DNA aptamers against the receptor binding region of hemagglutinin prevent avian influenza viral infection

Molecules and Cells

Volumn 32, Issue 6, 2011, Pages 527-533

  Choi, Seung Kwan ^a   Lee, Changjin ^b   Lee, Kwang Soo ^a   Choe, Soo Young ^c   Mo, In Pil ^c   Seong, Rho Hyun ^b   Hong, Seokmann ^d   Jeon, Sung Ho ^a  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

^c Chungbuk National University   (South Korea)

^d Sejong University   (South Korea)

Author keywords

Anti viral effect; DNA aptamer; H9N2 avian influenza virus; Hemagglutinin

Indexed keywords

APTAMER; COMPLEMENTARY DNA; INFLUENZA VIRUS HEMAGGLUTININ; ANTISERUM; ANTIVIRUS AGENT; HEMAGGLUTININ; PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA; BINDING AFFINITY; BINDING SITE; CELL SURVIVAL; CELL VIABILITY; CLONING; COMBINATORIAL CHEMISTRY; CONSENSUS SEQUENCE; CONTROLLED STUDY; ESCHERICHIA COLI; INFLUENZA VIRUS A H9N2; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RECEPTOR BINDING; SEQUENCE ALIGNMENT; VIRUS PARTICLE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DNA SEQUENCE; DOG; IMMUNOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ORTHOMYXOVIRUS INFECTION; PROTEIN BINDING; PROTEIN DOMAIN;

AVES; AVIAN INFLUENZA VIRUS; MUS; ORTHOMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE; CELL SURVIVAL; CLONING, MOLECULAR; CONSENSUS SEQUENCE; DOGS; HEMAGGLUTININS; IMMUNE SERA; INFLUENZA A VIRUS, H9N2 SUBTYPE; MICE; MOLECULAR SEQUENCE DATA; ORTHOMYXOVIRIDAE INFECTIONS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; SELEX APTAMER TECHNIQUE; SEQUENCE ANALYSIS, DNA;

EID: 84859904415     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-011-0156-x     Document Type: Article

References (37)

1. Ada, G. L., and Jones, P. D. (1986). The immune response to influenza infection. Curr. Top Microbiol. Immunol. 128, 1-54.
2. Alexander, M. E., Moghadas, S. M., Rost, G., and Wu, J. (2008). A delay differential model for pandemic influenza with antiviral treatment. Bull. Math. Biol. 70, 382-397.
3. Cheng, C., Dong, J., Yao, L., Chen, A., Jia, R., Huan, L., Guo, J., Shu, Y., and Zhang, Z. (2008). Potent inhibition of human influenza H5N1 virus by oligonucleotides derived by SELEX. Biochem. Biophys. Res. Commun. 366, 670-674.
4. Choi, J. G., Lee, Y. J., Kim, Y. J., Lee, E. K., Jeong, O. M., Sung, H. W., Kim, J. H., and Kwon, J. H. (2008). An inactivated vaccine to control the current H9N2 low pathogenic avian influenza in Korean J. Vet. Sci. 9, 67-74.
5. Cinatl, J., Jr., Michaelis, M., and Doerr, H. W. (2007). The threat of avian influenza A (H5N1). Part IV: Development of vaccines. Med. Microbiol. Immunol. 196, 213-225. (Pubitemid 350105929)
6. Du, N., Li, W., Li, Y., Liu, S., Sui, Y., Qu, Z., Wang, Y., Du, Y., and Xu, B. (2008). Generation and evaluation of the trivalent inactivated reassortant vaccine using human, avian, and swine influenza A viruses. Vaccine 26, 2912-2918.
7. Fouchier, R. A., Munster, V., Wallensten, A., Bestebroer, T. M., Herfst, S., Smith, D., Rimmelzwaan, G. F., Olsen, B., and Osterhaus, A. D. (2005). Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls. J. Virol. 79, 2814-2822. (Pubitemid 40270559)
8. Gao, X. M., Liew, F. Y., and Tite, J. P. (1989). Identification and characterization of T helper epitopes in the nucleoprotein of influenza A virus. J. Immunol. 143, 3007-3014. (Pubitemid 19281852)
9. Gopinath, S. C., Misono, T. S., Kawasaki, K., Mizuno, T., Imai, M., Odagiri, T., and Kumar, P. K. (2006a). An RNA aptamer that distinguishes between closely related human influenza viruses and inhibits haemagglutinin-mediated membrane fusion. J. Gen. Virol. 87, 479-487.
10. Gopinath, S. C., Sakamaki, Y., Kawasaki, K., and Kumar, P. K. (2006b). An efficient RNA aptamer against human influenza B virus hemagglutinin. J. Biochem. 139, 837-846. (Pubitemid 44014577)
11. He, Q., Velumani, S., Du, Q., Lim, C. W., Ng, F. K., Donis, R., and Kwang, J. (2007). Detection of H5 avian influenza viruses by antigen-capture enzyme-linked immunosorbent assay using H5-specific monoclonal antibody. Clin. Vaccine Immunol. 14, 617-623.
12. Homme, P. J., and Easterday, B. C. (1970). Avian influenza virus infections. I. Characteristics of influenza A-turkey-Wisconsin-1966 virus. Avian Dis. 14, 66-74.
13. James, W. (2007). Aptamers in the virologists' toolkit. J. Gen. Virol. 88, 351-364. (Pubitemid 46210872)
14. Jeon, S. H., and Arnon, R. (2002). Immunization with influenza virus hemagglutinin globular region containing the receptor-binding pocket. Viral. Immunol. 15, 165-176. (Pubitemid 34273446)
15. Jeon, S. H., Kayhan, B., Ben-Yedidia, T., and Arnon, R. (2004). A DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral hemagglutinin. J. Biol. Chem. 279, 48410-48419. (Pubitemid 39540998)
16. Klug, S. J., and Famulok, M. (1994). All you wanted to know about SELEX. Mol. Biol. Rep. 20, 97-107.
17. Lin, Y. P., Shaw, M., Gregory, V., Cameron, K., Lim, W., Klimov, A., Subbarao, K., Guan, Y., Krauss, S., Shortridge, K., et al. (2000). Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates. Proc. Natl. Acad. Sci. USA 97, 9654-9658. (Pubitemid 30650831)
18. Lipatov, A. S., Govorkova, E. A., Webby, R. J., Ozaki, H., Peiris, M., Guan, Y., Poon, L., and Webster, R. G. (2004). Influenza: emergence and control. J. Virol. 78, 8951-8959. (Pubitemid 39096507)
19. Lu, X., Renshaw, M., Tumpey, T. M., Kelly, G. D., Hu-Primmer, J., and Katz, J. M. (2001). Immunity to influenza A H9N2 viruses induced by infection and vaccination. J. Virol. 75, 4896-4901. (Pubitemid 32381532)
20. Matrosovich, M. N., Krauss, S., and Webster, R. G. (2001). H9N2 influenza A viruses from poultry in Asia have human virus-like receptor specificity. Virology 281, 156-162. (Pubitemid 32881133)
21. Park, M., Jeon, S. H., Mo, I. P., and Choi, S. Y. (2008). Interaction of DNA Aptamers with Avian Influenza Virus H9 peptide. J. Biomed. Res. 9, 10.
22. Peiris, M., Yuen, K. Y., Leung, C. W., Chan, K. H., Ip, P. L., Lai, R. W., Orr, W. K., and Shortridge, K. F. (1999). Human infection with influenza H9N2. Lancet 354, 916-917. (Pubitemid 29424025)
23. Roth, J., Zuber, C., Park, S., Jang, I., Lee, Y., Kysela, K. G., Le Fourn, V., Santimaria, R., Guhl, B., and Cho, J. W. (2010). Protein N-glycosylation, protein folding, and protein quality control. Mol. Cells 30, 497-506.
24. Shamah, S. M., Healy, J. M., and Cload, S. T. (2008). Complex target SELEX. Acc. Chem. Res. 41, 130-138.
25. Skehel, J. J., and Wiley, D. C. (2000). Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu. Rev. Biochem. 69, 531-569.
26. Sorrell, E. M., Ramirez-Nieto, G. C., Gomez-Osorio, I. G., and Perez, D. R. (2007). Genesis of pandemic influenza. Cytogenet. Genome Res. 117, 394-402. (Pubitemid 47202702)
27. Sorrell, E. M., Wan, H., Araya, Y., Song, H., and Perez, D. R. (2009). Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus. Proc. Natl. Acad. Sci. USA 106, 7565-7570.
28. Thomas, J. K., and Noppenberger, J. (2007). Avian influenza: a review. Am. J. Health Syst. Pharm. 64, 149-165. (Pubitemid 46395689)
29. Tuerk, C., and Gold, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510.
30. Virelizier, J. L. (1975). Host defenses against influenza virus: the role of anti-hemagglutinin antibody. J. Immunol. 115, 434-439.
31. Wan, H., and Perez, D. R. (2007). Amino acid 226 in the hemagglutinin of H9N2 influenza viruses determines cell tropism and replication in human airway epithelial cells. J. Virol. 81, 5181-5191. (Pubitemid 46744428)
32. Weis, W., Brown, J. H., Cusack, S., Paulson, J. C., Skehel, J. J., and Wiley, D. C. (1988). Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 333, 426-431.
33. Wilson, I. A., and Cox, N. J. (1990). Structural basis of immune recognition of influenza virus hemagglutinin. Annu. Rev. Immunol. 8, 737-771. (Pubitemid 20135645)
34. Wilson, I. A., Skehel, J. J., and Wiley, D. C. (1981). Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution. Nature 289, 366-373.
35. Wong, S. S., and Yuen, K. Y. (2006). Avian influenza virus infections in humans. Chest 129, 156-168. (Pubitemid 43265257)
36. Wu, R., Sui, Z. W., Zhang, H. B., Chen, Q. J., Liang, W. W., Yang, K. L., Xiong, Z. L., Liu, Z. W., Chen, Z., and Xu, D. P. (2008). Characterization of a pathogenic H9N2 influenza A virus isolated from central China in 2007. Arch. Virol. 153, 1549-1555.
37. Zuker, M. (2003). Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31, 3406-3415. (Pubitemid 37442169)