Pretreatment neutrophil:lymphocyte ratio as a prognostic factor in cervical carcinoma

Anticancer Research

Volumn 32, Issue 4, 2012, Pages 1555-1561

  Lee, Yoo Young ^a   Choi, Chel Hun ^a   Kim, Ha Jeong ^a   Kim, Tae Joong ^a   Lee, Jeong Won ^a   Lee, Je Ho ^a   Bae, Duk Soo ^a   Kim, Byoung Gie ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Biological markers; Lymphocytes; Neutrophils; Prognostic; Survival; Uterine cervical neoplasms

Indexed keywords

TUMOR MARKER;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER MORTALITY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; COST EFFECTIVENESS ANALYSIS; FEMALE; HUMAN; LYMPHOCYTE; MAJOR CLINICAL STUDY; NEUTROPHIL; PREMEDICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; UTERINE CERVIX CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; LYMPHOCYTE COUNT; MIDDLE AGED; NEUTROPHILS; PROGNOSIS; UTERINE CERVICAL NEOPLASMS;

EID: 84859977204     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
2. Global cancer facts and figures. Available at: http://www.cancer.org/ downloads/STT/Global-Cancer-Facts-andFigures-2007-rev.pdf. Last accessed August 22, 2008.
3. Quinn MA, Benedet JL, Odicino F, Maisonneuve P, Beller U, Creasman WT, Heintz AP, Ngan HY and Pecorelli S: Carcinoma of the cervix uteri. FIGO 6th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 95(Suppl 1): S43-103, 2006.
4. Brenner DE, Whitley NO, Prempree T and Villasanta U: An evaluation of the computed tomographic scanner for the staging of carcinoma of the cervix. Cancer 50: 2323-2328, 1982. (Pubitemid 13244167)
5. Van Nagell JR Jr., Roddick JW, Jr. and Lowin DM: The staging of cervical cancer: inevitable discrepancies between clinical staging and pathologic Undinges. Am J Obstet Gynecol 110: 973-978, 1971.
6. Rosa DD, Medeiros LR, Edelweiss MI, Bozzetti MC, Pohlmann PR, Stein AT and Dickinson HO: Adjuvant platinum-based chemotherapy for early stage cervical cancer. Cochrane Database Syst Rev 8: CD005342, 2009.
7. Ugge F, Fuoco G, Lorusso D, Lucidi A, Borriello M, Pisconti S, Scambia G and Ferrandina G: Pharmacotherapy of cervical cancer. Expert Opin Pharmacother 11: 2059-2075, 2010.
8. Suh DH, Kim JW, Aziz MF, Devi UK, Ngan HY, Nam JH, Kim SC, Kato T, Ryu HS, Fujii S, Lee YS, Kim JH, Kim TJ, Kim YT, Wang KL, Lee TS, Ushijima K, Shin SG, Chia YN, Wilailak S, Park SY, Katabuchi H, Kamura T and Kang SB: Asian Society of Gynecologic Oncology workshop 2010. J Gynecol Oncol 21: 137-150, 2010.
9. Balkwill F and Mantovani A: Inflammation and cancer: Back to Virchow? Lancet 357: 539-545, 2001. (Pubitemid 32173595)
10. Mantovani A, Allavena P, Sica A and Balkwill F: Cancer-related inflammation. Nature 454: 436-444, 2008.
11. Schmidt H, Bastholt L, Geertsen P, Christensen IJ, Larsen S, Gehl J and von der Maase H: Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model. Br J Cancer 93: 273-278, 2005. (Pubitemid 43080028)
12. Schmidt H, Suciu S, Punt CJ, Gore M, Kruit W, Patel P, Lienard D, von der Maase H, Eggermont AM and Keilholz U: Pretreatment levels of peripheral neutrophils and leukocytes as independent predictors of overall survival in patients with American Joint Committee on Cancer Stage IV Melanoma: results of the EORTC 18951 Biochemotherapy Trial. J Clin Oncol 25: 1562-1569, 2007. (Pubitemid 46733083)
13. Teramukai S, Kitano T, Kishida Y, Kawahara M, Kubota K, Komuta K, Minato K, Mio T, Fujita Y, Yonei T, Nakano K, Tsuboi M, Shibata K, Furuse K and Fukushima M: Pretreatment neutrophil count as an independent prognostic factor in advanced non-small cell lung cancer: an analysis of Japan Multinational Trial Organisation LC00-03. Eur J Cancer 45: 1950-1958, 2009.
14. Clark EJ, Connor S, Taylor MA, Madhavan KK, Garden OJ and Parks RW: Preoperative lymphocyte count as a prognostic factor in resected pancreatic ductal adenocarcinoma. HPB (Oxford) 9: 456-460, 2007. (Pubitemid 350215042)
15. Zahorec R: Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in the critically ill. Bratisl Uk Listy 102: 5-14, 2001.
16. Walsh SR, Cook EJ, Goulder F, Justin TA and Keeling NJ: Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol 91: 181-184, 2005. (Pubitemid 41254421)
17. Halazun KJ, Hardy MA, Rana AA, Woodland DCt, Luyten EJ, Mahadev S, Witkowski P, Siegel AB, Brown RS Jr. and Emond JC: Negative impact of neutrophil-lymphocyte ratio on outcome after liver transplantation for hepatocellular carcinoma. Ann Surg 250: 141-151, 2009.
18. Bhatti I, Peacock O, Lloyd G, Larvin M and Hall RI: Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio. Am J Surg 30: 30, 2010.
19. Sarraf KM, Belcher E, Raevsky E, Nicholson AG, Goldstraw P and Lim E: Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiovasc Surg 137: 425-428, 2009.
20. Choi CH, Lee YY, Kim MK, Kim TJ, Lee JW, Nam HR, Huh SJ, Lee JH, Bae DS and Kim BG: A matched-case comparison to explore the role of consolidation chemotherapy after concurrent chemoradiation in cervical cancer. Int J Radiat Oncol Biol Phys 81: 1252-1257, 2011.
21. Halazun KJ, Aldoori A, Malik HZ, Al-Mukhtar A, Prasad KR, Toogood GJ and Lodge JP: Elevated preoperative neutrophil to lymphocyte ratio predicts survival following hepatic resection for colorectal liver metastases. Eur J Surg Oncol 34: 55-60, 2008. (Pubitemid 350296756)
22. Liu H, Liu G, Bao Q, Sun W, Bao H, Bi L, Wen W, Liu Y, Wang Z, Yin X, Bai Y and Hu X: The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in rectal carcinoma. J Gastrointest Cancer 41: 116-120, 2010.
23. Kishi Y, Kopetz S, Chun YS, Palavecino M, Abdalla EK and Vauthey JN: Blood neutrophil-to-lymphocyte ratio predicts survival in patients with colorectal liver metastases treated with systemic chemotherapy. Ann Surg Oncol 16: 614-622, 2009.
24. Yamanaka T, Matsumoto S, Teramukai S, Ishiwata R, Nagai Y and Fukushima M: The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in advanced gastric cancer. Oncology 73: 215-220, 2007. (Pubitemid 351630053)
25. Gomez D, Farid S, Malik HZ, Young AL, Toogood GJ, Lodge JP and Prasad KR: Preoperative neutrophil-to-lymphocyte ratio as a prognostic predictor after curative resection for hepatocellular carcinoma. World J Surg 32: 1757-1762, 2008.
26. Porrata LF, Ristow K, Habermann T, Inwards DJ, Micallef IN and Markovic SN: Predicting survival for diffuse large B-cell lymphoma patients using baseline neutrophil/lymphocyte ratio. Am J Hematol 85: 896-899, 2010.
27. Cho H, Hur HW, Kim SW, Kim SH, Kim JH, Kim YT and Lee K: Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment. Cancer Immunol Immunother 58: 15-23, 2009.
28. Fernandes PC, Jr., Garcia CB, Micheli DC, Cunha FQ, Murta EF and Tavares-Murta BM: Circulating neutrophils may play a role in the host response in cervical cancer. Int J Gynecol Cancer 17: 1068-1074, 2007.
29. Choi CH, Kang H, Kim WY, Kim TJ, Lee JW, Huh SJ, Lee JH, Kim BG and Bae DS: Prognostic value of baseline lymphocyte count in cervical carcinoma treated with concurrent chemoradiation. Int J Radiat Oncol Biol Phys 71: 199-204, 2008. (Pubitemid 351491403)
30. Gwak MS, Choi SJ, Kim JA, Ko JS, Kim TH, Lee SM, Park JA and Kim MH: Effects of gender on white blood cell populations and neutrophil-lymphocyte ratio following gastrectomy in patients with stomach cancer. J Korean Med Sci 22(Suppl): S104-108, 2007.
31. Roxburgh CS and McMillan DC: Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future Oncol 6: 149-163, 2010.
32. Pelosof LC and Gerber DE: Paraneoplastic syndromes: an approach to diagnosis and treatment. Mayo Clin Proc 85: 838-854, 2010.
33. Matsumoto Y, Mabuchi S, Muraji M, Morii E and Kimura T: Squamous cell carcinoma of the uterine cervix producing granulocyte colony-stimulating factor: a report of 4 cases and a review of the literature. Int J Gynecol Cancer 20: 417-421, 2010.
34. Mabuchi S, Matsumoto Y, Morii E, Morishige K and Kimura T: The first 2 cases of granulocyte colony-stimulating factor producing adenocarcinoma of the uterine cervix. Int J Gynecol Pathol 29: 483-487, 2010.
35. Romano F, Uggeri F, Crippa S, Di Stefano G, Scotti M, Scaini A and Caprotti R: Immunodeficiency in different histotypes of radically operable gastrointestinal cancers. J Exp Clin Cancer Res 23: 195-200, 2004. (Pubitemid 38943549)
36. Rashid F, Waraich N, Bhatti I, Saha S, Khan RN, Ahmed J, Leeder PC, Larvin M and Iftikhar SY: A preoperative elevated neutrophil: lymphocyte ratio does not predict survival from oesophageal cancer resection. World J Surg Oncol 8: 1, 2010.
37. Pawelec G: Immunosenescence: impact in the young as well as the old? Mech Ageing Dev 108: 1-7, 1999.
38. Castle SC: Clinical relevance of age-related immune dysfunction. Clin Infect Dis 31: 578-585, 2000.
39. Andersen BL, Farrar WB, Golden-Kreutz D, Kutz LA, MacCallum R, Courtney ME and Glaser R: Stress and immune responses after surgical treatment for regional breast cancer. J Natl Cancer Inst 90: 30-36, 1998. (Pubitemid 28078078)
40. Basile S, Angioli R, Manci N, Palaia I, Plotti F and Benedetti Panici P: Gynecological cancers in developing countries: the challenge of chemotherapy in low-resources setting. Int J Gynecol Cancer 16: 1491-1497, 2006. (Pubitemid 44060370)