Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning

Optics Express

Volumn 20, Issue 8, 2012, Pages 8939-8948

  Cheng, Li Chung ^a   Chang, Chia Yuan ^a   Lin, Chun Yu ^a   Cho, Keng Chi ^a   Yen, Wei Chung ^b   Chang, Nan Shan ^a   Xu, Chris ^c   Dong, Chen Yuan ^d   Chen, Shean Jen ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c Cornell University   (United States)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BROWNIAN MOVEMENT; EXCITED STATES; FOCUSING;

A-FRAMES; AXIAL RESOLUTIONS; BIO-IMAGING; FS PULSE; HIGH RESOLUTION; KEY FEATURE; MICROBEADS; MULTI-PHOTON MICROSCOPY; MULTIPHOTON EXCITATION; MULTIPHOTONS; OPTICAL SECTIONING; PEAK POWER; REPETITION RATE; SECOND HARMONICS; SPATIAL RESOLUTION; SPATIOTEMPORAL FOCUSING; ULTRA-FAST; WIDE-FIELD;

MICROSCOPES;

COLLAGEN; FLUORESCENT DYE; MICROSPHERE;

ANIMAL; ARTICLE; BLEACHING; CHEMISTRY; CHICKEN; EQUIPMENT DESIGN; HISTOLOGY; INSTRUMENTATION; LIGHT RELATED PHENOMENA; METHODOLOGY; MOTION; MULTIPHOTON MICROSCOPY; STATISTICS; TENDON;

ANIMALS; CHICKENS; COLLAGEN; EQUIPMENT DESIGN; FLUORESCENT DYES; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MICROSPHERES; MOTION; OPTICAL PHENOMENA; PHOTOBLEACHING; TENDONS;

EID: 84860210237     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.20.008939     Document Type: Article

References (34)

1. W. R. Zipfel, R. M. Williams, and W. W. Webb, "Nonlinear magic: multiphoton microscopy in the biosciences," Nat. Biotechnol. 21(11), 1369-1377 (2003). (Pubitemid 37356624)
2. I. Freund and M. Deutsch, "Second-harmonic microscopy of biological tissue," Opt. Lett. 11(2), 94-96 (1986).
3. G. J. Brakenhoff, J. Squier, T. Norris, A. C. Bliton, M. H. Wade, and B. Athey, "Real-time two-photon confocal microscopy using a femtosecond, amplified Ti:sapphire system," J. Microsc. 181(3), 253-259 (1996). (Pubitemid 26124656)
4. A. H. Buist, M. Müller, J. Squier, and G. J. Brakenhoff, "Real time two-photon absorption microscopy using multipoint excitation," J. Microsc. 192(2), 217-226 (1998). (Pubitemid 28539626)
5. J. Bewersdorf, R. Pick, and S. W. Hell, "Multifocal multiphoton microscopy," Opt. Lett. 23(9), 655-657 (1998). (Pubitemid 128590668)
6. D. Oron, E. Tal, and Y. Silberberg, "Scanningless depth-resolved microscopy," Opt. Express 13(5), 1468-1476 (2005). (Pubitemid 40548703)
7. E. Tal, D. Oron, and Y. Silberberg, "Improved depth resolution in video-rate line-scanning multiphoton microscopy using temporal focusing," Opt. Lett. 30(13), 1686-1688 (2005). (Pubitemid 40972041)
8. M. E. Durst, G. Zhu, and C. Xu, "Simultaneous spatial and temporal focusing in nonlinear microscopy," Opt. Commun. 281(7), 1796-1805 (2008). (Pubitemid 351274126)
9. A. Vaziri, J. Tang, H. Shroff, and C. V. Shank, "Multilayer three-dimensional super resolution imaging of thick biological samples," Proc. Natl. Acad. Sci. U.S.A. 105(51), 20221-20226 (2008).
10. A. Vaziri and C. V. Shank, "Ultrafast widefield optical sectioning microscopy by multifocal temporal focusing," Opt. Express 18(19), 19645-19655 (2010).
11. E. Papagiakoumou, F. Anselmi, A. Bègue, V. de Sars, J. Glückstad, E. Y. Isacoff, and V. Emiliani, "Scanless two-photon excitation of channelrhodopsin-2," Nat. Methods 7(10), 848-854 (2010).
12. O. D. Therrien, B. Aubé, S. Pagès, P. D. Koninck, and D. Côté, "Wide-field multiphoton imaging of cellular dynamics in thick tissue by temporal focusing and patterned illumination," Biomed. Opt. Express 2(3), 696-704 (2011).
13. K. H. Kim, C. Buehler, and P. T. C. So, "High-speed, two-photon scanning microscope," Appl. Opt. 38(28), 6004-6009 (1999). (Pubitemid 129569777)
14. A. Egner and S. W. Hell, "Time multiplexing and parallelization in multifocal multiphoton microscopy," J. Opt. Soc. Am. A 17(7), 1192-1201 (2000).
15. P. J. Keller and E. H. K. Stelzer, "Quantitative in vivo imaging of entire embryos with digital scanned laser light sheet fluorescence microscopy," Curr. Opin. Neurobiol. 18(6), 624-632 (2008).
16. J. Vermot, S. E. Fraser, and M. Liebling, "Fast fluorescence microscopy for imaging the dynamics of embryonic development," HFSP J 2(3), 143-155 (2008).
17. J. R. Lakowicz, Principles of Fluorescence Spectroscopy (Springer, 2006).
18. A. Van Orden, N. P. Machara, P. M. Goodwin, and R. A. Keller, "Single-molecule identification in flowing sample streams by fluorescence burst size and intraburst fluorescence decay rate," Anal. Chem. 70(7), 1444-1451 (1998).
19. H. Dana and S. Shoham, "Numerical evaluation of temporal focusing characteristics in transparent and scattering media," Opt. Express 19(6), 4937-4948 (2011).
20. R. M. Mazo, Brownian Motion: Fluctuations, Dynamics, and Applications (Oxford University Press, 2009).
21. T. A. Theodossiou, C. Thrasivoulou, C. Ekwobi, and D. L. Becker, "Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections," Biophys. J. 91(12), 4665-4677 (2006). (Pubitemid 44904251)
22. T.-M. Liu, M.-C. Chan, I.-H. Chen, S. H. Chia, and C.-K. Sun, "Miniaturized multiphoton microscope with a 24Hz frame-rate," Opt. Express 16(14), 10501-10506 (2008).
23. D. Oron and Y. Silberberg, "Harmonic generation with temporally focused ultrashort pulses," J. Opt. Soc. Am. B 22(12), 2660-2663 (2005). (Pubitemid 43104065)
24. D. Oron and Y. Silberberg, "Third-harmonic generation with cylindrical Gaussian beams," J. Opt. Soc. Am. B 21(11), 1964-1968 (2004).
25. E. Papagiakoumou, A. Bègue, O. Schwartz, D. Oron, and V. Emiliani, "Shaped two-photon excitation deep inside scattering tissue," submitted for publication.
26. C.-Y. Chung, K.-C. Cho, C.-C. Chang, C. H. Lin, W. C. Yen, and S. J. Chen, "Adaptive-optics system with liquid-crystal phase-shift interferometer," Appl. Opt. 45(15), 3409-3414 (2006). (Pubitemid 44021510)
27. M. A. A. Neil, R. Jükaitis, and T. Wilson, "Method of obtaining optical sectioning by using structured light in a conventional microscope," Opt. Lett. 22(24), 1905-1907 (1997). (Pubitemid 127598999)
28. T. Wilson, M. A. A. Neil, and R. Jükaitis, "Real-time three-dimensional imaging of macroscopic structures," J. Microsc. 191(2), 116-118 (1998). (Pubitemid 28378435)
29. S. T. Hess, T. P. Girirajan, and M. D. Mason, "Ultra-high resolution imaging by fluorescence photoactivation localization microscopy," Biophys. J. 91(11), 4258-4272 (2006). (Pubitemid 44887284)
30. E. Betzig, G. H. Patterson, R. Sougrat, O. W. Lindwasser, S. Olenych, J. S. Bonifacino, M. W. Davidson, J. Lippincott-Schwartz, and H. F. Hess, "Imaging intracellular fluorescent proteins at nanometer resolution," Science 313(5793), 1642-1645 (2006). (Pubitemid 44414039)
31. M. J. Rust, M. Bates, and X. Zhuang, "Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)," Nat. Methods 3(10), 793-796 (2006).
32. D. Lim, K. K. Chu, and J. Mertz, "Wide-field fluorescence sectioning with hybrid speckle and uniform-illumination microscopy," Opt. Lett. 33(16), 1819-1821 (2008).
33. D. Kim and P. T. So, "High-throughput three-dimensional lithographic microfabrication," Opt. Lett. 35(10), 1602-1604 (2010).
34. Y.-C. Li, L.-C. Cheng, C.-H. Lien, C.-Y. Chang, N.-S. Chang, P. J. Campagnola, C. Y. Dong, and S.-J. Chen, "Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned generation," submitted for publication.