Evidence in favor of a severely impaired net intestinal calcium absorption in patients with (early-stage) chronic kidney disease

American Journal of Nephrology

Volumn 35, Issue 5, 2012, Pages 434-441

  Viaene, L ^a   Meijers, B K I ^a   Vanrenterghem, Y ^a   Evenepoel, P ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Chronic kidney disease; Intestinal calcium absorption; Phosphorus

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; PARATHYROID HORMONE; PHOSPHORUS;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CALCIUM ABSORPTION; CALCIUM BALANCE; CALCIUM EXCRETION; CALCIUM URINE LEVEL; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; INTESTINE ABSORPTION; MAJOR CLINICAL STUDY; MALE; MINERAL METABOLISM; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PRIORITY JOURNAL; URINALYSIS; VITAMIN BLOOD LEVEL;

ADULT; AGED; BELGIUM; CALCIFEDIOL; CALCITRIOL; CALCIUM, DIETARY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INTESTINAL ABSORPTION; MALE; MIDDLE AGED; PARATHYROID HORMONE; PHOSPHORUS; RENAL INSUFFICIENCY, CHRONIC;

EID: 84860182033     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000338299     Document Type: Article

References (47)

1. Quarles D: Endocrine functions of bone in mineral metabolism regulation. J Clin Invest 2008; 118:3820-3828.
2. Shimada T, Hasegawa H, Yamazaki Y, Muto T, Hino R, Takeuchi Y, Fujita T, Nakahara K, Fukumoto S, Yamashita T: FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. Bone Miner Res 2004; 19: 429-435. (Pubitemid 38787398)
3. Renkema KY, Alexander RT, Bindels RJ, Hoenderop JG: Calcium and phosphate homeo-stasis: concerted interplay of new regulators. Ann Med 2008; 40: 82-91. (Pubitemid 351640643)
4. Gueguen L, Pointillart A: The bioavailability of dieta r y calcium. J Am Col l Nutr 200 0; 19: 119S-136S.
5. Mountokalakis TH, Singhellakis PN, Ale-vizaki CC, Virvidakis K, Ikkos DG: Relationship between degree of renal failure and impairment of intestinal calcium absorption. Nephron 1976; 16:20-30.
6. Recker RR, Saville PD: Calcium absorption in renal failure: its relationship to blood urea nitrogen, dietary calcium intake, time on dialysis, and other variables. J Lab Clin Med 1971; 78:380-388.
7. Coburn JW, Koppel MH, Brickman AS, Massry SG: Study of intestinal absorption of calcium in patients with renal failure. Kidney Int 1973; 3: 264-272.
8. Malluche HH, Werner E, Ritz E: Intestinal absorption of calcium and whole-body calcium retention in incipient and advanced renal failure. Miner Electrolyte Metab 1978; 1: 263-270. (Pubitemid 9020248)
9. Heuser A, Eisenhauer A: A pilot study on the use of natural calcium isotope (44Ca/40Ca) fractionation in urine as a proxy for the human body calcium balance. Bone 2010; 46: 889-896.
10. Parfitt AM: Misconceptions IV-the hypo-phosphatemia of primary hyperparathy-roidism is the result of renal phosphate wasting. Bone 2004; 35: 345-347. (Pubitemid 38953178)
11. Bouillon R, Van Herck E, Jans I, Tan BK, Van Baelen H, De Moor P: Two direct (nonchro-matographic) assays for 25-hydroxyvitamin D. Clin Chem 1984; 30:1731-1736. (Pubitemid 15116038)
12. Bouillon R, De Moor P, Baggiolini EG, Us-kokovic MR: A radioimmunoassay for 1, 25-dihydroxycholecalciferol. Clin Chem 1980; 26: 562-567.
13. Bouillon R, Coopmans W, Degroote DE, Ra-doux D, Eliard PH: Immunoradiometric assay of parathyrin with polyclonal and monoclonal region-specific antibodies. Clin Chem 1990; 36:271-276.
14. National Kidney Foundation: K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis 2003; 42:S1-S201.
15. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D: A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. A nn Intern Med 1999; 130: 461-470. (Pubitemid 29135798)
16. Craver L, Marco MP, Martinez I, Rue M, Borras M, Martin ML, Sarro F, Valdivielso JM, Fernandez E: Mineral metabolism parameters throughout chronic kidney disease stages 1-5-achievement of K/DOQI target ranges. Nephrol Dial Transplant 2007; 22: 1171-1176. (Pubitemid 46523434)
17. Loghman-Adham M: Renal and intestinal Pi transport adaptation to low phosphorus diet in uremic rats. J Am Soc Nephrol 1993; 3: 1930-1937.
18. Marks J, Debnam ES, Unwin RJ: Phosphate homeostasis and the renal-gastrointestinal axis. Am J Physiol Renal Physiol 2010; 299:F285-F296.
19. Isakova T, Anderson CA, Leonard MB, Xie D, Gutierrez OM, Rosen LK, Theurer J, Bellovich K, Steigerwalt SP, Tang I, Anderson AH, Townsend RR, He J, Feldman HI, Wolf M: Diuretics, calciuria and secondary hyper-parathyroidism in the Chronic Renal Insufficiency Cohort. Nephrol Dial Transplant 2011; 26: 1258-1265.
20. Coburn JW, Maung HM, Elangovan L, Germain MJ, Lindberg JS, Sprague SM, Williams ME, Bishop CW: Doxercalciferol safely suppresses PTH levels in patients with secondary hyperparathyroidism associated with chronic kidney disease stages 3 and 4. Am J Kidney Dis 2004; 43:877-890. (Pubitemid 38529626)
21. Taylor EN, Curhan GC: Demographic, dietary, and urinary factors and 24-h urinary calcium excretion. Clin J Am Soc Nephrol 2009; 4: 1980-1987.
22. Oliveira RB, Cancela ALE, Graciolli FG, Dos Reis LM, Draibe SA, Cuppari L, Carvalho AB, Jorgetti V, Canziani ME, Moyses RMA: Early control of PTH and FGF23 in normo-phosphatemic CKD patients: a new target in CKD-MBD therapy? Clin J Am Soc Nephrol 2010; 5:286-291.
23. Isakova T, Gutierrez OM, Smith K, Epstein M, Keating LK, Juppner H, Wolf M: Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease. Nephrol Dial Transplant 2011; 26: 584-591.
24. Drueke T, Lacour B: Disorders of calcium, phosphate, and magnesium metabolism; in Feehally J, Floege J, Johnson RJ (eds): Comprehensive Clinical Nephrology. Philadelphia, Mosby, 2007, pp 123-140.
25. Tessitore N, Venturi A, Adami S, Roncari C, Rugiu C, Corgnati A, Bonucci E, Maschio G: Relationship between serum vitamin D metabolites and dietary intake of phosphate in patients with early renal failure. Miner Electrolyte Metab 1987; 13: 38-44. (Pubitemid 17051973)
26. O'Brien KO, Abrams SA, Stuff JE, Liang LK, Welch TR: Variables related to urinary calcium excretion in young girls. J Pediatr Gas-troenterol Nutr 1996; 23: 8-12. (Pubitemid 26231025)
27. Heinrich T, Heidt H, Hafner V, Schmidt-Gayk H, Jenetzky E, Walter-Sack I, Mikus G, Bommer J: Calcium load during administration of calcium carbonate or sevelamer in individuals with normal renal function. Nephrol Dia l Transplant 2008; 23: 2861-2867.
28. Bronner F: Nutrient bioavailability, with special reference to calcium. J Nutr 1993; 123: 797-802. (Pubitemid 23148815)
29. Heaney RP, Dowell MS, Hale CA, Bendich A: Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 2003; 22:142-146. (Pubitemid 36417827)
30. Knapp EL: Factors influencing the urinary excretion of calcium. I. In normal persons. J Clin Invest 1947; 26: 18 2-2 0 2.
31. Teucher B, Dainty JR, Spinks CA, Majsak-Newman G, Berry DJ, Hoogewerff JA, Foxall RJ, Jakobsen J, Cashman KD, Flynn A, Fair-weather-Tait SJ: Sodium and bone health: impact of moderately high and low salt intakes on calcium metabolism in postmeno-pausal women. J Bone Miner Res 2008; 23: 1477-1485.
32. Hill K, Martin B, Moe SM, McCabe GP, Weaver CM, Peacock M: Effect of calcium carbonate supplement on phosphate balance and homeostasis in patients with stage 3 and 4 chronic kidney disease. ASN 2011.
33. Spiegel DM, Moore RH: Positive calcium balance in CKD. ASN 2010.
34. 2-vitamin D concentrations and net intestinal calcium, phosphate, and magnesium absorption in humans. Am J Clin Nutr 1979; 32:2052-2060. (Pubitemid 10244801)
35. Wasserman RH: Vitamin D and the dual processes of intestinal calcium absorption. J Nutr 2004; 134: 3137-3139. (Pubitemid 39470097)
36. Kutuzova GD, DeLuca HF: Gene expression profiles in rat intestine identify pathways for 1, 25-dihydroxyvitamin D(3) stimulated calcium absorption and clarify its immuno-modulatory properties. Arch Biochem Bio-phys 2004; 432:152-166. (Pubitemid 39470012)
37. Heaney RP: Vitamin D endocrine physiology. J Bone Miner Res 2007; 22(suppl 2):V25-V27. (Pubitemid 351304644)
38. Kinyamu HK, Gallagher JC, Prahl JM, De-Luca HF, Petranick KM, Lanspa SJ: Association between intestinal vitamin D receptor, calcium absorption, and serum 1, 25 dihy-droxyvitamin D in normal young and elderly women. J Bone Miner Res 1997; 12:922-928. (Pubitemid 27225002)
39. Wood RJ, Fleet JC, Cashman K, Bruns ME, DeLuca HF: Intestinal calcium absorption in t he aged rat: ev idence of i ntestina l resista nce to 1, 25(OH)2 vitamin D. Endocrinology 1998; 139: 3843-3848. (Pubitemid 28512266)
40. Sheikh MS, Schiller LR, Fordtran JS: In vivo intestinal absorption of calcium in humans. Miner Electroly te Metab 1990; 16: 130-146. (Pubitemid 20336857)
41. Patel SR, Ke H-Q, Vanholder R, Koenig RJ, Hsu CH: Inhibition of calcitriol receptor binding to vitamin D response elements by uremic toxins. J Clin Invest 1995; 96:50-59.
42. Bammens B, Verbeke K, Vanrenterghem Y, Evenepoel P: Evidence for impaired assimilation of protein in chronic renal failure. Kidney Int 2003; 64:2196-2203. (Pubitemid 37449555)
43. Muto S, Murayama N, Asano Y, Hosoda S, Miyata M: Hypergastrinemia and achlorhy-dria in chronic renal failure. Nephron 1985; 40:143-148. (Pubitemid 15064562)
44. Yilmaz MI, Saglam M, Caglar K, Cakir E, Sonmez A, Ozgurtas T, Aydin A, Eyileten T, Ozcan O, Acikel C, Tasar M, Genctoy G, Er-bil K, Vural A, Zoccali C: The determinants of endothelial dysfunction in CKD: oxida-tive stress and asymmetric dimethylargi-nine. Am J Kidney Dis 2006; 47:42-50. (Pubitemid 41828265)
45. Ebert R, Jovanovic M, Ulmer M, Schneider D, Meissner-Weigl J, Adamski J, Jakob F: Down-regulation by nuclear factor kappaB of human 25-hydroxyvitamin D3 1alpha-hy-droxylase promoter. Mol Endocrinol 2004; 18: 2440-2450. (Pubitemid 39335979)
46. Block GA, Raggi P, Bellasi A, Kooienga L, Spiegel DM: Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int 2007; 71: 438-441.
47. Klawansky S, Komaroff E, Cavanaugh PF Jr, Mitchell DY, Gordon MJ, Connelly JE, Ross SD: Relationship between age, renal function and bone mineral density in the US population. Osteoporos Int 2003; 14:570-576. (Pubitemid 36975556)