Disentangling the coil: Modulation of conformational and dynamic properties by site-directed mutation in the non-native state of hen egg white lysozyme

Biochemistry

Volumn 51, Issue 16, 2012, Pages 3361-3372

  Sziegat, Friederike ^a   Silvers, Robert ^a   Hähnke, Martin ^a   Jensen, Malene Ringkjøbing ^b   Blackledge, Martin ^b   Wirmer Bartoschek, Julia ^a   Schwalbe, Harald ^a  

^a GOETHE UNIVERSITY   (Germany)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPREHENSIVE ANALYSIS; COMPUTATIONAL APPROACH; CONFORMATIONAL ANALYSIS; CONFORMATIONAL ENSEMBLE; DIFFUSION RATE CONSTANTS; DYNAMIC PROPERTY; HEN EGG WHITE LYSOZYME; MODEL PROTEINS; NON-NATIVE STATE; RELAXATION RATES; RESIDUAL DIPOLAR COUPLINGS; SIDE-CHAINS; SITE-DIRECTED MUTATION; SMALL-ANGLE SCATTERING; STRUCTURAL BIOLOGY; WILD TYPES;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; RATE CONSTANTS;

ENZYMES;

EGG WHITE; LYSOZYME;

ANIMAL CELL; ARTICLE; DIFFUSION; HEN; MOLECULAR DYNAMICS; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS; SMALL ANGLE SCATTERING;

EGG WHITE; MURAMIDASE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN DENATURATION; PROTEIN FOLDING;

EID: 84860119435     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300222f     Document Type: Article

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