Modulation of chromatin access during adipocyte differentiation

Nucleus

Volumn 3, Issue 1, 2012, Pages 12-15

  Mandrup, Susanne ^a   Hager, Gordon L ^b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Adipocyte differentiation; C EBPbeta; ChIP seq; Chromatin structure; DHS seq; DNase I hypersensitive sites; Hotspot

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; DNA BINDING PROTEIN; RETINOID X RECEPTOR; STAT5A PROTEIN;

ADIPOCYTE; ADIPOGENESIS; ARTICLE; CELL MATURATION; CELL PROLIFERATION; CHROMATIN; CHROMATIN STRUCTURE; EPIGENETICS; NONHUMAN;

EID: 84860168996     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.18928     Document Type: Article

References (10)

1. Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat Methods 2007; 4:651-657. PMID:17558387; http://dx.doi.org/10.1038/nmeth1068
2. Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 2008; 132:958-970. PMID:18358809; http://dx.doi.org/10.1016/j.cell.2008.01.018
3. Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, Megens E, et al. Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev 2008; 22:2953-2967. PMID:18981474; http://dx.doi.org/10.1101/gad.501108
4. Reddy TE, Pauli F, Sprouse RO, Neff NF, Newberry KM, Garabedian MJ, et al. Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. Genome Res 2009; 19:2163-2171. PMID:19801529; http://dx.doi.org/10.1101/gr.097022.109
5. John S, Sabo PJ, Thurman RE, Sung MH, Biddie SC, Johnson TA, et al. Chromatin accessibility predetermines glucocorticoid receptor binding patterns. Nat Genet 2011; 43:264-268. PMID:21258342; http://dx.doi.org/10.1038/ng.759
6. John S, Sabo PJ, Johnson TA, Sung MH, Biddie SC, Lightman SL, et al. Interaction of the glucocorticoid receptor with the global chromatin landscape. Mol Cell 2008; 29:611-624. PMID:18342607; http://dx.doi.org/10.1016/j.molcel.2008.02.010
7. Hesselberth JR, Zhang Z, Sabo PJ, Chen X, Sandstrom R, Reynolds AP, et al. Global mapping of protein- DNA interactions in vivo by digital genomic footprinting. Nat Methods 2009; 6:283-289. PMID:19305407; http://dx.doi.org/10.1038/nmeth.1313
8. Crawford GE, Holt IE, Whittle J, Webb BD, Tai D, Davis S, et al. Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res 2006; 16:123-131. PMID:16344561; http://dx.doi.org/10.1101/gr.4074106
9. Biddie SC, John S, Sabo PJ, Thurman RE, Johnson TA, Schiltz RL, et al. Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol Cell 2011; 43:145-155. PMID:21726817; http://dx.doi.org/10.1016/j.molcel.2011.06.016
10. Siersbæk R, Nielsen R, John S, Sung MH, Baek S, Loft A, et al. Adipogenic development is associated with extensive early remodeling of the chromatin landscape and establishment of transcription factor 'hotspots'. EMBO J 2011; 30:1459-1472. PMID:21427703; http://dx.doi.org/10.1038/emboj.2011.65