The times have changed: Molecular pathology is here to stay: A commentary on: Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Lee et al. in this issue

Virchows Archiv

Volumn 460, Issue 2, 2012, Pages 129-130

  Van Krieken, J Han ^a   Hoefler, Gerald ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FORMALDEHYDE; PARAFFIN; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN;

ACCURACY; CODON; COLORECTAL CARCINOMA; DIAGNOSTIC PROCEDURE; DNA EXTRACTION; GENE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; KRAS GENE; METASTASIS; MOLECULAR PATHOLOGY; NOTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TISSUE FIXATION; TISSUE SECTION; TREATMENT OUTCOME; TREATMENT RESPONSE; ADENOCARCINOMA; COLORECTAL TUMOR; GENETICS; METHODOLOGY; NUCLEOTIDE SEQUENCE;

ADENOCARCINOMA; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; HUMANS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 84859934797     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-012-1197-z     Document Type: Note

References (5)

1. van Krieken JH, Jung A, Kirchner T, Carneiro F, Seruca R, Bosman FT, Quirke P, Fléjou JF, Plato Hansen T, de Hertogh G, Jares P, Langner C, HoeflerG, Ligtenberg M, Tiniakos D, Tejpar S, Bevilacqua G, Ensari A (2008) KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. Virchows Arch 453(5):417-431, Epub 2008 Sep 18. Review.
2. Erratum in: Virchows Arch. 2009 Feb; 454(2):233-5
3. Bellon E, Ligtenberg MJ, Tejpar S, Cox K, de Hertogh G, de Stricker K, Edsjö A, Gorgoulis V, Höfler G, Jung A, Kotsinas A, Laurent-Puig P, López-Ríos F, Hansen TP, Rouleau E, Vandenberghe P, van Krieken JJ, Dequeker E (2011) External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds. Oncologist 16(4):467-478, Epub 2011 Mar 26. PubMed PMID: 21441573
4. Dequeker E, Ligtenberg MJ, Vander Borght S, van Krieken JH (2011) Mutation analysis of KRAS prior to targeted therapy in colorectal cancer: development and evaluation of quality by a European external quality assessment scheme. Virchows Arch 459 (2):155-160, Epub 2011 Jun 24. PubMed PMID: 21701884
5. Sung Lee, Victoria H. Brophy, Jianli Cao, Margot Velez, Corey Hoeppner, Stephen Soviero, H. Jeffrey Lawrence (2012) Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma. Virchows Arch. doi:10.1007/s00428-011-1180-0