History and current concepts in the pathogenesis of PML

Cleveland Clinic Journal of Medicine

Volumn 78, Issue SUPPL. 2, 2011, Pages

  Major, Eugene O ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; NATALIZUMAB; VIRUS DNA;

ARTICLE; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; JC VIRUS; POLYOMAVIRUS INFECTION; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; VIROLOGY; VIRUS INFECTION;

ANTIBODIES, MONOCLONAL, HUMANIZED; DNA, VIRAL; HUMANS; JC VIRUS; LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL; POLYOMAVIRUS INFECTIONS; TUMOR VIRUS INFECTIONS;

EID: 84859900243     PISSN: 08911150     EISSN: None     Source Type: Journal    
DOI: 10.3949/ccjm.78.s2.02     Document Type: Article

References (20)

1. Astrom KE, Mancall EL, Richardson EP Jr. Progressive multifocal leukoencephalopathy; a hitherto unrecognized complication of chronic lymphatic leukaemia and Hodgkin's disease. Brain 1958; 81:93-111.
2. Hallervorden J. Eigennartige und nicht rubriziebare Prozesse. In: Bumke O, ed. Handbuch der Geiteskranheiten. Vol. 2. Die Anatomie der Psychosen. Berlin: Springer; 1930:1063-1107.
3. Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ, Dessel BH. Cultivation of a papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1971; 1:1257-1260.
4. Major EO, Amemiya K, Tornatore CS, Houff SA, Berger JR. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain. Clin Microbiol Rev 1992; 5:49-73.
5. Walker D, Padgett B. The epidemiology of human polyomaviruses. In: Sever J, Madden D, eds. Polyomaviruses and Human Neurological Disease. New York, NY: Alan R. Liss, Inc.; 1983:99-106.
6. Ryschkewitsch C, Jensen P, Hou J, Fahle G, Fischer S, Major EO. Comparison of PCR-southern hybridization and quantitative realtime PCR for the detection of JC and BK viral nucleotide sequences in urine and cerebrospinal fluid. J Virol Methods 2004; 121:217-221.
7. Monaco MC, Jensen PN, Hou J, Durham LC, Major EO. Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. J Virol 1998; 72:9918-9923.
8. Major EO. Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies. Annu Rev Med 2010; 61:35-47.
9. Imperiale M, Major E. Polyomavirus. In: Knipe D, Howley P, eds. Field Virology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007:2263-2298.
10. Langer-Gould A, Atlas SW, Green AJ, Bollen AW, Pelletier D. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N Engl J Med 2005; 353:375-381.
11. Van Assche G, Van Ranst M, Sciot R, et al. Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N Engl J Med 2005; 353:362-368.
12. Kleinschmidt-DeMasters BK, Tyler KL. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med 2005; 353:369-374.
13. Bozic C, Belcher G, Kooijmans-Coutinho M, et al. Natalizumab utilization and safety in patients with relapsing multiple sclerosis: updated results from TOUCH™ and TYGRIS. Paper presented at: 60th Annual Meeting of the American Academy of Neurology; April 15, 2008; Chicago, IL.
14. Kappos L, Bates D, Hartung HP, et al. Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring. Lancet Neurol 2007; 6:431-441.
15. Major EO. Reemergence of PML in natalizumab-treated patients- new cases, same concerns. N Engl J Med 2009; 361:1041-1043.
16. Vugmeyster Y, Kikuchi T, Lowes MA, et al. Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin. Clin Immunol 2004; 113:38-46.
17. Guttman-Yassky E, Vugmeyster Y, Lowes MA, et al. Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness. J Invest Dermatol 2008; 128:1182-1191.
18. Carson KR, Evens AM, Richey EA, et al. Progressive multif ocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. Blood 2009; 113:4834-4840.
19. Ryschkewitsch CF, Jensen PN, Monaco MC, Major EO. JC virus persistence following progressive multifocal leukoencephalopathy in multiple sclerosis patients treated with natalizumab. Ann Neurol 2010; 68:384-391.
20. Koralnik IJ, Du Pasquier RA, Kuroda MJ, et al. Association of prolonged survival in HLA-A2+ progressive multifocal leuko encephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. J Immunol 2002; 168:499-504.