Species comparison and pharmacological characterization of human, monkey, rat, and mouse TRPA1 channels

Journal of Pharmacology and Experimental Therapeutics

Volumn 341, Issue 2, 2012, Pages 360-368

  Bianchi, Bruce R ^a   Zhang, Xu Feng ^a   Reilly, Regina M ^a   Kym, Philip R ^a   Yao, Betty B ^a   Chen, Jun ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT;

ARTICLE; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; EMBRYO CELL; HUMAN; HUMAN CELL; KIDNEY CELL CULTURE; LIGAND BINDING; MOLECULAR CLONING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SPECIES COMPARISON; SPECIES DIFFERENCE;

ANIMALS; CALCIUM; CELL LINE; DNA, COMPLEMENTARY; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; HAPLORHINI; HEK293 CELLS; HUMANS; LIGANDS; MICE; RATS; SPECIES SPECIFICITY; TRANSFECTION; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84859964383     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.189902     Document Type: Article

References (32)

1. Andersson DA, Gentry C, Moss S, and Bevan S (2008) Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress. J Neurosci 28:2485-2494. (Pubitemid 351348185)
2. Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, and Patapoutian A (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41:849-857. (Pubitemid 38429729)
3. Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Högestätt ED, Julius D, Jordt SE, and Zygmunt PM (2005) Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci USA 102:12248-12252. (Pubitemid 41291160)
4. Bessac BF, Sivula M, von Hehn CA, Escalera J, Cohn L, and Jordt SE (2008) TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest 118: 1899-1910. (Pubitemid 351632392)
5. Bianchi BR, Moreland RB, Faltynek CR, and Chen J (2007) Application of large-scale transiently transfected cells to functional assays of ion channels: different targets and assay formats. Assay Drug Dev Technol 5:417-424. (Pubitemid 47067886)
6. Butelman ER, Harris TJ, and Kreek MJ (2004) Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates. J Pharmacol Exp Ther 311:155-163. (Pubitemid 39287795)
7. Caceres AI, Brackmann M, Elia MD, Bessac BF, del Camino D, D'Amours M, Witek JS, Fanger CM, Chong JA, Hayward NJ, et al. (2009) A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA 106:9099-9104.
8. Chen J and Kym PR (2009) TRPA1: the species difference. J Gen Physiol 133:623-625.
9. Chen J, Lake MR, Sabet RS, Niforatos W, Pratt SD, Cassar SC, Xu J, Gopalakrishnan S, Pereda-Lopez A, Gopalakrishnan M, et al. (2007) Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists. J Biomol Screen 12:61-69. (Pubitemid 46224920)
10. Chen J, Zhang XF, Kort ME, Huth JR, Sun C, Miesbauer LJ, Cassar SC, Neelands T, Scott VE, Moreland RB, et al. (2008) Molecular determinants of species-specific activation or blockade of TRPA1 channels. J Neurosci 28:5063-5071.
11. Chen J, Joshi SK, DiDomenico S, Perner RJ, Mikusa JP, Gauvin DM, Segreti JA, Han P, Zhang XF, Niforatos W, et al. (2011) Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain 152:1165-1172.
12. Cruz-Orengo L, Dhaka A, Heuermann RJ, Young TJ, Montana MC, Cavanaugh EJ, Kim D, and Story GM (2008) Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. Mol Pain 4:30-38.
13. Eid SR, Crown ED, Moore EL, Liang HA, Choong KC, Dima S, Henze DA, Kane SA, and Urban MO (2008) HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain 4:48-57.
14. Hill K and Schaefer M (2007) TRPA1 is differentially modulated by the amphipathic molecules trinitrophenol and chlorpromazine. J Biol Chem 282:7145-7153. (Pubitemid 47093678)
15. Hu E, Calò G, Guerrini R, and Ko MC (2010) Long-lasting antinociceptive spinal effects in primates of the novel nociception/orphanin FQ receptor agonist UFP-112. Pain 148:107-113.
16. Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Högestätt ED, Meng ID, and Julius D (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427:260-265. (Pubitemid 38112043)
17. Kang K, Pulver SR, Panzano VC, Chang EC, Griffith LC, Theobald DL, and Garrity PA (2010) Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception. Nature 464:597-600.
18. Karashima Y, Talavera K, Everaerts W, Janssens A, Kwan KY, Vennekens R, Nilius B, and Voets T (2009) TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci USA 106:1273-1278.
19. Klionsky L, Tamir R, Gao B, Wang W, Immke DC, Nishimura N, and Gavva NR (2007) Species-specific pharmacology of trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists. Mol Pain 3:39-49.
20. Ko MC and Lee H (2002) An experimental model of inflammatory pain in monkeys: comparison of antinociceptive effects of opioids and NSAIDs against carrageenan-induced thermal hyperalgesia, in Abstracts of the 10th World Congress on Pain, San Diego, CA, August 17-22, 2002, p 136, International Association for the Study of Pain Press, Seattle, WA.
21. Kobayashi K, Fukuoka T, Obata K, Yamanaka H, Dai Y, Tokunaga A, and Noguchi K (2005) Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors. J Comp Neurol 493:596-606. (Pubitemid 41780630)
22. Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, and Patapoutian A (2005) The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol 15:929-934. (Pubitemid 40772062)
23. Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, and Patapoutian A (2007) Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445:541-545. (Pubitemid 46197634)
24. Maher M, Ao H, Banke T, Nasser N, Wu NT, Breitenbucher JG, Chaplan SR, and Wickenden AD (2008) Activation of TRPA1 by farnesyl thiosalicylic acid. Mol Pharmacol 73:1225-1234. (Pubitemid 351439204)
25. McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, Zhao M, Hayward NJ, Chong JA, Julius D, Moran MM, et al. (2007) TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 104:13525-13530. (Pubitemid 47293978)
26. Nagatomo K and Kubo Y (2008) Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels. Proc Natl Acad Sci USA 105:17373-17378.
27. Niforatos W, Zhang XF, Lake MR, Walter KA, Neelands T, Holzman TF, Scott VE, Faltynek CR, Moreland RB, and Chen J (2007) Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3′-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597). Mol Pharmacol 71:1209-1216. (Pubitemid 46658674)
28. Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, Dai Y, Fukuoka T, Tokunaga A, Tominaga M, and Noguchi K (2005) TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J Clin Invest 115:2393-2401. (Pubitemid 41266201)
29. Petrus M, Peier AM, Bandell M, Hwang SW, Huynh T, Olney N, Jegla T, and Patapoutian A (2007) A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain 3:40-47.
30. Stevenson GW, Folk JE, Linsenmayer DC, Rice KC, and Negus SS (2003) Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception. J Pharmacol Exp Ther 307:1054-1064. (Pubitemid 37494225)
31. Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, AndrèE, Patacchini R, Cottrell GS, et al. (2007) 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA 104:13519-13524. (Pubitemid 47293977)
32. Xiao B, Dubin AE, Bursulaya B, Viswanath V, Jegla TJ, and Patapoutian A (2008) Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. J Neurosci 28:9640-9651.