Tumor cell expression of Heat Shock Protein (HSP) 72 is influenced by HSP72 [HSPA1B A(1267)G] polymorphism and predicts Survival in Small Cell Lung Cancer (SCLC) patients

Cancer Investigation

Volumn 30, Issue 4, 2012, Pages 317-322

  Szondy, Klara ^a   Rusai, Krisztina ^a   Szabó, Attila J ^a   Nagy, Andrea ^a   Gal, Krisztina ^a   Fekete, Andrea ^a   Kovats, Zsuzsanna ^a   Losonczy, Gyorgy ^a   Lukacsovits, József ^a   Müller, Veronika ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

HSP72; Immunohistochemistry; Polymorphism; Prognosis; SCLC

Indexed keywords

ADENOSINE; GUANINE; HEAT SHOCK PROTEIN 72;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER CELL; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; LUNG SMALL CELL CANCER; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; SURVIVAL PREDICTION;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GENE EXPRESSION; HSP70 HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMALL CELL LUNG CARCINOMA;

EID: 84860121190     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.3109/07357907.2012.657815     Document Type: Article

References (30)

1. Tiseo M, Ardizzoni A. Current status of second-line treatment and novel therapies for small cell lung cancer. J Torac Oncol 2007;2:764-772. (Pubitemid 47357534)
2. Hartl FU. Molecular chaperones in cellular protein folding. Nature 1996;381:571-579.
3. Schlesinger MJ. Heat shock proteins. J Biol Chem 1990;265: 12111-12114.
4. Gál K, Cseh A, Szalay B, Rusai K, Vannay A, Lukácsovits J, Hee-mann U, Szabó AJ, Losonczy G, Tamási L, Müller V. Effect of cigarette smoke and dexamethasone on Hsp72 system of alveolar epithelial cells. Cell Stress Chaperones 2011;16:369-378.
5. Bausero MA, Page DT, Osinaga E, Asea A. Surface expression of Hsp25 and Hsp72 diferentially regulates tumor growth and metastasis. Tumour Biol 2004;25:243-251. (Pubitemid 40082326)
6. Chan T, Chen Z, Hao S, Xu S, Yuan J, Saxena A, Qureshi M, Zheng C, Xiang J. Enhanced T-cell immunity induced by dendritic cells with phagocytosis of heat shock protein 70 gene-transfected tumor cells in early phase of apoptosis. Cancer Gene Ter 2007;14:409-420. (Pubitemid 46425784)
7. Enomoto Y, Bharti A, Khaleque AA, Song B, Liu C, Apostolopoulos V, Xing PX, Calderwood SK, Gong J. Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol 2006;177:5946-5955. (Pubitemid 44628808)
8. Malusecka E, Krzyzowska-Gruca S, Gawrychowski J, Fiszer-Kierzkowska A, Kolosza Z, Krawczyk Z. Stress proteins HSP27 and HSP70i predict survival in non-small cell lung carcinoma. Anticancer Res 2008;28:501-506. (Pubitemid 351362860)
9. Pociot F, Ronningen KS, Nerup J. Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM). Scand J Immunol 1993;38:491-495. (Pubitemid 23327292)
10. Fekete A, Vannay A, V́er A, Rusai K, Müller V, Reusz G, Tulassay T, Szabó AJ. Sex diferences in heat shock protein 72 expression and localization in rats following renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 2006;291:F806-811. (Pubitemid 44506977)
11. Fekete A, Treszl A, Toth-Heyn P, Vannay A, Tordai A, Tulassay T, Vasarhelyi B. Association between heat shock protein 72 gene polymorphism and acute renal failure in premature neonates. Pediatr Res 2003;54:452-455. (Pubitemid 37159111)
12. Lewis SJ, Cherry NM, Niven RM, Barber PV, Povey AC. Polymorphisms in the NAD(P)H: quinone oxidoreductase gene and small cell lung cancer risk in a UK population. Lung Cancer 2001;34:177-183. (Pubitemid 33010793)
13. Boldrini L, Ursino S, Gisfredi S, Faviana P, Donati V, Camacci T, Lucchi M, Mussi A, Basolo F, Pingitore R, Fontanini G. Expression and mutational status of c-kit in small-cell lung cancer: prognostic relevance. Clin Cancer Res 2004;10:4101-4108. (Pubitemid 38812489)
14. Dally H, Edler L, Jager B, Schmezer P, Spiegelhalder B, Diene-mann H, Drings P, Schulz V, Kayser K, Bartsch H, Risch A. The CYP3A4*1B allele increases risk for small cell lung cancer: effect of gender and smoking dose. Pharmacogenetics 2003;13:607-618. (Pubitemid 37311147)
15. Wang Y, Zhou F, Wu Y, Xu D, Li W, Liang S. The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer. Clin Chem Lab Med 2010;48:1657-1663.
16. Pockley AG. Heat shock proteins as regulators of the immune response. Lancet 2003;362:469-476. (Pubitemid 36999714)
17. Konno A, Sato N, Yagihashi A, Torigoe T, Cho JM, Torimoto K, Hara I, Wada Y, Okubo M, Takahashi N. Heat-or stress-inducible transformation-associated cell surface antigen on the activated H-ras oncogene-transfected rat fbroblast. Cancer Res 1989;49:6578-6582. (Pubitemid 20008790)
18. Kingston RE, Baldwin AS, Sharp PA. Regulation of heat shock protein 70 gene expression by c-myc. Nature (London) 1984;312:280-282. (Pubitemid 15202006)
19. Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 1988;8:531-539.
20. Agof SN, Hou J, Linzer DI, Wu B. Regulation of the human hsp70 promoter by p53. Science 1993;259:84-87. (Pubitemid 23036091)
21. Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, Jaattela M. Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 2005;19:570-582. (Pubitemid 40314989)
22. Gabai VL, Yaglom JA, Waldman T, Sherman MY. Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. Mol Cell Biol 2009;29:559-569.
23. Sherman M. Major heat shock protein Hsp72 controls oncogene-induced senescence. Ann N Y Acad Sci 2010;1197:152-157.
24. Jaattela M, Wissing D. Heat-shock proteins protect cells from monocyte cytotoxicity: possible mechanism of self-protection. J Exp Med 1993;177:231-236. (Pubitemid 23008106)
25. Michils A, Redivo M, Zegers de Beyl V, de Maertelaer V, Jacobovitz D, Rocmans P, Duchateau J. Increased expression of high but not low molecular weight heat shock proteins in resectable lung carcinoma. Lung Cancer 2001;33:59-67. (Pubitemid 32590792)
26. Hettinga JV, Lemstra W, Meijer C, Los G, de Vries EG, Konings AW, Kampinga HH. Heat-shock protein expression in cisplatin-sensitive and-resistant human tumor cells. Int J Cancer 1996;67:800-807. (Pubitemid 26348808)
27. Mestiri S, Bouaouina N, Ahmed SB, Khedhaier A, Jrad BB, Remadi S, Chouchane L. Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma. Cancer 2001;91:672-678. (Pubitemid 32173290)
28. Zouari Bouassida K, Chouchane L, Jellouli K, Cherif S, Haddad S, Gabbouj S, Danguir J. Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity. Diabetes Metab 2004;30:175-180. (Pubitemid 38715174)
29. Georgiadis MS, Steinberg SM, Hankins LA, Ihde DC, Johnson BE. Obesity and therapy-related toxicity in patients treated for small-cell lung cancer. J Natl Cancer Inst 1995;87:361-366.
30. De Stefani E, Bofetta P, Ronco AL, Brennan P, Correa P, Deneo-Pellegrini H, Gutierrez LP, Mendilaharsu M. Squamous and small cell carcinomas of the lung: similarities and diferences concerning the role of tobacco smoking. Lung Cancer 2005;47:1-8. (Pubitemid 39643236)