Evaluation of anti-ulcer activity of Citrullus colocynthis fruit against pylorus ligation induced ulcers in male wistar rats

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue 2, 2012, Pages 446-451

  Prasanth Reddy, V ^a   Sudheshna, G ^a   Afsar, S K ^a   Sai Saran, S ^a   Nelson Kumar, S ^a   Raja Ram, C ^a   Ravindra Reddy, K ^a  

^a P Rami Reddy Memorial College of Pharmacy   (India)

Author keywords

Aqueous extract; Citrullus colocynthis; Ethanolic extract; Flavanoids; Pylorus ligation; Ulcer index

Indexed keywords

ALCOHOL; ALKALOID; COLOCYNTH EXTRACT; FLAVANOID; PLANT EXTRACT; RANITIDINE; SAPONIN; TANNIN; WATER;

ACIDITY; ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CITRULLUS; COLOCYNTH; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; EXPERIMENTAL MODEL; MALE; NONHUMAN; PHYTOCHEMISTRY; PYLORUS LIGATION; RAT; STOMACH JUICE; STOMACH PH; STOMACH ULCER; TOXICITY TESTING; TREATMENT OUTCOME;

EID: 84860006569     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. th Edition; 2001; 334-343
2. Tripathi K D, Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers (P) Ltd. New Delhi; 1999; 628-642.
3. Clouatre D and Rosenbaum M: The Diet and benefits of HCA. Keats Publishing: New York 994; 23-32
4. nd edition; 427
5. Nadkarni, Indian Materia Medica, Popular Prakashan Mumbai, Vol. 1: 419-420
6. th Edition; 1985; 284
7. Warrier P K, Nambiar V P K and Ramankutty C, Indian Medicinal Plants, Orient Longman Ltd., Madras; 1993-1995; Vol. 1-5
8. Nadkarni A K, Indian Materia Medica, Mumbai; 1954
9. Dey A C, Indian Medicinal Plants Used in Ayurvedic Preparations, Bishen Singh, Mahendra Pal Singh, Dehra Dun; 1980; 202
10. Ayoub S.M.H and Yankov L, Two isomeric dimethylexandecan- 14-ol-2-ones from Citrullus colocynthis L. fruit peels. Dokl. Bolg. Akad. Nauk; 1981; 34(6): 795-798
11. Basalah M O, Ali Whaibi M H, and Sher M, Comparative study of some metabolities of Citrullus colocynthis Schrad and Cucumis prophetarum L. J. Biol. Sci. Research; 1985; 16(1): 105-23
12. Habs M, Jahn S A A and Schmaehl D, Carcinogenic activity of condensate from colquint seeds (Citrullus colocynthis) after chronic eipcutaneous administration to mice. J. Cancer Res. Clin. Oncol; 1984; 108(1): 154-156
13. Navot N and Zamir D, Linkage relationships of 19 protein-coding genes in watermelons. Theor. Appl. Genet; 1986; 72(2): 274-278
14. Belsem Marzouk, Zohra Marzouk, Maha Mastouri, Nadia Fenina and Mahjoub Aunis: Comparative evaluation of the antimicrobial activity of Citrullus colocynthis immature fruit and seed organic extracts; African Journal of Biotechnology; 2011; 10(10): 2130-2134
15. Usman Memon, Abdul Hakeem Brohi, Syed Waseemuddin Ahmed Iqbal Azhar And Husan Bano, antibacterial screening of Citrullus colocynthis Pakistan Journal of Pharmaceutical Sciences; 2003; 16 (1): 1-6
16. Shay H, Komarov SA, Fels SS, Meranze D, Grunstein M, Siplet H, A Simple method for uniform production of gastric ulcers in rats, Gastroenterol; 1945; 5: 43-61
17. Shahla Najafi, Nima Sanadgo, Batool Sadeghi Nejad, Maryam Ashofteh Beiragi and Ehsan Sanadgol: Phytochemical screening and antibacterial activity of Citrullus colocynthis (Linn.) Schrad against Staphylococcus aureus Journal of Medicinal Plants Research; 2010; 4(22): 2321-2325
18. Sakat SS, Juvekar RA: Antiulcer Activity of Methanol Extract of Erythrina indica Lam. Leaves in Experimental Animals. Pharmacognosy Research; 2009; 1: 396 401