A pilot study of discontinuous, insulin-like growth factor 1-dosing growth hormone treatment in young children with FGFR3 N540K-mutated hypochondroplasia

Journal of Pediatrics

Volumn 160, Issue 5, 2012, Pages 849-853

  Rothenbuhler, Anya ^a   Linglart, Agns ^a   Piquard, Catherine ^a   Bougnres, Pierre ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

GH; Growth hormone; IGF 1; Insulin like growth factor 1; L4 L1; Ratio of interpedicular distances at the fourth and first lumbar vertebrae; Recombinant growth hormone; rGH; SHR; Sitting height to height ratio

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; HUMAN GROWTH HORMONE; SOMATOMEDIN C;

ARTICLE; BODY BUILD; BODY GROWTH; BODY HEIGHT; CHILD; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; DISEASE SEVERITY; DRUG DOSE REGIMEN; DRUG DOSE TITRATION; FEMALE; GENE MUTATION; HORMONAL THERAPY; HORMONE BLOOD LEVEL; HUMAN; HYPOCHONDROPLASIA; MALE; MUTATIONAL ANALYSIS; OPEN STUDY; PILOT STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; TREATMENT OUTCOME; TREATMENT RESPONSE;

BODY HEIGHT; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DWARFISM; FEMALE; FOLLOW-UP STUDIES; FRANCE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MUTATION; OSTEOCHONDRODYSPLASIAS; PILOT PROJECTS; RARE DISEASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 84859896453     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2011.10.023     Document Type: Article

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