Long-term effects of intravitreal injection of GMP-grade bone-marrow-derived CD34 + cells in NOD-SCID mice with acute ischemia-reperfusion injury

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 2, 2012, Pages 986-994

  Park, Susanna S ^a   Caballero, Sergio ^b   Bauer, Gerhard ^c   Shibata, Bradley ^a   Roth, Alan ^a   Fitzgerald, Paul G ^a   Forward, Krisztina I ^a   Zhou, Ping ^c   McGee, Jeannine ^c   Telander, David G ^a   Grant, Maria B ^b   Nolta, Jan A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CD34+ T LYMPHOCYTE; CELL ISOLATION; CONTROLLED STUDY; ELECTRORETINOGRAPHY; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GOOD MANUFACTURING PRACTICE; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; RETINA ISCHEMIA; SCID MOUSE; T LYMPHOCYTE; ACUTE DISEASE; ANIMAL; BONE MARROW CELL; COMPARATIVE STUDY; CYTOLOGY; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; INTRAVITREAL DRUG ADMINISTRATION; METHODOLOGY; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; RETINA DISEASE; STEM CELL TRANSPLANTATION; TIME; XENOGRAFT;

CD34 ANTIGEN;

ACUTE DISEASE; ANIMALS; ANTIGENS, CD34; BONE MARROW CELLS; ELECTRORETINOGRAPHY; FOLLOW-UP STUDIES; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELLS; HUMANS; INTRAVITREAL INJECTIONS; MICE; MICE, INBRED NOD; MICE, SCID; REPERFUSION INJURY; RETINAL DISEASES; STEM CELL TRANSPLANTATION; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84859940102     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8833     Document Type: Article

References (27)

1. Schachinger V, Zeiher AM. Stem cells and cardiovascular and renal disease: today and tomorrow. J Am Soc Nephrol. 2005;16:S2-S6.
2. Strauer BE, Brehm M, Zeus T, et al. Repair of infracted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation. 2002;106:1913-1918.
3. Jones DG, Anderson ER, Galvin KA. Spinal cord regeneration: moving tentatively towards new perspectives. NeuroRehabilitation. 2003;18:339-351.
4. Otani A, Dorrell MI, Kinder K, et al. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. J Clin Invest. 2004;114:765-774.
5. Cleland JG, Freemantle N, Coletta AP, Clark AL. Clinical trials update from the American Heart Association: REPAIR-AMI, ASTAMI, JELIS, MEGA, REVIVE-II, SURVIVE, and PROACTIVE. Eur J Heart Fail. 2006;8:105-110.
6. Kang HJ, Kim MK, Kim MG, et al. A multicenter, prospective, randomized, controlled trial evaluating the safety and efficacy of intracoronary cell infusion mobilized with granulocyte colonystimulating factor and darbepoetin after acute myocardial infarction: study design and rationale of the "MAGIC cell-5-combination cytokine trial" (Abstract). Trials. 2011;12:33.
7. Zohlnhofer D, Ott I, Mehilli J, et al. Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial. JAMA. 2006;295:1003-1010.
8. Harris JR, Brown GA, Jorgensen M, et al. Bone marrow-derived cells home to and regenerate retinal pigment epithelium after injury. Invest Ophthalmol Vis Sci. 2006;47:2108-2113.
9. Li Y, Reca RG, Atmaca-Sonmez P, et al. Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells. Invest Ophthalmol Vis Sci. 2006;47:1646-1652.
10. Satija NK, Singh Vk, Verma YK, et al. Mesenchymal stem cell-based therapy: a new paradigm in regenerative medicine. J Cell Mol Med. 2009;13:4385-4402.
11. Benoit E, O'Donnell TF Jr, Iafrati MD, et al. The role of amputation as an outcome measure in cellular therapy for critical limb ischemia: implications for clinical trial design. J Transl Med. 2011;9:Art. 165.
12. Lunn JS, Sakowski SA, Federici T, Glass JD, Boulis NM, Feldman EL. Stem cell technology for the study and treatment of motor neuron diseases. Regen Med. 2011;6:201-213.
13. Menasche P. Cardiac cell therapy: lessons from clinical trials. J Mol Cell Cardiol. 2011;50:258-265.
14. Joyce N, Annett G, Wirthlin L, Olson S, Bauer G, Nolta JA. Mesenchymal stem cells for the treatment of neurodegenerative disease. Regen Med. 2010;5:933-946.
15. Meyerrose T, Olson S, Pontow S, et al. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev. 2010;62:1167-1174.
16. Tomita M, Adachi Y, Yamada H, et al. Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina. Stem Cells. 2002;20:279-283.
17. Keizo M, Yasushi A, Haruhiko Y, et al. Long-term survival of bone marrow-derived retinal nerve cells in the retina. Neuro Report. 2005;16:1255-1259.
18. Otani A, Dorrell MI, Kinder K, et al. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. J Clin Invest. 2004;114:765-774.
19. Smith LEH. Bone marrow-derived stem cells preserve cone vision in retinitis pigmentosa. J Clin Invest. 2004;114:755-757.
20. Caballero S, Sengupta N, Afzal A, et al. Ischemic retinal vascular damage can be repaired by healthy, but not diabetic, endothelial progenitor cells. Diabetes. 2007;56:960-967.
21. Jonas JB, Witzens-Harig M, Arseniev L, Ho AD. Intravitreal autologous bone-marrow-derived mononuclear cell transplantation. Acta Ophthalmologica. 2010;88:e131-e132.
22. Siqueira RC, Messias A, Voltarelli JC, Scott IU, Jorge R. Intravitreal injection of autologous bone marrow-derived mononuclear cells for hereditary retinal dystrophy: a phase I trial. Retina. 2011;31: 1207-1214.
23. Zheng L, Gong B, Hatala DA, Kern TS. Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes. Invest Ophthlamol Vis Sci. 2007;48:361-367.
24. Zhou P, Hohm S, Olusanya Y, Hess DA, Nolta J. Human progenitor cells with high aldehyde dehydrogenase activity efficiently engraft into damaged liver in a novel model. Hepatology. 2009;49:1992-2000.
25. Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, Berns A. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 1991;19:4293-4298.
26. Fukuchi Y, Miyakawa Y, Kizaki M, et al. Human acute myeloblastic leukemia-ascites model using the human GM-CSF-and IL-3-releasing transgenic SCID mice. Ann Hematol. 1999;78: 2223-2231.
27. Yuan CC, Miley W, Waters D. A quantification of human cells using an ERV-3 real time PCR assay. J Virol Methods. 2001;91: 109-117.