Analysis of keystone enzyme in agar hydrolysis provides insight into the degradation of a polysaccharide from red seaweeds

Journal of Biological Chemistry

Volumn 287, Issue 17, 2012, Pages 13985-13995

  Hehemann, Jan Hendrik ^a   Smyth, Leo ^a   Yadav, Anuj ^b   Vocadlo, David J ^b   Boraston, Alisdair B ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; BACTEROIDES; CATALYTIC RESIDUE; D-GALACTOSE; GALACTOSE RESIDUES; GLYCOSIDE HYDROLASES; GLYCOSIDIC BOND; HISTIDINE RESIDUES; HUMAN GUTS; MARINE RED ALGA; MICHAELIS COMPLEX; NEOAGARO-OLIGOSACCHARIDES; NEOAGAROBIOSE;

AMINO ACIDS; BACTERIA; CARBOXYLIC ACIDS; CATALYSIS; DEGRADATION; ENZYMES; POLYSACCHARIDES;

ALGAE;

3,6 ANHYDRO ALPHA (1,3) GALACTOSIDASE; 3,6 ANHYDROGALACTOSE; AGAR; ALPHA GALACTOSIDASE; GALACTOSE; GLYCOSIDASE; HISTIDINE; OLIGOSACCHARIDE; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE METABOLISM; CHEMICAL BOND; CONTROLLED STUDY; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SUBSTRATE; HYDROLYSIS; KEYSTONE SPECIES; MOLECULAR RECOGNITION; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL; RED ALGA; RESIDUE ANALYSIS; SEAWEED; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AGAR; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CHROMATOGRAPHY, THIN LAYER; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; GLYCOSIDE HYDROLASES; HYDROLYSIS; MODELS, MOLECULAR; OLIGONUCLEOTIDES; POLYSACCHARIDES; PROTEIN CONFORMATION; PROTEIN FOLDING; SEAWEED; SUBSTRATE SPECIFICITY;

EID: 84859941695     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.345645     Document Type: Article

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