence of esophageal varices in patients with cirrhosis. J Clin Gastroenterol 2010, 44:146-150.
29. Agha A., Anwar E., Bashir K., et al. External validation of the platelet count/spleen diameter ratio for the diagnosis of esophageal varices in hepatitis C virus-related cirrhosis. Dig Dis Sci 2009, 54:654-660.
30. Sen S., Griffiths W.J.H. Non-invasive prediction of oesophageal varices in cirrhosis. World J Gastroenterol 2008, 14:2454-2455.
31. Baig W.W., Nagaraja M.V., Varma M., et al. Platelet count to spleen diameter ratio for the diagnosis of esophageal varices. Is it feasible?. Can J Gastroenterol 2008, 22:825-828.
32. Barrera F., Riquelme A., Soza A., et al. Platelet count/spleen diameter ratio for non-invasive prediction of high risk esophageal varices in cirrhotic patients. Ann Hepatol 2009, 8:325-330.
33. Hong W.D., Zhu H.Q., Huang Z.M., et al. Predictors of esophageal varices in patients with HBV-related cirrhosis: a retrospective study. BMC Gastroenterol 2009, 9:1-7.
34. Barikbin R., Hekmatnia A., Omidifar N., et al. Prediction severity of esophageal varices: a new cut-off point for platelet count/spleen diameter ratio. Minerva Gastro Dietol 2010, 56:1-6.
35. Zambam de Mattos A., Alves de Mattos A. Platelet count/spleen diameter ratio as a predictor of esophageal varices in cirrhotic patients. Ann Hepatol 2010, 9:302-304.
36. Wai C.T., Greeson J.K., Fontana R.J., et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003, 38:518-526.
37. Gaiani S., Gramantieri L., Venturoli N., et al. What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy. J Hepatol 1997, 27:979-985.
38. Aubè C., Oberti F., Korali N., et al. Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis. J Hepatol 1999, 30:472-478.
39. Knodell R.G., Ishak K.G., Black W.C., et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981, 1:431-435.
40. Ishak K., Baptista A., Bianchi L., et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995, 22:696-699.
41. Scheuer P.J. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 1991, 13:372-374.
42. Bedossa P., Poynard T. An algorithm for the grading of activity in chronic hepatitis C. Hepatology 1996, 24:289-293. for the Metavir Cooperative Study Group.
43. De Franchis R. The North Italian Endoscopic Club for the study and treatment of esophageal varices. N Engl J Med 1988, 319:983-989.
44. McCormack T.T., Sims J., Eyre-Brook I., et al. Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy. Gut 1985, 26:1226-1232.
45. Mattos A.Z., Mattos A.A., Vianna F.F., Musskopf M.I., Pereira-Lima J.C., Maciel A.C. Platelet count/spleen diameter ratio: analysis of its capacity as a predictor of the existence of esophageal varices. Arq Gastroenterol 2010, 47:275-278.