Proximal ligand electron donation and reactivity of the cytochrome P450 ferric-peroxo anion

Journal of the American Chemical Society

Volumn 134, Issue 15, 2012, Pages 6673-6684

  Sivaramakrishnan, Santhosh ^a   Ouellet, Hugues ^a   Matsumura, Hirotoshi ^b   Guan, Shenheng ^a   Moënne Loccoz, Pierre ^b   Burlingame, Alma L ^a   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS OF THE PRODUCT; ANION SPECIES; C-C BONDS; CATALYTIC SEQUENCES; COMPOUND I; CONVENTIONAL ACIDS; CYTOCHROME P450; ELECTRON DONATION; HYDROGEN ABSTRACTION; IRON LIGAND; METHYL GROUP; MYCOBACTERIUM TUBERCULOSIS; OXYGEN TRANSFER; RESONANCE RAMAN; SELENOCYSTEINE; SEQUENTIAL OXIDATION; SIDE-CHAINS; SPECTRAL CHANGE; THIOLATES;

ALDEHYDES; AMINO ACIDS; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGEN; IRON ANALYSIS; LIGANDS; ORGANIC COMPOUNDS; PROTONATION;

IONS;

ACID; ALDEHYDE; ANION; CYTOCHROME P450; CYTOCHROME P450 125; DEFORMYLATION; FERRIC ANION; HYDROGEN; IRON; LIGAND; OXYGEN; PEROXO ANION; PEROXYHEMIACETAL; SELENATE; SELENOCYSTEINE; STEROL; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CATALYSIS; CHEMICAL BOND; CONTROLLED STUDY; COVALENT BOND; ELECTRON; ELECTRON SPIN RESONANCE; METABOLITE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON TRANSPORT; RAMAN SPECTROMETRY; REACTION ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRONS; LIGANDS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84859956102     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja211499q     Document Type: Article

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