Kinetics and mechanism of permanganate oxidation of clopidogrel hydrogen sulfate: An antiplatelet drug in acid perchlorate solutions

Industrial and Engineering Chemistry Research

Volumn 50, Issue 19, 2011, Pages 10962-10971

  Byadagi, Kirthi S ^a   Hosahalli, Rajeshwari V ^a   Nandibewoor, Sharanappa T ^a   Chimatadar, Shivamurti A ^a  

^a KARNATAK UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACID MEDIUM; ACTIVATION PARAMETER; ACTIVE SPECIES; BIOLOGICAL METABOLISM; CLOPIDOGREL; FIRST-ORDER; HYDROGEN SULFATE; ION CONCENTRATIONS; KINETICS AND MECHANISM; OXIDATION PRODUCTS; OXIDATION REACTIONS; PERCHLORATE SOLUTIONS; PERCHLORIC ACIDS; PERMANGANATE OXIDATION; RATE DETERMINING STEP; SPECTRAL STUDIES; THERMODYNAMIC QUANTITIES;

INORGANIC ACIDS; INORGANIC COMPOUNDS; IONIC STRENGTH; MANGANESE OXIDE; SPECTROSCOPIC ANALYSIS; STOICHIOMETRY;

OXIDATION;

EID: 84860125540     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie200164g     Document Type: Article

References (20)

1. Wiberg, K. B. Oxidation in Organic Chemistry; Academic Press: New York, 1965; Part A, pp 6, 57.
2. Naik, P. N.; Chimatadar, S. A.; Nandibewoor, S. T. Kinetics and Oxidation of Fluoroquinoline Antibacterial Agent, Norfloxacin, by Alkaline Permanganate: A Mechanistic Study. Ind. Eng. Chem. Res. 2009, 48, 2548-2555.
3. Day, M. C.; Selbin, J. Theoretical Inorganic Chemistry; Reinhold Publishing Corporation: New York, 1985; p 344.
4. Hassan, R. M. Kinetics and Mechanism of Oxidation of DL-α- Alanine by Permanganate Ion in Acid Perchlorate Media. Can. J. Chem. 1991, 69, 2018-2023.
5. Sen, P. K.; Saniyal, A.; Sen Gupta, K. K. Evidence of Protonation during the Oxidation of Some Aryl Alcohols by Permanganate in Perchloric Acid Medium and Mechanism of the Oxidation. Int. J. Chem. Kinet. 1995, 27, 379-389.
6. Clarke, T. A.; Waskell, L. A. The Metabolism of Clopidogrel Is Catalyzed by Human Cytochrome P450 3A and Is Inhibited by Atorvastatin. Drug Metab. Dispos. 2002, 31, 53-59.
7. Neubauer, H.; Krüger, J. C.; Lask, S.; Endres, H. G.; Pepinghege, F.; Engelhardt, A.; Bulut, D.; Mügge, A. Comparing the Antiplatelet Effect of Clopidogrel Hydrogen Sulfate and Clopidogrel Besylate: A Crossover Study. Clin. Res. Cardiol. 2009, 98, 533-540.
8. Kolbe, I.; Vikmon, M.; Gerlo'czy, A.; Szejthli, J. Preparation and Characterization of Clopidogrel/DIMEB Complex. J. Inclus. Phenom. Macrocycl. Chem. 2002, 44, 183-184.
9. Vogel, A. I. Vogel's Textbook of Macro and Semimicro Qualitative Inorganic Analysis; John Wiley & Sons: New York, 1967; p 291.
10. Fiegl, F. Spot Tests in Organic Analysis; Elsevier: New York, 1975; p 435.
11. Lente, G.; Fabian, I.; Poe, A. J. A Common Misconception about the Eyring Equation. New J. Chem. 2005, 29, 759-760.
12. Bahrami, H.; Zahedi, M. Kinetics and Mechanism of the Oxidation of L-α-Amino-n-butyric Acid in Moderately Concentrated Sulfuric Acid Medium. Can. J. Chem. 2004, 82, 430-436.
13. Chimatadar, S. A.; Hiremath, S. C.; Raju, J. R. Oxidation of Thallium(I) by Permanganate in Perchloric Acid. Indian J. Chem. 1991, 30A, 190-192.
14. Patil, R. K.; Chimatadar, S. A.; Nandibewoor, S. T. Oxidation of Thiosulphate by Hexacyanoferrate(III) in Aqueous Perchloric Acid Medium-A Kinetic and Mechanistic Approach. Indian J. Chem. 2009, 48A, 357-361.
15. Hassan, R. M.; Abdel-Kader, D. A.; Ahmed, S. M.; Fawzy, A.; Zaafarany, I. A.; Asghar, B. H.; Takagi, H. D. Acid-Catalyzed Oxidation of Carboxymethyl Cellulose. Kinetics and Mechanism of Permanganate Oxidation of Carboxymethyl Cellulose in Acid Perchlorate Solutions. Catal. Commun. 2009, 11, 184-190.
16. Bahrami, H.; Zahedi, M. Conclusive Evidence for Delayed Autocatalytic Behaviour of Mn(II) Ions at a Crtical Concentration. J. Iranian Chem. Soc. 2008, 5 (No. 4), 535-545.
17. (a) Abbar, J. C.; Lamani, S. D.; Nandibewoor, S. T. Ruthenium-(III) Catalysed Oxidative Degaradation of Amitriptyline-A Tricyclic AntidepressantDrug by Permanganate inAqueous acidmedium. J. Solution Chem. 2011, 40, 502-520.
18. (b) Timmanagoudar, P. L.; Hiremath, G. A.; Nandibewoor, S. T. Permanganate oxidation of thallium(I) in sulphuric acid: a kinetic study by stopped flow technique. Pol. J. Chem. 1996, 70, 1459-1467.
19. Amis, E. S. Solvent Effects on Reaction Rates and Mechanisms; Academic Press: New York, 1996; p 18.
20. Farokhi, S. A.; Nandibewoor, S. T. The Kinetics and the Mechanism of Oxidative Decarboxylation of Benzilic Acid by Acidic Permanganate (Stopped-Flow Technique)-An Autocatalytic Study. Can. J. Chem. 2004, 82, 1372-1380.