Crimp frequency is strongly correlated to myofibroblast density in the human anterior cruciate ligament and its autologous tendon grafts

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 20, Issue 5, 2012, Pages 889-895

  Weiss, Markus ^a   Unterhauser, Frank N ^b   Weiler, Andreas ^c  

^a Krankenhaus St Josef   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c Sporthopaedicum   (Germany)

Author keywords

smooth muscle actin; ACL; Crimp; Myofibroblast; Tendon

Indexed keywords

ACTIN;

ADULT; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; AUTOTRANSPLANTATION; CELL COUNT; CHEMISTRY; CYTOLOGY; FIBROBLAST; HUMAN; IMMUNOHISTOCHEMISTRY; MYOFIBROBLAST; PATELLA LIGAMENT; TENDON; TRANSPLANTATION;

ACTINS; ADULT; ANTERIOR CRUCIATE LIGAMENT; CELL COUNT; FIBROBLASTS; HUMANS; IMMUNOHISTOCHEMISTRY; MYOFIBROBLASTS; PATELLAR LIGAMENT; TENDONS; TRANSPLANTATION, AUTOLOGOUS; TRANSPLANTS;

EID: 84860142398     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-011-1644-4     Document Type: Article

References (40)

1. Adler K, Craighead J, Vallyathan N, Evans J (1981) Actin-containing cell in human pulmonary fibrosis. Am J Pathol 102: 427-437.
2. Baur P, Parks D (1983) The myofibroblast anchoring strand: the fibronectin connection in wound healing and the possible loci of collagen fibril assembly. J Trauma 23: 853-862.
3. Chen C-H, Chang C-H, Su C-I, Wang K-C, Liu H-T, Yu C-M, Wong C-B, Wang IC (2010) Arthroscopic single-bundle anterior cruciate ligament reconstruction with periosteum-enveloping hamstring tendon graft: clinical outcome at 2 to 7 years. Arthroscopy 26: 907-917.
4. Darby I, Skalli O, Gabbiani G (1990) Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest 63: 21-29.
5. Drogset JO, Straume LG, Bjorkmo I, Myhr G (2010) Autologous patellar tendon and quadrupled hamstring grafts in anterior cruciate ligament reconstruction: a prospective randomized multicenter review of different fixation methods. Knee Surg Sports Traumatol Arthrosc 18: 1085-1093.
6. Dustmann M, Schmidt T, Gangey I, Unterhauser FN, Weiler A, Scheffler SU (2008) The extracellular remodelling of free-soft-tissue autografts and allografts for reconstruction of the anterior cruciate ligament: a comparison study in a sheep model. Knee Surg Sports Traumatol Arthrosc 16: 360-369.
7. Eddy R, Petro J, Tomasek J (1988) Evidence of non-muscle nature of the myofibroblast of granulation tissue and hypertrophic scar. Am J Pathol 130: 252-260.
8. Estes J, Vande Berg J, Adzick N, McGillivray T, Desmouliere A, Gabbiani G (1994) Phenotypic and functional features of myofibroblasts in sheep fetal wounds. Differentiation 56: 173-181.
9. Faryniarz DA, Chaponnier C, Gabbiani G, Yannas IV, Spector M (1996) Myofibroblasts in the healing lapine medial collateral ligament: possible mechanisms of contraction. J Orthop Res 14: 228-237.
10. Frank C, Jackson D (1997) The science of reconstruction of the ACL. J Bone Jt Surg A 79: 1556-1576.
11. Gabbiani G, Hirschel BJ, Ryan GB, Statkov PR, Majno G (1972) Granulation tissue as a contractile organ. A study of structure and function. J Exp Med 135: 719-734.
12. Gabbiani G, Majno G (1972) Dupuytren's contracture: fibroblast contraction? An ultrastructural study. Am J Pathol 66: 131-146.
13. Hadjicostas PT, Soucacos PN, Paessler HH, Koleganova N, Berger I (2007) Morphologic and histologic comparison between the patella and hamstring tendons grafts: a descriptive and anatomic study. Arthroscopy 23: 751-756.
14. Harris AK, Stopak D, Wild P (1981) Fibroblast traction as a mechanism for collagen morphogenesis. Nature 290: 249-251.
15. Ippolito E, Natali P, Postachini F, Accini L, De Martino C (1977) Ultrastructural and immunohistochemical evidence of actin in tendon cells. Clin Orthop Relat Res 126: 282-284.
16. Ippolito E, Natali P, Postachini F, Accini L, De Martino C (1980) Morphological, immunochemical, and biochemical study of rabbit Achilles tendon at various ages. J Bone Jt Surg A 62: 583-598.
17. Janssen RP, van der Wijk J, Fiedler A, Schmidt T, Sala HA, Scheffler SU (2011) Remodelling of human hamstring autografts after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 19(8): 1299-1306. doi: 10. 1007/s00167-011-1419-y.
18. Lee JH, Bae DK, So SJ, Cho SM, Yoon KH (2010) Comparison of clinical results and second-look arthroscopy findings after arthroscopic anterior cruciate ligament reconstruction using 3 different types of grafts. Arthroscopy 26: 41-49.
19. Murray MM, Martin SD, Martin TL, Spector M (2000): Histological changes in the human anterior cruciate ligament after rupture. J Bone Jt Surg Am 82-A: 1387-1397.
20. Murray MM, Spector M (1999) Fibroblast distribution in the anteromedial bundle of the human anterior cruciate ligament: the presence of alpha-smooth muscle actin positive cells. J Orthop Res 17: 18-27.
21. Murray MM, Weiler A, Spindler KP (2004) Interspecies variation in the fibroblast distribution of the anterior cruciate ligament. Am J Sports Med 32: 1484-1491.
22. Nagle RB, Kneiser MR, Bulger RE, Benditt EP (1973) Induction of smooth muscle characteristics in renal interstitial fibroblasts during obstructive nephropathy. Lab Invest 29: 422-427.
23. Nha KW, Shetty GM, Ahn JH, Lee YS, Chae DJ, Nam HW, Lee DH (2010) Augmentation of autologous hamstring graft during anterior cruciate ligament reconstruction using the bone chip technique. Knee Surg Sports Traumatol Arthrosc 18: 89-91.
24. Oda D, Gown A, Vande Berg J, Stern R (1988) The fibroblast-like nature of myofibroblasts. Exp Mol Pathol 49: 316-329.
25. Radice F, Yanez R, Gutierrez V, Rosales J, Pinedo M, Coda S (2010) Comparison of magnetic resonance imaging findings in anterior cruciate ligament grafts with and without autologous platelet-derived growth factors. Arthroscopy 26: 50-57.
26. Rudolph R, McLure W, Woodward M (1979) Contractile fibroblasts in chronic alcoholic cirrhosis. Gastroenterology 76: 704-709.
27. Samuelsson K, Andersson D, Karlsson J (2009) Treatment of anterior cruciate ligament injuries with special reference to graft type and surgical technique: an assessment of randomized controlled trials. Arthroscopy 25: 1139-1174.
28. Sappino A, Schürch W, Gabbiani J (1990) Biology of disease-differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as markers of phenotypic modulations. Lab Invest 63: 144-161.
29. Schürch W, Seemeyer T, Gabbiani G (1998) The myofibroblast: a quarter century after its discovery. Am J Surg Pathol 22: 141-147.
30. Serini G, Gabbiani G (1999) Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res 250: 273-283.
31. Skalli O, Pelte MF, Peclet MC, Gabbiani G, Gugliotta P, Bussolati G, RavazzolaM OrciL (1989) Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes. J Histochem Cytochem 37: 315-321.
32. Skalli O, Ropraz P, Trzeciak BenzonanaG, Gillesen D, Gabbiani G (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 103: 2787-2796.
33. Skalli O, Schürch W, Seemayer T, Lagace R, Pittet B, Montandon D et al (1989) Myofibroblasts from diverse pathologic settings are heterogenous in their content of actin isoforms and intermediate filament proteins. Lab Invest 60: 275-285.
34. Stopak D, Harris A (1982) Connective tissue morphogenesis by fibroblast traction. I. Tissue culture observations. Dev Biol 90: 383-398.
35. Unterhauser F, Bail H, Höher J, Haas N, Weiler A (2003) Endoligamentous revascularisation of an anterior cruciate ligament graft. Clin Orthop Relat Res 414: 276-288.
36. Weiler A, Förster C, Hunt P, Falk R, Jung T, Unterhauser FN, Bergmann V, Schmidmeier G, Haas NP (2004) The influence of locally applied platelet-derived growth factor-BB on free tendon graft remodelling after anterior cruciate ligament reconstruction. Am J Sports Med 32: 881-891.
37. Weiler A, Unterhauser FN, Bail HJ, Huning M, Haas NP (2002) Alpha-smooth muscle actin is expressed by fibroblastic cells of the ovine anterior cruciate ligament and its free tendon graft during remodeling. J Orthop Res 20: 310-317.
38. Wen CY, Qin L, Lee KM, Wong MW, Chan KM (2010) Grafted tendon healing in tibial tunnel is inferior to healing in femoral tunnel after anterior cruciate ligament reconstruction: a histomorphometric study in rabbits. Arthroscopy 26: 58-66.
39. Yasuda K, Hayashi K (1997) Remodeling of tendon autograft in ligament reconstruction. In: Hayashi K, Kamiya A, Ono K (eds) Biomechanics: functional adaptation and remodeling. Springer, Heidelberg, pp 214-250.
40. Zamarra G, Fisher MB, Woo SL, Cerulli G (2010) Biomechanical evaluation of using one hamstrings tendon for ACL reconstruction: a human cadaveric study. Knee Surg Sports Traumatol Arthrosc 18: 11-19.