Does Heller's myotomy provide superior clinical outcome in comparison to botulinum toxin injection for treatment of achalasia?. Best evidence topic (BET)

International Journal of Surgery

Volumn 10, Issue 3, 2012, Pages 120-123

  Fovos, Athanasios ^a,b   Jarral, Omar ^a   Patel, Vanash ^a   Podas, Thrasyvoulos ^b   Spalding, Duncan ^a   Zacharakis, Emmanouil ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b St Luke's General Hospital   (Greece)

Author keywords

Achalasia; Botulinum toxin; Heller's myotomy; Pneumatic dilatation

Indexed keywords

BOTULINUM TOXIN;

BALLOON DILATATION; CARDIOESOPHAGOMYOTOMY; COMPARATIVE STUDY; ESOPHAGUS ACHALASIA; FOLLOW UP; GASTROESOPHAGEAL REFLUX; HUMAN; LOWER ESOPHAGUS SPHINCTER; PRIORITY JOURNAL; REVIEW; SURGICAL RISK; TREATMENT OUTCOME;

ANTI-DYSKINESIA AGENTS; BOTULINUM TOXINS; ESOPHAGEAL ACHALASIA; ESOPHAGUS; HUMANS; INJECTIONS, INTRAMUSCULAR; MUSCLE, SMOOTH; TREATMENT OUTCOME;

EID: 84860129715     PISSN: 17439191     EISSN: 17439159     Source Type: Journal    
DOI: 10.1016/j.ijsu.2012.01.008     Document Type: Review

References (7)

1. Dunning J., Prendergast B., Mackway-Jones K. Towards evidence-based medicine in cardiothoracic surgery: best BETS. Interact Cardiovasc Thorac Surg 2003, 2:405-409.
2. Zaninotto G., Annese V., Costantini M., Del Genio A., Costantino M., Epifani M., et al. Randomized controlled trial of botulinum toxin versus laparoscopic Heller myotomy for esophageal achalasia. Ann Surg 2004, 239(3):364-370.
3. Annese V., Bassotti G., Coccia D., Dinelli M., D'Onofrio V., Gatto G., et al. A multicenter randomised study of intrasphinteric botulinum toxin in patients with oesophageal achalasia. Gut 2000, 46:597-600.
4. Wang L., Li Y.M., Li L. Meta-analysis of randomized and controlled treatment trials for achalasia. Digest Dis Sci. 2009 Nov, 54(11):2303-2311.
5. Vela M.F., Richter J.E., Wachsberger D., Connor J., Rice T.W. Complexities of managing achalasia at a tertiary referral center: use of pneumatic dilatation, Heller myotomy, and botulinum toxin injection. Am J Gastroenterol 2004 Jun, 99(6):1029-1036.
6. Andrews C.N., Anvari M., Dobranowski J. Laparoscopic Heller's myotomy or botulinum toxin injection for management of esophageal achalasia. Patient choice and treatment outcomes. Surg Endosc 1999 Aug, 13(8):742-746.
7. Gutschow C.A., Töx U., Leers J., Schäfer H., Prenzel K.L., Hölscher A.H. Botox, dilation, or myotomy? Clinical outcome of interventional and surgical therapies for achalasia. Langenbecks Arch Surg 2010 Nov, 395(8):1093-1099.