Antinociceptive and anti-inflammatory activity of alkaloid fraction of trichopus zeylanicus gaertn

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue 2, 2012, Pages 632-635

  Sambath Kumar, R ^a   Perumal, P ^b   Shankar, Bachhav R ^b  

^a JKK Nataraja College of Pharmacy   (India)

^b Department of Pharmaceutical Chemistry ^*  (India)

Author keywords

Anti inflammatory; Antinociceptive; Pentazocine; Trichopus zeylanicus

Indexed keywords

ALKALOID; ANTINOCICEPTIVE AGENT; DICLOFENAC; PENTAZOCINE; PLANT EXTRACT; TRICHOPUS ZEYLANICUS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; GRANULOMA; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PAW EDEMA; PERITONEAL CAVITY; REACTION TIME; SCANNING ELECTRON MICROSCOPY; TRICHOPUS ZEYLANICUS;

EID: 84859948914     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Sharma AK, Pushpangadan P, Chopra CL, Rajasekharan S and Saradmmal L. Adaptogenic activity of seeds of Trichopus zeylanicus Gaertn. The Ginseng of Kerala. Ancient Sci.life.1989; 8: 212-219.
2. Subramonia A, Evans DA, Rajasekharan S and Pushpangadan P. Hepatoprotective activity of Trichopus zeylanicus extract against paracetamol-induced hepatic damage in rat. Indian J. of Exp.Biology. 1998; 36:385-389.
3. Subramoniam A, Madhavachandran V, Rajasekharan S and Pushpangadan P. Aphordisiac property of Trichopus zeylanicus extract in male mice. J. Ethnopharmacol. 1997; 57:21-27.
4. Pushpangadan P, Sharma AK, Rajasekharan S a. Ethnopharmacology of Trichopus zeylanicus The Ginseng of Kerala: a review. In: Pushpangadan P, Nyman U and George, V. Eds., Glimpse of India Ethnopharmacology. TBGRI, Trivandrum, India. 1995, 137-145.
5. Singh B, Gupta DK and Chandan BK (2001). Adaptogenic activity of a glycol-peptido-lipid fraction from the alcoholic extract of Trichopus zeylanicus Gaertn. Phytomed. 8(4): 283-291
6. Tharakan B, Dhanasekaran M and Manyam BV. Antioxidant and DNA protecting properties of anti-fatigue herb Trichopus zeylanicus. Phytother. Res. 2005;19(8):669-673.
7. Mohan VR, Anitha B, Perumalsami Athi and Sutha S. Ethnomedicinal Plants used by the Kanikkars of Tirunelveli District, Tamilnadu, India, to treat skin disease. Ethnobotanical Leaflets. 2008; 12:171-180.
8. Khandelwal KR. Practical Pharmacognosy. Edn 19, Nirali Publication,Pune,India,2008 149-156.
9. Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. Edn 3, Chapman and Hall, London, 2007, 207-208.
10. OECD. Guidelines for the Testing of Chemicals Revised Draft Guideline 423: Acute oral toxicity. 2000
11. Basuri ST. Analgesic activity of stem bark extracts of Sterblus asper. Int. J. Phar. & Pharm. Sci. 2011; 3:219-220.
12. Koster R, Anderson M and De Beer E,. Acetic acid for analgesic screening. Fed.Proc. 1953;18:412-415.
13. Turner RA. Screening Methods in Pharmacology. Edn 2, Academic press, New York. 1971, 100-103.
14. Eddy NB, Leimboeck D. Synthetic analgesic: IIdiethyenylbutennylamines and diethylenylbutylamines. J. Pharmcol. Exp. Therap. 1953; 3:544-547.
15. Lokesh TN Analgesic activity of aqueous and alcohol root extract of Pegularia daemia. Int. J. Phar. & Pharm. Sci. 2009; 1: 33-37.
16. Winter C, Risley E, and Nuss O. Carrageenan -induced inflammation in the hind limb of the rat. Fed. Proc. 1962;46: 118-126.
17. Winter CA, Porter CC. Effect of alteration in side chain upon anti-inflammatory and liver glycogen activities in hydrocortisone esters. J. Ame. Pharmacol.Soc. 1957; 46: 515.
18. Singh S, Majumdar DK. Analgesic activity of Ocimum sanctum and its possible mechanism of action. Int. J. Pharmacog. 1995; 33:188-192.
19. Bentley GA, Newton SH and Starr J. Studies on the antinociceptive action of α- agonists of drugs and their interaction with opioid mechanism. Br. J. Pharmacol. 1983; 79:125-134.
20. Zakaria ZA, Abdul Ghani ZDF, Raden Mohd Nor RNS, Gopalan HK and Suliman Mohd, R et al.,. Antinociceptive, antiinflammatory and antipyretic properties of an aqueous extract of Dicranopteris linearis leaves in experimental animal models. J.Nat.Med. 2008;62:179-187
21. Chapman CR, Casey Kl, Dubner R, Foley KM and Gracely RH et al., Pain measurement: an overview. Pain. 1985;22:1-31.
22. Nemirovsky A, Chen L, Zelman V and Jurna I. The antinociceptive effect of the combination of spinal morphine with systemic morphine or buprenorphine. Ana. Anal. 2001; 93:197-203.
23. Just MJ, Recio MC, Giner RM, Cuellar MJ, and Manez S et al.,.Anti-inflammatory activity of unusal lupine saponin from Bupleurum fruticescens. Planta Medica. 1998;64: 404-407.
24. Di Rosa M, Giroud JP and Willoughby DA. Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J. Pathology. 1971; 104:15-29.
25. Okpo SO, Fatokun F and Adeyemi OO. Analgesic and antiinflammatory activity of Crinum glaucum aqueous extract. J. Ethnopharmacol. 2001; 78:207-211.
26. Vineger R, Schreiber W and Hugo R. Biphasic development of carrageenan edema in rats. J.Pharmacol.Exp. Therap.1969; 166:96-103.
27. Arrigoni ME. Prostaglandins: Possible Mechanism of antiinflammatory Drugs in: Inflammation and Anti-inflammatories. Spectrum Publication, New York, 1977, 119-120
28. Gupta M, Mazumder UK, Gomathi P and Selvan VT. Antiinflammatory evaluation of leaves of plumeria acuminate. BMC Comp. Alt. Med. 2006; 36:1-6.