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Volumn 67 A, Issue 5, 2012, Pages 456-464

Chronic inhibition of the respiratory chain in human fibroblast cultures: Differential responses related to subject chronological and biological age

Author keywords

Growth rate; Mitochondria; ROS; Skin fibroblasts; Telomere length

Indexed keywords

BETA GALACTOSIDASE; REACTIVE OXYGEN METABOLITE; ROTENONE;

EID: 84860124221     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glr196     Document Type: Article
Times cited : (10)

References (43)
  • 2
    • 84891713034 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
    • Coppe JP, Patil CK, Rodier F, et al. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 2008;6:2853-2868.
    • (2008) PLoS Biol , vol.6 , pp. 2853-2868
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3
  • 3
    • 39149093357 scopus 로고    scopus 로고
    • Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies
    • Stolzing A, Jones E, McGonagle D, Scutt A. Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies. Mech Ageing Dev. 2008;129:163-173.
    • (2008) Mech Ageing Dev , vol.129 , pp. 163-173
    • Stolzing, A.1    Jones, E.2    McGonagle, D.3    Scutt, A.4
  • 5
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: When bad things happen to good cells
    • DOI 10.1038/nrm2233, PII NRM2233
    • Campisi J, d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol. 2007;8:729-740. (Pubitemid 47312822)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 729-740
    • Campisi, J.1    D'Adda Di Fagagna, F.2
  • 6
    • 35448962513 scopus 로고    scopus 로고
    • A continuous correlation between oxidative stress and telomere shortening in fibroblasts
    • DOI 10.1016/j.exger.2007.08.005, PII S0531556507001714
    • Richter T, von Zglinicki T. A continuous correlation between oxidative stress and telomere shortening in fibroblasts. Exp Gerontol. 2007;42:1039-1042. (Pubitemid 47633455)
    • (2007) Experimental Gerontology , vol.42 , Issue.11 , pp. 1039-1042
    • Richter, T.1    Zglinicki, T.V.2
  • 7
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 8
    • 0036629255 scopus 로고    scopus 로고
    • Oxidative stress shortens telomeres
    • DOI 10.1016/S0968-0004(02)02110-2, PII S0968000402021102
    • von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci. 2002;27:339-344. (Pubitemid 34756516)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.7 , pp. 339-344
    • Von Zglinicki, T.1
  • 9
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • DOI 10.1126/science.1069523
    • Karlseder J, Smogorzewska A, de LT. Senescence induced by altered telomere state, not telomere loss. Science. 2002;295:2446-2449. (Pubitemid 34270257)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    De Lange, T.3
  • 10
    • 73949143673 scopus 로고    scopus 로고
    • Stress-induced responses of human skin fibroblasts in vitro reflect human longevity
    • Dekker P, Maier AB, van HD, et al. Stress-induced responses of human skin fibroblasts in vitro reflect human longevity. Aging Cell. 2009;8:595-603.
    • (2009) Aging Cell , vol.8 , pp. 595-603
    • Dekker, P.1    Maier, A.B.2    Van, H.D.3
  • 12
    • 69549112995 scopus 로고    scopus 로고
    • Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study
    • Westendorp RG, van Heemst D, Rozing MP, et al. Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study. J Am Geriatr Soc. 2009;57:1634-1637.
    • (2009) J Am Geriatr Soc , vol.57 , pp. 1634-1637
    • Westendorp, R.G.1    Van Heemst, D.2    Rozing, M.P.3
  • 13
    • 84857197481 scopus 로고    scopus 로고
    • Familial longevity is marked by enhanced insulin sensitivity
    • Wijsman CA, Rozing MP, Streefland TC, et al. Familial longevity is marked by enhanced insulin sensitivity. Aging Cell. 2010:10-9726.
    • (2010) Aging Cell , pp. 10-9726
    • Wijsman, C.A.1    Rozing, M.P.2    Streefland, T.C.3
  • 15
  • 16
    • 77951953060 scopus 로고    scopus 로고
    • Mammalian mitochondrial complex I: Biogenesis, regulation, and reactive oxygen species generation
    • Koopman WJ, Nijtmans LG, Dieteren CE, et al. Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation. Antioxid Redox Signal. 2010;12:1431-1470.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 1431-1470
    • Koopman, W.J.1    Nijtmans, L.G.2    Dieteren, C.E.3
  • 19
    • 78651306084 scopus 로고    scopus 로고
    • Implications of using the fluorescent probes, dihydrorhodamine 123 and 2',7'-dichlorodihydrofluorescein diacetate, for the detection of UVA-induced reactive oxygen species
    • Boulton S, Anderson A, Swalwell H, Henderson JR, Manning P, Birch-Machin MA. Implications of using the fluorescent probes, dihydrorhodamine 123 and 2',7'-dichlorodihydrofluorescein diacetate, for the detection of UVA-induced reactive oxygen species. Free Radic Res. 2011;45:139-146.
    • (2011) Free Radic Res , vol.45 , pp. 139-146
    • Boulton, S.1    Anderson, A.2    Swalwell, H.3    Henderson, J.R.4    Manning, P.5    Birch-Machin, M.A.6
  • 20
    • 71049171763 scopus 로고    scopus 로고
    • Rapid flow cytometric method for measuring Senescence Associated b-galactosidase activity in human fibroblasts
    • Noppe G, Dekker P, Koning-Treurniet C, et al. Rapid flow cytometric method for measuring Senescence Associated b-galactosidase activity in human fibroblasts. Cytometry A. 2009;75:910-916.
    • (2009) Cytometry A , vol.75 , pp. 910-916
    • Noppe, G.1    Dekker, P.2    Koning-Treurniet, C.3
  • 21
    • 0141483496 scopus 로고    scopus 로고
    • Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts
    • Greco M, Villani G, Mazzucchelli F, Bresolin N, Papa S, Attardi G. Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J. 2003;17:1706-1708.
    • (2003) FASEB J , vol.17 , pp. 1706-1708
    • Greco, M.1    Villani, G.2    Mazzucchelli, F.3    Bresolin, N.4    Papa, S.5    Attardi, G.6
  • 22
    • 0033522924 scopus 로고    scopus 로고
    • Titrating the effects of mitochondrial complex i impairment in the cell physiology
    • Barrientos A, Moraes CT. Titrating the effects of mitochondrial complex I impairment in the cell physiology. J Biol Chem. 1999;274:16188-16197.
    • (1999) J Biol Chem , vol.274 , pp. 16188-16197
    • Barrientos, A.1    Moraes, C.T.2
  • 23
    • 0033732110 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
    • Toussaint O, Medrano EE, von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol. 2000;35:927-945.
    • (2000) Exp Gerontol , vol.35 , pp. 927-945
    • Toussaint, O.1    Medrano, E.E.2    Von Zglinicki, T.3
  • 24
    • 0029127226 scopus 로고
    • Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: A model for senescence?
    • von Zglinicki T, Saretzki G, Docke W, Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp Cell Res. 1995;220:186-193.
    • (1995) Exp Cell Res , vol.220 , pp. 186-193
    • Von Zglinicki, T.1    Saretzki, G.2    Docke, W.3    Lotze, C.4
  • 26
    • 79957924106 scopus 로고    scopus 로고
    • ABC transporters affect the detection of intracellular oxidants by fluorescent probes
    • Prochazkova J, Kubala L, Kotasova H, et al. ABC transporters affect the detection of intracellular oxidants by fluorescent probes. Free Radic Res. 2011;45:779-787.
    • (2011) Free Radic Res , vol.45 , pp. 779-787
    • Prochazkova, J.1    Kubala, L.2    Kotasova, H.3
  • 27
    • 0028342438 scopus 로고
    • Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
    • Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev. 1994;74:121-133.
    • (1994) Mech Ageing Dev , vol.74 , pp. 121-133
    • Sohal, R.S.1    Ku, H.H.2    Agarwal, S.3    Forster, M.J.4    Lal, H.5
  • 28
    • 33744503921 scopus 로고    scopus 로고
    • Intraspecific variation in survival and mitochondrial oxidative phosphorylation in wild-caught Drosophila simulans
    • DOI 10.1111/j.1474-9726.2006.00211.x
    • Melvin RG, Ballard JW. Intraspecific variation in survival and mitochondrial oxidative phosphorylation in wild-caught Drosophila simulans. Aging Cell. 2006;5:225-233. (Pubitemid 43805612)
    • (2006) Aging Cell , vol.5 , Issue.3 , pp. 225-233
    • Melvin, R.G.1    Ballard, J.W.O.2
  • 29
    • 77956190702 scopus 로고    scopus 로고
    • Optimal micronutrients delay mitochondrial decay and age-associated diseases
    • Ames BN. Optimal micronutrients delay mitochondrial decay and age-associated diseases. Mech Ageing Dev. 2010;131:473-479.
    • (2010) Mech Ageing Dev , vol.131 , pp. 473-479
    • Ames, B.N.1
  • 30
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human-cells in culture and in aging skin in-vivo
    • Dimri GP, Lee XH, Basile G, et al. A Biomarker That Identifies Senescent Human-Cells in Culture and in Aging Skin In-Vivo. Proc Natl Acad Sci USA. 1995;92:9363-9367.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.H.2    Basile, G.3
  • 31
    • 0001068487 scopus 로고
    • The relationship between in vitro cellular aging and in vivo human age
    • Schneider EL, Mitsui Y. The relationship between in vitro cellular aging and in vivo human age. Proc Natl Acad Sci USA. 1976;73:3584-3588.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 3584-3588
    • Schneider, E.L.1    Mitsui, Y.2
  • 32
    • 0030743137 scopus 로고    scopus 로고
    • Cell aging in vivo and in vitro
    • DOI 10.1016/S0047-6374(97)00067-5, PII S0047637497000675
    • Rubin H. Cell aging in vivo and in vitro. Mechanisms Mech Ageing Dev. 1997;98:1-35. (Pubitemid 27338452)
    • (1997) Mechanisms of Ageing and Development , vol.98 , Issue.1 , pp. 1-35
    • Rubin, H.1
  • 33
    • 0036346816 scopus 로고    scopus 로고
    • Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages
    • Balin AK, Fisher AJ, Anzelone M, Leong I, Allen RG. Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages. Exp Cell Res. 2002;274:275-287.
    • (2002) Exp Cell Res , vol.274 , pp. 275-287
    • Balin, A.K.1    Fisher, A.J.2    Anzelone, M.3    Leong, I.4    Allen, R.G.5
  • 34
    • 0036420161 scopus 로고    scopus 로고
    • Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
    • Lee HC, Yin PH, Chi CW, Wei YH. Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci. 2002;9:517-526.
    • (2002) J Biomed Sci , vol.9 , pp. 517-526
    • Lee, H.C.1    Yin, P.H.2    Chi, C.W.3    Wei, Y.H.4
  • 35
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin E, Colla S, Liesa M, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011;470:359-365.
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1    Colla, S.2    Liesa, M.3
  • 38
    • 0034737456 scopus 로고    scopus 로고
    • Mitotic misregulation and human aging
    • DOI 10.1126/science.287.5462.2486
    • Ly DH, Lockhart DJ, Lerner RA, Schultz PG. Mitotic misregulation and human aging. Science. 2000;287:2486-2492. (Pubitemid 30185444)
    • (2000) Science , vol.287 , Issue.5462 , pp. 2486-2492
    • Ly, D.H.1    Lockhart, D.J.2    Lerner, R.A.3    Schultz, P.G.4
  • 43
    • 67349173185 scopus 로고    scopus 로고
    • Relation between replicative senescence of human fibroblasts and life history characteristics
    • Maier AB, Westendorp RG. Relation between replicative senescence of human fibroblasts and life history characteristics. Ageing Res Rev. 2009;8:237-243.
    • (2009) Ageing Res Rev , vol.8 , pp. 237-243
    • Maier, A.B.1    Westendorp, R.G.2


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